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| | Abm4_0001 | Cdc6 family replication initiation protein Cdc6-1; Involved in regulation of DNA replication. (385 aa) |
| | hisG | ATP phosphoribosyltransferase HisG; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (288 aa) |
| | gatA | Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit A GatA; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). (459 aa) |
| | Abm4_0026 | ABC transporter ATP-binding protein. (365 aa) |
| | Abm4_0027 | ABC transporter permease protein. (387 aa) |
| | minD | Cell division ATPase MinD. (258 aa) |
| | cbiA | Cobyrinic acid a,c-diamide synthase CbiA; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP- dependent amidation of the two carboxylate groups at positions a and c of Ni-sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source. (468 aa) |
| | modE | Molybdate transport system regulatory protein ModE. (230 aa) |
| | thrS | threonyl-tRNA synthetase ThrS; Belongs to the class-II aminoacyl-tRNA synthetase family. (611 aa) |
| | argS | arginyl-tRNA synthetase ArgS; Belongs to the class-I aminoacyl-tRNA synthetase family. (574 aa) |
| | purD | Phosphoribosylamine-glycine ligase PurD; Belongs to the GARS family. (437 aa) |
| | hsdR1 | Type I restriction-modification system R subunit HsdR1. (960 aa) |
| | Abm4_0080 | Universal archaeal protein Kae1; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / TsaD family. (549 aa) |
| | Abm4_0084 | Type III restriction protein restriction subunit. (888 aa) |
| | Abm4_0086 | Hypothetical protein. (396 aa) |
| | Abm4_0087 | Cell wall biosynthesis protein Mur ligase family. (486 aa) |
| | Abm4_0098 | Hef nuclease. (788 aa) |
| | Abm4_0100 | ABC transporter ATP-binding protein. (239 aa) |
| | Abm4_0108 | CRISPR-associated helicase Cas3. (948 aa) |
| | leuS | leucyl-tRNA synthetase LeuS; Belongs to the class-I aminoacyl-tRNA synthetase family. (955 aa) |
| | nadE | NAD+ synthetase NadE; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. (270 aa) |
| | Abm4_0116 | Anion-transporting ATPase. (336 aa) |
| | Abm4_0128 | Copper ion-binding protein. (70 aa) |
| | Abm4_0129 | Copper translocating P-type ATPase. (818 aa) |
| | Abm4_0146 | ABC transporter ATP-binding protein. (260 aa) |
| | nrdD | Anaerobic ribonucleoside-triphosphate reductase NrdD. (772 aa) |
| | lysS | lysyl-tRNA synthetase LysS; Belongs to the class-I aminoacyl-tRNA synthetase family. (528 aa) |
| | glnA | Glutamine synthetase GlnA. (446 aa) |
| | Abm4_0190 | ABC transporter ATP-binding protein. (322 aa) |
| | Abm4_0191 | ABC transporter ATP-binding protein. (204 aa) |
| | Abm4_0193 | Hypothetical protein; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Belongs to the adenylate kinase family. AK6 subfamily. (198 aa) |
| | mptE | Hypothetical protein; Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl- 7,8-dihydropterin diphosphate (6-HMDP); Belongs to the archaeal 6-HMPDK family. (242 aa) |
| | Abm4_0213 | Cdc6 family replication initiation protein Cdc6-2; Involved in regulation of DNA replication. (372 aa) |
| | dnlI | ATP-dependent DNA ligase DnlI; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. (550 aa) |
| | Abm4_0236 | AAA family ATPase CDC48 subfamily. (738 aa) |
| | alaS | alanyl-tRNA synthetase AlaS; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (906 aa) |
| | thiI | Thiamine biosynthesis ATP pyrophosphatase ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (382 aa) |
| | Abm4_0264 | Glycine betaine/L-proline ABC transporter ATP-binding protein. (285 aa) |
| | proV | Glycine betaine/L-proline ABC transporter ATP-binding protein. (279 aa) |
| | radB | DNA repair and recombination protein RadB; Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange. (268 aa) |
| | modC | Molybdate ABC transporter ATP-binding protein ModC. (346 aa) |
| | queC | ExsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. (226 aa) |
| | sucC | succinyl-CoA synthetase beta subunit SucC; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (369 aa) |
| | pgk | Phosphoglycerate kinase Pgk; Belongs to the phosphoglycerate kinase family. (410 aa) |
| | thiM | Hydroxyethylthiazole kinase ThiM; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. (291 aa) |
| | Abm4_0363 | Cation-translocating P-type ATPase. (882 aa) |
| | Abm4_0374 | Hypothetical protein. (425 aa) |
