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hmd hmd mtd mtd Abm4_0064 Abm4_0064 Abm4_0123 Abm4_0123 fdhA fdhA fdhB fdhB fwdH fwdH fwdF fwdF fwdG fwdG fwdD fwdD fwdB fwdB fwdA fwdA fwdC fwdC fwdE fwdE nrpR nrpR Abm4_0179 Abm4_0179 cofE1 cofE1 Abm4_0433 Abm4_0433 Abm4_0482 Abm4_0482 Abm4_0504 Abm4_0504 Abm4_0505 Abm4_0505 mptG1 mptG1 mptG2 mptG2 Abm4_0635 Abm4_0635 hdrC1 hdrC1 hdrB1 hdrB1 hdrA1 hdrA1 mfnB mfnB Abm4_0774 Abm4_0774 frhB2 frhB2 mvhD2 mvhD2 fdhB2 fdhB2 fdhA2 fdhA2 hisAF hisAF ftr1 ftr1 ehaA ehaA citG citG mch mch Abm4_1291 Abm4_1291 hdrB2 hdrB2 hdrC2 hdrC2 mer mer Abm4_1429 Abm4_1429 Abm4_1458 Abm4_1458 Abm4_1483 Abm4_1483 atwA atwA dusA2 dusA2 mvhB mvhB mvhA mvhA mvhG mvhG mvhD mvhD Abm4_1515 Abm4_1515 cobY cobY Abm4_1517 Abm4_1517 mtrH mtrH mtrG mtrG mtrF mtrF mtrA mtrA mtrB mtrB mtrC mtrC mtrD mtrD mtrE mtrE mcrA mcrA mcrG mcrG mcrC mcrC mcrD mcrD mcrB mcrB Abm4_1531 Abm4_1531 Abm4_1572 Abm4_1572 ftr2 ftr2 frhB1 frhB1 frhG frhG frhD frhD afpA afpA hdrA2 hdrA2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
hmdCoenzyme F420-dependent N(5),N(10)-methenyltetrahydromethanopterin reductase Hmd; Catalyzes the reversible reduction of methenyl-H(4)MPT(+) to methylene-H(4)MPT. (339 aa)
mtdF420-dependent methylenetetrahydromethanopterin dehydrogenase Mtd; Catalyzes the reversible reduction of methenyl-H(4)MPT(+) to methylene-H(4)MPT. (276 aa)
Abm4_0064Methanogenesis marker protein 12; Belongs to the UPF0285 family. (334 aa)
Abm4_0123Hydrogenase expression/formation related protein. (457 aa)
fdhAFormate dehydrogenase alpha subunit FdhA. (688 aa)
fdhBFormate dehydrogenase beta subunit FdhB. (411 aa)
fwdHTungsten formylmethanofuran dehydrogenase subunit H FwdH. (155 aa)
fwdFTungsten formylmethanofuran dehydrogenase subunit F FwdF. (367 aa)
fwdGTungsten formylmethanofuran dehydrogenase subunit G FwdG. (76 aa)
fwdDTungsten formylmethanofuran dehydrogenase subunit D FwdD. (188 aa)
fwdBTungsten formylmethanofuran dehydrogenase subunit B FwdB. (458 aa)
fwdATungsten formylmethanofuran dehydrogenase subunit A FwdA. (574 aa)
fwdCTungsten formylmethanofuran dehydrogenase subunit C FwdC. (288 aa)
fwdETungsten formylmethanofuran dehydrogenase subunit E FwdE. (190 aa)
nrpRTranscriptional repressor of nif and glnA operons NrpR. (564 aa)
Abm4_0179Chorismate lyase. (189 aa)
cofE1F420-0:gamma-glutamyl ligase CofE1. (305 aa)
Abm4_0433ATP-grasp domain-containing protein. (424 aa)
Abm4_0482Hypothetical protein. (211 aa)
Abm4_0504Hypothetical protein. (385 aa)
Abm4_0505H4MPT-linked C1 transfer pathway protein. (347 aa)
mptG1Beta-ribofuranosylaminobenzene 5'-phosphate synthase MptG1; Catalyzes the condensation of 4-aminobenzoate (pABA) with 5- phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta- ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P). (329 aa)
mptG2Beta-ribofuranosylaminobenzene 5'-phosphate synthase MptG2; Catalyzes the condensation of 4-aminobenzoate (pABA) with 5- phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta- ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P). (331 aa)
Abm4_0635Hypothetical protein. (213 aa)
hdrC1CoB--CoM heterodisulfide reductase subunit C HdrC1. (204 aa)
hdrB1CoB--CoM heterodisulfide reductase subunit B HdrB1. (348 aa)
hdrA1CoB--CoM heterodisulfide reductase subunit A HdrA1; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). (776 aa)
mfnBHypothetical protein; Catalyzes the formation of 4-(hydroxymethyl)-2- furancarboxaldehyde phosphate (4-HFC-P) from two molecules of glyceraldehyde-3-P (GA-3-P). (238 aa)
Abm4_0774Methyl-coenzyme M reductase component A2-like protein. (574 aa)
frhB2Coenzyme F420 hydrogenase beta subunit FrhB2. (360 aa)
mvhD2Methyl viologen-reducing hydrogenase delta subunit MvhD2. (129 aa)
fdhB2Formate dehydrogenase beta subunit FdhB2. (385 aa)
fdhA2Formate dehydrogenase alpha subunit FdhA2. (343 aa)
