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| | Abm4_0065 | LSM domain-containing protein. (67 aa) |
| | rps15 | Ribosomal protein S15P Rps15p. (132 aa) |
| | Abm4_0133 | SAM-dependent methyltransferase. (203 aa) |
| | tbp | TATA-box binding protein Tbp; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation. (181 aa) |
| | rps19e | Ribosomal protein S19e Rps19e; May be involved in maturation of the 30S ribosomal subunit. Belongs to the eukaryotic ribosomal protein eS19 family. (146 aa) |
| | Abm4_0197 | DNA-binding protein; Belongs to the PDCD5 family. (120 aa) |
| | Abm4_0198 | tRNA methyltransferase subunit. (194 aa) |
| | rpl39e | Ribosomal protein L39e Rpl39e; Belongs to the eukaryotic ribosomal protein eL39 family. (51 aa) |
| | rpl31e | Ribosomal protein L31e Rpl31e; Belongs to the ribosomal protein L31e family. (88 aa) |
| | eif6 | Translation initiation factor aIF-6; Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex. (224 aa) |
| | rplX | Ribosomal protein LX RplX. (74 aa) |
| | ftsY | Signal recognition particle receptor FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). (506 aa) |
| | rps3ae | Ribosomal protein S3Ae Rps3ae; Belongs to the eukaryotic ribosomal protein eS1 family. (191 aa) |
| | Abm4_0236 | AAA family ATPase CDC48 subfamily. (738 aa) |
| | tfe | Transcription initiation factor TFIIE alpha subunit Tfe; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabili [...] (151 aa) |
| | secE | Preprotein translocase subunit SecE; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. (59 aa) |
| | spt5 | Ribosomal protein L24 family; Stimulates transcription elongation; Belongs to the archaeal Spt5 family. (160 aa) |
| | rpl11 | Ribosomal protein L11P Rpl11p; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family. (161 aa) |
| | rpl1 | Ribosomal protein L1P Rpl1p; Binds directly to 23S rRNA. Probably involved in E site tRNA release. (212 aa) |
| | rpl10 | Acidic ribosomal protein P0 RplPO; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (336 aa) |
| | rpl12 | Ribosomal protein L12P Rpl12p; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the eukaryotic ribosomal protein P1/P2 family. (100 aa) |
| | rpoH | DNA-directed RNA polymerase subunit H RpoH; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family. (81 aa) |
| | rpoB | DNA-directed RNA polymerase subunit B RpoB; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1117 aa) |
| | rpoA1 | DNA-directed RNA polymerase subunit A' RpoA1; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (869 aa) |
| | rpoA2 | DNA-directed RNA polymerase subunit A'' RpoA2; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (423 aa) |
| | rpl30e | Ribosomal protein L30e Rpl30e; Belongs to the eukaryotic ribosomal protein eL30 family. (99 aa) |
| | nusA | Transcription elongation factor NusA-like protein; Participates in transcription termination. Belongs to the NusA family. (143 aa) |
| | rps12 | Ribosomal protein S12P Rps12p; With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family. (141 aa) |
| | rps7 | Ribosomal protein S7P Rps7p; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center; Belongs to the universal ribosomal protein uS7 family. (187 aa) |
| | fusA | Translation elongation factor aEF-2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF [...] (730 aa) |
| | tuf | Translation elongation factor aEF-1 alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. (413 aa) |
| | rps10 | Ribosomal protein S10P Rps10p; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (102 aa) |
| | Abm4_0408 | Hypothetical protein. (272 aa) |
| | Abm4_0444 | H/ACA RNA-protein complex component Gar1. (93 aa) |
| | tfb | Transcription initiation factor TFIIB Tfb; Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB). (310 aa) |
| | prf1 | Peptide chain release factor aRF1; Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. (411 aa) |
| | eif5a | Translation initiation factor eIF-5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family. (135 aa) |
| | Abm4_0487 | GTP-binding protein. (345 aa) |
| | Abm4_0489 | Peptidase U62 family. (455 aa) |
| | Abm4_0515 | Hypothetical protein. (211 aa) |
| | hel308 | DEAD/DEAH box helicase domain-containing protein; DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks. (694 aa) |
| | rps17e | Ribosomal protein S17e Rps17e; Belongs to the eukaryotic ribosomal protein eS17 family. (64 aa) |
| | Abm4_0561 | SAM-dependent methyltransferase UbiE family. (226 aa) |
