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| | fumA2 | Fumarate hydratase FumA2. (293 aa) |
| | Abm4_0433 | ATP-grasp domain-containing protein. (424 aa) |
| | dnaG | DNA primase DnaG; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. (427 aa) |
| | tfb | Transcription initiation factor TFIIB Tfb; Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB). (310 aa) |
| | Abm4_0446 | TauE family transporter. (240 aa) |
| | nadK | Inositol-1 monophosphatase/fructose-1,6-bisphosphatase/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (613 aa) |
| | speB | Agmatinase SpeB; Belongs to the arginase family. (301 aa) |
| | cab | Carbonic anhydrase Cab. (176 aa) |
| | pyrI | Aspartate carbamoyltransferase regulatory subunit PyrI; Involved in allosteric regulation of aspartate carbamoyltransferase. (157 aa) |
| | Abm4_0504 | Hypothetical protein. (385 aa) |
| | Abm4_0510 | Molybdenum cofactor biosynthesis-related protein. (509 aa) |
| | Abm4_0525 | MiaB-like tRNA modifying enzyme. (429 aa) |
| | Abm4_0530 | Histone acetyltransferase ELP3 family. (570 aa) |
| | Abm4_0577 | Peptidase M48 family. (369 aa) |
| | Abm4_0579 | Hypothetical protein. (389 aa) |
| | Abm4_0585 | Hypothetical protein. (221 aa) |
| | prs | Ribose-phosphate diphosphokinase Prs; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P). (296 aa) |
| | hypA | Hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. (124 aa) |
| | hypB | Hydrogenase accessory protein HypB. (220 aa) |
| | metE | Methionine synthase MetE. (321 aa) |
| | cbiX1 | Cobalamin biosynthesis protein CbiX1; Catalyzes the insertion of Co(2+) into sirohydrochlorin as part of the anaerobic pathway to cobalamin biosynthesis. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the insertion of Ni(2+) into sirohydrochlorin to yield Ni- sirohydrochlorin. (152 aa) |
| | cbiX2 | Cobalamin biosynthesis protein CbiX2. (307 aa) |
| | Abm4_0630 | Rubredoxin. (54 aa) |
| | Abm4_0633 | TauE family transporter. (259 aa) |
| | metG | methionyl-tRNA synthetase MetG; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (671 aa) |
| | priB | DNA primase large subunit PriB; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair. (452 aa) |
| | priA | DNA primase small subunit PriA; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthe [...] (334 aa) |
| | cca | tRNA nucleotidyltransferase Cca; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. (461 aa) |
| | feoA | Ferrous iron transport protein A FeoA. (79 aa) |
| | uppS | Undecaprenyl pyrophosphate synthetase UppS; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids. (254 aa) |
| | hisD | Histidinol dehydrogenase HisD; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (427 aa) |
| | aspS | aspartyl-tRNA synthetase AspS; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn). (439 aa) |
| | Abm4_0687 | Hypothetical protein. (98 aa) |
| | hdrA1 | CoB--CoM heterodisulfide reductase subunit A HdrA1; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). (776 aa) |
| | fprA1 | F420H2 oxidase FprA1. (409 aa) |
| | Abm4_0703 | Iron-dependent repressor. (241 aa) |
| | rpl24e | Ribosomal protein L24e Rpl24e; Binds to the 23S rRNA. (53 aa) |
| | ndk | Nucleoside diphosphate kinase Ndk; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. (150 aa) |
| | eif2g | Translation initiation factor aIF-2 gamma subunit; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily. (410 aa) |
| | Abm4_0716 | Hypothetical protein. (128 aa) |
| | rpoE2 | DNA-directed RNA polymerase subunit E'' RpoE2; Stimulates transcription elongation; Belongs to the archaeal Spt4 family. (62 aa) |
| | rps27ae | Ribosomal protein S27ae Rps27ae; Belongs to the eukaryotic ribosomal protein eS31 family. (51 aa) |
| | purF | Amidophosphoribosyltransferase PurF; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (469 aa) |
| | Abm4_0733 | 4Fe-4S iron sulfur cluster binding protein NifH/frxC family; Belongs to the NifH/BchL/ChlL family. (267 aa) |
| | Abm4_0742 | Radical SAM domain-containing protein. (376 aa) |
| | guaB | Inosine-5'-monophosphate dehydrogenase GuaB; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (494 aa) |
| | mobA | Molybdopterin-guanine dinucleotide biosynthesis protein A MobA; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor. (208 aa) |
