STRINGSTRING
Sps_04549 Sps_04549 Sps_03514 Sps_03514 Sps_03037 Sps_03037 Sps_03318 Sps_03318 Sps_00045 Sps_00045 Sps_00177 Sps_00177 Sps_00417 Sps_00417 Sps_00776 Sps_00776 Sps_00775 Sps_00775 Sps_00927 Sps_00927 Sps_01308 Sps_01308 glnD glnD cca cca Sps_02665 Sps_02665 glnD-2 glnD-2 Sps_02840 Sps_02840
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Sps_04549PFAM: HD domain; GAF domain. (538 aa)
Sps_03514Metal dependent phosphohydrolase; PFAM: Domain of unknown function (DUF3391); HD domain; TIGRFAM: HDIG domain. (410 aa)
Sps_03037HD-GYP domain-containing protein; 'PFAM: HD domain; HAMP domain; Bacterial extracellular solute-binding proteins, family 3'. (1065 aa)
Sps_03318(p)ppGpp synthetase, RelA/SpoT family; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (701 aa)
Sps_00045Putative signal transduction protein; PFAM: HDOD domain. (355 aa)
Sps_00177Metal dependent phosphohydrolase; PFAM: Domain of unknown function (DUF3391); HD domain. (392 aa)
Sps_00417Metal dependent phosphohydrolase; PFAM: Domain of unknown function (DUF3391); HD domain; TIGRFAM: HDIG domain. (431 aa)
Sps_00776Putative HD superfamily hydrolase; Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates. (195 aa)
Sps_00775Hypothetical protein; PFAM: HD domain; 'TIGRFAM: deoxyguanosinetriphosphate triphosphohydrolase, putative'. (197 aa)
Sps_00927PFAM: HD domain; Domain of unknown function (DUF3369); Response regulator receiver domain. (531 aa)
Sps_01308Uncharacterized domain HDIG-containing protein; PFAM: Domain of unknown function (DUF3391); HD domain; TIGRFAM: HDIG domain. (410 aa)
glnDUTP--GlnB (protein PII) uridylyltransferase, GlnD; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism. (857 aa)
ccaMetal dependent phosphohydrolase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases. (413 aa)
Sps_02665Putative HD superfamily hydrolase; PFAM: HD domain. (199 aa)
glnD-2UTP--GlnB (protein PII) uridylyltransferase, GlnD; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism. (867 aa)
Sps_02840Putative HD superfamily hydrolase; PFAM: HD domain. (208 aa)
Your Current Organism:
Shewanella psychrophila
NCBI taxonomy Id: 225848
Other names: CGMCC 1.6159, JCM 13876, S. psychrophila, Shewanella psychrophila Xiao et al. 2007 emend. Thorell et al. 2019, Shewanella sp. WP2, strain WP2
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