| | rpl7ae | Ribosomal protein L7Ae Rpl7ae; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs. (123 aa) |
| | rps28e | Ribosomal protein S28e Rps28e; Belongs to the eukaryotic ribosomal protein eS28 family. (68 aa) |
| | rpl24e | Ribosomal protein L24e Rpl24e; Binds to the 23S rRNA. (53 aa) |
| | infB | Translation initiation factor IF-2; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2. (595 aa) |
| | rps6e | Ribosomal protein S6e Rps6e; Belongs to the eukaryotic ribosomal protein eS6 family. (126 aa) |
| | eif2g | Translation initiation factor aIF-2 gamma subunit; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily. (410 aa) |
| | Abm4_0716 | Hypothetical protein. (128 aa) |
| | rps24e | Ribosomal protein S24e Rps24e; Belongs to the eukaryotic ribosomal protein eS24 family. (103 aa) |
| | Abm4_0798 | LSM domain-containing protein; Belongs to the snRNP Sm proteins family. (77 aa) |
| | rpl37e | Ribosomal protein L37e Rpl37e; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL37 family. (61 aa) |
| | rpl40e | Ribosomal protein L40e Rpl40e; Belongs to the eukaryotic ribosomal protein eL40 family. (48 aa) |
| | Abm4_0915 | Ribosomal biogenesis protein; Probably involved in the biogenesis of the ribosome. (171 aa) |
| | Abm4_0916 | DNA-directed RNA polymerase subunit P RpoP. (43 aa) |
| | rpl37ae | Ribosomal protein L37Ae Rpl37ae; Binds to the 23S rRNA. (87 aa) |
| | rrp42 | Exosome complex RNA-binding protein Rrp42; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site. (263 aa) |
| | rrp41 | Exosome complex exonuclease Rrp41. (243 aa) |
| | rrp4 | Exosome complex RNA-binding protein Rrp4; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome. (334 aa) |
| | Abm4_0921 | Exosome subunit. (233 aa) |
| | psmA | Proteasome alpha subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. (263 aa) |
| | Abm4_0926 | Ribosomal protein L15e Rpl15e. (184 aa) |
| | pan | Proteasome-activating nucleotidase; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase- [...] (414 aa) |
| | Abm4_0977 | HTH domain-containing protein. (163 aa) |
| | tfs1 | Transcription factor S Tfs1; Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (106 aa) |
| | Abm4_1031 | Helicase. (973 aa) |
| | srp19 | Signal recognition particle SRP19 protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP. (95 aa) |
| | Abm4_1139 | DEAD/DEAH box helicase domain-containing protein; Belongs to the DEAD box helicase family. (432 aa) |
| | rps8e | Ribosomal protein S8e Rps8e. (125 aa) |
| | proS | prolyl-tRNA synthetase ProS; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). (469 aa) |
| | rps2p | Ribosomal protein S2P Rps2p; Belongs to the universal ribosomal protein uS2 family. (200 aa) |
| | rpoK | DNA-directed RNA polymerase subunit K RpoK; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit family. (60 aa) |
| | rpoN | DNA-directed RNA polymerase subunit N RpoN. (56 aa) |
| | rps9p | Ribosomal protein S9P Rps9p; Belongs to the universal ribosomal protein uS9 family. (132 aa) |
| | rpl13 | Ribosomal protein L13P Rpl13p; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (140 aa) |
| | rpl18e | Ribosomal protein L18e Rpl18e; Belongs to the eukaryotic ribosomal protein eL18 family. (121 aa) |
| | rpoD | DNA-directed RNA polymerase subunit D RpoD; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (267 aa) |
| | rps11 | Ribosomal protein S11P Rps11p; Located on the platform of the 30S subunit. Belongs to the universal ribosomal protein uS11 family. (130 aa) |
| | rps4p | Ribosomal protein S4P Rps4p; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (180 aa) |
| | rps13 | Ribosomal protein S13P Rps13p; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement; Belongs to the universal ribosomal protein uS13 family. (153 aa) |
| | cbf5p | H/ACA RNA-protein complex component Cbf5p; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily. (320 aa) |
| | Abm4_1248 | Ribosomal protein L14e Rpl14e. (73 aa) |
| | cmk | Cytidylate kinase Cmk. (172 aa) |
| | rpl34e | Ribosomal protein L34e Rpl34e; Belongs to the eukaryotic ribosomal protein eL34 family. (88 aa) |
| | secY | Preprotein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. (453 aa) |
| | rpl15 | Ribosomal protein L15P Rpl15p; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (145 aa) |
| | rpl30 | Ribosomal protein L30P Rpl30p. (152 aa) |
| | rps5p | Ribosomal protein S5P Rps5p; With S4 and S12 plays an important role in translational accuracy. (214 aa) |
| | rpl18 | Ribosomal protein L18P Rpl18p; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (193 aa) |
