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| | cbiG | Cobalamin biosynthesis protein CbiG. (344 aa) |
| | pyrB | Aspartate carbamoyltransferase PyrB. (313 aa) |
| | Abm4_0003 | Flavodoxin domain-containing protein. (161 aa) |
| | hcgA | BioB family protein HcgA. (333 aa) |
| | ribB | 3,4-dihydroxy-2-butanone 4-phosphate synthase RibB; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. (212 aa) |
| | ribK | Riboflavin kinase RibK; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family. (126 aa) |
| | Abm4_0018 | Cobyrinic acid a,c-diamide synthase-related protein. (507 aa) |
| | gatA | Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit A GatA; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). (459 aa) |
| | cbiA | Cobyrinic acid a,c-diamide synthase CbiA; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP- dependent amidation of the two carboxylate groups at positions a and c of Ni-sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source. (468 aa) |
| | fae-hps | Bifunctional formaldehyde-activating enzyme/3- hexulose-6-phosphate synthase Fae/Hps; Catalyzes the condensation of formaldehyde with tetrahydromethanopterin (H(4)MPT) to 5,10- methylenetetrahydromethanopterin; In the N-terminal section; belongs to the formaldehyde- activating enzyme family. (407 aa) |
| | thrS | threonyl-tRNA synthetase ThrS; Belongs to the class-II aminoacyl-tRNA synthetase family. (611 aa) |
| | argS | arginyl-tRNA synthetase ArgS; Belongs to the class-I aminoacyl-tRNA synthetase family. (574 aa) |
| | purD | Phosphoribosylamine-glycine ligase PurD; Belongs to the GARS family. (437 aa) |
| | cobT | Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase CobT; Belongs to the UPF0284 family. (353 aa) |
| | rps15 | Ribosomal protein S15P Rps15p. (132 aa) |
| | leuS | leucyl-tRNA synthetase LeuS; Belongs to the class-I aminoacyl-tRNA synthetase family. (955 aa) |
| | nadE | NAD+ synthetase NadE; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. (270 aa) |
| | cbiE | Precorrin-6y C5,15-methyltransferase (decarboxylating) CbiE. (213 aa) |
| | Abm4_0123 | Hydrogenase expression/formation related protein. (457 aa) |
| | thiC1 | Thiamine biosynthesis protein ThiC1; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. (434 aa) |
| | polD2 | DNA polymerase large subunit DP2 PolD2; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase. (1121 aa) |
| | lysS | lysyl-tRNA synthetase LysS; Belongs to the class-I aminoacyl-tRNA synthetase family. (528 aa) |
| | purB | Adenylosuccinate lyase PurB; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (449 aa) |
| | cyaA | Adenylate cyclase CyaA. (182 aa) |
| | tbp | TATA-box binding protein Tbp; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation. (181 aa) |
| | Abm4_0192 | GTP-binding protein. (369 aa) |
| | Abm4_0193 | Hypothetical protein; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Belongs to the adenylate kinase family. AK6 subfamily. (198 aa) |
| | rps19e | Ribosomal protein S19e Rps19e; May be involved in maturation of the 30S ribosomal subunit. Belongs to the eukaryotic ribosomal protein eS19 family. (146 aa) |
| | rpl39e | Ribosomal protein L39e Rpl39e; Belongs to the eukaryotic ribosomal protein eL39 family. (51 aa) |
| | rpl31e | Ribosomal protein L31e Rpl31e; Belongs to the ribosomal protein L31e family. (88 aa) |
| | eif6 | Translation initiation factor aIF-6; Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex. (224 aa) |
| | rplX | Ribosomal protein LX RplX. (74 aa) |
| | dut | dUTP diphosphatase Dut. (152 aa) |
| | mptE | Hypothetical protein; Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl- 7,8-dihydropterin diphosphate (6-HMDP); Belongs to the archaeal 6-HMPDK family. (242 aa) |
| | mtnP | Methylthioadenosine phosphorylase MtnP; Purine nucleoside phosphorylase involved in purine salvage. (251 aa) |
| | Abm4_0220 | Dinitrogenase iron-molybdenum cofactor biosynthesis protein. (113 aa) |
| | rps3ae | Ribosomal protein S3Ae Rps3ae; Belongs to the eukaryotic ribosomal protein eS1 family. (191 aa) |
| | Abm4_0229 | Anaerobic ribonucleoside-triphosphate reductase activating protein. (236 aa) |
| | dnlI | ATP-dependent DNA ligase DnlI; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. (550 aa) |
