STRINGSTRING
rpl23 rpl23 rpl2p rpl2p rps19p rps19p rpl22 rpl22 rps3p rps3p rpl29 rpl29 Abm4_1269 Abm4_1269 rps17 rps17 rpl14 rpl14 rpl24 rpl24 rps4e rps4e rpl5p rpl5p rps14 rps14 rps8p rps8p rpl6p rpl6p Abm4_1259 Abm4_1259 rpl19e rpl19e rpl18 rpl18 rps5p rps5p rpl30 rpl30 rpl15 rpl15 rpl34e rpl34e Abm4_1248 Abm4_1248 rps13 rps13 rps4p rps4p rps11 rps11 rpl18e rpl18e rpl13 rpl13 rps9p rps9p rps2p rps2p rnj rnj gltX gltX proS proS Abm4_1200 Abm4_1200 pheT pheT valS valS nth nth cysS cysS Abm4_1176 Abm4_1176 Abm4_1167 Abm4_1167 pheS pheS xth xth polB2 polB2 rps8e rps8e Abm4_1121 Abm4_1121 serS serS Abm4_1111 Abm4_1111 Abm4_1090 Abm4_1090 Abm4_1088 Abm4_1088 cas2-2 cas2-2 Abm4_0987 Abm4_0987 Abm4_1004 Abm4_1004 Abm4_1017 Abm4_1017 Abm4_1018 Abm4_1018 Abm4_1029 Abm4_1029 Abm4_1030 Abm4_1030 Abm4_1041 Abm4_1041 Abm4_1045 Abm4_1045 glf glf Abm4_1065 Abm4_1065 hsdR1 hsdR1 hsdS1 hsdS1 hsdM1 hsdM1 Abm4_0068 Abm4_0068 argS argS thrS thrS Abm4_0035 Abm4_0035 Abm4_0031 Abm4_0031 Abm4_0023 Abm4_0023 gatA gatA Abm4_0001 Abm4_0001 rps15 rps15 Abm4_0085 Abm4_0085 Abm4_0096 Abm4_0096 Abm4_0098 Abm4_0098 cas2 cas2 Abm4_0099 Abm4_0099 cas1 cas1 Abm4_0110 Abm4_0110 leuS leuS cbiE cbiE polD2 polD2 nrdD nrdD lysS lysS fen fen Abm4_0186 Abm4_0186 Abm4_0192 Abm4_0192 rps19e rps19e rpl39e rpl39e rpl31e rpl31e eif6 eif6 rplX rplX Abm4_0213 Abm4_0213 rps3ae rps3ae dnlI dnlI pelA pelA Abm4_0250 Abm4_0250 spt5 spt5 rpl11 rpl11 rpl1 rpl1 rpl10 rpl10 rpl12 rpl12 alaS alaS radB radB Abm4_0292 Abm4_0292 Abm4_0304 Abm4_0304 Abm4_0323 Abm4_0323 rpl30e rpl30e rps12 rps12 rps7 rps7 fusA fusA tuf tuf rps10 rps10 Abm4_0377 Abm4_0377 Abm4_0387 Abm4_0387 Abm4_0389 Abm4_0389 Abm4_0404 Abm4_0404 ahaH ahaH dnaG dnaG xerC xerC prf1 prf1 eif5a eif5a Abm4_0485 Abm4_0485 Abm4_0515 Abm4_0515 hsdR2 hsdR2 hsdM2 hsdM2 hsdS3 hsdS3 hsdS4 hsdS4 Abm4_0523 Abm4_0523 hsdS5 hsdS5 hel308 hel308 Abm4_0537 Abm4_0537 rps17e rps17e Abm4_0546 Abm4_0546 Abm4_0606 Abm4_0606 Abm4_0622 Abm4_0622 Abm4_0641 Abm4_0641 metG metG priB priB priA priA Abm4_0659 Abm4_0659 Abm4_0675 Abm4_0675 aspS aspS trpS trpS rpl7ae rpl7ae rps28e rps28e rpl24e rpl24e infB infB rps6e rps6e eif2g eif2g rps24e rps24e rps27ae rps27ae Abm4_0725 Abm4_0725 Abm4_0756 Abm4_0756 cbiT cbiT Abm4_0768 Abm4_0768 rfcS rfcS rfcL rfcL hisS hisS Abm4_0786 Abm4_0786 Abm4_0797 Abm4_0797 rpl37e rpl37e uvrC uvrC ogt ogt Abm4_0839 Abm4_0839 Abm4_0846 Abm4_0846 uvrA uvrA uvrB uvrB Abm4_0863 Abm4_0863 Abm4_0865 Abm4_0865 rad50 rad50 mre11 mre11 Abm4_0882 Abm4_0882 rpl40e rpl40e rpl37ae rpl37ae rrp42 rrp42 rrp41 rrp41 rrp4 rrp4 psmA psmA Abm4_0926 Abm4_0926 gatD gatD gatE gatE Abm4_0966 Abm4_0966 Abm4_0970 Abm4_0970 Abm4_0982 Abm4_0982 cas1-2 cas1-2 polB polB Abm4_1716 Abm4_1716 rfbD rfbD rfbA rfbA rfbC rfbC Abm4_1699 Abm4_1699 Abm4_1697 Abm4_1697 Abm4_1696 Abm4_1696 rpaI rpaI radA radA ileS ileS ogg ogg ksgA ksgA rpl21e rpl21e csl4 csl4 Abm4_1650 Abm4_1650 pcn pcn rpl44e rpl44e rps27e rps27e eif2a eif2a dnaJ dnaJ gatB gatB hjc hjc polB1 polB1 trm1 trm1 Abm4_1503 Abm4_1503 rnhB rnhB Abm4_1479 Abm4_1479 top6A top6A top6B top6B eif1a eif1a ef1b ef1b Abm4_1457 Abm4_1457 Abm4_1456 Abm4_1456 Abm4_1418 Abm4_1418 mutS2 mutS2 xseB xseB xseA xseA tyrS tyrS eif2b eif2b mcm mcm rrmJ rrmJ Abm4_1378 Abm4_1378 nucS nucS glyS glyS Abm4_1341 Abm4_1341 Abm4_1287 Abm4_1287 rpl3p rpl3p rpl4p rpl4p
