STRINGSTRING
Sps_04488 Sps_04488 Sps_00050 Sps_00050 Sps_00462 Sps_00462 Sps_00480 Sps_00480 Sps_00596 Sps_00596 astE astE Sps_01099 Sps_01099 Sps_01194 Sps_01194 Sps_01295 Sps_01295 Sps_01298 Sps_01298 hisH hisH speA speA Sps_01623 Sps_01623 Sps_01634 Sps_01634 astB astB purF purF Sps_02099 Sps_02099 Sps_02100 Sps_02100 proC proC glsA glsA Sps_02457 Sps_02457 Sps_02560 Sps_02560 Sps_02561 Sps_02561 argR argR Sps_02949 Sps_02949 Sps_03048 Sps_03048 argA argA Sps_03336 Sps_03336 Sps_03358 Sps_03358 purL purL guaA guaA pyrG pyrG carB carB carA carA Sps_04277 Sps_04277 proA proA proB proB Sps_04476 Sps_04476 Sps_04487 Sps_04487 cobQ cobQ Sps_04806 Sps_04806 Sps_05022 Sps_05022 astD astD Sps_05067 Sps_05067 argD argD Sps_05252 Sps_05252 argH argH argG argG Sps_05420 Sps_05420 argB argB argC argC Sps_05423 Sps_05423 Sps_05517 Sps_05517 hutH hutH hutU hutU hutI hutI glmS glmS
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Sps_04488Hypothetical protein; PFAM: Amidohydrolase. (114 aa)
Sps_00050Amidohydrolase, imidazolonepropionase; PFAM: Amidohydrolase; WD40-like Beta Propeller Repeat; Amidohydrolase family. (1081 aa)
Sps_00462Acetyltransferase, GNAT family; PFAM: Acetyltransferase (GNAT) domain. (155 aa)
Sps_00480Asparagine synthase, glutamine-hydrolyzing; PFAM: Glutamine amidotransferase domain; Asparagine synthase; TIGRFAM: asparagine synthase (glutamine-hydrolyzing). (558 aa)
Sps_00596PFAM: Bacterial NAD-glutamate dehydrogenase. (1612 aa)
astESuccinylglutamate desuccinylase; Transforms N(2)-succinylglutamate into succinate and glutamate; Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily. (344 aa)
Sps_01099PFAM: Ornithine cyclodeaminase/mu-crystallin family. (332 aa)
Sps_01194PFAM: Glutamine amidotransferases class-II. (263 aa)
Sps_01295GMP synthase family protein; PFAM: Glutamine amidotransferase class-I. (232 aa)
Sps_01298'PFAM: Glutamine synthetase, catalytic domain'. (459 aa)
hisHImidazole glycerol phosphate synthase subunit hisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (231 aa)
speAArginine decarboxylase; Catalyzes the biosynthesis of agmatine from arginine. (637 aa)
Sps_01623PFAM: Conserved region in glutamate synthase; Belongs to the glutamate synthase family. (547 aa)
Sps_01634Acetyltransferase, GNAT family; PFAM: Acetyltransferase (GNAT) domain. (158 aa)
astBSuccinylarginine dihydrolase; Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)- succinylornithine, ammonia and CO(2). (445 aa)
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (504 aa)
Sps_02099Amidohydrolase, imidazolonepropionase; PFAM: Amidohydrolase; Amidohydrolase family. (1027 aa)
Sps_02100Amidohydrolase, imidazolonepropionase; PFAM: Amidohydrolase. (454 aa)
proCPyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (272 aa)
glsAL-glutaminase; PFAM: Glutaminase; TIGRFAM: glutaminase A; Belongs to the glutaminase family. (304 aa)
Sps_02457Glutamate synthase (NADPH) large subunit; PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II. (1482 aa)
Sps_02560'PFAM: Glutamine synthetase, catalytic domain'. (449 aa)
Sps_02561Gamma-glutamyl-gamma-aminobutyrate hydrolase; PFAM: Peptidase C26. (253 aa)
argRTranscriptional regulator, ArgR family; Regulates arginine biosynthesis genes. (156 aa)
Sps_02949PFAM: Cysteine-rich CWC. (75 aa)
Sps_03048Arginase family hydrolase, arginase/agmainase/formiminoglutamate hydrolase; PFAM: Arginase family; Belongs to the arginase family. (347 aa)
argAN-acetylglutamate synthase; PFAM: Acetyltransferase (GNAT) family; Amino acid kinase family; TIGRFAM: amino-acid N-acetyltransferase; Belongs to the acetyltransferase family. ArgA subfamily. (439 aa)