| | Abm4_0377 | Cdc6 family replication initiation protein Cdc6-3. (275 aa) |
| | carA | Carbamoyl-phosphate synthase small subunit CarA; Belongs to the CarA family. (369 aa) |
| | carB | Carbamoylphosphate synthase large subunit CarB; Belongs to the CarB family. (1065 aa) |
| | Abm4_0389 | DEAD/DEAH box helicase domain-containing protein. (725 aa) |
| | tiaS | DNA-binding protein; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA. (405 aa) |
| | ahaE | A1A0 archaeal ATP synthase subunit E AhaE; Produces ATP from ADP in the presence of a proton gradient across the membrane. (207 aa) |
| | ahaC | A1A0 archaeal ATP synthase subunit C AhaC; Produces ATP from ADP in the presence of a proton gradient across the membrane. (384 aa) |
| | ahaF | A1A0 archaeal ATP synthase subunit F AhaF; Produces ATP from ADP in the presence of a proton gradient across the membrane. (104 aa) |
| | ahaA | A1A0 archaeal ATP synthase subunit A AhaA; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family. (584 aa) |
| | ahaB | A1A0 archaeal ATP synthase subunit B AhaB; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit. (461 aa) |
| | ahaD | A1A0 archaeal ATP synthase subunit D AhaD; Produces ATP from ADP in the presence of a proton gradient across the membrane. (226 aa) |
| | Abm4_0433 | ATP-grasp domain-containing protein. (424 aa) |
| | Abm4_0444 | H/ACA RNA-protein complex component Gar1. (93 aa) |
| | pyrH | Uridylate kinase PyrH; Catalyzes the reversible phosphorylation of UMP to UDP. (225 aa) |
| | Abm4_0460 | Cell wall biosynthesis protein Mur ligase family. (480 aa) |
| | nadK | Inositol-1 monophosphatase/fructose-1,6-bisphosphatase/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (613 aa) |
| | Abm4_0476 | ABC transporter ATP-binding protein. (203 aa) |
| | Abm4_0477 | ABC transporter ATP-binding protein. (316 aa) |
| | ribL | FAD synthetase RibL; Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme. (152 aa) |
| | Abm4_0504 | Hypothetical protein. (385 aa) |
| | mptG1 | Beta-ribofuranosylaminobenzene 5'-phosphate synthase MptG1; Catalyzes the condensation of 4-aminobenzoate (pABA) with 5- phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta- ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P). (329 aa) |
| | mptG2 | Beta-ribofuranosylaminobenzene 5'-phosphate synthase MptG2; Catalyzes the condensation of 4-aminobenzoate (pABA) with 5- phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta- ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P). (331 aa) |
| | hsdR2 | Type I restriction-modification system R subunit HsdR2. (912 aa) |
| | hel308 | DEAD/DEAH box helicase domain-containing protein; DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks. (694 aa) |
| | aroK | Shikimate kinase AroK. (286 aa) |
| | Abm4_0546 | UvrD/REP family DNA helicase. (753 aa) |
| | ask | Aspartate kinase Ask; Belongs to the aspartokinase family. (408 aa) |
| | Abm4_0553 | ATPase. (712 aa) |
| | Abm4_0562 | Thermosome subunit; Belongs to the TCP-1 chaperonin family. (539 aa) |
| | Abm4_0571 | Two-component system response regulator. (114 aa) |
| | Abm4_0572 | Response regulator domain-containing protein. (138 aa) |
| | Abm4_0573 | Response regulator/glycosyl transferase GT2 family. (682 aa) |
| | Abm4_0589 | Response regulator/glycosyl transferase GT2 family. (797 aa) |
| | Abm4_0598 | ATP-dependent protease S16 family; Belongs to the peptidase S16 family. (701 aa) |
| | prs | Ribose-phosphate diphosphokinase Prs; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P). (296 aa) |
| | Abm4_0617 | Heavy metal-translocating P-type ATPase. (651 aa) |
| | metG | methionyl-tRNA synthetase MetG; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (671 aa) |
| | cca | tRNA nucleotidyltransferase Cca; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. (461 aa) |
| | coaA | Pantothenate kinase CoaA. (296 aa) |
| | Abm4_0666 | ATPase. (410 aa) |
| | aspS | aspartyl-tRNA synthetase AspS; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn). (439 aa) |
| | cpgS | Cyclic 2,3-diphosphoglycerate synthetase; Catalyzes the formation of cyclic 2,3-diphosphoglycerate (cDPG) by formation of an intramolecular phosphoanhydride bond at the expense of ATP. (456 aa) |
| | Abm4_0701 | Thermosome subunit; Belongs to the TCP-1 chaperonin family. (551 aa) |
| | trpS | tryptophanyl-tRNA synthetase TrpS; Catalyzes the attachment of tryptophan to tRNA(Trp). (363 aa) |
