STRINGSTRING
hisH hisH glmS glmS Sps_05252 Sps_05252 cobQ cobQ Sps_04476 Sps_04476 carA carA pyrG pyrG guaA guaA purL purL Sps_03358 Sps_03358 Sps_02949 Sps_02949 Sps_02561 Sps_02561 Sps_02560 Sps_02560 Sps_02457 Sps_02457 glsA glsA purF purF Sps_01298 Sps_01298 Sps_01295 Sps_01295 Sps_01194 Sps_01194 Sps_00480 Sps_00480
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
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gene fusions
gene co-occurrence
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textmining
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Your Input:
hisHImidazole glycerol phosphate synthase subunit hisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (231 aa)
glmSGlutamine--fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (609 aa)
Sps_05252GMP synthase family protein; PFAM: Glutamine amidotransferase class-I. (238 aa)
cobQAdenosylcobyric acid synthase (glutamine-hydrolysing); Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (539 aa)
Sps_04476Glutamate synthase family protein; PFAM: Iron-binding zinc finger CDGSH type; Conserved region in glutamate synthase; Belongs to the glutamate synthase family. (523 aa)
carA'PFAM: Carbamoyl-phosphate synthase small chain, CPSase domain; Glutamine amidotransferase class-I'; 'TIGRFAM: carbamoyl-phosphate synthase, small subunit'; Belongs to the CarA family. (381 aa)
pyrGCTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (545 aa)
guaAGMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. (525 aa)
purLPhosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. (1293 aa)
Sps_03358'PFAM: Glutamine synthetase, catalytic domain; Glutamine synthetase, beta-Grasp domain'; 'TIGRFAM: glutamine synthetase, type I'. (469 aa)
Sps_02949PFAM: Cysteine-rich CWC. (75 aa)
Sps_02561Gamma-glutamyl-gamma-aminobutyrate hydrolase; PFAM: Peptidase C26. (253 aa)
Sps_02560'PFAM: Glutamine synthetase, catalytic domain'. (449 aa)
Sps_02457Glutamate synthase (NADPH) large subunit; PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II. (1482 aa)
glsAL-glutaminase; PFAM: Glutaminase; TIGRFAM: glutaminase A; Belongs to the glutaminase family. (304 aa)
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (504 aa)
Sps_01298'PFAM: Glutamine synthetase, catalytic domain'. (459 aa)
Sps_01295GMP synthase family protein; PFAM: Glutamine amidotransferase class-I. (232 aa)
Sps_01194PFAM: Glutamine amidotransferases class-II. (263 aa)
Sps_00480Asparagine synthase, glutamine-hydrolyzing; PFAM: Glutamine amidotransferase domain; Asparagine synthase; TIGRFAM: asparagine synthase (glutamine-hydrolyzing). (558 aa)
Your Current Organism:
Shewanella psychrophila
NCBI taxonomy Id: 225848
Other names: CGMCC 1.6159, JCM 13876, S. psychrophila, Shewanella psychrophila Xiao et al. 2007 emend. Thorell et al. 2019, Shewanella sp. WP2, strain WP2
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