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ubiG ubiG Sps_00060 Sps_00060 Sps_00062 Sps_00062 hemF hemF Sps_00130 Sps_00130 Sps_00268 Sps_00268 ubiG-2 ubiG-2 Sps_01385 Sps_01385 Sps_01534 Sps_01534 Sps_01595 Sps_01595 hemH hemH Sps_02433 Sps_02433 Sps_02460 Sps_02460 hemL hemL Sps_02632 Sps_02632 Sps_02782 Sps_02782 Sps_02789 Sps_02789 Sps_02810 Sps_02810 ubiE ubiE Sps_03050 Sps_03050 ubiB ubiB tatA tatA tatB tatB tatC tatC Sps_03055 Sps_03055 Sps_03056 Sps_03056 Sps_03057 Sps_03057 Sps_03058 Sps_03058 hemC hemC Sps_03090 Sps_03090 Sps_03091 Sps_03091 Sps_03092 Sps_03092 ubiA ubiA hemE hemE ubiD ubiD Sps_03603 Sps_03603 Sps_03856 Sps_03856 Sps_03857 Sps_03857 Sps_04238 Sps_04238 hemA hemA Sps_04360 Sps_04360 Sps_04565 Sps_04565 Sps_04783 Sps_04783 cobQ cobQ Sps_04785 Sps_04785 cobS cobS cobT cobT Sps_04790 Sps_04790 Sps_04851 Sps_04851 Sps_04852 Sps_04852 ubiX ubiX Sps_05072 Sps_05072 Sps_05073 Sps_05073 orn orn
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ubiG3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. (257 aa)
Sps_00060PFAM: Flavodoxin domain. (175 aa)
Sps_00062PFAM: Flavodoxin domain. (179 aa)
hemFCoproporphyrinogen oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. (307 aa)
Sps_00130Oxygen-independent coproporphyrinogen III oxidase; PFAM: HemN C-terminal domain; Radical SAM superfamily; TIGRFAM: oxygen-independent coproporphyrinogen III oxidase; Belongs to the anaerobic coproporphyrinogen-III oxidase family. (458 aa)
Sps_00268cob(II)yrinic acid a,c-diamide reductase; PFAM: Nitroreductase family; 'TIGRFAM: 5,6-dimethylbenzimidazole synthase'. (219 aa)
ubiG-23-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. (241 aa)
Sps_01385Hydrolase, TatD family; PFAM: TatD related DNase; 'TIGRFAM: hydrolase, TatD family'. (262 aa)
Sps_01534PFAM: Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (234 aa)
Sps_01595uroporphyrinogen-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: uroporphyrin-III C-methyltransferase. (288 aa)
hemHFerrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (331 aa)
Sps_02433DNA replication and repair protein RecO; Involved in DNA repair and RecF pathway recombination. (225 aa)
Sps_02460PFAM: CobD/Cbib protein. (327 aa)
hemLPFAM: Aminotransferase class-III; 'TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase'. (428 aa)
Sps_02632Radical SAM protein, TatD family-associated; PFAM: Radical SAM superfamily; 4Fe-4S single cluster domain; 'TIGRFAM: radical SAM protein, TatD family-associated'. (205 aa)
Sps_02782PFAM: Flavodoxin domain. (173 aa)
Sps_02789uroporphyrinogen-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. (292 aa)
Sps_02810PFAM: AFG1-like ATPase. (379 aa)
ubiEUbiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). (251 aa)
Sps_03050Hypothetical protein; PFAM: SCP-2 sterol transfer family. (205 aa)
ubiB2-octaprenylphenol hydroxylase; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis. (549 aa)
tatATwin arginine-targeting protein translocase, TatA/E family; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. (79 aa)
tatBTwin arginine-targeting protein translocase TatB; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation. (135 aa)
tatCSec-independent protein translocase TatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides. (256 aa)
Sps_03055Hypothetical protein. (178 aa)
Sps_03056Sec-independent protein translocase TatD; PFAM: TatD related DNase; 'TIGRFAM: hydrolase, TatD family'. (279 aa)
Sps_03057Diguanylate cyclase (GGDEF) domain-containing protein; PFAM: 7TM diverse intracellular signalling; GGDEF domain; 7TMR-DISM extracellular 2; TIGRFAM: diguanylate cyclase (GGDEF) domain. (621 aa)
Sps_03058PFAM: Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (338 aa)
hemCHydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (309 aa)
Sps_03090uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (216 aa)
Sps_03091Putative enzyme of heme biosynthesis; PFAM: HemX. (380 aa)
Sps_03092PFAM: HemY protein N-terminus; TIGRFAM: heme biosynthesis-associated TPR protein. (389 aa)
ubiA4-hydroxybenzoate polyprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. (288 aa)
hemEUroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (354 aa)
ubiD3-octaprenyl-4hydroxybenzoate decarboxylase; Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis. (489 aa)
Sps_03603Siroheme synthase, N-terminal domain; PFAM: Sirohaem biosynthesis protein central; Putative NAD(P)-binding; Sirohaem synthase dimerisation region; 'TIGRFAM: siroheme synthase, N-terminal domain'. (303 aa)
Sps_03856Hypothetical protein; PFAM: RnfH family Ubiquitin; Belongs to the UPF0125 (RnfH) family. (110 aa)
Sps_03857Oligoketide cyclase/lipid transport protein; PFAM: Polyketide cyclase / dehydrase and lipid transport. (143 aa)
Sps_04238PFAM: TatD related DNase; 'TIGRFAM: hydrolase, TatD family'. (261 aa)
hemAglutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (426 aa)
Sps_04360PFAM: FAD binding domain; 'TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family'. (397 aa)
Sps_04565PFAM: Aminotransferase class-III; 'TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase'; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (448 aa)
Sps_04783cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. (217 aa)
cobQAdenosylcobyric acid synthase (glutamine-hydrolysing); Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (539 aa)
Sps_04785Adenosylcobinamide-phosphate guanylyltransferase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. (184 aa)
cobSCobalamin-5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. (257 aa)
cobTNicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). (342 aa)
Sps_04790Fructose-2,6-bisphosphatase; PFAM: Histidine phosphatase superfamily (branch 1). (170 aa)
Sps_04851PFAM: FAD binding domain; 'TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family'. (408 aa)
Sps_04852PFAM: FAD binding domain; 'TIGRFAM: 2-polyprenyl-6-methoxyphenol 4-hydroxylase; Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family'. (428 aa)
ubiXPolyprenyl p-hydroxybenzoate/phenylacrylic acid decarboxylase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. (220 aa)
Sps_05072PFAM: Stringent starvation protein B. (172 aa)
Sps_05073'PFAM: Glutathione S-transferase, N-terminal domain; Glutathione S-transferase, C-terminal domain'; Belongs to the GST superfamily. (209 aa)
ornOligoribonuclease (3'->5' exoribonuclease); 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family. (181 aa)
Your Current Organism:
Shewanella psychrophila
NCBI taxonomy Id: 225848
Other names: CGMCC 1.6159, JCM 13876, S. psychrophila, Shewanella psychrophila Xiao et al. 2007 emend. Thorell et al. 2019, Shewanella sp. WP2, strain WP2
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