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lytF lytF yddH yddH lytE lytE yebA yebA yycO yycO pgdS pgdS cwlO cwlO yvcN yvcN cwlS cwlS ykfC ykfC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
lytFgamma-D-glutamate-meso-diaminopimelate muropeptidase (major autolysin); Cell wall hydrolase that cleaves gamma-D-glutamate-meso- diaminopimelate bonds in peptidoglycan. LytF is necessary and sufficient for vegetative daughter cell separation, and also seems to play a role in cell autolysis. (488 aa)
yddHCell wall hydrolase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the peptidase C40 family. (329 aa)
lytECell wall hydrolase; Cell wall hydrolase that cleaves gamma-D-glutamate-meso- diaminopimelate bonds in peptidoglycan (By similarity). Seems to play a role in cell separation during vegetative growth. (334 aa)
yebAConserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. (737 aa)
yycOConserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. (245 aa)
pgdSgamma-DD-glutamyl hydrolase (PGA depolymerase); Cleaves, in an endo-type manner, the gamma-glutamyl bond between D-glutamate and L-glutamate of poly-gamma-glutamate (PGA). (413 aa)
cwlOSecreted cell wall DL-endopeptidase; The C-terminal part of CwlO shows a cell wall hydrolytic DL- endopeptidase activity; Belongs to the peptidase C40 family. (473 aa)
yvcNPutative acetyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the arylamine N-acetyltransferase family. (254 aa)
cwlSPeptidoglycan hydrolase (cell wall-binding d,l-endopeptidase); Probably functions as a cell separation enzyme in addition to LytE and LytF. (414 aa)
ykfCgamma-D-glutamyl-L-diaminoacid endopeptidase; Specifically hydrolyzes gamma-D-glutamyl-L-lysine bonds in murein peptides, releasing L-Ala-D-Glu. (296 aa)
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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