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Abm4_1608 Abm4_1608 queE queE hcp hcp cofG cofG mvhB mvhB fumA4 fumA4 porB porB porD porD Abm4_1419 Abm4_1419 Abm4_1418 Abm4_1418 nadA nadA iorA iorA hdrC2 hdrC2 Abm4_1065 Abm4_1065 gltA gltA fdhA2 fdhA2 cofH cofH Abm4_1653 Abm4_1653 hdrA2 hdrA2 leuC leuC Abm4_1724 Abm4_1724 purF purF hdrA1 hdrA1 priB priB Abm4_0530 Abm4_0530 Abm4_0525 Abm4_0525 Abm4_0510 Abm4_0510 fumA2 fumA2 taw1 taw1 thiC2 thiC2 aksD aksD thiC1 thiC1 mobB mobB moaA moaA fdhB fdhB Abm4_0733 Abm4_0733 fdhA fdhA hcgA hcgA
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
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Abm4_1608Radical SAM domain-containing protein. (333 aa)
queERadical SAM domain-containing protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (233 aa)
hcpHydroxylamine reductase Hcp; Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O. (439 aa)
cofGFO synthase subunit 1 CofG; Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) from 5-amino-5-(4-hydroxybenzyl)-6-(D- ribitylimino)-5,6-dihydrouracil. (379 aa)
mvhBMethyl viologen-reducing hydrogenase beta subunit MvhB. (415 aa)
fumA4Fumarate hydratase FumA4. (280 aa)
porBPyruvate ferredoxin oxidoreductase beta subunit PorB. (288 aa)
porDPyruvate ferredoxin oxidoreductase delta subunit PorD. (82 aa)
Abm4_1419Radical SAM domain-containing protein. (364 aa)
Abm4_1418Radical SAM domain-containing protein. (304 aa)
nadAQuinolinate synthetase A protein NadA; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (304 aa)
iorAIndolepyruvate ferredoxin oxidoreductase alpha subunit IorA; Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates. (634 aa)
hdrC2CoB--CoM heterodisulfide reductase subunit C HdrC2. (347 aa)
Abm4_1065Radical SAM domain-containing protein. (298 aa)
gltAGlutamate synthase alpha subunit GltA; Belongs to the glutamate synthase family. (497 aa)
fdhA2Formate dehydrogenase alpha subunit FdhA2. (343 aa)
cofHFO synthase subunit 2 CofH; Catalyzes the radical-mediated synthesis of 5-amino-5-(4- hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil from 5-amino-6-(D- ribitylamino)uracil and L-tyrosine. (374 aa)
Abm4_1653Diphthamide biosynthesis protein; Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L- methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2). Belongs to the DPH1/DPH2 family. (336 aa)
hdrA2CoB--CoM heterodisulfide reductase subunit A HdrA2; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). (660 aa)
leuC3-isopropylmalate dehydratase large subunit LeuC; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (415 aa)
Abm4_1724Glycyl-radical enzyme activating protein family. (335 aa)
purFAmidophosphoribosyltransferase PurF; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (469 aa)
hdrA1CoB--CoM heterodisulfide reductase subunit A HdrA1; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). (776 aa)
priBDNA primase large subunit PriB; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair. (452 aa)
Abm4_0530Histone acetyltransferase ELP3 family. (570 aa)
Abm4_0525MiaB-like tRNA modifying enzyme. (429 aa)
Abm4_0510Molybdenum cofactor biosynthesis-related protein. (509 aa)
fumA2Fumarate hydratase FumA2. (293 aa)
taw1tRNA-modifying enzyme; Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe). (306 aa)
thiC2Thiamine biosynthesis protein ThiC2; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. (424 aa)
aksDHomoaconitase large subunit AksD; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (415 aa)
thiC1Thiamine biosynthesis protein ThiC1; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. (434 aa)
mobBMolybdopterin-guanine dinucleotide biosynthesis protein B MobB. (234 aa)
moaAMolybdopterin cofactor biosynthesis protein A MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family. (310 aa)
fdhBFormate dehydrogenase beta subunit FdhB. (411 aa)
Abm4_07334Fe-4S iron sulfur cluster binding protein NifH/frxC family; Belongs to the NifH/BchL/ChlL family. (267 aa)
fdhAFormate dehydrogenase alpha subunit FdhA. (688 aa)
hcgABioB family protein HcgA. (333 aa)
Your Current Organism:
Methanobrevibacter sp. AbM4
NCBI taxonomy Id: 224719
Other names: M. sp. AbM4
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