| | thiC2 | Thiamine biosynthesis protein ThiC2; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. (424 aa) |
| | tfe | Transcription initiation factor TFIIE alpha subunit Tfe; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabili [...] (151 aa) |
| | spt5 | Ribosomal protein L24 family; Stimulates transcription elongation; Belongs to the archaeal Spt5 family. (160 aa) |
| | rpl11 | Ribosomal protein L11P Rpl11p; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family. (161 aa) |
| | rpl1 | Ribosomal protein L1P Rpl1p; Binds directly to 23S rRNA. Probably involved in E site tRNA release. (212 aa) |
| | rpl10 | Acidic ribosomal protein P0 RplPO; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (336 aa) |
| | rpl12 | Ribosomal protein L12P Rpl12p; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the eukaryotic ribosomal protein P1/P2 family. (100 aa) |
| | alaS | alanyl-tRNA synthetase AlaS; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (906 aa) |
| | thiI | Thiamine biosynthesis ATP pyrophosphatase ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (382 aa) |
| | queC | ExsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. (226 aa) |
| | cobS | Cobalamin-5-phosphate synthase CobS; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. (288 aa) |
| | korC | 2-oxoglutarate ferredoxin oxidoreductase subunit gamma KorC. (183 aa) |
| | thiE | Thiamine monophosphate synthase ThiE; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (208 aa) |
| | thiM | Hydroxyethylthiazole kinase ThiM; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. (291 aa) |
| | rpoH | DNA-directed RNA polymerase subunit H RpoH; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family. (81 aa) |
| | rpoB | DNA-directed RNA polymerase subunit B RpoB; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1117 aa) |
| | rpoA1 | DNA-directed RNA polymerase subunit A' RpoA1; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (869 aa) |
| | rpoA2 | DNA-directed RNA polymerase subunit A'' RpoA2; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (423 aa) |
| | rpl30e | Ribosomal protein L30e Rpl30e; Belongs to the eukaryotic ribosomal protein eL30 family. (99 aa) |
| | nusA | Transcription elongation factor NusA-like protein; Participates in transcription termination. Belongs to the NusA family. (143 aa) |
| | rps12 | Ribosomal protein S12P Rps12p; With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family. (141 aa) |
| | rps7 | Ribosomal protein S7P Rps7p; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center; Belongs to the universal ribosomal protein uS7 family. (187 aa) |
| | fusA | Translation elongation factor aEF-2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF [...] (730 aa) |
| | tuf | Translation elongation factor aEF-1 alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. (413 aa) |
| | rps10 | Ribosomal protein S10P Rps10p; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (102 aa) |
| | cbiJ | Precorrin-6x reductase CbiJ. (273 aa) |
| | carA | Carbamoyl-phosphate synthase small subunit CarA; Belongs to the CarA family. (369 aa) |
| | carB | Carbamoylphosphate synthase large subunit CarB; Belongs to the CarB family. (1065 aa) |
| | Abm4_0404 | tRNA binding domain-containing protein. (241 aa) |
| | nadX1 | L-aspartate dehydrogenase NadX1; Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate. (254 aa) |
| | ahaE | A1A0 archaeal ATP synthase subunit E AhaE; Produces ATP from ADP in the presence of a proton gradient across the membrane. (207 aa) |
| | ahaC | A1A0 archaeal ATP synthase subunit C AhaC; Produces ATP from ADP in the presence of a proton gradient across the membrane. (384 aa) |
| | ahaF | A1A0 archaeal ATP synthase subunit F AhaF; Produces ATP from ADP in the presence of a proton gradient across the membrane. (104 aa) |
| | ahaA | A1A0 archaeal ATP synthase subunit A AhaA; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family. (584 aa) |
| | ahaB | A1A0 archaeal ATP synthase subunit B AhaB; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit. (461 aa) |
| | ahaD | A1A0 archaeal ATP synthase subunit D AhaD; Produces ATP from ADP in the presence of a proton gradient across the membrane. (226 aa) |