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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rpl23Ribosomal protein L23P Rpl23p; Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Belongs to the universal ribosomal protein uL23 family. (86 aa)
rpl2pRibosomal protein L2P Rpl2p; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (241 aa)
rps19pRibosomal protein S19P Rps19p; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (136 aa)
rpl22Ribosomal protein L22P Rpl22p; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome. (154 aa)
rps3pRibosomal protein S3P Rps3p; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family. (254 aa)
rpl29Ribosomal protein L29P Rpl29p; Belongs to the universal ribosomal protein uL29 family. (68 aa)
Abm4_1269Translation initiation factor aSUI1; Belongs to the SUI1 family. (115 aa)
rps17Ribosomal protein S17P Rps17p; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (105 aa)
rpl14Ribosomal protein L14P Rpl14p; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (132 aa)
rpl24Ribosomal protein L24P Rpl24p; Located at the polypeptide exit tunnel on the outside of the subunit. (116 aa)
rps4eRibosomal protein S4e Rps4e; Belongs to the eukaryotic ribosomal protein eS4 family. (241 aa)
rpl5pRibosomal protein L5P Rpl5p; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (171 aa)
rps14Ribosomal protein S14P Rps14p; Binds 16S rRNA, required for the assembly of 30S particles. (47 aa)
rps8pRibosomal protein S8P Rps8p; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (130 aa)
rpl6pRibosomal protein L6P Rpl6p; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (178 aa)
Abm4_1259Ribosomal protein L32e Rpl32e. (108 aa)
rpl19eRibosomal protein L19e Rpl19e; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family. (149 aa)
rpl18Ribosomal protein L18P Rpl18p; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (193 aa)
rps5pRibosomal protein S5P Rps5p; With S4 and S12 plays an important role in translational accuracy. (214 aa)
rpl30Ribosomal protein L30P Rpl30p. (152 aa)
rpl15Ribosomal protein L15P Rpl15p; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (145 aa)
rpl34eRibosomal protein L34e Rpl34e; Belongs to the eukaryotic ribosomal protein eL34 family. (88 aa)
Abm4_1248Ribosomal protein L14e Rpl14e. (73 aa)
rps13Ribosomal protein S13P Rps13p; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement; Belongs to the universal ribosomal protein uS13 family. (153 aa)
rps4pRibosomal protein S4P Rps4p; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (180 aa)
rps11Ribosomal protein S11P Rps11p; Located on the platform of the 30S subunit. Belongs to the universal ribosomal protein uS11 family. (130 aa)
rpl18eRibosomal protein L18e Rpl18e; Belongs to the eukaryotic ribosomal protein eL18 family. (121 aa)
rpl13Ribosomal protein L13P Rpl13p; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (140 aa)
rps9pRibosomal protein S9P Rps9p; Belongs to the universal ribosomal protein uS9 family. (132 aa)
rps2pRibosomal protein S2P Rps2p; Belongs to the universal ribosomal protein uS2 family. (200 aa)
rnjRNA-metabolising metallo-beta-lactamase; An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation; Belongs to the metallo-beta-lactamase superfamily. RNA- metabolizing metallo-beta-lactamase-like family. Archaeal RNase J subfamily. (451 aa)
gltXglutamyl-tRNA synthetase GltX; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (557 aa)