hisAFhisA/hisF family protein HisAF; Belongs to the HisA/HisF family. (228 aa)
ftr1Formylmethanofuran-tetrahydromethanopterin formyltransferase Ftr1. (297 aa)
ehaAEnergy-converting hydrogenase A subunit A EhaA. (107 aa)
citGATP:dephospho-CoA triphosphoribosyl transferase CitG. (302 aa)
mchMethenyltetrahydromethanopterin cyclohydrolase Mch; Catalyzes the reversible interconversion of 5-formyl-H(4)MPT to methenyl-H(4)MPT(+); Belongs to the MCH family. (322 aa)
Abm4_12914Fe-4S ferredoxin iron-sulfur binding domain-containing protein. (328 aa)
hdrB2CoB--CoM heterodisulfide reductase subunit B HdrB2. (294 aa)
hdrC2CoB--CoM heterodisulfide reductase subunit C HdrC2. (347 aa)
mer5,10-methylenetetrahydromethanopterin reductase Mer; Catalyzes the reversible reduction of methylene-H(4)MPT to methyl-H(4)MPT; Belongs to the mer family. (321 aa)
Abm4_1429Dihydropteroate synthase-related protein. (545 aa)
Abm4_1458Aspartate/glutamate/uridylate kinase. (223 aa)
Abm4_1483Methanogenesis marker protein 9. (163 aa)
atwAMethyl-coenzyme M reductase component A2 AtwA. (536 aa)
dusA2tRNA-dihydrouridine synthase DusA2. (236 aa)
mvhBMethyl viologen-reducing hydrogenase beta subunit MvhB. (415 aa)
mvhAMethyl viologen-reducing hydrogenase alpha subunit MvhA; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. (474 aa)
mvhGMethyl viologen-reducing hydrogenase gamma subunit MvhG. (309 aa)
mvhDMethyl viologen-reducing hydrogenase delta subunit MvhD. (139 aa)
Abm4_1515PRC-barrel domain-containing protein. (89 aa)
cobYGTP:adenosylcobinamide-phosphate guanylyltransferase CobY. (206 aa)
Abm4_1517Methanogenesis marker protein 14. (491 aa)
mtrHTetrahydromethanopterin S-methyltransferase subunit H MtrH. (313 aa)
mtrGTetrahydromethanopterin S-methyltransferase subunit G MtrG; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. (83 aa)
mtrFTetrahydromethanopterin S-methyltransferase subunit F MtrF. (68 aa)
mtrATetrahydromethanopterin S-methyltransferase subunit A MtrA; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step; Belongs to the MtrA family. (241 aa)
mtrBTetrahydromethanopterin S-methyltransferase subunit B MtrB; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. (108 aa)
mtrCTetrahydromethanopterin S-methyltransferase subunit C MtrC; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. (263 aa)
mtrDTetrahydromethanopterin S-methyltransferase subunit D MtrD; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. (233 aa)
mtrETetrahydromethanopterin S-methyltransferase subunit E MtrE; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. (293 aa)
mcrAMethyl-coenzyme M reductase alpha subunit McrA; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis. (551 aa)
mcrGMethyl-coenzyme M reductase gamma subunit McrG. (249 aa)
mcrCMethyl-coenzyme M reductase C subunit McrC. (198 aa)
mcrDMethyl-coenzyme M reductase D subunit McrD. (151 aa)
mcrBMethyl-coenzyme M reductase beta subunit McrB. (443 aa)
Abm4_1531Methanogenesis marker protein 10. (423 aa)
Abm4_1572Hypothetical protein. (357 aa)
ftr2Formylmethanofuran-tetrahydromethanopterin formyltransferase Ftr2; Catalyzes the reversible transfer of a formyl group from formylmethanofuran (formyl-MFR) to tetrahydromethanopterin (H(4)MPT) so as to produce 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) and methanofuran (MFR); Belongs to the FTR family. (293 aa)
frhB1Coenzyme F420 hydrogenase beta subunit FrhB1. (292 aa)
frhGCoenzyme F420 hydrogenase gamma subunit FrhG. (271 aa)
frhDCoenzyme F420 hydrogenase delta subunit FrhD. (159 aa)
afpAArchaeoflavoprotein AfpA. (235 aa)
hdrA2CoB--CoM heterodisulfide reductase subunit A HdrA2; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). (660 aa)
Your Current Organism:
Methanobrevibacter sp. AbM4
NCBI taxonomy Id: 224719
Other names: M. sp. AbM4
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