(12 nodes) Ribosome biogenesis, and snoRNA binding network (Methanobrevibacter sp. AbM4)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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Your Input:
	eif6	Translation initiation factor aIF-6; Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex. (224 aa)
	Abm4_0444	H/ACA RNA-protein complex component Gar1. (93 aa)
	Abm4_0487	GTP-binding protein. (345 aa)
	rpl7ae	Ribosomal protein L7Ae Rpl7ae; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs. (123 aa)
	Abm4_0915	Ribosomal biogenesis protein; Probably involved in the biogenesis of the ribosome. (171 aa)
	rps8e	Ribosomal protein S8e Rps8e. (125 aa)
	cbf5p	H/ACA RNA-protein complex component Cbf5p; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily. (320 aa)
	rrmJ	Ribosomal RNA large subunit methyltransferase J RrmJ; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. (202 aa)
	Abm4_1392	NMD3 family protein. (352 aa)
	Abm4_1560	pre-mRNA splicing ribonucleoprotein PRP31. (405 aa)
	flpA	Fibrillarin FlpA; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family. (216 aa)
	nop10	H/ACA RNA-protein complex component Nop10p; Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA. (53 aa)

Your Current Organism:

Methanobrevibacter sp. AbM4

NCBI taxonomy Id: 224719
Other names: M. sp. AbM4

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Abm4_0444	Abm4_0487	Abm4_0444	Abm4_0487	H/ACA RNA-protein complex component Gar1.	GTP-binding protein.	0.604
Abm4_0444	Abm4_1392	Abm4_0444	Abm4_1392	H/ACA RNA-protein complex component Gar1.	NMD3 family protein.	0.557
Abm4_0444	Abm4_1560	Abm4_0444	Abm4_1560	H/ACA RNA-protein complex component Gar1.	pre-mRNA splicing ribonucleoprotein PRP31.	0.945
Abm4_0444	cbf5p	Abm4_0444	Abm4_1245	H/ACA RNA-protein complex component Gar1.	H/ACA RNA-protein complex component Cbf5p; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.	0.994
Abm4_0444	flpA	Abm4_0444	Abm4_1561	H/ACA RNA-protein complex component Gar1.	Fibrillarin FlpA; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family.	0.737
Abm4_0444	nop10	Abm4_0444	Abm4_1641	H/ACA RNA-protein complex component Gar1.	H/ACA RNA-protein complex component Nop10p; Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA.	0.992
Abm4_0444	rpl7ae	Abm4_0444	Abm4_0709	H/ACA RNA-protein complex component Gar1.	Ribosomal protein L7Ae Rpl7ae; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.	0.986
Abm4_0444	rps8e	Abm4_0444	Abm4_1147	H/ACA RNA-protein complex component Gar1.	Ribosomal protein S8e Rps8e.	0.417
Abm4_0487	Abm4_0444	Abm4_0487	Abm4_0444	GTP-binding protein.	H/ACA RNA-protein complex component Gar1.	0.604
Abm4_0487	Abm4_0915	Abm4_0487	Abm4_0915	GTP-binding protein.	Ribosomal biogenesis protein; Probably involved in the biogenesis of the ribosome.	0.932
Abm4_0487	Abm4_1392	Abm4_0487	Abm4_1392	GTP-binding protein.	NMD3 family protein.	0.977
Abm4_0487	Abm4_1560	Abm4_0487	Abm4_1560	GTP-binding protein.	pre-mRNA splicing ribonucleoprotein PRP31.	0.976
Abm4_0487	cbf5p	Abm4_0487	Abm4_1245	GTP-binding protein.	H/ACA RNA-protein complex component Cbf5p; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.	0.877
Abm4_0487	eif6	Abm4_0487	Abm4_0201	GTP-binding protein.	Translation initiation factor aIF-6; Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex.	0.959
Abm4_0487	flpA	Abm4_0487	Abm4_1561	GTP-binding protein.	Fibrillarin FlpA; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family.	0.914
Abm4_0487	nop10	Abm4_0487	Abm4_1641	GTP-binding protein.	H/ACA RNA-protein complex component Nop10p; Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA.	0.470
Abm4_0487	rpl7ae	Abm4_0487	Abm4_0709	GTP-binding protein.	Ribosomal protein L7Ae Rpl7ae; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.	0.898
Abm4_0487	rps8e	Abm4_0487	Abm4_1147	GTP-binding protein.	Ribosomal protein S8e Rps8e.	0.995
Abm4_0487	rrmJ	Abm4_0487	Abm4_1387	GTP-binding protein.	Ribosomal RNA large subunit methyltransferase J RrmJ; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.	0.933
Abm4_0915	Abm4_0487	Abm4_0915	Abm4_0487	Ribosomal biogenesis protein; Probably involved in the biogenesis of the ribosome.	GTP-binding protein.	0.932