proSprolyl-tRNA synthetase ProS; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). (469 aa)
Abm4_1200Adhesin-like protein. (600 aa)
pheTphenylalanyl-tRNA synthetase subunit beta PheT. (552 aa)
valSvalyl-tRNA synthetase ValS; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily. (909 aa)
nthEndonuclease III Nth; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (215 aa)
cysScysteinyl-tRNA synthetase CysS; Belongs to the class-I aminoacyl-tRNA synthetase family. (487 aa)
Abm4_1176Endonuclease III-related protein. (243 aa)
Abm4_1167DNA-3-methyladenine glycosylase I. (189 aa)
pheSphenylalanyl-tRNA synthetase alpha subunit PheS; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily. (520 aa)
xthExodeoxyribonuclease III Xth. (257 aa)
polB2DNA polymerase family B PolB2. (236 aa)
rps8eRibosomal protein S8e Rps8e. (125 aa)
Abm4_1121Hypothetical protein. (233 aa)
serSseryl-tRNA synthetase SerS. (425 aa)
Abm4_1111Restriction enzyme modulator protein. (340 aa)
Abm4_1090Hypothetical protein. (287 aa)
Abm4_1088Acyltransferase. (386 aa)
cas2-2CRISPR-associated endoribonuclease Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (91 aa)
Abm4_0987RNA methylase. (269 aa)
Abm4_1004Archaeal ATPase. (400 aa)
Abm4_1017Type II restriction endonuclease; Recognizes the double-stranded unmethylated sequence GATC and cleaves before G-1; Belongs to the type II restriction enzyme DpnII family. (295 aa)
Abm4_1018Type II DNA modification methylase. (309 aa)
Abm4_1029Hypothetical protein. (408 aa)
Abm4_1030Hydrolase HAD superfamily. (214 aa)
Abm4_1041Hydrolase HAD superfamily. (204 aa)
Abm4_1045Hydrolase HAD superfamily. (212 aa)
glfUDP-galactopyranose mutase Glf. (366 aa)
Abm4_1065Radical SAM domain-containing protein. (298 aa)
hsdR1Type I restriction-modification system R subunit HsdR1. (960 aa)
hsdS1Type I restriction-modification system S subunit HsdS1. (411 aa)
hsdM1Type I restriction-modification system M subunit HsdM1. (669 aa)
Abm4_0068Type II restriction endonuclease. (360 aa)
argSarginyl-tRNA synthetase ArgS; Belongs to the class-I aminoacyl-tRNA synthetase family. (574 aa)
thrSthreonyl-tRNA synthetase ThrS; Belongs to the class-II aminoacyl-tRNA synthetase family. (611 aa)
Abm4_0035Radical SAM domain-containing protein. (371 aa)
Abm4_0031PHP domain-containing protein. (219 aa)
Abm4_0023Xylose isomerase-like TIM barrel domain-containing protein. (250 aa)
gatAAsp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit A GatA; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). (459 aa)
Abm4_0001Cdc6 family replication initiation protein Cdc6-1; Involved in regulation of DNA replication. (385 aa)
rps15Ribosomal protein S15P Rps15p. (132 aa)
Abm4_0085Site-specific DNA-methyltransferase. (277 aa)
Abm4_0096Type II DNA modification methylase. (375 aa)
Abm4_0098Hef nuclease. (788 aa)
cas2CRISPR-associated endoribonuclease Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (87 aa)
Abm4_0099tRNA(1-methyladenosine) methyltransferase. (243 aa)
cas1CRISPR-associated endonuclease Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (322 aa)
Abm4_0110CRISPR-associated protein Cas7. (323 aa)
leuSleucyl-tRNA synthetase LeuS; Belongs to the class-I aminoacyl-tRNA synthetase family. (955 aa)
cbiEPrecorrin-6y C5,15-methyltransferase (decarboxylating) CbiE. (213 aa)
polD2DNA polymerase large subunit DP2 PolD2; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase. (1121 aa)