| | cofH | FO synthase subunit 2 CofH; Catalyzes the radical-mediated synthesis of 5-amino-5-(4- hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil from 5-amino-6-(D- ribitylamino)uracil and L-tyrosine. (374 aa) |
| | Abm4_0776 | Rubredoxin; Rubredoxin is a small nonheme, iron protein lacking acid- labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule. (53 aa) |
| | Abm4_0777 | Rubredoxin. (44 aa) |
| | Abm4_0778 | Ferritin-like domain-containing protein. (169 aa) |
| | hisI | phosphoribosyl-AMP cyclohydrolase HisI; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. (139 aa) |
| | htpX | Peptidase M48 family; Belongs to the peptidase M48B family. (321 aa) |
| | arfB | Creatinine amidohydrolase ArfB; Catalyzes the hydrolysis of the formamide of 2-amino-5- formylamino-6-ribosylamino-4(3H)-pyrimidinone 5'-monophosphate (FAPy) to form 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (APy). (230 aa) |
| | rpl37e | Ribosomal protein L37e Rpl37e; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL37 family. (61 aa) |
| | Abm4_0803 | Hypothetical protein. (152 aa) |
| | Abm4_0809 | Homoserine kinase. (410 aa) |
| | pyrG | CTP synthase PyrG; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (546 aa) |
| | pepA | Glutamyl aminopeptidase PepA. (356 aa) |
| | parA | Chromosome partitioning ATPase ParA; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (288 aa) |
| | fdhA2 | Formate dehydrogenase alpha subunit FdhA2. (343 aa) |
| | uvrA | Excinuclease ABC A subunit UvrA; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (965 aa) |
| | Abm4_0866 | Hypothetical protein. (401 aa) |
| | rad50 | DNA double-strand break repair protein Rad50; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex; Belongs to the SMC family. RAD50 subfamily. (925 aa) |
| | mre11 | DNA double-strand break repair protein Mre11; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity. Belongs to the MRE11/RAD32 family. (380 aa) |
| | Abm4_0882 | NurA domain-containing protein. (306 aa) |
| | Abm4_0883 | Geranylgeranylglyceryl phosphate synthase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. (249 aa) |
| | Abm4_0908 | Iron-dependent repressor. (213 aa) |
| | Abm4_0916 | DNA-directed RNA polymerase subunit P RpoP. (43 aa) |
| | rpl37ae | Ribosomal protein L37Ae Rpl37ae; Binds to the 23S rRNA. (87 aa) |
| | ehaR | Energy-converting hydrogenase A subunit R EhaR. (361 aa) |
| | ehaO | Energy-converting hydrogenase A subunit O EhaO; Belongs to the complex I 49 kDa subunit family. (372 aa) |
| | Abm4_0965 | Hypothetical protein. (240 aa) |
| | Abm4_0966 | Hypothetical protein. (398 aa) |
| | Abm4_0978 | Hypothetical protein. (134 aa) |
| | Abm4_0983 | D-alanine-D-alanine ligase. (376 aa) |
| | nikR | Nickel responsive transcriptional regulator NikR; Transcriptional regulator; Belongs to the transcriptional regulatory CopG/NikR family. (147 aa) |
| | gltA | Glutamate synthase alpha subunit GltA; Belongs to the glutamate synthase family. (497 aa) |
| | aksF | Isohomocitrate dehydrogenase AksF. (337 aa) |
| | Abm4_1002 | Alcohol dehydrogenase. (339 aa) |
| | Abm4_1006 | Hypothetical protein. (105 aa) |
| | tgtA | Archaeosine tRNA-ribosyltransferase TgtA; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family. (659 aa) |
| | tfs1 | Transcription factor S Tfs1; Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (106 aa) |
| | Abm4_1039 | Metallo-beta-lactamase superfamily protein. (291 aa) |
| | Abm4_1065 | Radical SAM domain-containing protein. (298 aa) |
| | cas2-2 | CRISPR-associated endoribonuclease Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (91 aa) |
| | cas1-2 | CRISPR-associated endonuclease Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (334 aa) |
| | Abm4_1099 | Hypothetical protein. (229 aa) |
| | Abm4_1129 | Radical SAM domain-containing protein. (492 aa) |
| | Abm4_1131 | LemA family protein. (184 aa) |
| | Abm4_1140 | CRISPR-associated protein Cas4; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Belongs to the CRISPR-associated exonuclease Cas4 family. (233 aa) |
| | hypE | Hydrogenase expression/formation protein HypE. (336 aa) |
| | xth | Exodeoxyribonuclease III Xth. (257 aa) |
| | pheS | phenylalanyl-tRNA synthetase alpha subunit PheS; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily. (520 aa) |