| | Abm4_0434 | 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein. (267 aa) |
| | Abm4_0435 | Hypothetical protein. (134 aa) |
| | dnaG | DNA primase DnaG; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. (427 aa) |
| | tfb | Transcription initiation factor TFIIB Tfb; Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB). (310 aa) |
| | pyrH | Uridylate kinase PyrH; Catalyzes the reversible phosphorylation of UMP to UDP. (225 aa) |
| | prf1 | Peptide chain release factor aRF1; Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. (411 aa) |
| | Abm4_0458 | Orotate phosphoribosyltransferase-like protein; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (204 aa) |
| | hemC | Porphobilinogen deaminase HemC; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (291 aa) |
| | nadK | Inositol-1 monophosphatase/fructose-1,6-bisphosphatase/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (613 aa) |
| | eif5a | Translation initiation factor eIF-5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family. (135 aa) |
| | Abm4_0466 | Pyridoxal/pyridoxine/pyridoxamine kinase. (282 aa) |
| | pyrI | Aspartate carbamoyltransferase regulatory subunit PyrI; Involved in allosteric regulation of aspartate carbamoyltransferase. (157 aa) |
| | ribL | FAD synthetase RibL; Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme. (152 aa) |
| | Abm4_0515 | Hypothetical protein. (211 aa) |
| | Abm4_0526 | Archaeal histone. (66 aa) |
| | cbiD | Cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. (382 aa) |
| | rps17e | Ribosomal protein S17e Rps17e; Belongs to the eukaryotic ribosomal protein eS17 family. (64 aa) |
| | Abm4_0588 | Pyridoxamine 5'-phosphate oxidase family protein. (134 aa) |
| | cbiP | Cobyric acid synthase CbiP; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (525 aa) |
| | prs | Ribose-phosphate diphosphokinase Prs; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P). (296 aa) |
| | Abm4_0612 | Hypothetical protein. (136 aa) |
| | thyA | Thymidylate synthase ThyA. (239 aa) |
| | cbiF | Precorrin-4 C11-methyltransferase CbiF. (251 aa) |
| | cbiX1 | Cobalamin biosynthesis protein CbiX1; Catalyzes the insertion of Co(2+) into sirohydrochlorin as part of the anaerobic pathway to cobalamin biosynthesis. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the insertion of Ni(2+) into sirohydrochlorin to yield Ni- sirohydrochlorin. (152 aa) |
| | cbiX2 | Cobalamin biosynthesis protein CbiX2. (307 aa) |
| | metG | methionyl-tRNA synthetase MetG; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (671 aa) |
| | priB | DNA primase large subunit PriB; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair. (452 aa) |
| | priA | DNA primase small subunit PriA; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthe [...] (334 aa) |
| | coaA | Pantothenate kinase CoaA. (296 aa) |
| | ribD | Diaminohydroxyphosphoribosylaminopyrimidine reductase RibD. (219 aa) |
| | aspS | aspartyl-tRNA synthetase AspS; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn). (439 aa) |
| | cbiC | precorrin-8X methylmutase CbiC. (213 aa) |
| | hemL | Glutamate-1-semialdehyde-2,1-aminomutase HemL. (428 aa) |
| | trpS | tryptophanyl-tRNA synthetase TrpS; Catalyzes the attachment of tryptophan to tRNA(Trp). (363 aa) |
| | Abm4_0708 | Archaeal histone. (67 aa) |
| | rpl7ae | Ribosomal protein L7Ae Rpl7ae; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs. (123 aa) |
| | rps28e | Ribosomal protein S28e Rps28e; Belongs to the eukaryotic ribosomal protein eS28 family. (68 aa) |
| | rpl24e | Ribosomal protein L24e Rpl24e; Binds to the 23S rRNA. (53 aa) |
| | ndk | Nucleoside diphosphate kinase Ndk; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. (150 aa) |
| | infB | Translation initiation factor IF-2; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2. (595 aa) |
| | rps6e | Ribosomal protein S6e Rps6e; Belongs to the eukaryotic ribosomal protein eS6 family. (126 aa) |
| | eif2g | Translation initiation factor aIF-2 gamma subunit; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily. (410 aa) |
| | rpoE1 | DNA-directed RNA polymerase subunit E' RpoE1. (185 aa) |
| | Abm4_0719 | Hypothetical protein; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). (166 aa) |
