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rpl12 rpl12 rpl10 rpl10 rpl1 rpl1 rpl11 rpl11 spt5 spt5 tfe tfe Abm4_0249 Abm4_0249 hypC hypC rps3ae rps3ae rtcB rtcB Abm4_0215 Abm4_0215 rplX rplX eif6 eif6 rpl31e rpl31e rpl39e rpl39e rps19e rps19e Abm4_0195 Abm4_0195 rnp4 rnp4 Abm4_0192 Abm4_0192 tbp tbp lysS lysS truD truD leuS leuS Abm4_0099 Abm4_0099 rps15 rps15 Abm4_0080 Abm4_0080 Abm4_0065 Abm4_0065 argS argS Abm4_0051 Abm4_0051 thrS thrS gatA gatA Abm4_1715 Abm4_1715 ileS ileS ksgA ksgA rpoF rpoF rpl21e rpl21e pus10 pus10 csl4 csl4 rpoL rpoL tfs2 tfs2 rpl44e rpl44e rps27e rps27e eif2a eif2a nop10 nop10 Abm4_1639 Abm4_1639 gatB gatB flpA flpA taw2 taw2 trm1 trm1 Abm4_1541 Abm4_1541 Abm4_1503 Abm4_1503 dusA2 dusA2 Abm4_1472 Abm4_1472 eif1a eif1a Abm4_1466 Abm4_1466 ef1b ef1b Abm4_1457 Abm4_1457 Abm4_1456 Abm4_1456 Abm4_1455 Abm4_1455 Abm4_1424 Abm4_1424 Abm4_1419 Abm4_1419 tyrS tyrS eif2b eif2b rrmJ rrmJ rnz rnz dusA1 dusA1 Abm4_1344 Abm4_1344 glyS glyS Abm4_1341 Abm4_1341 Abm4_1316 Abm4_1316 Abm4_1310 Abm4_1310 Abm4_1287 Abm4_1287 rpl3p rpl3p rpl4p rpl4p rpl23 rpl23 rpl2p rpl2p rps19p rps19p rpl22 rpl22 rps3p rps3p rpl29 rpl29 Abm4_1269 Abm4_1269 rnp1 rnp1 rps17 rps17 rpl14 rpl14 rpl24 rpl24 rps4e rps4e rpl5p rpl5p rps14 rps14 rps8p rps8p rpl6p rpl6p Abm4_1259 Abm4_1259 rpl19e rpl19e rpl18 rpl18 rps5p rps5p rpl30 rpl30 rpl15 rpl15 rpl34e rpl34e Abm4_1248 Abm4_1248 cbf5p cbf5p rps13 rps13 rps4p rps4p rps11 rps11 rpoD rpoD rpl18e rpl18e rpl13 rpl13 rps9p rps9p rpoN rpoN rpoK rpoK rps2p rps2p gltX gltX proS proS Abm4_1201 Abm4_1201 pheT pheT valS valS cysS cysS pheS pheS rps8e rps8e hypE hypE serS serS Abm4_1029 Abm4_1029 tfs1 tfs1 tgtA tgtA Abm4_0970 Abm4_0970 Abm4_0968 Abm4_0968 gatE gatE gatD gatD Abm4_0926 Abm4_0926 rnp3 rnp3 rnp2 rnp2 rpl37ae rpl37ae Abm4_0916 Abm4_0916 Abm4_0915 Abm4_0915 Abm4_0914 Abm4_0914 Abm4_0885 Abm4_0885 rpl40e rpl40e Abm4_0848 Abm4_0848 rnc rnc rpl37e rpl37e Abm4_0798 Abm4_0798 Abm4_0797 Abm4_0797 hisS hisS Abm4_0768 Abm4_0768 dhys dhys Abm4_0745 Abm4_0745 rps27ae rps27ae rps24e rps24e rpoE1 rpoE1 eif2g eif2g rps6e rps6e infB infB rpl24e rpl24e rps28e rps28e rpl7ae rpl7ae Abm4_0708 Abm4_0708 trpS trpS endA endA aspS aspS cca cca metG metG Abm4_0629 Abm4_0629 Abm4_0612 Abm4_0612 hypB hypB hypA hypA rps17e rps17e Abm4_0530 Abm4_0530 Abm4_0526 Abm4_0526 Abm4_0525 Abm4_0525 Abm4_0515 Abm4_0515 truA truA eif5a eif5a prf1 prf1 tfb tfb Abm4_0435 Abm4_0435 Abm4_0434 Abm4_0434 tiaS tiaS thgL thgL Abm4_0404 Abm4_0404 rimI rimI rps10 rps10 tuf tuf fusA fusA rps7 rps7 rps12 rps12 nusA nusA rpl30e rpl30e rpoA2 rpoA2 rpoA1 rpoA1 rpoB rpoB rpoH rpoH taw1 taw1 Abm4_0323 Abm4_0323 Abm4_0319 Abm4_0319 hypD hypD gspE gspE Abm4_0269 Abm4_0269 thiI thiI alaS alaS
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
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gene neighborhood
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gene co-occurrence
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textmining
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rpl12Ribosomal protein L12P Rpl12p; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the eukaryotic ribosomal protein P1/P2 family. (100 aa)
rpl10Acidic ribosomal protein P0 RplPO; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (336 aa)
rpl1Ribosomal protein L1P Rpl1p; Binds directly to 23S rRNA. Probably involved in E site tRNA release. (212 aa)
rpl11Ribosomal protein L11P Rpl11p; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family. (161 aa)
spt5Ribosomal protein L24 family; Stimulates transcription elongation; Belongs to the archaeal Spt5 family. (160 aa)
tfeTranscription initiation factor TFIIE alpha subunit Tfe; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabili [...] (151 aa)
Abm4_0249PUA domain-containing protein. (304 aa)
hypCHydrogenase assembly chaperone HypC. (89 aa)
rps3aeRibosomal protein S3Ae Rps3ae; Belongs to the eukaryotic ribosomal protein eS1 family. (191 aa)
rtcBHypothetical protein; Belongs to the RtcB family. (482 aa)
Abm4_0215Hypothetical protein; Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently. (154 aa)
