STRINGSTRING
rpsF rpsF rpsR rpsR rplI rplI gltX gltX cysS cysS mrnC mrnC EF_0047 EF_0047 EF_0049 EF_0049 serS-1 serS-1 rpsL rpsL rpsG rpsG fusA fusA tuf tuf rpsJ rpsJ rplC rplC rplD rplD rplW rplW rplB rplB rpsS rpsS rplV rplV rpsC rpsC rplP rplP rpmC rpmC rpsQ rpsQ rplN rplN rplX rplX rplE rplE rpsN-1 rpsN-1 rpsH rpsH rplF rplF rplR rplR rpsE rpsE rpmD rpmD rplO rplO infA infA rpmJ rpmJ rpsM rpsM rpsK rpsK rpoA rpoA rplQ rplQ EF_0244 EF_0244 pth pth EF_0262 EF_0262 tilS tilS EF_0267 EF_0267 lysS lysS efp efp EF_0350 EF_0350 EF_0482 EF_0482 EF_0513 EF_0513 rpmF-1 rpmF-1 rpsN-2 rpsN-2 rpmF-2 rpmF-2 rpmG-1 rpmG-1 tryS-1 tryS-1 lplA-1 lplA-1 EF_0678 EF_0678 EF_0684 EF_0684 trmB trmB prfC prfC gatC gatC gatA gatA gatB gatB EF_0728 EF_0728 EF_0737 EF_0737 EF_0748 EF_0748 rpoN rpoN leuS leuS rplY rplY EF_0838 EF_0838 EF_0854 EF_0854 tgt tgt infC infC rpmI rpmI rplT rplT metG metG rnmV rnmV ksgA ksgA EF_0950 EF_0950 rplU rplU rpmA rpmA nusB nusB rsmH rsmH ileS ileS EF_1033 EF_1033 rpmF-3 rpmF-3 EF_1111 EF_1111 pheS pheS pheT pheT EF_1123 EF_1123 lipL lipL rpoE rpoE EF_1152 EF_1152 EF_1158 EF_1158 rho rho rpmE rpmE rnj rnj EF_1197 EF_1197 EF_1203 EF_1203 EF_1249 EF_1249 nusA nusA infB infB rbfA rbfA EF_1368 EF_1368 alaS alaS EF_1380 EF_1380 EF_1433 EF_1433 EF_1450 EF_1450 EF_1477 EF_1477 sigA sigA RpsA RpsA papS papS queG queG gid gid EF_1651 EF_1651 EF_1654 EF_1654 EF_1678 EF_1678 rnz rnz rpsP rpsP pyrR pyrR EF_1730 EF_1730 tryS-2 tryS-2 EF_1827 EF_1827 EF_1850 EF_1850 rplS rplS trmD trmD rimM rimM EF_1937 EF_1937 aspS aspS hisS hisS EF_1975 EF_1975 EF_2036 EF_2036 rlmN rlmN trmU trmU miaA miaA tadA tadA EF_2228 EF_2228 EF_2290 EF_2290 EF_2349 EF_2349 lepA lepA asnS asnS proS proS frr frr tsf tsf rpsB rpsB EF_2400 EF_2400 acyP acyP glyS glyS glyQ glyQ ybeY ybeY rpsU rpsU rpsT rpsT EF_2452 EF_2452 EF_2460 EF_2460 argS argS gcp gcp EF_2473 EF_2473 EF_2474 EF_2474 EF_2475 EF_2475 EF_2478 EF_2478 EF_2552 EF_2552 prfA prfA EF_2566 EF_2566 smpB smpB EF_2637 EF_2637 EF_2643 EF_2643 EF_2665 EF_2665 trpS trpS EF_2706 EF_2706 rplL rplL rplJ rplJ rplA rplA rplK rplK nusG nusG rpmG-2 rpmG-2 EF_2740 EF_2740 lplA-2 lplA-2 EF_2742 EF_2742 rsmI rsmI EF_2787 EF_2787 EF_2828 EF_2828 rpmG-3 rpmG-3 thrS thrS tmcAL tmcAL EF_2872 EF_2872 EF_2894 EF_2894 EF_2904 EF_2904 EF_2923 EF_2923 rnj-2 rnj-2 valS valS thiI thiI EF_2976 EF_2976 EF_2983 EF_2983 EF_2988 EF_2988 EF_2989 EF_2989 EF_2990 EF_2990 EF_3020 EF_3020 rlmH rlmH EF_3028 EF_3028 pnpA pnpA rpsO rpsO def-1 def-1 rpsD rpsD EF_3073 EF_3073 EF_3079 EF_3079 rnc rnc rpmB rpmB sun sun fmt fmt rpoZ rpoZ EF_3131 EF_3131 EF_3161 EF_3161 EF_3180 EF_3180 rpsN-3 rpsN-3 rpmG-4 rpmG-4 EF_3207 EF_3207 rpsI rpsI EF_3236 EF_3236 rpoC rpoC rpoB rpoB birA birA serS-2 serS-2 gidB gidB gidA gidA trmE trmE rnpA rnpA rpmH rpmH
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
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Predicted Interactions
gene neighborhood
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rpsFRibosomal protein S6; Binds together with S18 to 16S ribosomal RNA. (100 aa)
rpsRRibosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. (79 aa)
rplIRibosomal protein L9; Binds to the 23S rRNA. (150 aa)
gltXglutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (485 aa)
cysScysteinyl-tRNA synthetase; Similar to GB:M82962, SP:Q16819, and PID:535475; identified by sequence similarity; putative; Belongs to the class-I aminoacyl-tRNA synthetase family. (470 aa)
mrnCConserved hypothetical protein; Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors; Belongs to the MrnC RNase family. (132 aa)
EF_0047RNA methyltransferase, TrmH family; Identified by match to TIGR protein family HMM TIGR00185; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. (282 aa)
EF_0049Sigma-70 factor family protien; Similar to GP:10172727, GB:L04284, GB:D14540, GB:S66432, GB:L01986, GB:S78571, GB:U04737, SP:Q03164, PID:184394, PID:451555, PID:553800, and PID:899268; identified by sequence similarity; putative; Belongs to the sigma-70 factor family. (188 aa)