nrdDAnaerobic ribonucleoside-triphosphate reductase NrdD. (772 aa)
lysSlysyl-tRNA synthetase LysS; Belongs to the class-I aminoacyl-tRNA synthetase family. (528 aa)
fenFlap endonuclease Fen; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. [...] (327 aa)
Abm4_0186Oligosaccharyl transferase. (906 aa)
Abm4_0192GTP-binding protein. (369 aa)
rps19eRibosomal protein S19e Rps19e; May be involved in maturation of the 30S ribosomal subunit. Belongs to the eukaryotic ribosomal protein eS19 family. (146 aa)
rpl39eRibosomal protein L39e Rpl39e; Belongs to the eukaryotic ribosomal protein eL39 family. (51 aa)
rpl31eRibosomal protein L31e Rpl31e; Belongs to the ribosomal protein L31e family. (88 aa)
eif6Translation initiation factor aIF-6; Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex. (224 aa)
rplXRibosomal protein LX RplX. (74 aa)
Abm4_0213Cdc6 family replication initiation protein Cdc6-2; Involved in regulation of DNA replication. (372 aa)
rps3aeRibosomal protein S3Ae Rps3ae; Belongs to the eukaryotic ribosomal protein eS1 family. (191 aa)
dnlIATP-dependent DNA ligase DnlI; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. (550 aa)
pelACell division protein pelota PelA; May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity. (353 aa)
Abm4_0250HD domain-containing protein. (164 aa)
spt5Ribosomal protein L24 family; Stimulates transcription elongation; Belongs to the archaeal Spt5 family. (160 aa)
rpl11Ribosomal protein L11P Rpl11p; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family. (161 aa)
rpl1Ribosomal protein L1P Rpl1p; Binds directly to 23S rRNA. Probably involved in E site tRNA release. (212 aa)
rpl10Acidic ribosomal protein P0 RplPO; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (336 aa)
rpl12Ribosomal protein L12P Rpl12p; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the eukaryotic ribosomal protein P1/P2 family. (100 aa)
alaSalanyl-tRNA synthetase AlaS; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (906 aa)
radBDNA repair and recombination protein RadB; Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange. (268 aa)
Abm4_0292Sialyltransferase. (482 aa)
Abm4_0304Glycosyl transferase GT4 family. (396 aa)
Abm4_0323Hypothetical protein; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. (181 aa)
rpl30eRibosomal protein L30e Rpl30e; Belongs to the eukaryotic ribosomal protein eL30 family. (99 aa)
rps12Ribosomal protein S12P Rps12p; With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family. (141 aa)
rps7Ribosomal protein S7P Rps7p; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center; Belongs to the universal ribosomal protein uS7 family. (187 aa)
fusATranslation elongation factor aEF-2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF [...] (730 aa)
tufTranslation elongation factor aEF-1 alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. (413 aa)
rps10Ribosomal protein S10P Rps10p; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (102 aa)
Abm4_0377Cdc6 family replication initiation protein Cdc6-3. (275 aa)
Abm4_0387Hypothetical protein. (246 aa)
Abm4_0389DEAD/DEAH box helicase domain-containing protein. (725 aa)
Abm4_0404tRNA binding domain-containing protein. (241 aa)
ahaHA1A0 archaeal ATP synthase subunit H AhaH. (104 aa)
dnaGDNA primase DnaG; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. (427 aa)
