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kdgK kdgK gntR gntR uxaC uxaC uxuA uxuA uxuB uxuB xynB xynB kdgA kdgA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
kdgK2-keto-3-deoxygluconate kinase; Catalyzes the phosphorylation of 2-keto-3-deoxygluconate (KDG) to produce 2-keto-3-deoxy-6-phosphogluconate (KDPG). Belongs to the carbohydrate kinase PfkB family. (324 aa)
gntRTranscriptional regulator (GntR family); Transcriptional repressor of the gluconate operon (gntRKPZ), which encodes the proteins for gluconate utilization. Represses mRNA synthesis by binding to the gnt operator; the binding is suppressed by gluconate or glucono-delta-lactone. (243 aa)
uxaCGalacturonate isomerase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme. (473 aa)
uxuAD-mannonate dehydratase; Catalyzes the dehydration of D-mannonate; Belongs to the mannonate dehydratase family. (359 aa)
uxuBFructuronate reductase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (278 aa)
xynBXylan beta-1,4-xylosidase; Evidence 1a: Function experimentally demonstrated in the studied strain; enzyme; Belongs to the glycosyl hydrolase 43 family. (533 aa)
kdgA2-keto-3-deoxygluconate-6-phosphate aldolase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme. (196 aa)
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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