rplXRibosomal protein LX RplX. (74 aa)
eif6Translation initiation factor aIF-6; Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex. (224 aa)
rpl31eRibosomal protein L31e Rpl31e; Belongs to the ribosomal protein L31e family. (88 aa)
rpl39eRibosomal protein L39e Rpl39e; Belongs to the eukaryotic ribosomal protein eL39 family. (51 aa)
rps19eRibosomal protein S19e Rps19e; May be involved in maturation of the 30S ribosomal subunit. Belongs to the eukaryotic ribosomal protein eS19 family. (146 aa)
Abm4_0195RNA-binding protein. (87 aa)
rnp4Ribonuclease P subunit RPR2; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. (123 aa)
Abm4_0192GTP-binding protein. (369 aa)
tbpTATA-box binding protein Tbp; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation. (181 aa)
lysSlysyl-tRNA synthetase LysS; Belongs to the class-I aminoacyl-tRNA synthetase family. (528 aa)
truDtRNA pseudouridine synthase D TruD; Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family. (427 aa)
leuSleucyl-tRNA synthetase LeuS; Belongs to the class-I aminoacyl-tRNA synthetase family. (955 aa)
Abm4_0099tRNA(1-methyladenosine) methyltransferase. (243 aa)
rps15Ribosomal protein S15P Rps15p. (132 aa)
Abm4_0080Universal archaeal protein Kae1; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / TsaD family. (549 aa)
Abm4_0065LSM domain-containing protein. (67 aa)
argSarginyl-tRNA synthetase ArgS; Belongs to the class-I aminoacyl-tRNA synthetase family. (574 aa)
Abm4_0051Signal peptidase I. (140 aa)
thrSthreonyl-tRNA synthetase ThrS; Belongs to the class-II aminoacyl-tRNA synthetase family. (611 aa)
gatAAsp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit A GatA; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). (459 aa)
Abm4_1715Methanogenesis marker protein 11. (310 aa)
ileSisoleucyl-tRNA synthetase IleS; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1107 aa)
ksgADimethyladenosine transferase KsgA; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily. (287 aa)
rpoFDNA-directed RNA polymerase subunit F RpoF. (110 aa)
rpl21eRibosomal protein L21e Rpl21e; Belongs to the eukaryotic ribosomal protein eL21 family. (96 aa)
pus10Pseudouridylate synthase; Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs. (409 aa)
csl4Exosome complex RNA-binding protein Csl4; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs. (189 aa)
rpoLDNA-directed RNA polymerase subunit L RpoL; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoL/eukaryotic RPB11/RPC19 RNA polymerase subunit family. (94 aa)
tfs2Transcription factor S Tfs2; Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (105 aa)
rpl44eRibosomal protein L44e Rpl44e; Binds to the 23S rRNA. (92 aa)
rps27eRibosomal protein S27e Rps27e. (59 aa)
eif2aTranslation initiation factor aIF-2 alpha subunit; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-alpha family. (265 aa)
nop10H/ACA RNA-protein complex component Nop10p; Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA. (53 aa)
Abm4_1639Hypothetical protein. (399 aa)
gatBAsp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit B GatB; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily. (450 aa)
flpAFibrillarin FlpA; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family. (216 aa)
taw2Met-10+ like-protein; S-adenosyl-L-methionine-dependent transferase that acts as a component of the wyosine derivatives biosynthesis pathway. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S- adenosyl-L-methionine to 4-demethylwyosine (imG-14), forming 7- aminocarboxypropyl-demethylwyosine (wybutosine-86) at position 37 of tRNA(Phe). (251 aa)
trm1N2,N2-dimethylguanosine tRNA methyltransferase Trm1; Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. (398 aa)
Abm4_1541PP-loop family protein. (285 aa)
Abm4_1503Ribosomal protein L10e Rpl10e. (160 aa)
dusA2tRNA-dihydrouridine synthase DusA2. (236 aa)
Abm4_1472RNA-binding protein. (199 aa)
eif1aTranslation initiation factor aIF-1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. (104 aa)
Abm4_1466CAAX amino terminal protease family protein. (309 aa)
ef1bTranslation elongation factor aEF-1 beta; Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA. (88 aa)
