STRINGSTRING
amyE amyE immR immR sacV sacV yddG yddG rapI rapI phrI phrI yddM yddM sspB sspB recA recA pheA pheA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
amyEAlpha-amylase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the glycosyl hydrolase 13 family. (659 aa)
immRPhage element (ICEBs1)transcriptional regulator (Xre family); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type h: extrachromosomal origin. (127 aa)
sacVTranscriptional regulator; Required for the excision of the integrative and conjugative element ICEBs1. Excision of ICEBs1 requires two sites, attL and attR, at the left and right ends of the integrated ICEBs1. (64 aa)
yddGConserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. (815 aa)
rapIResponse regulator aspartate phosphatase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type r: regulator; Belongs to the RAP family. (391 aa)
phrISecreted regulator of the activity of phosphatase RapI; Inhibitor of the activity of phosphatase RapI. (39 aa)
yddMPutative helicase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme. (313 aa)
sspBSmall acid-soluble spore protein (beta-type SASP); SASP are bound to spore DNA. They are double-stranded DNA- binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light. (67 aa)
recAMultifunctional SOS repair factor; Multifunctional protein involved in homologous recombination, DNA repair and competence. Can catalyze the hydrolysis of (d)ATP in the presence of single-stranded DNA; prefers dATP at least in vitro, catalyzes the dATP-dependent uptake of single- stranded DNA by duplex DNA, and the dATP-dependent hybridization of homologous single-stranded DNAs (strand exchange). RecA-ATP cannot catalyze homologous DNA strand exchange; SsbA and DprA activate strand exchange by RecA-ATP. It interacts with LexA causing its activation and leading to its autocatalytic clea [...] (348 aa)
pheAPrephenate dehydratase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme. (285 aa)
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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