| | rps24e | Ribosomal protein S24e Rps24e; Belongs to the eukaryotic ribosomal protein eS24 family. (103 aa) |
| | rps27ae | Ribosomal protein S27ae Rps27ae; Belongs to the eukaryotic ribosomal protein eS31 family. (51 aa) |
| | purF | Amidophosphoribosyltransferase PurF; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (469 aa) |
| | pyrF | Orotidine 5'-phosphate decarboxylase PyrF; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (213 aa) |
| | cbiM2 | Cobalamin biosynthesis protein CbiM2; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. (226 aa) |
| | cbiN2 | Cobalt transport protein CbiN2; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import; Belongs to the CbiN family. (97 aa) |
| | ribC | Riboflavin synthase RibC. (152 aa) |
| | guaB | Inosine-5'-monophosphate dehydrogenase GuaB; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (494 aa) |
| | cbiT | precorrin-6Y C5,15- methyltransferase (decarboxylating) CbiT; Catalyzes the methylation of C-15 in cobalt-precorrin-6B followed by the decarboxylation of C-12 to form cobalt-precorrin-7. (188 aa) |
| | Abm4_0771 | Nicotinamide-nucleotide adenylyltransferase. (178 aa) |
| | hisS | histidyl-tRNA synthetase HisS; Belongs to the class-II aminoacyl-tRNA synthetase family. (431 aa) |
| | arfB | Creatinine amidohydrolase ArfB; Catalyzes the hydrolysis of the formamide of 2-amino-5- formylamino-6-ribosylamino-4(3H)-pyrimidinone 5'-monophosphate (FAPy) to form 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (APy). (230 aa) |
| | Abm4_0797 | RNA-binding protein. (159 aa) |
| | rpl37e | Ribosomal protein L37e Rpl37e; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL37 family. (61 aa) |
| | panC | Pantothenate synthase PanC. (245 aa) |
| | pyrG | CTP synthase PyrG; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (546 aa) |
| | panE | 2-dehydropantoate 2-reductase PanE; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (315 aa) |
| | Abm4_0848 | Archaeal histone. (67 aa) |
| | Abm4_0873 | Cell wall biosynthesis protein Mur ligase family. (428 aa) |
| | rpl40e | Ribosomal protein L40e Rpl40e; Belongs to the eukaryotic ribosomal protein eL40 family. (48 aa) |
| | pdxS | Pyridoxal biosynthesis lyase PdxS; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. (293 aa) |
| | Abm4_0916 | DNA-directed RNA polymerase subunit P RpoP. (43 aa) |
| | rpl37ae | Ribosomal protein L37Ae Rpl37ae; Binds to the 23S rRNA. (87 aa) |
| | Abm4_0926 | Ribosomal protein L15e Rpl15e. (184 aa) |
| | ehaO | Energy-converting hydrogenase A subunit O EhaO; Belongs to the complex I 49 kDa subunit family. (372 aa) |
| | acsA | acetyl-CoA synthetase AcsA. (564 aa) |
| | gatD | glutamyl-tRNA(Gln) amidotransferase subunit D GatD; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate. (435 aa) |
| | gatE | glutamyl-tRNA(Gln) amidotransferase subunit E GatE; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate. (625 aa) |
| | guaA | GMP synthase subunit A GuaA; Catalyzes the synthesis of GMP from XMP. (187 aa) |
| | guaAb | GMP synthase subunit B GuaAb; Catalyzes the synthesis of GMP from XMP. (308 aa) |
| | Abm4_0981 | Cell wall biosynthesis protein Mur ligase family. (493 aa) |
| | Abm4_0983 | D-alanine-D-alanine ligase. (376 aa) |
| | Abm4_0989 | SAM-dependent methyltransferase. (274 aa) |
| | pdxT | Pyridoxine biosynthesis glutamine amidotransferase subunit PdxT; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. (196 aa) |
| | tfs1 | Transcription factor S Tfs1; Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (106 aa) |
| | Abm4_1032 | NUDIX domain-containing protein. (127 aa) |
| | serS | seryl-tRNA synthetase SerS. (425 aa) |
| | purC | Phosphoribosylaminoimidazole-succinocarboxamide synthase PurC; Belongs to the SAICAR synthetase family. (246 aa) |
| | purS | Phosphoribosylformylglycinamidine (FGAM) synthase PurS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought t [...] (90 aa) |
| | purQ | Phosphoribosylformylglycinamidine (FGAM) synthase PurQ; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought t [...] (217 aa) |
| | cobA | uroporphyrin-III C-methyltransferase CobA; Belongs to the precorrin methyltransferase family. (248 aa) |