Abm4_1457peptidyl-tRNA hydrolase. (112 aa)
Abm4_1456ATPase RIL. (591 aa)
Abm4_14554Fe-4S ferredoxin iron-sulfur binding domain-containing protein. (244 aa)
Abm4_1424PP-loop family protein. (310 aa)
Abm4_1419Radical SAM domain-containing protein. (364 aa)
tyrStyrosyl-tRNA synthetase TyrS; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 3 subfamily. (320 aa)
eif2bTranslation initiation factor aIF-2 beta subunit; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-beta/eIF-5 family. (137 aa)
rrmJRibosomal RNA large subunit methyltransferase J RrmJ; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. (202 aa)
rnzRibonuclease Z Rnz; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family. (297 aa)
dusA1tRNA-dihydrouridine synthase DusA1. (329 aa)
Abm4_1344CAAX amino terminal protease family protein. (233 aa)
glySglycyl-tRNA synthetase GlyS. (568 aa)
Abm4_1341RNA methyltransferase TrmH family. (303 aa)
Abm4_1316Met-10+ like-protein. (361 aa)
Abm4_1310Archaeosine tRNA-ribosyltransferase family protein. (249 aa)
Abm4_1287RNA-binding protein. (664 aa)
rpl3pRibosomal protein L3P Rpl3p; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. (336 aa)
rpl4pRibosomal protein L4p Rpl4p; Forms part of the polypeptide exit tunnel. (254 aa)
rpl23Ribosomal protein L23P Rpl23p; Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Belongs to the universal ribosomal protein uL23 family. (86 aa)
rpl2pRibosomal protein L2P Rpl2p; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (241 aa)
rps19pRibosomal protein S19P Rps19p; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (136 aa)
rpl22Ribosomal protein L22P Rpl22p; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome. (154 aa)
rps3pRibosomal protein S3P Rps3p; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family. (254 aa)
rpl29Ribosomal protein L29P Rpl29p; Belongs to the universal ribosomal protein uL29 family. (68 aa)
Abm4_1269Translation initiation factor aSUI1; Belongs to the SUI1 family. (115 aa)
rnp1Ribonuclease P subunit P29; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends; Belongs to the eukaryotic/archaeal RNase P protein component 1 family. (93 aa)
rps17Ribosomal protein S17P Rps17p; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (105 aa)
rpl14Ribosomal protein L14P Rpl14p; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (132 aa)
rpl24Ribosomal protein L24P Rpl24p; Located at the polypeptide exit tunnel on the outside of the subunit. (116 aa)
rps4eRibosomal protein S4e Rps4e; Belongs to the eukaryotic ribosomal protein eS4 family. (241 aa)
rpl5pRibosomal protein L5P Rpl5p; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (171 aa)
rps14Ribosomal protein S14P Rps14p; Binds 16S rRNA, required for the assembly of 30S particles. (47 aa)
rps8pRibosomal protein S8P Rps8p; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (130 aa)
rpl6pRibosomal protein L6P Rpl6p; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (178 aa)
Abm4_1259Ribosomal protein L32e Rpl32e. (108 aa)
rpl19eRibosomal protein L19e Rpl19e; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family. (149 aa)
rpl18Ribosomal protein L18P Rpl18p; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (193 aa)
rps5pRibosomal protein S5P Rps5p; With S4 and S12 plays an important role in translational accuracy. (214 aa)
rpl30Ribosomal protein L30P Rpl30p. (152 aa)
rpl15Ribosomal protein L15P Rpl15p; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (145 aa)
rpl34eRibosomal protein L34e Rpl34e; Belongs to the eukaryotic ribosomal protein eL34 family. (88 aa)
Abm4_1248Ribosomal protein L14e Rpl14e. (73 aa)
cbf5pH/ACA RNA-protein complex component Cbf5p; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily. (320 aa)
rps13Ribosomal protein S13P Rps13p; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement; Belongs to the universal ribosomal protein uS13 family. (153 aa)
rps4pRibosomal protein S4P Rps4p; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (180 aa)
rps11Ribosomal protein S11P Rps11p; Located on the platform of the 30S subunit. Belongs to the universal ribosomal protein uS11 family. (130 aa)
