STRINGSTRING
murB murB Sps_00530 Sps_00530 Sps_00657 Sps_00657 Sps_00717 Sps_00717 Sps_00786 Sps_00786 Sps_00810 Sps_00810 Sps_01355 Sps_01355 nagZ nagZ Sps_01966 Sps_01966 Sps_02142 Sps_02142 glgC glgC Sps_02362 Sps_02362 Sps_02363 Sps_02363 Sps_02364 Sps_02364 pgi pgi Sps_02581 Sps_02581 galK galK Sps_03256 Sps_03256 Sps_03257 Sps_03257 Sps_03667 Sps_03667 Sps_03668 Sps_03668 Sps_03673 Sps_03673 Sps_03694 Sps_03694 Sps_03721 Sps_03721 Sps_03723 Sps_03723 Sps_03724 Sps_03724 Sps_03727 Sps_03727 Sps_04137 Sps_04137 glmM glmM Sps_04639 Sps_04639 Sps_04640 Sps_04640 nagB nagB murA murA glmS glmS glmU glmU
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
murBUDP-N-acetylmuramate dehydrogenase; Cell wall formation. (343 aa)
Sps_00530Chitinase; PFAM: Glycosyl hydrolases family 18; Carbohydrate binding domain. (892 aa)
Sps_00657PTS system D-glucose-specific IIA component, Glc family; 'PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1'; 'TIGRFAM: PTS system, glucose subfamily, IIA component'; TC 4.A.1.1.1. (169 aa)
Sps_00717UTP-hexose-1-phosphate uridylyltransferase; 'PFAM: Galactose-1-phosphate uridyl transferase, C-terminal domain; Galactose-1-phosphate uridyl transferase, N-terminal domain'; 'TIGRFAM: galactose-1-phosphate uridylyltransferase, family 1'. (353 aa)
Sps_00786Phosphoglucomutase, alpha-D-glucose phosphate-specific; 'PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Phosphoglucomutase/phosphomannomutase, C-terminal domain; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I'; 'TIGRFAM: phosphoglucomutase, alpha-D-glucose phosphate-specific'. (554 aa)
Sps_00810Putative phosphatase; PFAM: Haloacid dehalogenase-like hydrolase; 'TIGRFAM: 2-phosphoglycolate phosphatase, prokaryotic'. (232 aa)
Sps_01355Chitinase; PFAM: Glycosyl hydrolases family 18; Carbohydrate binding domain. (917 aa)
nagZBeta-glucosidase-like glycosyl hydrolase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. (332 aa)
Sps_01966Phosphomannomutase; 'PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Phosphoglucomutase/phosphomannomutase, C-terminal domain; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I'. (573 aa)
Sps_02142Hypothetical protein; 'PFAM: Phosphotransferase system, EIIC; phosphotransferase system, EIIB'; 'TIGRFAM: PTS system, glucose-like IIB component'. (489 aa)
glgCGlucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (422 aa)
Sps_02362PFAM: Amidohydrolase family; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase; Belongs to the metallo-dependent hydrolases superfamily. NagA family. (377 aa)
Sps_02363Putative N-acetylglucosamine kinase; PFAM: BadF/BadG/BcrA/BcrD ATPase family. (298 aa)
Sps_02364N-acetyl-beta-hexosaminidase; 'PFAM: Putative carbohydrate binding domain; Glycosyl hydrolase family 20, catalytic domain; Glycosyl hydrolase family 20, domain 2; Chitobiase/beta-hexosaminidase C-terminal domain'. (888 aa)
pgiPFAM: Phosphoglucose isomerase; Belongs to the GPI family. (545 aa)
Sps_02581'PFAM: Glycosyl hydrolases family 18; Carbohydrate binding domain; Chitinase A, N-terminal domain'. (863 aa)
galKGalactokinase; Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily. (388 aa)
Sps_03256Mannose-1-phosphate guanylyltransferase (GDP); PFAM: Nucleotidyl transferase; Mannose-6-phosphate isomerase; TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; mannose-6-phosphate isomerase, type 2. (479 aa)
Sps_03257Phosphomannomutase; 'PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Phosphoglucomutase/phosphomannomutase, C-terminal domain; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I'. (480 aa)
Sps_03667UDP-glucose pyrophosphorylase; PFAM: Nucleotidyl transferase; TIGRFAM: UTP--glucose-1-phosphate uridylyltransferase. (307 aa)
Sps_03668UDP-galactose 4-epimerase; PFAM: NAD dependent epimerase/dehydratase family; UDP-glucose 4-epimerase C-term subunit; TIGRFAM: UDP-glucose-4-epimerase GalE; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (337 aa)
Sps_03673N-acetylglucosamine kinase; PFAM: ROK family. (322 aa)
Sps_03694Nucleoside-diphosphate-sugar pyrophosphorylase family protein; PFAM: Nucleotidyl transferase; Bacterial transferase hexapeptide (six repeats). (472 aa)
Sps_03721PFAM: NAD dependent epimerase/dehydratase family. (309 aa)
Sps_03723CDP-glucose 4,6-dehydratase; PFAM: NAD dependent epimerase/dehydratase family; 'TIGRFAM: CDP-glucose 4,6-dehydratase'. (366 aa)
Sps_03724PFAM: Nucleotidyl transferase; TIGRFAM: glucose-1-phosphate cytidylyltransferase. (256 aa)
Sps_03727Acetyltransferase (isoleucine patch superfamily); PFAM: Bacterial transferase hexapeptide (six repeats). (153 aa)
Sps_04137Chitinase; PFAM: Glycosyl hydrolases family 18; Carbohydrate binding domain. (861 aa)
glmMPhosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. (463 aa)
Sps_04639PFAM: Nucleotidyl transferase. (228 aa)
Sps_04640PFAM: Phosphotransferase enzyme family. (337 aa)
nagBGlucosamine-6-phosphate isomerase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. (263 aa)
murAUDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (419 aa)
glmSGlutamine--fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (609 aa)
glmUUDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (454 aa)
Your Current Organism:
Shewanella psychrophila
NCBI taxonomy Id: 225848
Other names: CGMCC 1.6159, JCM 13876, S. psychrophila, Shewanella psychrophila Xiao et al. 2007 emend. Thorell et al. 2019, Shewanella sp. WP2, strain WP2
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.