(6 nodes) Ribosomal protein L2, domain 2 network (Methanobrevibacter sp. AbM4)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	spt5	Ribosomal protein L24 family; Stimulates transcription elongation; Belongs to the archaeal Spt5 family. (160 aa)
	eif5a	Translation initiation factor eIF-5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family. (135 aa)
	Abm4_1248	Ribosomal protein L14e Rpl14e. (73 aa)
	rps4e	Ribosomal protein S4e Rps4e; Belongs to the eukaryotic ribosomal protein eS4 family. (241 aa)
	rpl24	Ribosomal protein L24P Rpl24p; Located at the polypeptide exit tunnel on the outside of the subunit. (116 aa)
	rpl2p	Ribosomal protein L2P Rpl2p; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (241 aa)

Your Current Organism:

Methanobrevibacter sp. AbM4

NCBI taxonomy Id: 224719
Other names: M. sp. AbM4

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Abm4_1248	eif5a	Abm4_1248	Abm4_0463	Ribosomal protein L14e Rpl14e.	Translation initiation factor eIF-5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family.	0.951
Abm4_1248	rpl24	Abm4_1248	Abm4_1265	Ribosomal protein L14e Rpl14e.	Ribosomal protein L24P Rpl24p; Located at the polypeptide exit tunnel on the outside of the subunit.	0.999
Abm4_1248	rpl2p	Abm4_1248	Abm4_1274	Ribosomal protein L14e Rpl14e.	Ribosomal protein L2P Rpl2p; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	0.999
Abm4_1248	rps4e	Abm4_1248	Abm4_1264	Ribosomal protein L14e Rpl14e.	Ribosomal protein S4e Rps4e; Belongs to the eukaryotic ribosomal protein eS4 family.	0.999
eif5a	Abm4_1248	Abm4_0463	Abm4_1248	Translation initiation factor eIF-5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family.	Ribosomal protein L14e Rpl14e.	0.951
eif5a	rpl24	Abm4_0463	Abm4_1265	Translation initiation factor eIF-5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family.	Ribosomal protein L24P Rpl24p; Located at the polypeptide exit tunnel on the outside of the subunit.	0.982
eif5a	rpl2p	Abm4_0463	Abm4_1274	Translation initiation factor eIF-5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family.	Ribosomal protein L2P Rpl2p; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	0.975
eif5a	rps4e	Abm4_0463	Abm4_1264	Translation initiation factor eIF-5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family.	Ribosomal protein S4e Rps4e; Belongs to the eukaryotic ribosomal protein eS4 family.	0.989
eif5a	spt5	Abm4_0463	Abm4_0255	Translation initiation factor eIF-5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family.	Ribosomal protein L24 family; Stimulates transcription elongation; Belongs to the archaeal Spt5 family.	0.844
rpl24	Abm4_1248	Abm4_1265	Abm4_1248	Ribosomal protein L24P Rpl24p; Located at the polypeptide exit tunnel on the outside of the subunit.	Ribosomal protein L14e Rpl14e.	0.999
rpl24	eif5a	Abm4_1265	Abm4_0463	Ribosomal protein L24P Rpl24p; Located at the polypeptide exit tunnel on the outside of the subunit.	Translation initiation factor eIF-5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family.	0.982
rpl24	rpl2p	Abm4_1265	Abm4_1274	Ribosomal protein L24P Rpl24p; Located at the polypeptide exit tunnel on the outside of the subunit.	Ribosomal protein L2P Rpl2p; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	0.999
rpl24	rps4e	Abm4_1265	Abm4_1264	Ribosomal protein L24P Rpl24p; Located at the polypeptide exit tunnel on the outside of the subunit.	Ribosomal protein S4e Rps4e; Belongs to the eukaryotic ribosomal protein eS4 family.	0.999
rpl24	spt5	Abm4_1265	Abm4_0255	Ribosomal protein L24P Rpl24p; Located at the polypeptide exit tunnel on the outside of the subunit.	Ribosomal protein L24 family; Stimulates transcription elongation; Belongs to the archaeal Spt5 family.	0.986
rpl2p	Abm4_1248	Abm4_1274	Abm4_1248	Ribosomal protein L2P Rpl2p; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	Ribosomal protein L14e Rpl14e.	0.999
rpl2p	eif5a	Abm4_1274	Abm4_0463	Ribosomal protein L2P Rpl2p; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	Translation initiation factor eIF-5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family.	0.975
rpl2p	rpl24	Abm4_1274	Abm4_1265	Ribosomal protein L2P Rpl2p; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	Ribosomal protein L24P Rpl24p; Located at the polypeptide exit tunnel on the outside of the subunit.	0.999
rpl2p	rps4e	Abm4_1274	Abm4_1264	Ribosomal protein L2P Rpl2p; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	Ribosomal protein S4e Rps4e; Belongs to the eukaryotic ribosomal protein eS4 family.	0.999
rpl2p	spt5	Abm4_1274	Abm4_0255	Ribosomal protein L2P Rpl2p; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	Ribosomal protein L24 family; Stimulates transcription elongation; Belongs to the archaeal Spt5 family.	0.969
rps4e	Abm4_1248	Abm4_1264	Abm4_1248	Ribosomal protein S4e Rps4e; Belongs to the eukaryotic ribosomal protein eS4 family.	Ribosomal protein L14e Rpl14e.	0.999