STRINGSTRING
fadA fadA fadB fadB Sps_00222 Sps_00222 Sps_00223 Sps_00223 Sps_00824 Sps_00824 Sps_01125 Sps_01125 Sps_01195 Sps_01195 Sps_01525 Sps_01525 fadJ fadJ fadI fadI Sps_02041 Sps_02041 Sps_02042 Sps_02042 Sps_02043 Sps_02043 Sps_02044 Sps_02044 Sps_02046 Sps_02046 Sps_02081 Sps_02081 Sps_02082 Sps_02082 Sps_02083 Sps_02083 Sps_02084 Sps_02084 Sps_02085 Sps_02085 Sps_02086 Sps_02086 Sps_02096 Sps_02096 Sps_02097 Sps_02097 Sps_03902 Sps_03902 Sps_04623 Sps_04623 Sps_05111 Sps_05111 Sps_05284 Sps_05284 Sps_05502 Sps_05502
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
fadA3-ketoacyl-CoA thiolase; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed. (387 aa)
fadBFatty oxidation complex, alpha subunit FadB; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. (717 aa)
Sps_00222'PFAM: Acyl-CoA dehydrogenase, C-terminal domain; Acyl-CoA dehydrogenase, middle domain'. (551 aa)
Sps_00223'PFAM: Acyl-CoA dehydrogenase, C-terminal domain; Acyl-CoA dehydrogenase, middle domain'. (588 aa)
Sps_00824'PFAM: Acyl-CoA dehydrogenase, C-terminal domain; Acetyl-CoA dehydrogenase C-terminal like; Acyl-CoA dehydrogenase, middle domain; Acyl-CoA dehydrogenase, N-terminal domain'. (585 aa)
Sps_01125'PFAM: Acyl-CoA dehydrogenase, C-terminal domain; Acyl-CoA dehydrogenase, middle domain; Domain of unknown function (DUF1974); Acyl-CoA dehydrogenase, N-terminal domain'. (758 aa)
Sps_01195'PFAM: Acyl-CoA dehydrogenase, C-terminal domain; Acyl-CoA dehydrogenase, middle domain; Domain of unknown function (DUF1974); Acyl-CoA dehydrogenase, N-terminal domain'. (815 aa)
Sps_01525'PFAM: Acyl-CoA dehydrogenase N terminal; Acyl-CoA dehydrogenase, C-terminal domain; Acetyl-CoA dehydrogenase C-terminal like; Acyl-CoA dehydrogenase, middle domain; Acyl-CoA dehydrogenase, N-terminal domain'. (598 aa)
fadJFatty oxidation complex, alpha subunit FadJ; Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3- hydroxyacyl-CoA dehydrogenase activities; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. (708 aa)
fadI3-ketoacyl-CoA thiolase; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed. (436 aa)
Sps_02041PFAM: NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase; NAD binding domain of 6-phosphogluconate dehydrogenase; TIGRFAM: 3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. (312 aa)
Sps_02042PFAM: Enoyl-CoA hydratase/isomerase family; 2-enoyl-CoA Hydratase C-terminal region. (377 aa)
Sps_02043PFAM: Enoyl-CoA hydratase/isomerase family; Belongs to the enoyl-CoA hydratase/isomerase family. (257 aa)
Sps_02044'PFAM: Acyl-CoA dehydrogenase, C-terminal domain; Acyl-CoA dehydrogenase, middle domain; Acyl-CoA dehydrogenase, N-terminal domain'. (385 aa)
Sps_02046acetyl-CoA acetyltransferase; 'PFAM: Thiolase, C-terminal domain; Thiolase, N-terminal domain'; TIGRFAM: acetyl-CoA acetyltransferases; Belongs to the thiolase-like superfamily. Thiolase family. (396 aa)
Sps_02081'PFAM: Acyl-CoA dehydrogenase, C-terminal domain; Acyl-CoA dehydrogenase, middle domain; Acyl-CoA dehydrogenase, N-terminal domain'. (389 aa)
Sps_02082acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta); PFAM: Carboxyl transferase domain. (535 aa)
Sps_02083PFAM: Enoyl-CoA hydratase/isomerase family. (291 aa)
Sps_020843-methylcrotonoyl-CoA carboxylase, alpha subunit; 'PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domain; Biotin carboxylase C-terminal domain; Carbamoyl-phosphate synthase L chain, N-terminal domain; Biotin-requiring enzyme'; 'TIGRFAM: acetyl-CoA carboxylase, biotin carboxylase subunit'. (701 aa)
Sps_02085Hypothetical protein. (53 aa)
Sps_02086hydroxymethylglutaryl-CoA lyase; PFAM: HMGL-like. (296 aa)
Sps_02096PFAM: Electron transfer flavoprotein domain; Electron transfer flavoprotein FAD-binding domain. (307 aa)
Sps_02097PFAM: Electron transfer flavoprotein domain. (249 aa)
Sps_03902'PFAM: Acyl-CoA dehydrogenase, C-terminal domain; Domain of unknown function (DUF1974); Acyl-CoA dehydrogenase, N-terminal domain'. (745 aa)
Sps_04623'PFAM: Acyl-CoA dehydrogenase, C-terminal domain; Acyl-CoA dehydrogenase, middle domain; Acyl-CoA dehydrogenase, N-terminal domain'. (391 aa)
Sps_05111PFAM: Enoyl-CoA hydratase/isomerase family. (245 aa)
Sps_05284enoyl-CoA hydratase/carnithine racemase; PFAM: Enoyl-CoA hydratase/isomerase family; Belongs to the enoyl-CoA hydratase/isomerase family. (268 aa)
Sps_05502Flavin-dependent dehydrogenase; Accepts electrons from ETF and reduces ubiquinone. (549 aa)
Your Current Organism:
Shewanella psychrophila
NCBI taxonomy Id: 225848
Other names: CGMCC 1.6159, JCM 13876, S. psychrophila, Shewanella psychrophila Xiao et al. 2007 emend. Thorell et al. 2019, Shewanella sp. WP2, strain WP2
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