serS-1seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (423 aa)
rpsLRibosomal protein S12; With S4 and S5 plays an important role in translational accuracy. (137 aa)
rpsGRibosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. (156 aa)
fusATranslation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...] (693 aa)
tufTranslation elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (395 aa)
rpsJRibosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (102 aa)
rplCRibosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. (209 aa)
rplDRibosomal protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. (207 aa)
rplWRibosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family. (96 aa)
rplBRibosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (276 aa)
rpsSRibosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (92 aa)
rplVRibosomal protein L22; This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity). (115 aa)
rpsCRibosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. (218 aa)
rplPRibosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. (144 aa)
rpmCRibosomal protein L29; Similar to GB:M19169, GB:J03870, SP:P01037, PID:337752, and PID:386825; identified by sequence similarity; putative; Belongs to the universal ribosomal protein uL29 family. (62 aa)
rpsQRibosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (88 aa)
rplNRibosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (122 aa)
rplXRibosomal protein L24; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. (103 aa)
rplERibosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (179 aa)
rpsN-1Ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site. (61 aa)
rpsHRibosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (132 aa)
rplFRibosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (178 aa)
rplRRibosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (118 aa)
rpsERibosomal protein S5; With S4 and S12 plays an important role in translational accuracy; Belongs to the universal ribosomal protein uS5 family. (166 aa)
rpmDRibosomal protein L30; Similar to SP:P19947, GB:M15400, GB:L11910, GB:M27845, GB:M27846, GB:M27847, GB:M27848, GB:M27849, GB:M27850, GB:M27851, GB:L35146, GB:M27852, GB:M27853, GB:M27854, GB:M27855, GB:M27856, GB:M27857, GB:M27858, GB:M27859, GB:M27860, GB:L35147, GB:M27862, GB:M27863, GB:M27864, GB:M27865, GB:M27866, GB:M28419, GB:M33647, GB:L41892, GB:L41915, GB:L41921, GB:L41904, GB:L41898, GB:L41923, GB:L42000, GB:L41891, GB:L49214, GB:L41897, GB:L49215, GB:L49216, GB:L41899, GB:L49233, GB:L41911, GB:L41890, GB:L41894, GB:L41900, GB:S67080, SP:P06400, PID:1088319, PID:1088325, PID: [...] (59 aa)
rplORibosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (146 aa)
infATranslation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. (72 aa)
rpmJRibosomal protein L36; Identified by match to PFAM protein family HMM PF00444; Belongs to the bacterial ribosomal protein bL36 family. (38 aa)
rpsMRibosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family. (121 aa)
rpsKRibosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. (129 aa)
rpoADNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (312 aa)
rplQRibosomal protein L17; Similar to SP:P20277; identified by sequence similarity; putative. (127 aa)
EF_0244Acetyltransferase, GNAT family; Identified by match to TIGR protein family HMM TIGR01575. (163 aa)
pthpeptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. (188 aa)
EF_0262S1 RNA-binding domain protein; Similar to GB:X66533, SP:Q02153, and PID:31686; identified by sequence similarity; putative. (159 aa)
tilSConserved domain protein; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (462 aa)
EF_0267Zinc-binding TIM-barrel protein, nifR3 family, putative; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. (332 aa)
lysSlysyl-tRNA synthetase; Similar to GB:Z21958, GB:M25668, GB:L12563, GB:U01828, SP:P11137, GB:U32995, GB:U34059, GB:U34061, GB:U34064, GB:U34065, GB:U34069, GB:U34060, GB:U34062, GB:U34063, GB:U34066, PID:1850617, PID:187381, and PID:409875; identified by sequence similarity; putative; Belongs to the class-II aminoacyl-tRNA synthetase family. (498 aa)