xerCTyrosine recombinase XerC; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Belongs to the 'phage' integrase family. XerA subfamily. (330 aa)
prf1Peptide chain release factor aRF1; Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. (411 aa)
eif5aTranslation initiation factor eIF-5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family. (135 aa)
Abm4_0485Transposase. (206 aa)
Abm4_0515Hypothetical protein. (211 aa)
hsdR2Type I restriction-modification system R subunit HsdR2. (912 aa)
hsdM2Type I restriction-modification system M subunit HsdM2. (511 aa)
hsdS3Type I restriction-modification system S subunit HsdS3. (387 aa)
hsdS4Type I restriction-modification system S subunit HsdS4. (115 aa)
Abm4_0523Phage integrase family protein. (347 aa)
hsdS5Type I restriction-modification system S subunit HsdS5. (340 aa)
hel308DEAD/DEAH box helicase domain-containing protein; DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks. (694 aa)
Abm4_0537Glycosyl transferase GT4 family. (363 aa)
rps17eRibosomal protein S17e Rps17e; Belongs to the eukaryotic ribosomal protein eS17 family. (64 aa)
Abm4_0546UvrD/REP family DNA helicase. (753 aa)
Abm4_0606Acyltransferase. (359 aa)
Abm4_0622Cell wall biosynthesis protein phospho-N-acetylmuramoyl-pentapeptide-transferase family. (338 aa)
Abm4_0641Hypothetical protein. (161 aa)
metGmethionyl-tRNA synthetase MetG; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (671 aa)
priBDNA primase large subunit PriB; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair. (452 aa)
priADNA primase small subunit PriA; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthe [...] (334 aa)
Abm4_0659PHP domain-containing protein. (220 aa)
Abm4_0675Hydrolase TatD family. (253 aa)
aspSaspartyl-tRNA synthetase AspS; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn). (439 aa)
trpStryptophanyl-tRNA synthetase TrpS; Catalyzes the attachment of tryptophan to tRNA(Trp). (363 aa)
rpl7aeRibosomal protein L7Ae Rpl7ae; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs. (123 aa)
rps28eRibosomal protein S28e Rps28e; Belongs to the eukaryotic ribosomal protein eS28 family. (68 aa)
rpl24eRibosomal protein L24e Rpl24e; Binds to the 23S rRNA. (53 aa)
infBTranslation initiation factor IF-2; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2. (595 aa)
rps6eRibosomal protein S6e Rps6e; Belongs to the eukaryotic ribosomal protein eS6 family. (126 aa)
eif2gTranslation initiation factor aIF-2 gamma subunit; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily. (410 aa)
rps24eRibosomal protein S24e Rps24e; Belongs to the eukaryotic ribosomal protein eS24 family. (103 aa)
rps27aeRibosomal protein S27ae Rps27ae; Belongs to the eukaryotic ribosomal protein eS31 family. (51 aa)
Abm4_0725Hypothetical protein. (355 aa)
Abm4_0756Glycosyl transferase GT2 family. (230 aa)
cbiTprecorrin-6Y C5,15- methyltransferase (decarboxylating) CbiT; Catalyzes the methylation of C-15 in cobalt-precorrin-6B followed by the decarboxylation of C-12 to form cobalt-precorrin-7. (188 aa)
Abm4_0768Hypothetical protein. (164 aa)
rfcSReplication factor C small subunit RfcS; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcS subfamily. (315 aa)
rfcLReplication factor C large subunit RfcL; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcL subfamily. (552 aa)
hisShistidyl-tRNA synthetase HisS; Belongs to the class-II aminoacyl-tRNA synthetase family. (431 aa)