| | ppaC | Manganese-dependent inorganic pyrophosphatase PpaC. (306 aa) |
| | hemB | Delta-aminolevulinic acid dehydratase HemB; Belongs to the ALAD family. (337 aa) |
| | dfx | Desulfoferrodoxin Dfx. (127 aa) |
| | Abm4_1183 | NifU-like FeS cluster assembly scaffold protein. (127 aa) |
| | nifS | Cysteine desulfurase NifS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. (401 aa) |
| | acs | ADP-dependent acetyl-CoA synthetase Acs. (698 aa) |
| | Abm4_1189 | Radical SAM domain-containing protein. (504 aa) |
| | cysS | cysteinyl-tRNA synthetase CysS; Belongs to the class-I aminoacyl-tRNA synthetase family. (487 aa) |
| | pheT | phenylalanyl-tRNA synthetase subunit beta PheT. (552 aa) |
| | Abm4_1202 | Hypothetical protein. (136 aa) |
| | egsA | NAD(P)-dependent glycerol-1-phosphate dehydrogenase EgsA; Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1- phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea. (347 aa) |
| | purA | Adenylosuccinate synthetase PurA; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (340 aa) |
| | idsA | Bifunctional short chain isoprenyl diphosphate synthase IdsA; Belongs to the FPP/GGPP synthase family. (331 aa) |
| | rnj | RNA-metabolising metallo-beta-lactamase; An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation; Belongs to the metallo-beta-lactamase superfamily. RNA- metabolizing metallo-beta-lactamase-like family. Archaeal RNase J subfamily. (451 aa) |
| | fni | Isopentenyl diphosphate delta-isomerase Fni; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). (353 aa) |
| | mvk | Mevalonate kinase Mvk; Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)- mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids; Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (413 aa) |
| | eno | Phosphopyruvate hydratase Eno; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (415 aa) |
| | rpoD | DNA-directed RNA polymerase subunit D RpoD; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (267 aa) |
| | rps14 | Ribosomal protein S14P Rps14p; Binds 16S rRNA, required for the assembly of 30S particles. (47 aa) |
| | pycA | Pyruvate carboxylase subunit A PycA. (495 aa) |
| | Abm4_1294 | Radical SAM domain-containing protein. (523 aa) |
| | Abm4_1297 | Iron-containing alcohol dehydrogenase. (398 aa) |
| | Abm4_1301 | CBS domain-containing protein. (134 aa) |
| | hdrC2 | CoB--CoM heterodisulfide reductase subunit C HdrC2. (347 aa) |
| | Abm4_1311 | Radical SAM domain-containing protein. (480 aa) |
| | Abm4_1314 | Rubrerythrin. (181 aa) |
| | nifB | Nitrogenase cofactor biosynthesis protein NifB. (307 aa) |
| | Abm4_1326 | Hypothetical protein. (167 aa) |
| | pyrE | Orotate phosphoribosyltransferase PyrE; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (175 aa) |
| | iorA | Indolepyruvate ferredoxin oxidoreductase alpha subunit IorA; Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates. (634 aa) |
| | upp | Uracil phosphoribosyltransferase Upp. (209 aa) |
| | Abm4_1363 | ZPR1 zinc-finger domain-containing protein. (194 aa) |
| | rnz | Ribonuclease Z Rnz; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family. (297 aa) |
| | nadA | Quinolinate synthetase A protein NadA; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (304 aa) |
| | Abm4_1373 | Hypothetical protein. (131 aa) |
| | Abm4_1381 | Hypothetical protein. (220 aa) |
| | purP | 5-formaminoimidazole-4-carboxamide-1-(beta)-D- ribofuranosyl 5'-monophosphate-formate ligase PurP; Catalyzes the ATP- and formate-dependent formylation of 5- aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates. (363 aa) |
| | trpD | Anthranilate phosphoribosyltransferase TrpD; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (355 aa) |
| | trpE | Anthranilate synthase component I TrpE. (415 aa) |
| | Abm4_1418 | Radical SAM domain-containing protein. (304 aa) |
| | Abm4_1419 | Radical SAM domain-containing protein. (364 aa) |
| | Abm4_1422 | Hypothetical protein. (262 aa) |
| | ppk | Polyphosphate kinase 1 Ppk; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP); Belongs to the polyphosphate kinase 1 (PPK1) family. (733 aa) |
| | porB | Pyruvate ferredoxin oxidoreductase beta subunit PorB. (288 aa) |
| | fumA4 | Fumarate hydratase FumA4. (280 aa) |
