STRINGSTRING
Sps_00060 Sps_00060 Sps_00062 Sps_00062 hemF hemF Sps_00130 Sps_00130 Sps_01534 Sps_01534 Sps_01595 Sps_01595 hemH hemH hemL hemL Sps_02782 Sps_02782 Sps_02789 Sps_02789 Sps_03058 Sps_03058 hemC hemC Sps_03090 Sps_03090 Sps_03091 Sps_03091 Sps_03092 Sps_03092 hemE hemE Sps_03603 Sps_03603 hemA hemA Sps_04565 Sps_04565
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Sps_00060PFAM: Flavodoxin domain. (175 aa)
Sps_00062PFAM: Flavodoxin domain. (179 aa)
hemFCoproporphyrinogen oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. (307 aa)
Sps_00130Oxygen-independent coproporphyrinogen III oxidase; PFAM: HemN C-terminal domain; Radical SAM superfamily; TIGRFAM: oxygen-independent coproporphyrinogen III oxidase; Belongs to the anaerobic coproporphyrinogen-III oxidase family. (458 aa)
Sps_01534PFAM: Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (234 aa)
Sps_01595uroporphyrinogen-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: uroporphyrin-III C-methyltransferase. (288 aa)
hemHFerrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (331 aa)
hemLPFAM: Aminotransferase class-III; 'TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase'. (428 aa)
Sps_02782PFAM: Flavodoxin domain. (173 aa)
Sps_02789uroporphyrinogen-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. (292 aa)
Sps_03058PFAM: Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (338 aa)
hemCHydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (309 aa)
Sps_03090uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (216 aa)
Sps_03091Putative enzyme of heme biosynthesis; PFAM: HemX. (380 aa)
Sps_03092PFAM: HemY protein N-terminus; TIGRFAM: heme biosynthesis-associated TPR protein. (389 aa)
hemEUroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (354 aa)
Sps_03603Siroheme synthase, N-terminal domain; PFAM: Sirohaem biosynthesis protein central; Putative NAD(P)-binding; Sirohaem synthase dimerisation region; 'TIGRFAM: siroheme synthase, N-terminal domain'. (303 aa)
hemAglutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (426 aa)
Sps_04565PFAM: Aminotransferase class-III; 'TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase'; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (448 aa)
Your Current Organism:
Shewanella psychrophila
NCBI taxonomy Id: 225848
Other names: CGMCC 1.6159, JCM 13876, S. psychrophila, Shewanella psychrophila Xiao et al. 2007 emend. Thorell et al. 2019, Shewanella sp. WP2, strain WP2
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