| | ndk | Nucleoside diphosphate kinase Ndk; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. (150 aa) |
| | Abm4_0733 | 4Fe-4S iron sulfur cluster binding protein NifH/frxC family; Belongs to the NifH/BchL/ChlL family. (267 aa) |
| | cbiO | Cobalt ABC transporter ATP-binding protein CbiO; Part of an ABC transporter complex. Responsible for energy coupling to the transport system. (248 aa) |
| | mop | Molybdenum-pterin binding protein Mop. (70 aa) |
| | Abm4_0771 | Nicotinamide-nucleotide adenylyltransferase. (178 aa) |
| | Abm4_0774 | Methyl-coenzyme M reductase component A2-like protein. (574 aa) |
| | rfcS | Replication factor C small subunit RfcS; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcS subfamily. (315 aa) |
| | rfcL | Replication factor C large subunit RfcL; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcL subfamily. (552 aa) |
| | hisS | histidyl-tRNA synthetase HisS; Belongs to the class-II aminoacyl-tRNA synthetase family. (431 aa) |
| | panC | Pantothenate synthase PanC. (245 aa) |
| | pyrG | CTP synthase PyrG; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (546 aa) |
| | parA | Chromosome partitioning ATPase ParA; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (288 aa) |
| | Abm4_0846 | Archaeal ATPase. (388 aa) |
| | uvrA | Excinuclease ABC A subunit UvrA; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (965 aa) |
| | uvrB | Excinuclease ABC B subunit UvrB; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissoc [...] (651 aa) |
| | Abm4_0863 | ATP-dependent DNA helicase UvrD/REP family. (812 aa) |
| | Abm4_0865 | Phosphoenolpyruvate synthase/pyruvate phosphate dikinase. (881 aa) |
| | Abm4_0872 | Cell wall biosynthesis protein Mur ligase family. (526 aa) |
| | Abm4_0873 | Cell wall biosynthesis protein Mur ligase family. (428 aa) |
| | rad50 | DNA double-strand break repair protein Rad50; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex; Belongs to the SMC family. RAD50 subfamily. (925 aa) |
| | Abm4_0892 | Heavy metal-translocating P-type ATPase. (705 aa) |
| | acsA | acetyl-CoA synthetase AcsA. (564 aa) |
| | gatD | glutamyl-tRNA(Gln) amidotransferase subunit D GatD; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate. (435 aa) |
| | gatE | glutamyl-tRNA(Gln) amidotransferase subunit E GatE; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate. (625 aa) |
| | guaA | GMP synthase subunit A GuaA; Catalyzes the synthesis of GMP from XMP. (187 aa) |
| | guaAb | GMP synthase subunit B GuaAb; Catalyzes the synthesis of GMP from XMP. (308 aa) |
| | pan | Proteasome-activating nucleotidase; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase- [...] (414 aa) |
| | Abm4_0981 | Cell wall biosynthesis protein Mur ligase family. (493 aa) |
| | Abm4_0983 | D-alanine-D-alanine ligase. (376 aa) |
| | argB | Acetylglutamate kinase ArgB; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (293 aa) |
| | Abm4_1004 | Archaeal ATPase. (400 aa) |
| | Abm4_1031 | Helicase. (973 aa) |
| | serS | seryl-tRNA synthetase SerS. (425 aa) |
| | purC | Phosphoribosylaminoimidazole-succinocarboxamide synthase PurC; Belongs to the SAICAR synthetase family. (246 aa) |
| | purS | Phosphoribosylformylglycinamidine (FGAM) synthase PurS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought t [...] (90 aa) |
| | purQ | Phosphoribosylformylglycinamidine (FGAM) synthase PurQ; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought t [...] (217 aa) |
| | Abm4_1139 | DEAD/DEAH box helicase domain-containing protein; Belongs to the DEAD box helicase family. (432 aa) |
| | hypE | Hydrogenase expression/formation protein HypE. (336 aa) |
| | pheS | phenylalanyl-tRNA synthetase alpha subunit PheS; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily. (520 aa) |
| | Abm4_1154 | Amino acid ABC transporter ATP-binding protein. (227 aa) |
| | citG | ATP:dephospho-CoA triphosphoribosyl transferase CitG. (302 aa) |
| | acs | ADP-dependent acetyl-CoA synthetase Acs. (698 aa) |
| | cysS | cysteinyl-tRNA synthetase CysS; Belongs to the class-I aminoacyl-tRNA synthetase family. (487 aa) |
| | valS | valyl-tRNA synthetase ValS; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily. (909 aa) |
| | pheT | phenylalanyl-tRNA synthetase subunit beta PheT. (552 aa) |
