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ydfP ydfP yfmJ yfmJ catD catD catE catE mhqA mhqA hmp hmp rtbJ rtbJ yodC yodC yodD yodD yodE yodE yqjM yqjM yrpB yrpB yvaB yvaB padC padC hxlB hxlB hxlA hxlA bsdB bsdB bsdC bsdC bsdD bsdD nfrAB nfrAB ydfO ydfO ycnE ycnE ydfN ydfN yabJ yabJ
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
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gene neighborhood
gene fusions
gene co-occurrence
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textmining
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ydfPPutative membrane bound oxidoreductase; Putative oxidoreductase that may contribute to the degradation of aromatic compounds. (129 aa)
yfmJPutative oxidoreductase; Putative quinone oxidoreductase that may contribute to the degradation of aromatic compounds; Belongs to the NADP-dependent oxidoreductase L4BD family. (339 aa)
catDCatechol-2,3-dioxygenase membrane subunit; Essential for growth and viability in the presence of catechol and probably involved in the detoxification of catechol. (134 aa)
catECatechol-2,3-dioxygenase subunit; Involved in the meta cleavage of catechol to 2-hydroxymuconic semialdehyde. Essential for growth and viability in the presence of catechol and probably involved in the detoxification of catechol. (285 aa)
mhqAPutative hydroquinone-specific extradiol dioxygenase; Putative ring-cleavage dioxygenase that may contribute to the degradation of aromatic compounds. (316 aa)
hmpFlavohemoglobin; Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity). In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (399 aa)
rtbJAntitoxin of ribonuclease RttI; Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity. Confers resistance to catechol, 2- methylhydroquinone (2-MHQ), and diamide. Probably could also reduce benzoquinones produce by the auto-oxidation of catechol and 2- methylhydroquinone. (208 aa)
yodCPutative oxidoreductase; Putative nitroreductase that may contribute to the degradation of aromatic compounds. (202 aa)
yodDPutative hydrolase; Putative hydrolase that may contribute to the degradation of aromatic compounds. (200 aa)
yodEPutative lyase/dioxygenase; Putative ring-cleavage dioxygenase that may contribute to the degradation of aromatic compounds. (303 aa)
yqjMNADPH-dependent flavin oxidoreductase; Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes; Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily. (338 aa)
yrpBPutative anionic nitroalkane dioxygenase; Nitronate monooxygenase that uses molecular oxygen to catalyze the oxidative denitrification of alkyl nitronates. Acts on propionate 3-nitronate (P3N), the presumed physiological substrate. Probably functions in the detoxification of P3N, a metabolic poison produced by plants and fungi as a defense mechanism. (347 aa)
yvaBNADH:dichloroindophenol oxidoreductase; Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity. Confers resistance to catechol, 2- methylhydroquinone (2-MHQ), and diamide. Probably could also reduce benzoquinones produce by the auto-oxidation of catechol and 2- methylhydroquinone. (211 aa)
padCPhenolic acid decarboxylase; Involved in the decarboxylation and detoxification of phenolic derivatives. It is able to catalyze the decarboxylation of ferulic, p-coumaric and caffeic acids; Belongs to the PadC family. (161 aa)
hxlB6-phospho-3-hexuloisomerase (PHI); Catalyzes the isomerization between 3-hexulose 6-phosphate and fructose 6-phosphate. Together with HxlA, may act as a formaldehyde detoxification system. (185 aa)
hxlA3-hexulose-6-phosphate synthase (HPS); Catalyzes the condensation of ribulose 5-phosphate with formaldehyde to form 3-hexulose 6-phosphate. Together with HxlB, may act as a formaldehyde detoxification system; Belongs to the HPS/KGPDC family. HPS subfamily. (210 aa)
bsdBPhenolic acid decarboxylase subunit BsdB; Involved in the non-oxidative decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for phenolic acid decarboxylase (By similarity); Belongs to the UbiX/PAD1 family. YclB subfamily. (204 aa)
bsdCPhenolic acid decarboxylase subunit BsdC; Involved in the non-oxidative decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. Phenolic acid decarboxylase that catalyzes the reversible decarboxylation of 4- hydroxybenzoate and vanillate. Could also catalyze the decarboxylation of salicylate (Probable). Is not active on di- and tri-hydroxybenzoate derivatives. Belongs to the UbiD family. YclC subfamily. (473 aa)
bsdDPhenolic acid decarboxylase subunit BsdD; Involved in the non-oxidative decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions, however the precise biochemical function of BsdD in metabolism of phenolic acid is unknown. (75 aa)
nfrABNADPH-FMN oxidoreductase (nitroreductase); Reduces FMNH(2) to FMN, with NADH or NADPH as reductant. It also reduces nitroaromatic compounds, quinones, chromates and azo dyes. It could supply the reduced form of FMN to luciferase-like protein and contribute to the degradation of aromatic compounds. Belongs to the flavin oxidoreductase frp family. (249 aa)
ydfOPutative dioxygenase; Putative ring-cleavage dioxygenase that may contribute to the degradation of aromatic compounds. (312 aa)
ycnEConserved hypothetical protein; Putative monooxygenase that may contribute to the degradation of aromatic compounds; Belongs to the LsrG family. (95 aa)
ydfNPutative oxidoreductase; Putative nitroreductase that may contribute to the degradation of aromatic compounds. (206 aa)
yabJAminoacrylate/iminopropionate hydrolase/deaminase; Accelerates the release of ammonia from reactive enamine/imine intermediates of the PLP-dependent threonine dehydratase (IlvA) in the low water environment of the cell. It catalyzes the deamination of enamine/imine intermediates to yield 2-ketobutyrate and ammonia. It is required for the detoxification of reactive intermediates of IlvA due to their highly nucleophilic abilities. Involved in the isoleucine biosynthesis. May have a role in the purine metabolism; Belongs to the RutC family. (125 aa)
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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