efpTranslation elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. (186 aa)
EF_0350Conserved hypothetical protein; Similar to GP:1353561; identified by sequence similarity; putative. (361 aa)
EF_0482Conserved hypothetical protein; Similar to GB:X04470, GB:X04503, GB:X04502, SP:P03973, PID:28639, PID:338233, PID:36491, and PID:758101; identified by sequence similarity; putative. (133 aa)
EF_0513Conserved hypothetical protein TIGR00053; Similar to GP:6175622; identified by sequence similarity; putative. (91 aa)
rpmF-1Ribosomal protein L32; Similar to SP:Q9CJA6; identified by sequence similarity; putative; Belongs to the bacterial ribosomal protein bL32 family. (57 aa)
rpsN-2Ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family. (89 aa)
rpmF-2Ribosomal protein L32; Similar to SP:O34101; identified by sequence similarity; putative; Belongs to the bacterial ribosomal protein bL32 family. (59 aa)
rpmG-1Ribosomal protein L33; Similar to GB:M94579, GB:S70516, GB:S40178, GB:S79774, SP:P19835, PID:1567198, PID:180244, PID:187150, and PID:29501; identified by sequence similarity; putative; Belongs to the bacterial ribosomal protein bL33 family. (49 aa)
tryS-1tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. (418 aa)
lplA-1Lipoate-protein ligase A; Similar to SP:P26997, and PID:217186; identified by sequence similarity; putative. (337 aa)
EF_0678Acetyltransferase, GNAT family; Similar to GP:10174740; identified by sequence similarity; putative. (184 aa)
EF_0684Cmp-binding protein, putative; Similar to GB:X78998, PID:1016368, and PID:475934; identified by sequence similarity; putative. (314 aa)
trmBMethyltransferase, putative; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. (214 aa)
prfCPeptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily. (524 aa)
gatCglutamyl-tRNA(Gln) amidotransferase, C subunit; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family. (101 aa)
gatAglutamyl-tRNA(Gln) amidotransferase, A subunit; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). (489 aa)
gatBglutamyl-tRNA(Gln) amidotransferase, B subunit; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily. (476 aa)
EF_0728RNA methyltransferase, TrmA family; Similar to GP:10173301; identified by sequence similarity; putative; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (457 aa)
EF_0737Amidase, putative; Similar to GB:L23970, SP:P40593, GB:M80522, PID:142316, and PID:398002; identified by sequence similarity; putative. (528 aa)
EF_0748Rhodanese family protein; Similar to GP:2565150; identified by sequence similarity; putative; Belongs to the UPF0176 family. (316 aa)
rpoNRNA polymerase sigma-54 factor; Similar to GB:S51768, GB:D13510, GB:L15533, GB:X68641, SP:Q06141, PID:189601, PID:285971, PID:312807, PID:482909, GB:D00937, SP:P33651, PID:216998, and PID:46881; identified by sequence similarity; putative. (437 aa)
leuSleucyl-tRNA synthetase; Similar to SP:P14878, GB:X06083, and PID:43373; identified by sequence similarity; putative; Belongs to the class-I aminoacyl-tRNA synthetase family. (804 aa)
rplYRibosomal protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily. (202 aa)
EF_0838Pyridoxal phosphate-dependent enzyme, putative; Similar to SP:Q98FF1; identified by sequence similarity; putative. (368 aa)
EF_0854Signal peptidase I; Similar to GP:10173645; identified by sequence similarity; putative; Belongs to the peptidase S26 family. (241 aa)
tgtQueuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form th [...] (381 aa)
infCTranslation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins. (173 aa)
rpmIRibosomal protein L35; Similar to SP:P55874; identified by sequence similarity; putative; Belongs to the bacterial ribosomal protein bL35 family. (66 aa)
rplTRibosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. (119 aa)
metGmethionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily. (669 aa)