| | proS | prolyl-tRNA synthetase ProS; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). (469 aa) |
| | btcA | Bicarbonate ABC transporter ATP-binding protein BtcA. (243 aa) |
| | gltX | glutamyl-tRNA synthetase GltX; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (557 aa) |
| | Abm4_1229 | Isopentenyl diphosphate kinase; Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids. (271 aa) |
| | mvk | Mevalonate kinase Mvk; Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)- mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids; Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (413 aa) |
| | cmk | Cytidylate kinase Cmk. (172 aa) |
| | adk | Adenylate kinase Adk; Belongs to the archaeal adenylate kinase family. (185 aa) |
| | pycA | Pyruvate carboxylase subunit A PycA. (495 aa) |
| | coaD | Phosphopantetheine adenylyltransferase CoaD. (151 aa) |
| | pgk2 | 2-phosphoglycerate kinase Pgk2. (303 aa) |
| | Abm4_1312 | Cell wall biosynthesis protein Mur ligase family. (475 aa) |
| | moaB | Molybdenum cofactor biosynthesis protein B MoaB. (174 aa) |
| | glyS | glycyl-tRNA synthetase GlyS. (568 aa) |
| | Abm4_1378 | DEAD/DEAH box helicase domain-containing protein. (867 aa) |
| | purP | 5-formaminoimidazole-4-carboxamide-1-(beta)-D- ribofuranosyl 5'-monophosphate-formate ligase PurP; Catalyzes the ATP- and formate-dependent formylation of 5- aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates. (363 aa) |
| | mcm | Replicative DNA helicase Mcm; Belongs to the MCM family. (666 aa) |
| | tyrS | tyrosyl-tRNA synthetase TyrS; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 3 subfamily. (320 aa) |
| | tmk | Thymidylate kinase Tmk. (197 aa) |
| | mutS2 | DNA mismatch repair ATPase MutS family; Has ATPase and non-specific DNA-binding activities. Belongs to the DNA mismatch repair MutS family. Archaeal Muts2 subfamily. (641 aa) |
| | ubiB | 2-polyprenylphenol 6-hydroxylase UbiB. (546 aa) |
| | Abm4_1426 | ATPase. (282 aa) |
| | ppk | Polyphosphate kinase 1 Ppk; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP); Belongs to the polyphosphate kinase 1 (PPK1) family. (733 aa) |
| | pstB | Phosphate ABC transporter ATP-binding protein PstB; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family. (251 aa) |
| | Abm4_1456 | ATPase RIL. (591 aa) |
| | Abm4_1470 | Serine/threonine protein kinase RIO1 family. (264 aa) |
| | top6B | DNA topoisomerase VI subunit B; Relaxes both positive and negative superturns and exhibits a strong decatenase activity. (598 aa) |
| | top6A | DNA topoisomerase VI subunit A; Relaxes both positive and negative superturns and exhibits a strong decatenase activity; Belongs to the TOP6A family. (371 aa) |
| | Abm4_1480 | ATPase; Belongs to the AAA ATPase family. (375 aa) |
| | atwA | Methyl-coenzyme M reductase component A2 AtwA. (536 aa) |
| | Abm4_1495 | Cell shape determining protein MreB/Mrl family. (357 aa) |
| | ppsA | Phosphoenolpyruvate synthase PpsA; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (760 aa) |
| | sufC | FeS assembly ATPase SufC. (251 aa) |
| | purM | Phosphoribosylformylglycinamidine cyclo-ligase PurM. (340 aa) |
| | argG | Argininosuccinate synthase ArgG; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (391 aa) |
| | nnrE | Carbohydrate kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...] (519 aa) |
| | gatB | Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit B GatB; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily. (450 aa) |
| | hisE | phosphoribosyl-ATP pyrophosphohydrolase HisE. (96 aa) |
| | dnaK | Molecular chaperone DnaK; Acts as a chaperone. (632 aa) |
| | dnaJ | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] (381 aa) |
| | Abm4_1676 | ATP-dependent DNA helicase. (621 aa) |
| | purL | Phosphoribosylformylglycinamidine (FGAM) synthase II PurL; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is though [...] (718 aa) |
| | ileS | isoleucyl-tRNA synthetase IleS; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1107 aa) |
| | metK | S-adenosylmethionine synthetase MetK; Catalyzes the formation of S-adenosylmethionine from methionine and ATP; Belongs to the AdoMet synthase 2 family. (401 aa) |
| | radA | DNA repair and recombination protein RadA; Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules. (311 aa) |
| | thiL | Thiamine monphosphate kinase ThiL; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (344 aa) |
