node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
fumC | odhA | BSU33040 | BSU19370 | Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 2-oxoglutarate dehydrogenase (E1 subunit); E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2). | 0.941 |
fumC | recA | BSU33040 | BSU16940 | Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | Multifunctional SOS repair factor; Multifunctional protein involved in homologous recombination, DNA repair and competence. Can catalyze the hydrolysis of (d)ATP in the presence of single-stranded DNA; prefers dATP at least in vitro, catalyzes the dATP-dependent uptake of single- stranded DNA by duplex DNA, and the dATP-dependent hybridization of homologous single-stranded DNAs (strand exchange). RecA-ATP cannot catalyze homologous DNA strand exchange; SsbA and DprA activate strand exchange by RecA-ATP. It interacts with LexA causing its activation and leading to its autocatalytic clea [...] | 0.844 |
hmp | narJ | BSU13040 | BSU37260 | Flavohemoglobin; Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity). In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. | Nitrate reductase molybdenum cofactor assembly chaperone NarJ; Chaperone required for proper molybdenum cofactor insertion and final assembly of the membrane-bound respiratory nitrate reductase. Belongs to the NarJ/NarW family. | 0.466 |
hmp | nsrR | BSU13040 | BSU09380 | Flavohemoglobin; Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity). In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. | NO-dependent activator of the ResDE regulon; Nitric oxide-responsive transcriptional regulator. It represses the expression of flavohemoprotein hmp and the nitrite reductase nasD. Probably plays a role in the up-regulation of the resDE regulon in the presence of nitric oxide. | 0.984 |
hmp | resD | BSU13040 | BSU23120 | Flavohemoglobin; Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity). In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. | Two-component response regulator; Member of the two-component regulatory system ResD/ResE. Required for the expression of resA, ctaA, qcrABC and fnr; activation role in global regulation of aerobic and anaerobic respiration. | 0.835 |
hmp | resE | BSU13040 | BSU23110 | Flavohemoglobin; Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity). In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. | Two-component sensor histidine kinase; Member of the two-component regulatory system ResD/ResE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates ResD. | 0.831 |
narJ | hmp | BSU37260 | BSU13040 | Nitrate reductase molybdenum cofactor assembly chaperone NarJ; Chaperone required for proper molybdenum cofactor insertion and final assembly of the membrane-bound respiratory nitrate reductase. Belongs to the NarJ/NarW family. | Flavohemoglobin; Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity). In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. | 0.466 |
nsrR | hmp | BSU09380 | BSU13040 | NO-dependent activator of the ResDE regulon; Nitric oxide-responsive transcriptional regulator. It represses the expression of flavohemoprotein hmp and the nitrite reductase nasD. Probably plays a role in the up-regulation of the resDE regulon in the presence of nitric oxide. | Flavohemoglobin; Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity). In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. | 0.984 |
nsrR | resD | BSU09380 | BSU23120 | NO-dependent activator of the ResDE regulon; Nitric oxide-responsive transcriptional regulator. It represses the expression of flavohemoprotein hmp and the nitrite reductase nasD. Probably plays a role in the up-regulation of the resDE regulon in the presence of nitric oxide. | Two-component response regulator; Member of the two-component regulatory system ResD/ResE. Required for the expression of resA, ctaA, qcrABC and fnr; activation role in global regulation of aerobic and anaerobic respiration. | 0.843 |
nsrR | resE | BSU09380 | BSU23110 | NO-dependent activator of the ResDE regulon; Nitric oxide-responsive transcriptional regulator. It represses the expression of flavohemoprotein hmp and the nitrite reductase nasD. Probably plays a role in the up-regulation of the resDE regulon in the presence of nitric oxide. | Two-component sensor histidine kinase; Member of the two-component regulatory system ResD/ResE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates ResD. | 0.830 |
odhA | fumC | BSU19370 | BSU33040 | 2-oxoglutarate dehydrogenase (E1 subunit); E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2). | Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.941 |
recA | fumC | BSU16940 | BSU33040 | Multifunctional SOS repair factor; Multifunctional protein involved in homologous recombination, DNA repair and competence. Can catalyze the hydrolysis of (d)ATP in the presence of single-stranded DNA; prefers dATP at least in vitro, catalyzes the dATP-dependent uptake of single- stranded DNA by duplex DNA, and the dATP-dependent hybridization of homologous single-stranded DNAs (strand exchange). RecA-ATP cannot catalyze homologous DNA strand exchange; SsbA and DprA activate strand exchange by RecA-ATP. It interacts with LexA causing its activation and leading to its autocatalytic clea [...] | Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.844 |
resD | hmp | BSU23120 | BSU13040 | Two-component response regulator; Member of the two-component regulatory system ResD/ResE. Required for the expression of resA, ctaA, qcrABC and fnr; activation role in global regulation of aerobic and anaerobic respiration. | Flavohemoglobin; Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity). In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. | 0.835 |
resD | nsrR | BSU23120 | BSU09380 | Two-component response regulator; Member of the two-component regulatory system ResD/ResE. Required for the expression of resA, ctaA, qcrABC and fnr; activation role in global regulation of aerobic and anaerobic respiration. | NO-dependent activator of the ResDE regulon; Nitric oxide-responsive transcriptional regulator. It represses the expression of flavohemoprotein hmp and the nitrite reductase nasD. Probably plays a role in the up-regulation of the resDE regulon in the presence of nitric oxide. | 0.843 |
resD | resE | BSU23120 | BSU23110 | Two-component response regulator; Member of the two-component regulatory system ResD/ResE. Required for the expression of resA, ctaA, qcrABC and fnr; activation role in global regulation of aerobic and anaerobic respiration. | Two-component sensor histidine kinase; Member of the two-component regulatory system ResD/ResE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates ResD. | 0.999 |
resE | hmp | BSU23110 | BSU13040 | Two-component sensor histidine kinase; Member of the two-component regulatory system ResD/ResE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates ResD. | Flavohemoglobin; Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity). In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. | 0.831 |
resE | nsrR | BSU23110 | BSU09380 | Two-component sensor histidine kinase; Member of the two-component regulatory system ResD/ResE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates ResD. | NO-dependent activator of the ResDE regulon; Nitric oxide-responsive transcriptional regulator. It represses the expression of flavohemoprotein hmp and the nitrite reductase nasD. Probably plays a role in the up-regulation of the resDE regulon in the presence of nitric oxide. | 0.830 |
resE | resD | BSU23110 | BSU23120 | Two-component sensor histidine kinase; Member of the two-component regulatory system ResD/ResE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates ResD. | Two-component response regulator; Member of the two-component regulatory system ResD/ResE. Required for the expression of resA, ctaA, qcrABC and fnr; activation role in global regulation of aerobic and anaerobic respiration. | 0.999 |