Sps_03336Histidine ammonia-lyase; PFAM: Aromatic amino acid lyase; TIGRFAM: phenylalanine ammonia-lyase. (520 aa)
Sps_03358'PFAM: Glutamine synthetase, catalytic domain; Glutamine synthetase, beta-Grasp domain'; 'TIGRFAM: glutamine synthetase, type I'. (469 aa)
purLPhosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. (1293 aa)
guaAGMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. (525 aa)
pyrGCTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (545 aa)
carB'PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domain; MGS-like domain; Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Carbamoyl-phosphate synthase L chain, N-terminal domain'; 'TIGRFAM: carbamoyl-phosphate synthase, large subunit'; Belongs to the CarB family. (1072 aa)
carA'PFAM: Carbamoyl-phosphate synthase small chain, CPSase domain; Glutamine amidotransferase class-I'; 'TIGRFAM: carbamoyl-phosphate synthase, small subunit'; Belongs to the CarA family. (381 aa)
Sps_04277PFAM: Acetyltransferase (GNAT) family. (142 aa)
proAGlutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (424 aa)
proBGlutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (374 aa)
Sps_04476Glutamate synthase family protein; PFAM: Iron-binding zinc finger CDGSH type; Conserved region in glutamate synthase; Belongs to the glutamate synthase family. (523 aa)
Sps_04487Hypothetical protein; PFAM: Amidohydrolase family. (70 aa)
cobQAdenosylcobyric acid synthase (glutamine-hydrolysing); Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (539 aa)
Sps_048062,3-diaminopropionate biosynthesis protein SbnB; PFAM: Ornithine cyclodeaminase/mu-crystallin family; 'TIGRFAM: 2,3-diaminopropionate biosynthesis protein SbnB'. (337 aa)
Sps_05022Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. (1059 aa)
astDSuccinylglutamic semialdehyde dehydrogenase; Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate. (486 aa)
Sps_05067PFAM: Arginine N-succinyltransferase beta subunit; TIGRFAM: arginine N-succinyltransferase; arginine and ornithine succinyltransferase subunits. (339 aa)
argDAcetylornithine aminotransferase apoenzyme; PFAM: Aminotransferase class-III; 'TIGRFAM: succinylornithine transaminase family; transaminase, acetylornithine/succinylornithine family'; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (405 aa)
Sps_05252GMP synthase family protein; PFAM: Glutamine amidotransferase class-I. (238 aa)
argHPFAM: Lyase; Argininosuccinate lyase C-terminal; TIGRFAM: argininosuccinate lyase. (455 aa)
argGPFAM: Arginosuccinate synthase; TIGRFAM: argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (407 aa)
Sps_05420Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (302 aa)
argBN-acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (261 aa)
argCN-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (326 aa)
Sps_05423Acetylornithine deacetylase; PFAM: Peptidase family M20/M25/M40; Peptidase dimerisation domain; TIGRFAM: acetylornithine deacetylase (ArgE). (383 aa)
Sps_05517PFAM: Acetyltransferase (GNAT) family. (159 aa)
hutHHistidine ammonia-lyase; PFAM: Aromatic amino acid lyase; TIGRFAM: histidine ammonia-lyase. (510 aa)
hutUUrocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate. (556 aa)
hutIImidazolonepropionase; PFAM: Amidohydrolase; TIGRFAM: imidazolonepropionase. (408 aa)
glmSGlutamine--fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (609 aa)
Your Current Organism:
Shewanella psychrophila
NCBI taxonomy Id: 225848
Other names: CGMCC 1.6159, JCM 13876, S. psychrophila, Shewanella psychrophila Xiao et al. 2007 emend. Thorell et al. 2019, Shewanella sp. WP2, strain WP2
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