| | Abm4_1459 | RNA-binding protein. (53 aa) |
| | thi4 | Thiazole biosynthesis enzyme; Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur. (262 aa) |
| | top6A | DNA topoisomerase VI subunit A; Relaxes both positive and negative superturns and exhibits a strong decatenase activity; Belongs to the TOP6A family. (371 aa) |
| | Abm4_1479 | Endonuclease IV. (277 aa) |
| | cofD | LPPG:FO 2-phospho-L-lactate transferase CofD; Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP. (303 aa) |
| | cofE2 | F420-0:gamma-glutamyl ligase CofE2; Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8- didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420- 0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives. (254 aa) |
| | rnhB | Ribonuclease HII RnhB; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (207 aa) |
| | ppsA | Phosphoenolpyruvate synthase PpsA; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (760 aa) |
| | pyrC | Dihydroorotase PyrC; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. (419 aa) |
| | mvhB | Methyl viologen-reducing hydrogenase beta subunit MvhB. (415 aa) |
| | mvhA | Methyl viologen-reducing hydrogenase alpha subunit MvhA; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. (474 aa) |
| | mvhD | Methyl viologen-reducing hydrogenase delta subunit MvhD. (139 aa) |
| | mtrA | Tetrahydromethanopterin S-methyltransferase subunit A MtrA; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step; Belongs to the MtrA family. (241 aa) |
| | mcrA | Methyl-coenzyme M reductase alpha subunit McrA; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis. (551 aa) |
| | Abm4_1531 | Methanogenesis marker protein 10. (423 aa) |
| | comB | 2-phosphosulfolactate phosphatase ComB. (232 aa) |
| | Abm4_1540 | Metallo-beta-lactamase superfamily protein. (271 aa) |
| | mptA | GTP cyclohydrolase MptA; Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin. (311 aa) |
| | cofG | FO synthase subunit 1 CofG; Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) from 5-amino-5-(4-hydroxybenzyl)-6-(D- ribitylimino)-5,6-dihydrouracil. (379 aa) |
| | hcp | Hydroxylamine reductase Hcp; Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O. (439 aa) |
| | pyrK | Dihydroorotate dehydrogenase electron transfer subunit PyrK. (265 aa) |
| | coaB | Phosphopantothenate-cysteine ligase CoaB. (219 aa) |
| | coaC | Phosphopantothenoylcysteine decarboxylase CoaC. (171 aa) |
| | Abm4_1564 | Hypothetical protein. (186 aa) |
| | queE | Radical SAM domain-containing protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (233 aa) |
| | Abm4_1570 | 6-pyruvoyl tetrahydropterin synthase/QueD family protein. (171 aa) |
| | Abm4_1573 | CRISPR-associated protein Cas4. (276 aa) |
| | ehbN | Energy-converting hydrogenase B subunit N EhbN. (378 aa) |
| | Abm4_1592 | Succinylglutamate desuccinylase/aspartoacylase. (257 aa) |
| | cobB | NAD-dependent protein deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription; Belongs to the sirtuin family. Class U subfamily. (245 aa) |
| | nnrE | Carbohydrate kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...] (519 aa) |
| | hjc | Archaeal Holliday junction resolvase Hjc; A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination. Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products; Belongs to the Holliday junction resolvase Hjc family. (136 aa) |
| | Abm4_1608 | Radical SAM domain-containing protein. (333 aa) |
| | hypF | Hydrogenase maturation factor HypF. (780 aa) |
| | dnaJ | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] (381 aa) |
| | Abm4_1629 | Iron-containing alcohol dehydrogenase. (393 aa) |
| | frhB1 | Coenzyme F420 hydrogenase beta subunit FrhB1. (292 aa) |
| | frhG | Coenzyme F420 hydrogenase gamma subunit FrhG. (271 aa) |
| | frhA | Coenzyme F420 hydrogenase alpha subunit FrhA; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. (405 aa) |
| | rps27e | Ribosomal protein S27e Rps27e. (59 aa) |
| | rpl44e | Ribosomal protein L44e Rpl44e; Binds to the 23S rRNA. (92 aa) |
| | tfs2 | Transcription factor S Tfs2; Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (105 aa) |
| | csl4 | Exosome complex RNA-binding protein Csl4; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs. (189 aa) |
