node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Sps_00694 | Sps_01657 | Sps_00694 | Sps_01657 | PFAM: Serine dehydratase alpha chain; Serine dehydratase beta chain; 'TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, single chain form'. | L-serine ammonia-lyase; PFAM: Serine dehydratase alpha chain; Serine dehydratase beta chain; 'TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, single chain form'. | 0.903 |
Sps_00694 | Sps_02652 | Sps_00694 | Sps_02652 | PFAM: Serine dehydratase alpha chain; Serine dehydratase beta chain; 'TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, single chain form'. | L-serine ammonia-lyase; PFAM: Serine dehydratase alpha chain; Serine dehydratase beta chain; 'TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, single chain form'. | 0.905 |
Sps_00694 | Sps_04230 | Sps_00694 | Sps_04230 | PFAM: Serine dehydratase alpha chain; Serine dehydratase beta chain; 'TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, single chain form'. | Phosphoserine phosphatase; PFAM: haloacid dehalogenase-like hydrolase; 'TIGRFAM: Haloacid Dehalogenase superfamily, subfamily IB, phosphoserine phosphatase-like; phosphoserine phosphatase SerB'. | 0.908 |
Sps_00694 | glyA | Sps_00694 | Sps_00695 | PFAM: Serine dehydratase alpha chain; Serine dehydratase beta chain; 'TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, single chain form'. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.984 |
Sps_01657 | Sps_00694 | Sps_01657 | Sps_00694 | L-serine ammonia-lyase; PFAM: Serine dehydratase alpha chain; Serine dehydratase beta chain; 'TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, single chain form'. | PFAM: Serine dehydratase alpha chain; Serine dehydratase beta chain; 'TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, single chain form'. | 0.903 |
Sps_01657 | Sps_02652 | Sps_01657 | Sps_02652 | L-serine ammonia-lyase; PFAM: Serine dehydratase alpha chain; Serine dehydratase beta chain; 'TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, single chain form'. | L-serine ammonia-lyase; PFAM: Serine dehydratase alpha chain; Serine dehydratase beta chain; 'TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, single chain form'. | 0.903 |
Sps_01657 | Sps_04230 | Sps_01657 | Sps_04230 | L-serine ammonia-lyase; PFAM: Serine dehydratase alpha chain; Serine dehydratase beta chain; 'TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, single chain form'. | Phosphoserine phosphatase; PFAM: haloacid dehalogenase-like hydrolase; 'TIGRFAM: Haloacid Dehalogenase superfamily, subfamily IB, phosphoserine phosphatase-like; phosphoserine phosphatase SerB'. | 0.908 |
Sps_01657 | glyA | Sps_01657 | Sps_00695 | L-serine ammonia-lyase; PFAM: Serine dehydratase alpha chain; Serine dehydratase beta chain; 'TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, single chain form'. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.946 |
Sps_02652 | Sps_00694 | Sps_02652 | Sps_00694 | L-serine ammonia-lyase; PFAM: Serine dehydratase alpha chain; Serine dehydratase beta chain; 'TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, single chain form'. | PFAM: Serine dehydratase alpha chain; Serine dehydratase beta chain; 'TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, single chain form'. | 0.905 |
Sps_02652 | Sps_01657 | Sps_02652 | Sps_01657 | L-serine ammonia-lyase; PFAM: Serine dehydratase alpha chain; Serine dehydratase beta chain; 'TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, single chain form'. | L-serine ammonia-lyase; PFAM: Serine dehydratase alpha chain; Serine dehydratase beta chain; 'TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, single chain form'. | 0.903 |
Sps_02652 | Sps_04230 | Sps_02652 | Sps_04230 | L-serine ammonia-lyase; PFAM: Serine dehydratase alpha chain; Serine dehydratase beta chain; 'TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, single chain form'. | Phosphoserine phosphatase; PFAM: haloacid dehalogenase-like hydrolase; 'TIGRFAM: Haloacid Dehalogenase superfamily, subfamily IB, phosphoserine phosphatase-like; phosphoserine phosphatase SerB'. | 0.908 |
Sps_02652 | glyA | Sps_02652 | Sps_00695 | L-serine ammonia-lyase; PFAM: Serine dehydratase alpha chain; Serine dehydratase beta chain; 'TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, single chain form'. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.946 |
Sps_04230 | Sps_00694 | Sps_04230 | Sps_00694 | Phosphoserine phosphatase; PFAM: haloacid dehalogenase-like hydrolase; 'TIGRFAM: Haloacid Dehalogenase superfamily, subfamily IB, phosphoserine phosphatase-like; phosphoserine phosphatase SerB'. | PFAM: Serine dehydratase alpha chain; Serine dehydratase beta chain; 'TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, single chain form'. | 0.908 |
Sps_04230 | Sps_01657 | Sps_04230 | Sps_01657 | Phosphoserine phosphatase; PFAM: haloacid dehalogenase-like hydrolase; 'TIGRFAM: Haloacid Dehalogenase superfamily, subfamily IB, phosphoserine phosphatase-like; phosphoserine phosphatase SerB'. | L-serine ammonia-lyase; PFAM: Serine dehydratase alpha chain; Serine dehydratase beta chain; 'TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, single chain form'. | 0.908 |
Sps_04230 | Sps_02652 | Sps_04230 | Sps_02652 | Phosphoserine phosphatase; PFAM: haloacid dehalogenase-like hydrolase; 'TIGRFAM: Haloacid Dehalogenase superfamily, subfamily IB, phosphoserine phosphatase-like; phosphoserine phosphatase SerB'. | L-serine ammonia-lyase; PFAM: Serine dehydratase alpha chain; Serine dehydratase beta chain; 'TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, single chain form'. | 0.908 |
Sps_04230 | glyA | Sps_04230 | Sps_00695 | Phosphoserine phosphatase; PFAM: haloacid dehalogenase-like hydrolase; 'TIGRFAM: Haloacid Dehalogenase superfamily, subfamily IB, phosphoserine phosphatase-like; phosphoserine phosphatase SerB'. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.926 |
glyA | Sps_00694 | Sps_00695 | Sps_00694 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | PFAM: Serine dehydratase alpha chain; Serine dehydratase beta chain; 'TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, single chain form'. | 0.984 |
glyA | Sps_01657 | Sps_00695 | Sps_01657 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | L-serine ammonia-lyase; PFAM: Serine dehydratase alpha chain; Serine dehydratase beta chain; 'TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, single chain form'. | 0.946 |
glyA | Sps_02652 | Sps_00695 | Sps_02652 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | L-serine ammonia-lyase; PFAM: Serine dehydratase alpha chain; Serine dehydratase beta chain; 'TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, single chain form'. | 0.946 |
glyA | Sps_04230 | Sps_00695 | Sps_04230 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Phosphoserine phosphatase; PFAM: haloacid dehalogenase-like hydrolase; 'TIGRFAM: Haloacid Dehalogenase superfamily, subfamily IB, phosphoserine phosphatase-like; phosphoserine phosphatase SerB'. | 0.926 |