| | hemD | uroporphyrinogen-III synthase HemD; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (261 aa) |
| | rps8e | Ribosomal protein S8e Rps8e. (125 aa) |
| | polB2 | DNA polymerase family B PolB2. (236 aa) |
| | Abm4_1149 | Hydrolase HAD superfamily. (231 aa) |
| | pheS | phenylalanyl-tRNA synthetase alpha subunit PheS; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily. (520 aa) |
| | Abm4_1166 | Hypothetical protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily. (216 aa) |
| | hemB | Delta-aminolevulinic acid dehydratase HemB; Belongs to the ALAD family. (337 aa) |
| | Abm4_1182 | Metallo-beta-lactamase superfamily protein. (283 aa) |
| | Abm4_1189 | Radical SAM domain-containing protein. (504 aa) |
| | cysS | cysteinyl-tRNA synthetase CysS; Belongs to the class-I aminoacyl-tRNA synthetase family. (487 aa) |
| | valS | valyl-tRNA synthetase ValS; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily. (909 aa) |
| | pheT | phenylalanyl-tRNA synthetase subunit beta PheT. (552 aa) |
| | Abm4_1201 | 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein. (241 aa) |
| | proS | prolyl-tRNA synthetase ProS; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). (469 aa) |
| | thiD | Phosphomethylpyrimidine kinase ThiD. (247 aa) |
| | purA | Adenylosuccinate synthetase PurA; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (340 aa) |
| | gltX | glutamyl-tRNA synthetase GltX; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (557 aa) |
| | rps2p | Ribosomal protein S2P Rps2p; Belongs to the universal ribosomal protein uS2 family. (200 aa) |
| | rpoK | DNA-directed RNA polymerase subunit K RpoK; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit family. (60 aa) |
| | rpoN | DNA-directed RNA polymerase subunit N RpoN. (56 aa) |
| | rps9p | Ribosomal protein S9P Rps9p; Belongs to the universal ribosomal protein uS9 family. (132 aa) |
| | rpl13 | Ribosomal protein L13P Rpl13p; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (140 aa) |
| | rpl18e | Ribosomal protein L18e Rpl18e; Belongs to the eukaryotic ribosomal protein eL18 family. (121 aa) |
| | rpoD | DNA-directed RNA polymerase subunit D RpoD; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (267 aa) |
| | rps11 | Ribosomal protein S11P Rps11p; Located on the platform of the 30S subunit. Belongs to the universal ribosomal protein uS11 family. (130 aa) |
| | rps4p | Ribosomal protein S4P Rps4p; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (180 aa) |
| | rps13 | Ribosomal protein S13P Rps13p; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement; Belongs to the universal ribosomal protein uS13 family. (153 aa) |
| | Abm4_1248 | Ribosomal protein L14e Rpl14e. (73 aa) |
| | cmk | Cytidylate kinase Cmk. (172 aa) |
| | rpl34e | Ribosomal protein L34e Rpl34e; Belongs to the eukaryotic ribosomal protein eL34 family. (88 aa) |
| | adk | Adenylate kinase Adk; Belongs to the archaeal adenylate kinase family. (185 aa) |
| | rpl15 | Ribosomal protein L15P Rpl15p; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (145 aa) |
| | rpl30 | Ribosomal protein L30P Rpl30p. (152 aa) |
| | rps5p | Ribosomal protein S5P Rps5p; With S4 and S12 plays an important role in translational accuracy. (214 aa) |
| | rpl18 | Ribosomal protein L18P Rpl18p; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (193 aa) |
| | rpl19e | Ribosomal protein L19e Rpl19e; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family. (149 aa) |
| | Abm4_1259 | Ribosomal protein L32e Rpl32e. (108 aa) |
| | rpl6p | Ribosomal protein L6P Rpl6p; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (178 aa) |
| | rps8p | Ribosomal protein S8P Rps8p; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (130 aa) |
| | rps14 | Ribosomal protein S14P Rps14p; Binds 16S rRNA, required for the assembly of 30S particles. (47 aa) |
| | rpl5p | Ribosomal protein L5P Rpl5p; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (171 aa) |
| | rps4e | Ribosomal protein S4e Rps4e; Belongs to the eukaryotic ribosomal protein eS4 family. (241 aa) |
| | rpl24 | Ribosomal protein L24P Rpl24p; Located at the polypeptide exit tunnel on the outside of the subunit. (116 aa) |
| | rpl14 | Ribosomal protein L14P Rpl14p; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (132 aa) |
