STRINGSTRING
Sps_03575 Sps_03575 ubiG ubiG Sps_00215 Sps_00215 Sps_00297 Sps_00297 Sps_00298 Sps_00298 menD menD ubiG-2 ubiG-2 Sps_00947 Sps_00947 Sps_01156 Sps_01156 gloB gloB Sps_01639 Sps_01639 kynA kynA menA menA Sps_02632 Sps_02632 ubiE ubiE Sps_03050 Sps_03050 ubiB ubiB Sps_03113 Sps_03113 ubiA ubiA ubiD ubiD Sps_03366 Sps_03366 Sps_03393 Sps_03393 Sps_03857 Sps_03857 Sps_04192 Sps_04192 Sps_04194 Sps_04194 Sps_04278 Sps_04278 Sps_04360 Sps_04360 Sps_04851 Sps_04851 Sps_04852 Sps_04852 Sps_05464 Sps_05464 ubiC ubiC menB menB
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
Sps_03575PFAM: Polyketide cyclase / dehydrase and lipid transport. (217 aa)
ubiG3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. (257 aa)
Sps_002152-polyprenyl-6-methoxyphenol hydroxylase-like oxidoreductase; PFAM: FAD binding domain. (405 aa)
Sps_00297O-succinylbenzoate synthase; 'PFAM: Mandelate racemase / muconate lactonizing enzyme, C-terminal domain'; TIGRFAM: o-succinylbenzoate synthase. (355 aa)
Sps_002982-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Catalyzes a proton abstraction reaction that results in 2,5- elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6- hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). (260 aa)
menD2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily. (569 aa)
ubiG-23-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. (241 aa)
Sps_00947PFAM: Glyoxalase-like domain; TIGRFAM: lactoylglutathione lyase. (134 aa)
Sps_01156Lactoylglutathione lyase; PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; TIGRFAM: lactoylglutathione lyase. (136 aa)
gloBHydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid. (269 aa)
Sps_01639Zn-dependent hydrolase, glyoxylase; PFAM: Metallo-beta-lactamase superfamily. (289 aa)
kynATryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. (281 aa)
menA1,4-dihydroxy-2-naphthoate prenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. (290 aa)
Sps_02632Radical SAM protein, TatD family-associated; PFAM: Radical SAM superfamily; 4Fe-4S single cluster domain; 'TIGRFAM: radical SAM protein, TatD family-associated'. (205 aa)
ubiEUbiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). (251 aa)
Sps_03050Hypothetical protein; PFAM: SCP-2 sterol transfer family. (205 aa)
ubiB2-octaprenylphenol hydroxylase; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis. (549 aa)
Sps_03113Hypothetical protein; PFAM: Membrane fusogenic activity. (86 aa)
ubiA4-hydroxybenzoate polyprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. (288 aa)
ubiD3-octaprenyl-4hydroxybenzoate decarboxylase; Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis. (489 aa)
Sps_03366PFAM: Chorismate lyase. (163 aa)
Sps_03393PFAM: Methyltransferase domain. (194 aa)
Sps_03857Oligoketide cyclase/lipid transport protein; PFAM: Polyketide cyclase / dehydrase and lipid transport. (143 aa)
Sps_04192Putative lipid carrier protein; PFAM: SCP-2 sterol transfer family. (170 aa)
Sps_04194Collagenase-like protease; PFAM: Peptidase family U32. (289 aa)
Sps_04278Zn-dependent hydrolase, glyoxylase; PFAM: Metallo-beta-lactamase superfamily. (278 aa)
Sps_04360PFAM: FAD binding domain; 'TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family'. (397 aa)
Sps_04851PFAM: FAD binding domain; 'TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family'. (408 aa)
Sps_04852PFAM: FAD binding domain; 'TIGRFAM: 2-polyprenyl-6-methoxyphenol 4-hydroxylase; Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family'. (428 aa)
Sps_05464PFAM: Methyltransferase domain. (264 aa)
ubiCChorismate lyase; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway; Belongs to the UbiC family. (187 aa)
menB1,4-Dihydroxy-2-naphthoyl-CoA synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA); Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily. (301 aa)
Your Current Organism:
Shewanella psychrophila
NCBI taxonomy Id: 225848
Other names: CGMCC 1.6159, JCM 13876, S. psychrophila, Shewanella psychrophila Xiao et al. 2007 emend. Thorell et al. 2019, Shewanella sp. WP2, strain WP2
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