rnmVPrimase-related protein; Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step; Belongs to the ribonuclease M5 family. (190 aa)
ksgADimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. (295 aa)
EF_0950Conserved hypothetical protein TIGR00150; Similar to GP:10173158; identified by sequence similarity; putative. (159 aa)
rplURibosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. (102 aa)
rpmARibosomal protein L27; Similar to SP:P19663; identified by sequence similarity; putative; Belongs to the bacterial ribosomal protein bL27 family. (95 aa)
nusBN utilization substance protein B; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. (154 aa)
rsmHConserved hypothetical protein TIGR00006; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. (319 aa)
ileSisoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. (926 aa)
EF_10336-aminohexanoate-cyclic-dimer hydrolase, putative; Similar to SP:P13397, GB:U03161, SP:P42512, and PID:454353; identified by sequence similarity; putative; Belongs to the amidase family. (729 aa)
rpmF-3Ribosomal protein L32; Similar to SP:O34687; identified by sequence similarity; putative; Belongs to the bacterial ribosomal protein bL32 family. (59 aa)
EF_1111Signal peptidase I; Similar to GB:L22647, SP:P34995, PID:410209, GB:M89470, GB:L25597, SP:Q02962, PID:438650, and PID:553607; identified by sequence similarity; putative; Belongs to the peptidase S26 family. (182 aa)
pheSphenylalanyl-tRNA synthetase, alpha subunit; Similar to SP:P37279, and PID:435125; identified by sequence similarity; putative; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. (348 aa)
pheTphenylalanyl-tRNA synthetase, beta subunit; Similar to GB:J04809, SP:P00568, and PID:178322; identified by sequence similarity; putative; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (807 aa)
EF_1123Conserved hypothetical protein; Similar to GP:10175688; identified by sequence similarity; putative. (170 aa)
lipLLipoate-protein ligase A family protein, putative; Catalyzes the amidotransfer (transamidation) of the lipoyl moiety from lipoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes. Takes part in a pathway for scavenging of lipoic acid; Belongs to the octanoyltransferase LipL family. (283 aa)
rpoEDNA-directed RNA polymerase, delta subunit, putative; Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling; Belongs to the RpoE family. (208 aa)
EF_1152Conserved hypothetical protein; Similar to GB:X74614, SP:Q14990, PID:474426, GB:X74614, SP:Q14990, and PID:474426; identified by sequence similarity; putative; Belongs to the methyltransferase superfamily. (387 aa)
EF_1158Similar to GB:U07225, SP:P41231, and PID:984507; identified by sequence similarity; putative. (307 aa)
rhoTranscription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (430 aa)
rpmERibosomal protein L31; Similar to GB:X66113, SP:Q01780, and PID:35555; identified by sequence similarity; putative. (89 aa)
rnjMetallo-beta-lactamase superfamily protein; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay. (562 aa)
EF_1197Metallo-beta-lactamase YycJ; Similar to GP:6687474, and GP:6687474; identified by sequence similarity; putative. (268 aa)
EF_1203Conserved hypothetical protein TIGR00250; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF nuclease family. (140 aa)
EF_1249Fibronectin/fibrinogen-binding protein, putative; Similar to GP:6175915, and GP:19110786; identified by sequence similarity; putative. (570 aa)
nusAN utilization substance protein A; Participates in both transcription termination and antitermination. (399 aa)
infBTranslation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. (798 aa)
rbfARibosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. (116 aa)
EF_1368Conserved hypothetical protein; Identified by Glimmer2; putative. (373 aa)
alaSalanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (880 aa)
EF_1380Conserved hypothetical protein; Similar to GP:10173995; identified by sequence similarity; putative. (238 aa)
