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valS valS gltX gltX coaD coaD tyrS tyrS Abm4_1424 Abm4_1424 Abm4_1507 Abm4_1507 Abm4_1541 Abm4_1541 argG argG ileS ileS thiI thiI queC queC Abm4_0198 Abm4_0198 lysS lysS nadE nadE leuS leuS argS argS Abm4_0771 Abm4_0771 uspA2 uspA2 Abm4_0725 Abm4_0725 asnB asnB uspA1 uspA1 Abm4_0818 Abm4_0818 guaAb guaAb Abm4_0396 Abm4_0396 ribL ribL metG metG trpS trpS uspA3 uspA3 cysS cysS
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
valSvalyl-tRNA synthetase ValS; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily. (909 aa)
gltXglutamyl-tRNA synthetase GltX; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (557 aa)
coaDPhosphopantetheine adenylyltransferase CoaD. (151 aa)
tyrStyrosyl-tRNA synthetase TyrS; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 3 subfamily. (320 aa)
Abm4_1424PP-loop family protein. (310 aa)
Abm4_1507Hypothetical protein. (379 aa)
Abm4_1541PP-loop family protein. (285 aa)
argGArgininosuccinate synthase ArgG; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (391 aa)
ileSisoleucyl-tRNA synthetase IleS; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1107 aa)
thiIThiamine biosynthesis ATP pyrophosphatase ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (382 aa)
queCExsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. (226 aa)
Abm4_0198tRNA methyltransferase subunit. (194 aa)
lysSlysyl-tRNA synthetase LysS; Belongs to the class-I aminoacyl-tRNA synthetase family. (528 aa)
nadENAD+ synthetase NadE; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. (270 aa)
leuSleucyl-tRNA synthetase LeuS; Belongs to the class-I aminoacyl-tRNA synthetase family. (955 aa)
argSarginyl-tRNA synthetase ArgS; Belongs to the class-I aminoacyl-tRNA synthetase family. (574 aa)
Abm4_0771Nicotinamide-nucleotide adenylyltransferase. (178 aa)
uspA2Universal stress protein UspA2. (134 aa)
Abm4_0725Hypothetical protein. (355 aa)
asnBAsparagine synthase (glutamine-hydrolyzing) AsnB. (516 aa)
uspA1Universal stress protein UspA1. (143 aa)
Abm4_0818ATP-binding protein. (227 aa)
guaAbGMP synthase subunit B GuaAb; Catalyzes the synthesis of GMP from XMP. (308 aa)
Abm4_0396PP-loop family protein. (350 aa)
ribLFAD synthetase RibL; Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme. (152 aa)
metGmethionyl-tRNA synthetase MetG; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (671 aa)
trpStryptophanyl-tRNA synthetase TrpS; Catalyzes the attachment of tryptophan to tRNA(Trp). (363 aa)
uspA3Universal stress protein UspA3. (141 aa)
cysScysteinyl-tRNA synthetase CysS; Belongs to the class-I aminoacyl-tRNA synthetase family. (487 aa)
Your Current Organism:
Methanobrevibacter sp. AbM4
NCBI taxonomy Id: 224719
Other names: M. sp. AbM4
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