Abm4_0786Xylose isomerase-like TIM barrel domain-containing protein. (249 aa)
Abm4_0797RNA-binding protein. (159 aa)
rpl37eRibosomal protein L37e Rpl37e; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL37 family. (61 aa)
uvrCExcinuclease ABC C subunit UvrC; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. (589 aa)
ogt6-O-methylguanine DNA methyltransferase Ogt. (206 aa)
Abm4_0839Hydrolase TatD family. (261 aa)
Abm4_0846Archaeal ATPase. (388 aa)
uvrAExcinuclease ABC A subunit UvrA; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (965 aa)
uvrBExcinuclease ABC B subunit UvrB; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissoc [...] (651 aa)
Abm4_0863ATP-dependent DNA helicase UvrD/REP family. (812 aa)
Abm4_0865Phosphoenolpyruvate synthase/pyruvate phosphate dikinase. (881 aa)
rad50DNA double-strand break repair protein Rad50; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex; Belongs to the SMC family. RAD50 subfamily. (925 aa)
mre11DNA double-strand break repair protein Mre11; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity. Belongs to the MRE11/RAD32 family. (380 aa)
Abm4_0882NurA domain-containing protein. (306 aa)
rpl40eRibosomal protein L40e Rpl40e; Belongs to the eukaryotic ribosomal protein eL40 family. (48 aa)
rpl37aeRibosomal protein L37Ae Rpl37ae; Binds to the 23S rRNA. (87 aa)
rrp42Exosome complex RNA-binding protein Rrp42; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site. (263 aa)
rrp41Exosome complex exonuclease Rrp41. (243 aa)
rrp4Exosome complex RNA-binding protein Rrp4; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome. (334 aa)
psmAProteasome alpha subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. (263 aa)
Abm4_0926Ribosomal protein L15e Rpl15e. (184 aa)
gatDglutamyl-tRNA(Gln) amidotransferase subunit D GatD; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate. (435 aa)
gatEglutamyl-tRNA(Gln) amidotransferase subunit E GatE; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate. (625 aa)
Abm4_0966Hypothetical protein. (398 aa)
Abm4_0970RNA methylase. (343 aa)
Abm4_0982Cell wall biosynthesis protein phospho-N-acetylmuramoyl-pentapeptide-transferase family. (357 aa)
cas1-2CRISPR-associated endonuclease Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (334 aa)
polBDNA polymerase small subunit DP1 PolD1; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase; Belongs to the DNA polymerase delta/II small subunit family. (605 aa)
Abm4_1716Transposase. (229 aa)
rfbDdTDP-4-dehydrorhamnose reductase RfbD. (277 aa)
rfbAGlucose-1-phosphate thymidylyltransferase RfbA. (288 aa)
rfbCdTDP-4-dehydrorhamnose 3,5- epimerase RfbC; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (191 aa)
Abm4_1699CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase. (373 aa)
Abm4_1697Glycosyl transferase GT2 family. (322 aa)
Abm4_1696Glycosyl transferase GT2 family. (288 aa)
rpaIReplication factor A RpaI. (789 aa)
radADNA repair and recombination protein RadA; Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules. (311 aa)
ileSisoleucyl-tRNA synthetase IleS; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1107 aa)
ogg8-oxoguanine DNA glycosylase Ogg. (326 aa)
ksgADimethyladenosine transferase KsgA; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily. (287 aa)
rpl21eRibosomal protein L21e Rpl21e; Belongs to the eukaryotic ribosomal protein eL21 family. (96 aa)
