STRINGSTRING
moaA moaA Sps_00167 Sps_00167 mobA mobA Sps_00758 Sps_00758 queE queE queC queC Sps_01390 Sps_01390 Sps_01714 Sps_01714 Sps_01755 Sps_01755 ribA ribA queF queF Sps_02323 Sps_02323 Sps_02324 Sps_02324 Sps_02546 Sps_02546 Sps_02547 Sps_02547 Sps_02613 Sps_02613 Sps_02690 Sps_02690 Sps_02901 Sps_02901 folE folE Sps_03509 Sps_03509 Sps_03573 Sps_03573 Sps_03665 Sps_03665 Sps_03666 Sps_03666 ribB ribB Sps_04255 Sps_04255 Sps_04986 Sps_04986 Sps_05071 Sps_05071 Sps_05475 Sps_05475 Sps_05497 Sps_05497 moaC moaC moaA-2 moaA-2 Sps_05619 Sps_05619
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
moaAMolybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (328 aa)
Sps_00167Molybdopterin-guanine dinucleotide biosynthesis protein MobB; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. (599 aa)
mobAMolybdenum cofactor guanylyltransferase; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family. (196 aa)
Sps_00758Aminodeoxychorismate synthase, subunit I; 'PFAM: chorismate binding enzyme; Anthranilate synthase component I, N terminal region'; 'TIGRFAM: aminodeoxychorismate synthase, component I, bacterial clade'. (464 aa)
queEPutative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (222 aa)
queCpreQ(0) biosynthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. (229 aa)
Sps_01390PFAM: Aminotransferase class IV; TIGRFAM: aminodeoxychorismate lyase. (275 aa)
Sps_01714Putative MobA-like protein; PFAM: MobA-like NTP transferase domain. (218 aa)
Sps_01755Folylpolyglutamate synthase/dihydrofolate synthase; 'PFAM: Mur ligase family, glutamate ligase domain; Mur ligase middle domain'; TIGRFAM: folylpolyglutamate synthase/dihydrofolate synthase; Belongs to the folylpolyglutamate synthase family. (423 aa)
ribAGTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. (205 aa)
queF7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). (285 aa)
Sps_02323PFAM: Alkaline phosphatase; Belongs to the alkaline phosphatase family. (499 aa)
Sps_02324PFAM: Alkaline phosphatase; Belongs to the alkaline phosphatase family. (531 aa)
Sps_02546'PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)'; TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase. (173 aa)
Sps_02547Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (127 aa)
Sps_02613PFAM: PhoD-like phosphatase. (590 aa)
Sps_02690Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (160 aa)
Sps_02901PFAM: Alkaline phosphatase; Belongs to the alkaline phosphatase family. (450 aa)
folEPFAM: GTP cyclohydrolase I; TIGRFAM: GTP cyclohydrolase I. (219 aa)
Sps_03509Metal-dependent hydrolase, beta-lactamase superfamily II; PFAM: Metallo-beta-lactamase superfamily. (281 aa)
Sps_03573FolB domain protein; PFAM: Dihydroneopterin aldolase; TIGRFAM: dihydroneopterin aldolase; FolB domain. (124 aa)
Sps_03665PFAM: Pterin 4 alpha carbinolamine dehydratase. (112 aa)
Sps_03666Phenylalanine 4-hydroxylase; PFAM: Biopterin-dependent aromatic amino acid hydroxylase; 'TIGRFAM: phenylalanine-4-hydroxylase, monomeric form'. (265 aa)
ribB3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. (367 aa)
Sps_04255Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (280 aa)
Sps_04986'PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)'; TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase. (163 aa)
Sps_05071PFAM: Glutamine amidotransferase class-I; TIGRFAM: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase. (193 aa)
Sps_05475Molybdopterin molybdochelatase; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. (414 aa)
Sps_05497Molybdopterin synthase subunit MoaE; PFAM: MoaE protein. (155 aa)
moaCCyclic pyranopterin monophosphate synthase subunit MoaC; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. (158 aa)
moaA-2Cyclic pyranopterin monophosphate synthase subunit MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (326 aa)
Sps_05619PFAM: Probable molybdopterin binding domain; TIGRFAM: molybdenum cofactor synthesis domain. (177 aa)
Your Current Organism:
Shewanella psychrophila
NCBI taxonomy Id: 225848
Other names: CGMCC 1.6159, JCM 13876, S. psychrophila, Shewanella psychrophila Xiao et al. 2007 emend. Thorell et al. 2019, Shewanella sp. WP2, strain WP2
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.