| | rpl19e | Ribosomal protein L19e Rpl19e; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family. (149 aa) |
| | Abm4_1259 | Ribosomal protein L32e Rpl32e. (108 aa) |
| | rpl6p | Ribosomal protein L6P Rpl6p; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (178 aa) |
| | rps8p | Ribosomal protein S8P Rps8p; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (130 aa) |
| | rps14 | Ribosomal protein S14P Rps14p; Binds 16S rRNA, required for the assembly of 30S particles. (47 aa) |
| | rpl5p | Ribosomal protein L5P Rpl5p; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (171 aa) |
| | rps4e | Ribosomal protein S4e Rps4e; Belongs to the eukaryotic ribosomal protein eS4 family. (241 aa) |
| | rpl24 | Ribosomal protein L24P Rpl24p; Located at the polypeptide exit tunnel on the outside of the subunit. (116 aa) |
| | rpl14 | Ribosomal protein L14P Rpl14p; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (132 aa) |
| | rps17 | Ribosomal protein S17P Rps17p; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (105 aa) |
| | Abm4_1269 | Translation initiation factor aSUI1; Belongs to the SUI1 family. (115 aa) |
| | rpl29 | Ribosomal protein L29P Rpl29p; Belongs to the universal ribosomal protein uL29 family. (68 aa) |
| | rps3p | Ribosomal protein S3P Rps3p; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family. (254 aa) |
| | rpl22 | Ribosomal protein L22P Rpl22p; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome. (154 aa) |
| | rps19p | Ribosomal protein S19P Rps19p; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (136 aa) |
| | rpl2p | Ribosomal protein L2P Rpl2p; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (241 aa) |
| | rpl23 | Ribosomal protein L23P Rpl23p; Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Belongs to the universal ribosomal protein uL23 family. (86 aa) |
| | rpl4p | Ribosomal protein L4p Rpl4p; Forms part of the polypeptide exit tunnel. (254 aa) |
| | rpl3p | Ribosomal protein L3P Rpl3p; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. (336 aa) |
| | Abm4_1326 | Hypothetical protein. (167 aa) |
| | rrmJ | Ribosomal RNA large subunit methyltransferase J RrmJ; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. (202 aa) |
| | eif2b | Translation initiation factor aIF-2 beta subunit; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-beta/eIF-5 family. (137 aa) |
| | Abm4_1392 | NMD3 family protein. (352 aa) |
| | Abm4_1456 | ATPase RIL. (591 aa) |
| | Abm4_1459 | RNA-binding protein. (53 aa) |
| | ef1b | Translation elongation factor aEF-1 beta; Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA. (88 aa) |
| | eif1a | Translation initiation factor aIF-1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. (104 aa) |
| | Abm4_1470 | Serine/threonine protein kinase RIO1 family. (264 aa) |
| | Abm4_1472 | RNA-binding protein. (199 aa) |
| | Abm4_1503 | Ribosomal protein L10e Rpl10e. (160 aa) |
| | psmB | Proteasome beta subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. (208 aa) |
| | Abm4_1560 | pre-mRNA splicing ribonucleoprotein PRP31. (405 aa) |
| | flpA | Fibrillarin FlpA; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family. (216 aa) |
| | map | Methionine aminopeptidase Map; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val); Belongs to the peptidase M24A family. Methionine aminopeptidase archaeal type 2 subfamily. (311 aa) |
| | nop10 | H/ACA RNA-protein complex component Nop10p; Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA. (53 aa) |
| | eif2a | Translation initiation factor aIF-2 alpha subunit; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-alpha family. (265 aa) |
| | rps27e | Ribosomal protein S27e Rps27e. (59 aa) |
| | rpl44e | Ribosomal protein L44e Rpl44e; Binds to the 23S rRNA. (92 aa) |
| | tfs2 | Transcription factor S Tfs2; Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (105 aa) |
| | rpoL | DNA-directed RNA polymerase subunit L RpoL; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoL/eukaryotic RPB11/RPC19 RNA polymerase subunit family. (94 aa) |
| | csl4 | Exosome complex RNA-binding protein Csl4; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs. (189 aa) |
| | srp54 | Signal recognition particle SRP54 protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. (446 aa) |
| | rpl21e | Ribosomal protein L21e Rpl21e; Belongs to the eukaryotic ribosomal protein eL21 family. (96 aa) |
| | Abm4_1668 | NUDIX domain-containing protein. (133 aa) |
| | Abm4_1676 | ATP-dependent DNA helicase. (621 aa) |