| | rps17 | Ribosomal protein S17P Rps17p; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (105 aa) |
| | Abm4_1269 | Translation initiation factor aSUI1; Belongs to the SUI1 family. (115 aa) |
| | rpl29 | Ribosomal protein L29P Rpl29p; Belongs to the universal ribosomal protein uL29 family. (68 aa) |
| | rps3p | Ribosomal protein S3P Rps3p; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family. (254 aa) |
| | rpl22 | Ribosomal protein L22P Rpl22p; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome. (154 aa) |
| | rps19p | Ribosomal protein S19P Rps19p; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (136 aa) |
| | rpl2p | Ribosomal protein L2P Rpl2p; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (241 aa) |
| | rpl23 | Ribosomal protein L23P Rpl23p; Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Belongs to the universal ribosomal protein uL23 family. (86 aa) |
| | rpl4p | Ribosomal protein L4p Rpl4p; Forms part of the polypeptide exit tunnel. (254 aa) |
| | rpl3p | Ribosomal protein L3P Rpl3p; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. (336 aa) |
| | Abm4_1287 | RNA-binding protein. (664 aa) |
| | coaD | Phosphopantetheine adenylyltransferase CoaD. (151 aa) |
| | Abm4_1324 | Methanogenesis marker protein 2. (328 aa) |
| | pyrE | Orotate phosphoribosyltransferase PyrE; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (175 aa) |
| | iorB | Indolepyruvate ferredoxin oxidoreductase beta subunit IorB. (198 aa) |
| | dcd | Deoxycytidine triphosphate deaminase Dcd; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate. (194 aa) |
| | glyS | glycyl-tRNA synthetase GlyS. (568 aa) |
| | upp | Uracil phosphoribosyltransferase Upp. (209 aa) |
| | Abm4_1357 | Pyridoxamine 5'-phosphate oxidase family protein. (130 aa) |
| | nadC | Nicotinate-nucleotide pyrophosphorylase NadC; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. (280 aa) |
| | nadA | Quinolinate synthetase A protein NadA; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (304 aa) |
| | purP | 5-formaminoimidazole-4-carboxamide-1-(beta)-D- ribofuranosyl 5'-monophosphate-formate ligase PurP; Catalyzes the ATP- and formate-dependent formylation of 5- aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates. (363 aa) |
| | eif2b | Translation initiation factor aIF-2 beta subunit; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-beta/eIF-5 family. (137 aa) |
| | tyrS | tyrosyl-tRNA synthetase TyrS; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 3 subfamily. (320 aa) |
| | tmk | Thymidylate kinase Tmk. (197 aa) |
| | trpD | Anthranilate phosphoribosyltransferase TrpD; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (355 aa) |
| | trpA | Tryptophan synthase alpha subunit TrpA; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (270 aa) |
| | trpB | Tryptophan synthase subunit beta TrpB; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (394 aa) |
| | trpF | N-(5'-phosphoribosyl)anthranilate isomerase TrpF; Belongs to the TrpF family. (222 aa) |
| | trpC | Indole-3-glycerol-phosphate synthase TrpC. (265 aa) |
| | trpG | Anthranilate synthase component II TrpG. (188 aa) |
| | trpE | Anthranilate synthase component I TrpE. (415 aa) |
| | porC | Pyruvate ferredoxin oxidoreductase gamma subunit PorC. (173 aa) |
| | porD | Pyruvate ferredoxin oxidoreductase delta subunit PorD. (82 aa) |
| | porA | Pyruvate ferredoxin oxidoreductase alpha subunit PorA. (384 aa) |
| | cbiB | Cobalamin biosynthesis protein CbiB; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (369 aa) |
| | porB | Pyruvate ferredoxin oxidoreductase beta subunit PorB. (288 aa) |
| | Abm4_1455 | 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein. (244 aa) |
| | Abm4_1456 | ATPase RIL. (591 aa) |
| | Abm4_1457 | peptidyl-tRNA hydrolase. (112 aa) |
| | ef1b | Translation elongation factor aEF-1 beta; Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA. (88 aa) |
| | thi4 | Thiazole biosynthesis enzyme; Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur. (262 aa) |
| | eif1a | Translation initiation factor aIF-1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. (104 aa) |
| | hemA | glutamyl-tRNA reductase HemA; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (412 aa) |
