STRINGSTRING
Sps_04293 Sps_04293 Sps_05472 Sps_05472 Sps_05378 Sps_05378 Sps_04930 Sps_04930 Sps_04895 Sps_04895 Sps_04469 Sps_04469 Sps_04294 Sps_04294 Sps_04287 Sps_04287 secD-2 secD-2 secF-2 secF-2 Sps_04252 Sps_04252 Sps_04206 Sps_04206 Sps_04081 Sps_04081 Sps_04034 Sps_04034 Sps_03638 Sps_03638 secD secD secF secF Sps_03504 Sps_03504 secA secA Sps_03193 Sps_03193 Sps_03069 Sps_03069 Sps_02869 Sps_02869 Sps_02860 Sps_02860 Sps_02793 Sps_02793 Sps_02273 Sps_02273 Sps_02200 Sps_02200 Sps_02065 Sps_02065 tpx tpx Sps_01934 Sps_01934 Sps_01871 Sps_01871 Sps_01772 Sps_01772 Sps_01771 Sps_01771 Sps_01667 Sps_01667 msbA msbA Sps_01627 Sps_01627 Sps_01075 Sps_01075 Sps_00897 Sps_00897 Sps_00896 Sps_00896 Sps_00791 Sps_00791 msrA msrA Sps_00635 Sps_00635 Sps_00622 Sps_00622 Sps_00502 Sps_00502 secY secY secE secE Sps_00216 Sps_00216
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Sps_04293Bacterioferritin; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family. (155 aa)
Sps_05472Ferritin-like protein; Iron-storage protein. (175 aa)
Sps_05378Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase, long form; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (625 aa)
Sps_04930Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. (189 aa)
Sps_04895PFAM: ABC transporter; ABC transporter transmembrane region; 'TIGRFAM: ABC transporter, permease/ATP-binding protein'. (634 aa)
Sps_04469Thiol-disulfide isomerase-like thioredoxin; PFAM: AhpC/TSA family. (186 aa)
Sps_04294Bacterioferritin; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family. (156 aa)
Sps_04287PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; TIGRFAM: S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (386 aa)
secD-2Protein-export membrane protein, SecD/SecF family; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. (604 aa)
secF-2Protein-export membrane protein, SecD/SecF family; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. (315 aa)
Sps_04252Protein translocase subunit secG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. (114 aa)
Sps_04206Hypothetical protein. (164 aa)
Sps_04081Truncated hemoglobin; PFAM: Bacterial-like globin. (120 aa)
Sps_04034Truncated hemoglobin; PFAM: Bacterial-like globin. (117 aa)
Sps_03638ABC-type multidrug transport system, ATPase and permease component; PFAM: ABC transporter; ABC transporter transmembrane region. (609 aa)
secDProtein-export membrane protein, SecD/SecF family; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. (605 aa)
secFProtein translocase subunit secF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. (315 aa)
Sps_03504Thiol peroxidase (atypical 2-Cys peroxiredoxin); Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. (169 aa)
secAProtein translocase subunit secA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family. (907 aa)
Sps_03193PFAM: Redoxin. (165 aa)
Sps_03069PFAM: Thioredoxin; TIGRFAM: thioredoxin; Belongs to the thioredoxin family. (108 aa)
Sps_02869'PFAM: Bacterial extracellular solute-binding proteins, family 5 Middle'. (564 aa)
Sps_02860Truncated hemoglobin; PFAM: Bacterial-like globin. (137 aa)
Sps_02793Peroxiredoxin; PFAM: AhpC/TSA family. (174 aa)
Sps_02273PFAM: AhpC/TSA family. (157 aa)
Sps_02200Alkylhydroperoxidase AhpD family core domain; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family. (145 aa)
Sps_02065Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. (202 aa)
tpxThiol peroxidase (atypical 2-Cys peroxiredoxin); Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Tpx subfamily. (165 aa)
Sps_01934Putative peroxidase-related enzyme; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family. (181 aa)
Sps_01871ABC-type dipeptide transport system, periplasmic component; 'PFAM: Bacterial extracellular solute-binding proteins, family 5 Middle'. (545 aa)
Sps_01772ABC-type multidrug transport system, ATPase and permease component; PFAM: ABC transporter; ABC transporter transmembrane region. (550 aa)
Sps_01771ABC-type multidrug transport system, ATPase and permease component; PFAM: ABC transporter; ABC transporter transmembrane region. (562 aa)
Sps_01667Thioredoxin domain-containing protein; PFAM: Thioredoxin; Tetratricopeptide repeat. (281 aa)
msbALipid A export permease/ATP-binding protein MsbA; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. (606 aa)
Sps_016272-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (396 aa)
Sps_01075PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: thioredoxin-disulfide reductase. (317 aa)
Sps_00897Bacterioferritin; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family. (156 aa)
Sps_00896Bacterioferritin; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family. (160 aa)
Sps_00791Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase component; PFAM: 2-oxoacid dehydrogenases acyltransferase (catalytic domain); e3 binding domain; Biotin-requiring enzyme. (536 aa)
msrAmethionine-S-sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. (159 aa)
Sps_00635Peroxiredoxin; PFAM: AhpC/TSA family. (154 aa)
Sps_00622Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (193 aa)
Sps_00502Peroxiredoxin; PFAM: C-terminal domain of 1-Cys peroxiredoxin; AhpC/TSA family. (201 aa)
secYProtein translocase subunit secY/sec61 alpha; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. (446 aa)
secEProtein translocase subunit secE/sec61 gamma; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation; Belongs to the SecE/SEC61-gamma family. (123 aa)
Sps_00216PFAM: 2-oxoacid dehydrogenases acyltransferase (catalytic domain). (255 aa)
Your Current Organism:
Shewanella psychrophila
NCBI taxonomy Id: 225848
Other names: CGMCC 1.6159, JCM 13876, S. psychrophila, Shewanella psychrophila Xiao et al. 2007 emend. Thorell et al. 2019, Shewanella sp. WP2, strain WP2
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