node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Sps_00575 | Sps_01137 | Sps_00575 | Sps_01137 | Cystathionine beta-lyase; PFAM: Cys/Met metabolism PLP-dependent enzyme; 'TIGRFAM: cystathionine beta-lyase, bacterial'. | Cysteine synthase; PFAM: Pyridoxal-phosphate dependent enzyme. | 0.963 |
Sps_00575 | Sps_02954 | Sps_00575 | Sps_02954 | Cystathionine beta-lyase; PFAM: Cys/Met metabolism PLP-dependent enzyme; 'TIGRFAM: cystathionine beta-lyase, bacterial'. | PFAM: Methylenetetrahydrofolate reductase; 'TIGRFAM: 5,10-methylenetetrahydrofolate reductase, prokaryotic form'; Belongs to the methylenetetrahydrofolate reductase family. | 0.728 |
Sps_00575 | Sps_02956 | Sps_00575 | Sps_02956 | Cystathionine beta-lyase; PFAM: Cys/Met metabolism PLP-dependent enzyme; 'TIGRFAM: cystathionine beta-lyase, bacterial'. | Cystathionine gamma-synthase; PFAM: Cys/Met metabolism PLP-dependent enzyme; TIGRFAM: O-succinylhomoserine (thiol)-lyase. | 0.935 |
Sps_00575 | Sps_04796 | Sps_00575 | Sps_04796 | Cystathionine beta-lyase; PFAM: Cys/Met metabolism PLP-dependent enzyme; 'TIGRFAM: cystathionine beta-lyase, bacterial'. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.978 |
Sps_00575 | metAS | Sps_00575 | Sps_02050 | Cystathionine beta-lyase; PFAM: Cys/Met metabolism PLP-dependent enzyme; 'TIGRFAM: cystathionine beta-lyase, bacterial'. | Homoserine O-succinyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine; Belongs to the MetA family. | 0.735 |
Sps_01137 | Sps_00575 | Sps_01137 | Sps_00575 | Cysteine synthase; PFAM: Pyridoxal-phosphate dependent enzyme. | Cystathionine beta-lyase; PFAM: Cys/Met metabolism PLP-dependent enzyme; 'TIGRFAM: cystathionine beta-lyase, bacterial'. | 0.963 |
Sps_01137 | Sps_02956 | Sps_01137 | Sps_02956 | Cysteine synthase; PFAM: Pyridoxal-phosphate dependent enzyme. | Cystathionine gamma-synthase; PFAM: Cys/Met metabolism PLP-dependent enzyme; TIGRFAM: O-succinylhomoserine (thiol)-lyase. | 0.965 |
Sps_01137 | Sps_04796 | Sps_01137 | Sps_04796 | Cysteine synthase; PFAM: Pyridoxal-phosphate dependent enzyme. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.883 |
Sps_02954 | Sps_00575 | Sps_02954 | Sps_00575 | PFAM: Methylenetetrahydrofolate reductase; 'TIGRFAM: 5,10-methylenetetrahydrofolate reductase, prokaryotic form'; Belongs to the methylenetetrahydrofolate reductase family. | Cystathionine beta-lyase; PFAM: Cys/Met metabolism PLP-dependent enzyme; 'TIGRFAM: cystathionine beta-lyase, bacterial'. | 0.728 |
Sps_02954 | Sps_02956 | Sps_02954 | Sps_02956 | PFAM: Methylenetetrahydrofolate reductase; 'TIGRFAM: 5,10-methylenetetrahydrofolate reductase, prokaryotic form'; Belongs to the methylenetetrahydrofolate reductase family. | Cystathionine gamma-synthase; PFAM: Cys/Met metabolism PLP-dependent enzyme; TIGRFAM: O-succinylhomoserine (thiol)-lyase. | 0.823 |
Sps_02954 | Sps_04796 | Sps_02954 | Sps_04796 | PFAM: Methylenetetrahydrofolate reductase; 'TIGRFAM: 5,10-methylenetetrahydrofolate reductase, prokaryotic form'; Belongs to the methylenetetrahydrofolate reductase family. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.995 |
Sps_02954 | metAS | Sps_02954 | Sps_02050 | PFAM: Methylenetetrahydrofolate reductase; 'TIGRFAM: 5,10-methylenetetrahydrofolate reductase, prokaryotic form'; Belongs to the methylenetetrahydrofolate reductase family. | Homoserine O-succinyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine; Belongs to the MetA family. | 0.887 |
Sps_02956 | Sps_00575 | Sps_02956 | Sps_00575 | Cystathionine gamma-synthase; PFAM: Cys/Met metabolism PLP-dependent enzyme; TIGRFAM: O-succinylhomoserine (thiol)-lyase. | Cystathionine beta-lyase; PFAM: Cys/Met metabolism PLP-dependent enzyme; 'TIGRFAM: cystathionine beta-lyase, bacterial'. | 0.935 |
Sps_02956 | Sps_01137 | Sps_02956 | Sps_01137 | Cystathionine gamma-synthase; PFAM: Cys/Met metabolism PLP-dependent enzyme; TIGRFAM: O-succinylhomoserine (thiol)-lyase. | Cysteine synthase; PFAM: Pyridoxal-phosphate dependent enzyme. | 0.965 |
Sps_02956 | Sps_02954 | Sps_02956 | Sps_02954 | Cystathionine gamma-synthase; PFAM: Cys/Met metabolism PLP-dependent enzyme; TIGRFAM: O-succinylhomoserine (thiol)-lyase. | PFAM: Methylenetetrahydrofolate reductase; 'TIGRFAM: 5,10-methylenetetrahydrofolate reductase, prokaryotic form'; Belongs to the methylenetetrahydrofolate reductase family. | 0.823 |
Sps_02956 | Sps_04796 | Sps_02956 | Sps_04796 | Cystathionine gamma-synthase; PFAM: Cys/Met metabolism PLP-dependent enzyme; TIGRFAM: O-succinylhomoserine (thiol)-lyase. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.978 |
Sps_02956 | metAS | Sps_02956 | Sps_02050 | Cystathionine gamma-synthase; PFAM: Cys/Met metabolism PLP-dependent enzyme; TIGRFAM: O-succinylhomoserine (thiol)-lyase. | Homoserine O-succinyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine; Belongs to the MetA family. | 0.975 |
Sps_04796 | Sps_00575 | Sps_04796 | Sps_00575 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Cystathionine beta-lyase; PFAM: Cys/Met metabolism PLP-dependent enzyme; 'TIGRFAM: cystathionine beta-lyase, bacterial'. | 0.978 |
Sps_04796 | Sps_01137 | Sps_04796 | Sps_01137 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Cysteine synthase; PFAM: Pyridoxal-phosphate dependent enzyme. | 0.883 |
Sps_04796 | Sps_02954 | Sps_04796 | Sps_02954 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | PFAM: Methylenetetrahydrofolate reductase; 'TIGRFAM: 5,10-methylenetetrahydrofolate reductase, prokaryotic form'; Belongs to the methylenetetrahydrofolate reductase family. | 0.995 |