| | Abm4_1653 | Diphthamide biosynthesis protein; Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L- methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2). Belongs to the DPH1/DPH2 family. (336 aa) |
| | fprA2 | F420H2 oxidase FprA2. (411 aa) |
| | Abm4_1681 | Rubrerythrin. (137 aa) |
| | purL | Phosphoribosylformylglycinamidine (FGAM) synthase II PurL; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is though [...] (718 aa) |
| | ileS | isoleucyl-tRNA synthetase IleS; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1107 aa) |
| | metK | S-adenosylmethionine synthetase MetK; Catalyzes the formation of S-adenosylmethionine from methionine and ATP; Belongs to the AdoMet synthase 2 family. (401 aa) |
| | hdrA2 | CoB--CoM heterodisulfide reductase subunit A HdrA2; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). (660 aa) |
| | leuB | 3-isopropylmalate dehydrogenase LeuB. (329 aa) |
| | leuC | 3-isopropylmalate dehydratase large subunit LeuC; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (415 aa) |
| | Abm4_1724 | Glycyl-radical enzyme activating protein family. (335 aa) |
| | Abm4_1729 | Hypothetical protein. (215 aa) |
| | thiL | Thiamine monphosphate kinase ThiL; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (344 aa) |
| | hisG | ATP phosphoribosyltransferase HisG; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (288 aa) |
| | hcgA | BioB family protein HcgA. (333 aa) |
| | hgcD | NIF3 family protein HcgD. (234 aa) |
| | dadD | Amidohydrolase; Catalyzes the deamination of three SAM-derived enzymatic products, namely 5'-deoxyadenosine, S-adenosyl-L-homocysteine, and 5'- methylthioadenosine, to produce the inosine analogs. Can also deaminate adenosine. The preferred substrate for this enzyme is 5'- deoxyadenosine, but all these substrates are efficiently deaminated. Likely functions in a S-adenosyl-L-methionine (SAM) recycling pathway from S-adenosyl-L-homocysteine (SAH) produced from SAM-dependent methylation reactions. May also be involved in the recycling of 5'- deoxyadenosine, whereupon the 5'-deoxyribose m [...] (442 aa) |
| | ribB | 3,4-dihydroxy-2-butanone 4-phosphate synthase RibB; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. (212 aa) |
| | ribK | Riboflavin kinase RibK; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family. (126 aa) |
| | nudC | NADH pyrophosphatase NudC. (267 aa) |
| | Abm4_0035 | Radical SAM domain-containing protein. (371 aa) |
| | thrS | threonyl-tRNA synthetase ThrS; Belongs to the class-II aminoacyl-tRNA synthetase family. (611 aa) |
| | ilvD | Dihydroxy-acid dehydratase IlvD; Belongs to the IlvD/Edd family. (551 aa) |
| | purD | Phosphoribosylamine-glycine ligase PurD; Belongs to the GARS family. (437 aa) |
| | ilvB1 | Acetolactate synthase large subunit IlvB1. (566 aa) |
| | ilvC | Ketol-acid reductoisomerase IlvC; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (331 aa) |
| | surE | 5'/3'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (264 aa) |
| | Abm4_0080 | Universal archaeal protein Kae1; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / TsaD family. (549 aa) |
| | Abm4_0081 | RdgB/HAM1 family non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (185 aa) |
| | Abm4_0089 | Hypothetical protein. (168 aa) |
| | Abm4_0091 | Hypothetical protein. (389 aa) |
| | cas2 | CRISPR-associated endoribonuclease Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (87 aa) |
| | cas1 | CRISPR-associated endonuclease Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (322 aa) |
| | Abm4_0107 | CRISPR-associated protein Cas4; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Belongs to the CRISPR-associated exonuclease Cas4 family. (164 aa) |
| | Abm4_0108 | CRISPR-associated helicase Cas3. (948 aa) |
| | nadE | NAD+ synthetase NadE; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. (270 aa) |
| | Abm4_0128 | Copper ion-binding protein. (70 aa) |
| | Abm4_0129 | Copper translocating P-type ATPase. (818 aa) |
| | fdhA | Formate dehydrogenase alpha subunit FdhA. (688 aa) |
| | fdhB | Formate dehydrogenase beta subunit FdhB. (411 aa) |
| | moaA | Molybdopterin cofactor biosynthesis protein A MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family. (310 aa) |
| | mobB | Molybdopterin-guanine dinucleotide biosynthesis protein B MobB. (234 aa) |
