STRINGSTRING
Sps_01835 Sps_01835 Sps_01406 Sps_01406 Sps_00911 Sps_00911 Sps_00814 Sps_00814 Sps_00778 Sps_00778 glyA-2 glyA-2 glyA glyA Sps_00649 Sps_00649 Sps_00575 Sps_00575 argD argD glyA-3 glyA-3 Sps_03196 Sps_03196 Sps_02956 Sps_02956 Sps_02671 Sps_02671 Sps_01864 Sps_01864
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Sps_01835Valine-pyruvate aminotransferase apoenzyme; PFAM: Aminotransferase class I and II. (416 aa)
Sps_01406Transcriptional regulator, GntR family; 'PFAM: Aminotransferase class I and II; Bacterial regulatory proteins, gntR family'. (456 aa)
Sps_00911PFAM: Aminotransferase class I and II. (397 aa)
Sps_00814PFAM: Aminotransferase class I and II. (401 aa)
Sps_00778PFAM: Aminotransferase class I and II. (404 aa)
glyA-2Glycine/serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (421 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (431 aa)
Sps_00649Putative PLP-dependent enzyme; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase family; Belongs to the DegT/DnrJ/EryC1 family. (394 aa)
Sps_00575Cystathionine beta-lyase; PFAM: Cys/Met metabolism PLP-dependent enzyme; 'TIGRFAM: cystathionine beta-lyase, bacterial'. (392 aa)
argDAcetylornithine aminotransferase apoenzyme; PFAM: Aminotransferase class-III; 'TIGRFAM: succinylornithine transaminase family; transaminase, acetylornithine/succinylornithine family'; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (405 aa)
glyA-3Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (418 aa)
Sps_03196Transcriptional regulator, GntR family; 'PFAM: Aminotransferase class I and II; Bacterial regulatory proteins, gntR family'. (478 aa)
Sps_02956Cystathionine gamma-synthase; PFAM: Cys/Met metabolism PLP-dependent enzyme; TIGRFAM: O-succinylhomoserine (thiol)-lyase. (386 aa)
Sps_02671Aspartate 4-decarboxylase; PFAM: Aminotransferase class I and II; TIGRFAM: aspartate 4-decarboxylase. (529 aa)
Sps_01864Cystathionine beta-lyase/cystathionine gamma-synthase; PFAM: Cys/Met metabolism PLP-dependent enzyme; TIGRFAM: methionine gamma-lyase. (392 aa)
Your Current Organism:
Shewanella psychrophila
NCBI taxonomy Id: 225848
Other names: CGMCC 1.6159, JCM 13876, S. psychrophila, Shewanella psychrophila Xiao et al. 2007 emend. Thorell et al. 2019, Shewanella sp. WP2, strain WP2
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