| | cysG | Siroheme synthase CysG. (223 aa) |
| | purO | IMP cyclohydrolase PurO; Catalyzes the cyclization of 5-formylamidoimidazole-4- carboxamide ribonucleotide to IMP. (210 aa) |
| | mptD | Hypothetical protein; Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD); Belongs to the archaeal dihydroneopterin aldolase family. (124 aa) |
| | mfnA | L-tyrosine decarboxylase MfnA; Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis. Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis; Belongs to the group II decarboxylase family. MfnA subfamily. (387 aa) |
| | Abm4_1503 | Ribosomal protein L10e Rpl10e. (160 aa) |
| | pyrC | Dihydroorotase PyrC; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. (419 aa) |
| | cobY | GTP:adenosylcobinamide-phosphate guanylyltransferase CobY. (206 aa) |
| | mptA | GTP cyclohydrolase MptA; Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin. (311 aa) |
| | cofG | FO synthase subunit 1 CofG; Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) from 5-amino-5-(4-hydroxybenzyl)-6-(D- ribitylimino)-5,6-dihydrouracil. (379 aa) |
| | purM | Phosphoribosylformylglycinamidine cyclo-ligase PurM. (340 aa) |
| | polB1 | DNA polymerase family B PolB1. (615 aa) |
| | pyrK | Dihydroorotate dehydrogenase electron transfer subunit PyrK. (265 aa) |
| | pyrD | Dihydroorotate dehydrogenase PyrD; Catalyzes the conversion of dihydroorotate to orotate. (303 aa) |
| | coaB | Phosphopantothenate-cysteine ligase CoaB. (219 aa) |
| | coaC | Phosphopantothenoylcysteine decarboxylase CoaC. (171 aa) |
| | queE | Radical SAM domain-containing protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (233 aa) |
| | Abm4_1570 | 6-pyruvoyl tetrahydropterin synthase/QueD family protein. (171 aa) |
| | ehbN | Energy-converting hydrogenase B subunit N EhbN. (378 aa) |
| | Abm4_1608 | Radical SAM domain-containing protein. (333 aa) |
| | gatB | Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit B GatB; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily. (450 aa) |
| | Abm4_1613 | Phosphoribosylaminoimidazole carboxylase-related protein. (262 aa) |
| | nadX2 | L-aspartate dehydrogenase NadX2. (254 aa) |
| | eif2a | Translation initiation factor aIF-2 alpha subunit; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-alpha family. (265 aa) |
| | rps27e | Ribosomal protein S27e Rps27e. (59 aa) |
| | rpl44e | Ribosomal protein L44e Rpl44e; Binds to the 23S rRNA. (92 aa) |
| | tfs2 | Transcription factor S Tfs2; Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (105 aa) |
| | rpoL | DNA-directed RNA polymerase subunit L RpoL; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoL/eukaryotic RPB11/RPC19 RNA polymerase subunit family. (94 aa) |
| | apt | Adenine phosphoribosyltransferase Apt; Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily. (191 aa) |
| | rpl21e | Ribosomal protein L21e Rpl21e; Belongs to the eukaryotic ribosomal protein eL21 family. (96 aa) |
| | rpoF | DNA-directed RNA polymerase subunit F RpoF. (110 aa) |
| | Abm4_1668 | NUDIX domain-containing protein. (133 aa) |
| | cbiL | Precorrin-2 C20-methyltransferase CbiL; Belongs to the precorrin methyltransferase family. (231 aa) |
| | purL | Phosphoribosylformylglycinamidine (FGAM) synthase II PurL; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is though [...] (718 aa) |
| | ileS | isoleucyl-tRNA synthetase IleS; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1107 aa) |
| | afpA | Archaeoflavoprotein AfpA. (235 aa) |
| | rfbC | dTDP-4-dehydrorhamnose 3,5- epimerase RfbC; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (191 aa) |
| | Abm4_1713 | Nucleotide sugar dehydrogenase. (442 aa) |
| | ribH | 6,7-dimethyl-8- ribityllumazine synthase RibH; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (141 aa) |
| | purE | Phosphoribosylaminoimidazole carboxylase purE; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (343 aa) |
| | thiL | Thiamine monphosphate kinase ThiL; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (344 aa) |
| | cbiH | precorrin-3B C17-methyltransferase CbiH. (356 aa) |
| | polB | DNA polymerase small subunit DP1 PolD1; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase; Belongs to the DNA polymerase delta/II small subunit family. (605 aa) |