rpoDDNA-directed RNA polymerase subunit D RpoD; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (267 aa)
rpl18eRibosomal protein L18e Rpl18e; Belongs to the eukaryotic ribosomal protein eL18 family. (121 aa)
rpl13Ribosomal protein L13P Rpl13p; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (140 aa)
rps9pRibosomal protein S9P Rps9p; Belongs to the universal ribosomal protein uS9 family. (132 aa)
rpoNDNA-directed RNA polymerase subunit N RpoN. (56 aa)
rpoKDNA-directed RNA polymerase subunit K RpoK; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit family. (60 aa)
rps2pRibosomal protein S2P Rps2p; Belongs to the universal ribosomal protein uS2 family. (200 aa)
gltXglutamyl-tRNA synthetase GltX; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (557 aa)
proSprolyl-tRNA synthetase ProS; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). (469 aa)
Abm4_12014Fe-4S ferredoxin iron-sulfur binding domain-containing protein. (241 aa)
pheTphenylalanyl-tRNA synthetase subunit beta PheT. (552 aa)
valSvalyl-tRNA synthetase ValS; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily. (909 aa)
cysScysteinyl-tRNA synthetase CysS; Belongs to the class-I aminoacyl-tRNA synthetase family. (487 aa)
pheSphenylalanyl-tRNA synthetase alpha subunit PheS; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily. (520 aa)
rps8eRibosomal protein S8e Rps8e. (125 aa)
hypEHydrogenase expression/formation protein HypE. (336 aa)
serSseryl-tRNA synthetase SerS. (425 aa)
Abm4_1029Hypothetical protein. (408 aa)
tfs1Transcription factor S Tfs1; Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (106 aa)
tgtAArchaeosine tRNA-ribosyltransferase TgtA; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family. (659 aa)
Abm4_0970RNA methylase. (343 aa)
Abm4_0968Hypothetical protein. (169 aa)
gatEglutamyl-tRNA(Gln) amidotransferase subunit E GatE; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate. (625 aa)
gatDglutamyl-tRNA(Gln) amidotransferase subunit D GatD; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate. (435 aa)
Abm4_0926Ribosomal protein L15e Rpl15e. (184 aa)
rnp3Ribonuclease P subunit P30; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends; Belongs to the eukaryotic/archaeal RNase P protein component 3 family. (244 aa)
rnp2Ribonuclease P subunit P14; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends; Belongs to the eukaryotic/archaeal RNase P protein component 2 family. (120 aa)
rpl37aeRibosomal protein L37Ae Rpl37ae; Binds to the 23S rRNA. (87 aa)
Abm4_0916DNA-directed RNA polymerase subunit P RpoP. (43 aa)
Abm4_0915Ribosomal biogenesis protein; Probably involved in the biogenesis of the ribosome. (171 aa)
Abm4_0914Hypothetical protein. (89 aa)
Abm4_0885Hypothetical protein; Probable pre-rRNA processing protein involved in ribosome biogenesis; Belongs to the TSR3 family. (172 aa)
rpl40eRibosomal protein L40e Rpl40e; Belongs to the eukaryotic ribosomal protein eL40 family. (48 aa)
Abm4_0848Archaeal histone. (67 aa)
rncRibonuclease III Rnc. (222 aa)
rpl37eRibosomal protein L37e Rpl37e; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL37 family. (61 aa)
Abm4_0798LSM domain-containing protein; Belongs to the snRNP Sm proteins family. (77 aa)
Abm4_0797RNA-binding protein. (159 aa)
hisShistidyl-tRNA synthetase HisS; Belongs to the class-II aminoacyl-tRNA synthetase family. (431 aa)
Abm4_0768Hypothetical protein. (164 aa)
dhysDeoxyhypusine synthase Dhys. (344 aa)
Abm4_0745Hypothetical protein. (586 aa)
rps27aeRibosomal protein S27ae Rps27ae; Belongs to the eukaryotic ribosomal protein eS31 family. (51 aa)
rps24eRibosomal protein S24e Rps24e; Belongs to the eukaryotic ribosomal protein eS24 family. (103 aa)
rpoE1DNA-directed RNA polymerase subunit E' RpoE1. (185 aa)
eif2gTranslation initiation factor aIF-2 gamma subunit; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily. (410 aa)
rps6eRibosomal protein S6e Rps6e; Belongs to the eukaryotic ribosomal protein eS6 family. (126 aa)
infBTranslation initiation factor IF-2; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2. (595 aa)
