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icd icd AF_0681 AF_0681 AF_0682 AF_0682 AF_0683 AF_0683 sdhD sdhD mdh mdh AF_1098 AF_1098 AF_1099 AF_1099 AF_1340 AF_1340 sucD1 sucD1 sucC1 sucC1 AF_1727 AF_1727 sucD2 sucD2 sucC2 sucC2 AF_2366 AF_2366
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
icdIsocitrate dehydrogenase, NADP (icd); Similar to GB:J02799 SP:P08200 PID:146432 GB:U00096 PID:1651560 percent identity: 57.18; identified by sequence similarity; putative; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (412 aa)
AF_0681Succinate dehydrogenase, flavoprotein subunit A (sdhA); Similar to GP:1524302 percent identity: 48.23; identified by sequence similarity; putative. (563 aa)
AF_0682Succinate dehydrogenase, iron-sulfur subunit B (sdhB); Similar to GB:X70908 PID:396212 percent identity: 51.27; identified by sequence similarity; putative. (236 aa)
AF_0683Succinate dehydrogenase, subunit C (sdhC); Similar to GP:1524299 percent identity: 36.56; identified by sequence similarity; putative. (124 aa)
sdhDSuccinate dehydrogenase, subunit D (sdhD); Membrane-anchoring subunit of succinate dehydrogenase (SDH). (117 aa)
mdhL-malate dehydrogenase, NAD+-dependent (mdhA); Catalyzes the reversible oxidation of malate to oxaloacetate. Can also oxidize tartrate. (294 aa)
AF_1098Fumarase (fum-1); Similar to GB:L77117 SP:Q58034 PID:1591328 percent identity: 49.13; identified by sequence similarity; putative. (180 aa)
AF_1099Fumarase (fum-2); Similar to GB:L77117 SP:Q58690 PID:1591932 percent identity: 53.38; identified by sequence similarity; putative. (272 aa)
AF_1340Citrate synthase (citZ); Similar to GB:U05257 SP:P39120 PID:487433 PID:2293267 GB:AL009126 percent identity: 50.27; identified by sequence similarity; putative. (372 aa)
sucD1succinyl-CoA synthetase, alpha subunit (sucD-1); Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (291 aa)
sucC1succinyl-CoA synthetase, beta subunit (sucC-1); Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (383 aa)
AF_1727Malate oxidoreductase (mae); Similar to GP:1006839 percent identity: 52.30; identified by sequence similarity; putative. (456 aa)
sucD2succinyl-CoA synthetase, alpha subunit (sucD-2); Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (287 aa)
sucC2succinyl-CoA synthetase, beta subunit (sucC-2); Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (380 aa)
AF_2366Aspartate aminotransferase (aspB-1); Similar to GB:L77117 SP:Q60317 PID:1592252 percent identity: 42.31; identified by sequence similarity; putative. (373 aa)
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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