(15 nodes) Biotin/lipoyl attachment network (Bradyrhizobium diazoefficiens)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	pdhB	Pyruvate dehydrogenase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (463 aa)
	mccA	3-methylcrotonyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (658 aa)
	AND88991.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (141 aa)
	AND94002.1	Hypothetical protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (148 aa)
	aceF	Dihydrolipoamide acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (522 aa)
	lpd	Dihydrolipoamide dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (581 aa)
	AND89250.1	Biotin attachment protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (73 aa)
	accB	acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (161 aa)
	mccA-2	3-methylcrotonyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (671 aa)
	AND90027.1	Branched-chain alpha-keto acid dehydrogenase subunit E2; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (451 aa)
	pccA	acetyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (671 aa)
	gcvH	Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (122 aa)
	bkdB	Branched-chain alpha-keto acid dehydrogenase subunit E2; Derived by automated computational analysis using gene prediction method: Protein Homology. (427 aa)
	AND92261.1	Carbamoyl-phosphate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (1101 aa)
	sucB	Dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (414 aa)

Your Current Organism:

Bradyrhizobium diazoefficiens

NCBI taxonomy Id: 224911
Other names: B. diazoefficiens USDA 110, Bradyrhizobium diazoefficiens USDA 110, Bradyrhizobium japonicum USDA 110

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AND88991.1	AND92261.1	AAV28_15185	AAV28_34120	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Carbamoyl-phosphate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.555
AND88991.1	AND94002.1	AAV28_15185	AAV28_15205	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.	0.985
AND88991.1	mccA	AAV28_15185	AAV28_01780	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	3-methylcrotonyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.818
AND88991.1	mccA-2	AAV28_15185	AAV28_19250	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	3-methylcrotonyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.818
AND88991.1	pccA	AAV28_15185	AAV28_23715	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	acetyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.818
AND89250.1	AND92261.1	AAV28_16705	AAV28_34120	Biotin attachment protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Carbamoyl-phosphate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.555
AND89250.1	mccA	AAV28_16705	AAV28_01780	Biotin attachment protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	3-methylcrotonyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.817
AND89250.1	mccA-2	AAV28_16705	AAV28_19250	Biotin attachment protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	3-methylcrotonyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.817
AND89250.1	pccA	AAV28_16705	AAV28_23715	Biotin attachment protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	acetyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.817
AND90027.1	AND92261.1	AAV28_21190	AAV28_34120	Branched-chain alpha-keto acid dehydrogenase subunit E2; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	Carbamoyl-phosphate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.402
AND90027.1	AND94002.1	AAV28_21190	AAV28_15205	Branched-chain alpha-keto acid dehydrogenase subunit E2; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	Hypothetical protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.	0.916
AND90027.1	accB	AAV28_21190	AAV28_18515	Branched-chain alpha-keto acid dehydrogenase subunit E2; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.	0.912
AND90027.1	aceF	AAV28_21190	AAV28_15575	Branched-chain alpha-keto acid dehydrogenase subunit E2; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	Dihydrolipoamide acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.921
AND90027.1	gcvH	AAV28_21190	AAV28_26270	Branched-chain alpha-keto acid dehydrogenase subunit E2; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.	0.718
AND90027.1	lpd	AAV28_21190	AAV28_15580	Branched-chain alpha-keto acid dehydrogenase subunit E2; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	Dihydrolipoamide dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.991
AND90027.1	pdhB	AAV28_21190	AAV28_21205	Branched-chain alpha-keto acid dehydrogenase subunit E2; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	Pyruvate dehydrogenase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	0.998
AND92261.1	AND88991.1	AAV28_34120	AAV28_15185	Carbamoyl-phosphate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.555
AND92261.1	AND89250.1	AAV28_34120	AAV28_16705	Carbamoyl-phosphate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.	Biotin attachment protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.555
AND92261.1	AND90027.1	AAV28_34120	AAV28_21190	Carbamoyl-phosphate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.	Branched-chain alpha-keto acid dehydrogenase subunit E2; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	0.402
AND92261.1	AND94002.1	AAV28_34120	AAV28_15205	Carbamoyl-phosphate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.	0.798