rpl24eRibosomal protein L24e Rpl24e; Binds to the 23S rRNA. (53 aa)
rps28eRibosomal protein S28e Rps28e; Belongs to the eukaryotic ribosomal protein eS28 family. (68 aa)
rpl7aeRibosomal protein L7Ae Rpl7ae; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs. (123 aa)
Abm4_0708Archaeal histone. (67 aa)
trpStryptophanyl-tRNA synthetase TrpS; Catalyzes the attachment of tryptophan to tRNA(Trp). (363 aa)
endAtRNA intron endonuclease EndA. (171 aa)
aspSaspartyl-tRNA synthetase AspS; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn). (439 aa)
ccatRNA nucleotidyltransferase Cca; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. (461 aa)
metGmethionyl-tRNA synthetase MetG; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (671 aa)
Abm4_0629Hypothetical protein. (278 aa)
Abm4_0612Hypothetical protein. (136 aa)
hypBHydrogenase accessory protein HypB. (220 aa)
hypAHydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. (124 aa)
rps17eRibosomal protein S17e Rps17e; Belongs to the eukaryotic ribosomal protein eS17 family. (64 aa)
Abm4_0530Histone acetyltransferase ELP3 family. (570 aa)
Abm4_0526Archaeal histone. (66 aa)
Abm4_0525MiaB-like tRNA modifying enzyme. (429 aa)
Abm4_0515Hypothetical protein. (211 aa)
truAtRNA pseudouridine synthase A TruA; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs; Belongs to the tRNA pseudouridine synthase TruA family. (296 aa)
eif5aTranslation initiation factor eIF-5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family. (135 aa)
prf1Peptide chain release factor aRF1; Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. (411 aa)
tfbTranscription initiation factor TFIIB Tfb; Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB). (310 aa)
Abm4_0435Hypothetical protein. (134 aa)
Abm4_04344Fe-4S ferredoxin iron-sulfur binding domain-containing protein. (267 aa)
tiaSDNA-binding protein; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA. (405 aa)
thgLtRNA(His) guanylyltransferase ThgL. (282 aa)
Abm4_0404tRNA binding domain-containing protein. (241 aa)
rimIRibosomal-protein-alanine acetyltransferase RimI. (149 aa)
rps10Ribosomal protein S10P Rps10p; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (102 aa)
tufTranslation elongation factor aEF-1 alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. (413 aa)
fusATranslation elongation factor aEF-2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF [...] (730 aa)
rps7Ribosomal protein S7P Rps7p; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center; Belongs to the universal ribosomal protein uS7 family. (187 aa)
rps12Ribosomal protein S12P Rps12p; With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family. (141 aa)
nusATranscription elongation factor NusA-like protein; Participates in transcription termination. Belongs to the NusA family. (143 aa)
rpl30eRibosomal protein L30e Rpl30e; Belongs to the eukaryotic ribosomal protein eL30 family. (99 aa)
rpoA2DNA-directed RNA polymerase subunit A'' RpoA2; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (423 aa)
rpoA1DNA-directed RNA polymerase subunit A' RpoA1; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (869 aa)
rpoBDNA-directed RNA polymerase subunit B RpoB; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1117 aa)
rpoHDNA-directed RNA polymerase subunit H RpoH; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family. (81 aa)
taw1tRNA-modifying enzyme; Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe). (306 aa)
Abm4_0323Hypothetical protein; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. (181 aa)
Abm4_0319Hypothetical protein; Belongs to the LarC family. (406 aa)
hypDHydrogenase expression/formation protein HypD. (348 aa)
gspEType II secretion system protein E GspE. (608 aa)
Abm4_0269Sua5/YciO/YrdC/YwlC family translation factor. (196 aa)
thiIThiamine biosynthesis ATP pyrophosphatase ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (382 aa)
alaSalanyl-tRNA synthetase AlaS; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (906 aa)
Your Current Organism:
Methanobrevibacter sp. AbM4
NCBI taxonomy Id: 224719
Other names: M. sp. AbM4
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