(9 nodes) Large ribosomal subunit network (Methanobrevibacter sp. AbM4)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	rpl22	Ribosomal protein L22P Rpl22p; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome. (154 aa)
	rpl1	Ribosomal protein L1P Rpl1p; Binds directly to 23S rRNA. Probably involved in E site tRNA release. (212 aa)
	rpl30e	Ribosomal protein L30e Rpl30e; Belongs to the eukaryotic ribosomal protein eL30 family. (99 aa)
	rpl13	Ribosomal protein L13P Rpl13p; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (140 aa)
	rpl15	Ribosomal protein L15P Rpl15p; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (145 aa)
	rpl30	Ribosomal protein L30P Rpl30p. (152 aa)
	rpl19e	Ribosomal protein L19e Rpl19e; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family. (149 aa)
	rpl24	Ribosomal protein L24P Rpl24p; Located at the polypeptide exit tunnel on the outside of the subunit. (116 aa)
	rpl2p	Ribosomal protein L2P Rpl2p; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (241 aa)

Your Current Organism:

Methanobrevibacter sp. AbM4

NCBI taxonomy Id: 224719
Other names: M. sp. AbM4

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
rpl1	rpl13	Abm4_0257	Abm4_1238	Ribosomal protein L1P Rpl1p; Binds directly to 23S rRNA. Probably involved in E site tRNA release.	Ribosomal protein L13P Rpl13p; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	0.999
rpl1	rpl15	Abm4_0257	Abm4_1254	Ribosomal protein L1P Rpl1p; Binds directly to 23S rRNA. Probably involved in E site tRNA release.	Ribosomal protein L15P Rpl15p; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.	0.999
rpl1	rpl19e	Abm4_0257	Abm4_1258	Ribosomal protein L1P Rpl1p; Binds directly to 23S rRNA. Probably involved in E site tRNA release.	Ribosomal protein L19e Rpl19e; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family.	0.999
rpl1	rpl22	Abm4_0257	Abm4_1272	Ribosomal protein L1P Rpl1p; Binds directly to 23S rRNA. Probably involved in E site tRNA release.	Ribosomal protein L22P Rpl22p; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.	0.999
rpl1	rpl24	Abm4_0257	Abm4_1265	Ribosomal protein L1P Rpl1p; Binds directly to 23S rRNA. Probably involved in E site tRNA release.	Ribosomal protein L24P Rpl24p; Located at the polypeptide exit tunnel on the outside of the subunit.	0.999
rpl1	rpl2p	Abm4_0257	Abm4_1274	Ribosomal protein L1P Rpl1p; Binds directly to 23S rRNA. Probably involved in E site tRNA release.	Ribosomal protein L2P Rpl2p; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	0.999
rpl1	rpl30	Abm4_0257	Abm4_1255	Ribosomal protein L1P Rpl1p; Binds directly to 23S rRNA. Probably involved in E site tRNA release.	Ribosomal protein L30P Rpl30p.	0.999
rpl1	rpl30e	Abm4_0257	Abm4_0350	Ribosomal protein L1P Rpl1p; Binds directly to 23S rRNA. Probably involved in E site tRNA release.	Ribosomal protein L30e Rpl30e; Belongs to the eukaryotic ribosomal protein eL30 family.	0.999
rpl13	rpl1	Abm4_1238	Abm4_0257	Ribosomal protein L13P Rpl13p; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	Ribosomal protein L1P Rpl1p; Binds directly to 23S rRNA. Probably involved in E site tRNA release.	0.999
rpl13	rpl15	Abm4_1238	Abm4_1254	Ribosomal protein L13P Rpl13p; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	Ribosomal protein L15P Rpl15p; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.	0.999
rpl13	rpl19e	Abm4_1238	Abm4_1258	Ribosomal protein L13P Rpl13p; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	Ribosomal protein L19e Rpl19e; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family.	0.999
rpl13	rpl22	Abm4_1238	Abm4_1272	Ribosomal protein L13P Rpl13p; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	Ribosomal protein L22P Rpl22p; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.	0.999
rpl13	rpl24	Abm4_1238	Abm4_1265	Ribosomal protein L13P Rpl13p; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	Ribosomal protein L24P Rpl24p; Located at the polypeptide exit tunnel on the outside of the subunit.	0.999
rpl13	rpl2p	Abm4_1238	Abm4_1274	Ribosomal protein L13P Rpl13p; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	Ribosomal protein L2P Rpl2p; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	0.999
rpl13	rpl30	Abm4_1238	Abm4_1255	Ribosomal protein L13P Rpl13p; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	Ribosomal protein L30P Rpl30p.	0.999
rpl13	rpl30e	Abm4_1238	Abm4_0350	Ribosomal protein L13P Rpl13p; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	Ribosomal protein L30e Rpl30e; Belongs to the eukaryotic ribosomal protein eL30 family.	0.998
rpl15	rpl1	Abm4_1254	Abm4_0257	Ribosomal protein L15P Rpl15p; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.	Ribosomal protein L1P Rpl1p; Binds directly to 23S rRNA. Probably involved in E site tRNA release.	0.999
rpl15	rpl13	Abm4_1254	Abm4_1238	Ribosomal protein L15P Rpl15p; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.	Ribosomal protein L13P Rpl13p; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	0.999
rpl15	rpl19e	Abm4_1254	Abm4_1258	Ribosomal protein L15P Rpl15p; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.	Ribosomal protein L19e Rpl19e; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family.	0.999
rpl15	rpl22	Abm4_1254	Abm4_1272	Ribosomal protein L15P Rpl15p; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.	Ribosomal protein L22P Rpl22p; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.	0.999