| | fwdC | Tungsten formylmethanofuran dehydrogenase subunit C FwdC. (288 aa) |
| | fwdE | Tungsten formylmethanofuran dehydrogenase subunit E FwdE. (190 aa) |
| | thiC1 | Thiamine biosynthesis protein ThiC1; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. (434 aa) |
| | Abm4_0158 | CMP/dCMP deaminase. (157 aa) |
| | fen | Flap endonuclease Fen; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. [...] (327 aa) |
| | aksD | Homoaconitase large subunit AksD; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (415 aa) |
| | serB | Phosphoserine phosphatase SerB. (499 aa) |
| | Abm4_0186 | Oligosaccharyl transferase. (906 aa) |
| | rnp4 | Ribonuclease P subunit RPR2; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. (123 aa) |
| | ilvB2 | Acetolactate synthase large subunit IlvB2; Belongs to the TPP enzyme family. (538 aa) |
| | mptE | Hypothetical protein; Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl- 7,8-dihydropterin diphosphate (6-HMDP); Belongs to the archaeal 6-HMPDK family. (242 aa) |
| | Abm4_0215 | Hypothetical protein; Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently. (154 aa) |
| | rtcB | Hypothetical protein; Belongs to the RtcB family. (482 aa) |
| | Abm4_0223 | Rubredoxin; Rubredoxin is a small nonheme, iron protein lacking acid- labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule. (62 aa) |
| | apgM | 2,3-bisphosphoglycerate-independent phosphoglycerate mutase ApgM; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (412 aa) |
| | glmM1 | Phosphoglucosamine mutase GlmM1; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. (450 aa) |
| | Abm4_0229 | Anaerobic ribonucleoside-triphosphate reductase activating protein. (236 aa) |
| | Abm4_0231 | Hypothetical protein. (200 aa) |
| | glmM2 | Phosphoglucosamine mutase GlmM2; Belongs to the phosphohexose mutase family. (454 aa) |
| | dnlI | ATP-dependent DNA ligase DnlI; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. (550 aa) |
| | thiC2 | Thiamine biosynthesis protein ThiC2; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. (424 aa) |
| | pelA | Cell division protein pelota PelA; May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity. (353 aa) |
| | Abm4_0242 | Hypothetical protein. (340 aa) |
| | hypC | Hydrogenase assembly chaperone HypC. (89 aa) |
| | Abm4_0248 | Hypothetical protein. (95 aa) |
| | alaS | alanyl-tRNA synthetase AlaS; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (906 aa) |
| | fbp | Fructose 1,6-bisphosphatase Fbp; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P). (365 aa) |
| | Abm4_0270 | Archaetidylinositol synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (352 aa) |
| | gph | Phosphoglycolate phosphatase Gph; Catalyzes the dephosphorylation of 2-phosphoglycolate. (231 aa) |
| | hypD | Hydrogenase expression/formation protein HypD. (348 aa) |
| | modA | Molybdate ABC transporter substrate-binding protein ModA. (270 aa) |
| | Abm4_0306 | Digeranylgeranylglyceryl phosphate synthase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids. (284 aa) |
| | Abm4_0314 | Hypothetical protein. (130 aa) |
| | queC | ExsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. (226 aa) |
| | Abm4_0319 | Hypothetical protein; Belongs to the LarC family. (406 aa) |
| | sucC | succinyl-CoA synthetase beta subunit SucC; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (369 aa) |
| | taw1 | tRNA-modifying enzyme; Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe). (306 aa) |
| | thiE | Thiamine monophosphate synthase ThiE; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (208 aa) |
| | thiM | Hydroxyethylthiazole kinase ThiM; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. (291 aa) |
| | rpoB | DNA-directed RNA polymerase subunit B RpoB; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1117 aa) |
| | Abm4_0369 | Hypothetical protein. (272 aa) |
| | Abm4_0370 | Hypothetical protein. (440 aa) |
| | Abm4_0374 | Hypothetical protein. (425 aa) |
| | carB | Carbamoylphosphate synthase large subunit CarB; Belongs to the CarB family. (1065 aa) |
| | Abm4_0391 | Hypothetical protein. (126 aa) |
| | Abm4_0399 | Peptidase M50 family. (209 aa) |
| | thgL | tRNA(His) guanylyltransferase ThgL. (282 aa) |
| | Abm4_0408 | Hypothetical protein. (272 aa) |