csl4Exosome complex RNA-binding protein Csl4; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs. (189 aa)
Abm4_1650NUDIX domain-containing protein. (137 aa)
pcnDNA polymerase sliding clamp subunit PCNA family Pcn; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. (244 aa)
rpl44eRibosomal protein L44e Rpl44e; Binds to the 23S rRNA. (92 aa)
rps27eRibosomal protein S27e Rps27e. (59 aa)
eif2aTranslation initiation factor aIF-2 alpha subunit; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-alpha family. (265 aa)
dnaJMolecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] (381 aa)
gatBAsp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit B GatB; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily. (450 aa)
hjcArchaeal Holliday junction resolvase Hjc; A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination. Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products; Belongs to the Holliday junction resolvase Hjc family. (136 aa)
polB1DNA polymerase family B PolB1. (615 aa)
trm1N2,N2-dimethylguanosine tRNA methyltransferase Trm1; Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. (398 aa)
Abm4_1503Ribosomal protein L10e Rpl10e. (160 aa)
rnhBRibonuclease HII RnhB; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (207 aa)
Abm4_1479Endonuclease IV. (277 aa)
top6ADNA topoisomerase VI subunit A; Relaxes both positive and negative superturns and exhibits a strong decatenase activity; Belongs to the TOP6A family. (371 aa)
top6BDNA topoisomerase VI subunit B; Relaxes both positive and negative superturns and exhibits a strong decatenase activity. (598 aa)
eif1aTranslation initiation factor aIF-1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. (104 aa)
ef1bTranslation elongation factor aEF-1 beta; Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA. (88 aa)
Abm4_1457peptidyl-tRNA hydrolase. (112 aa)
Abm4_1456ATPase RIL. (591 aa)
Abm4_1418Radical SAM domain-containing protein. (304 aa)
mutS2DNA mismatch repair ATPase MutS family; Has ATPase and non-specific DNA-binding activities. Belongs to the DNA mismatch repair MutS family. Archaeal Muts2 subfamily. (641 aa)
xseBExodeoxyribonuclease VII small subunit XseB. (89 aa)
xseAExodeoxyribonuclease VII large subunit XseA. (462 aa)
tyrStyrosyl-tRNA synthetase TyrS; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 3 subfamily. (320 aa)
eif2bTranslation initiation factor aIF-2 beta subunit; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-beta/eIF-5 family. (137 aa)
mcmReplicative DNA helicase Mcm; Belongs to the MCM family. (666 aa)
rrmJRibosomal RNA large subunit methyltransferase J RrmJ; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. (202 aa)
Abm4_1378DEAD/DEAH box helicase domain-containing protein. (867 aa)
nucSHypothetical protein; Cleaves both 3' and 5' ssDNA extremities of branched DNA structures; Belongs to the NucS endonuclease family. (260 aa)
glySglycyl-tRNA synthetase GlyS. (568 aa)
Abm4_1341RNA methyltransferase TrmH family. (303 aa)
Abm4_1287RNA-binding protein. (664 aa)
rpl3pRibosomal protein L3P Rpl3p; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. (336 aa)
rpl4pRibosomal protein L4p Rpl4p; Forms part of the polypeptide exit tunnel. (254 aa)
Your Current Organism:
Methanobrevibacter sp. AbM4
NCBI taxonomy Id: 224719
Other names: M. sp. AbM4
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