EF_1433Conserved hypothetical protein; Similar to GP:3341952; identified by sequence similarity; putative. (233 aa)
EF_1450Positive control factor, putative. (194 aa)
EF_1477Conserved hypothetical protein; Identified by Glimmer2; putative. (110 aa)
sigARNA polymerase sigma-43 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (368 aa)
RpsARibosomal protein S1; Identified by match to TIGR protein family HMM TIGR00448. (403 aa)
papSPoly A polymerase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. (406 aa)
queGIron-sulfur cluster-binding protein, putative; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family. (389 aa)
gidGlucose-inhibited division protein; Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs; Belongs to the MnmG family. TrmFO subfamily. (435 aa)
EF_1651Abortive infection protein; Identified by match to PFAM protein family HMM PF04186. (217 aa)
EF_1654GTPase of unknown function; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. (283 aa)
EF_1678Signal peptidase I; Identified by match to PFAM protein family HMM PF00461; Belongs to the peptidase S26 family. (184 aa)
rnzMetallo-beta-lactamase, AtsA/ElaC family; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family. (313 aa)
rpsPRibosomal protein S16; Similar to SP:P21474; identified by sequence similarity; putative; Belongs to the bacterial ribosomal protein bS16 family. (91 aa)
pyrRPyrimidine operon regulatory protein PyrR; Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines, by binding to the anti-antiterminator region of the 5' leader on pyr mRNA. This probably favors formation of a transcription terminator hairpin, leading to a reduced expression of downstream genes (By similarity). Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily. (178 aa)
EF_1730EbsC protein; Affects the expression of the receptor, named binding substance, that mediates mating aggregate formation. Could be a regulatory protein that suppresses the function or expression of ebsA and/or ebsMB. (164 aa)
tryS-2tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. (420 aa)
EF_1827Conserved hypothetical protein; Identified by match to TIGR protein family HMM TIGR00299; Belongs to the LarC family. (326 aa)
EF_1850Conserved hypothetical protein; Similar to GB:X04470, GB:X04503, GB:X04502, SP:P03973, PID:28639, PID:338233, PID:36491, and PID:758101; identified by sequence similarity; putative. (133 aa)
rplSRibosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. (115 aa)
trmDtRNA (guanine-N1)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. (246 aa)
rimM16S rRNA processing protein RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family. (174 aa)
EF_1937Conserved hypothetical protein; Similar to GP:10174486, and GP:10174486; identified by sequence similarity; putative. (178 aa)
aspSaspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (589 aa)
hisShistidyl-tRNA synthetase; Similar to GB:M64676, and PID:338077; identified by sequence similarity; putative. (433 aa)
EF_1975Conserved hypothetical protein TIGR00046; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. (250 aa)
EF_2036Hypothetical protein; Identified by Glimmer2; putative. (62 aa)
rlmNConserved hypothetical protein TIGR00048; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family. (357 aa)
trmUtRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (374 aa)
miaAtRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (309 aa)
tadACytidine/deoxycytidylate deaminase family protein; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. (173 aa)
EF_2228tryptophanyl-tRNA synthetase; Similar to GB:M26405, SP:P21206, PID:155450, PID:2300613, and PID:2300615; identified by sequence similarity; putative; Belongs to the class-I aminoacyl-tRNA synthetase family. (334 aa)
EF_2290RNA polymerase sigma-70 factor, ECF subfamily; Identified by match to PFAM protein family HMM PF00140. (126 aa)
EF_2349Hypothetical protein; Identified by Glimmer2; putative. (459 aa)
lepAGTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. (611 aa)
asnSasparaginyl-tRNA synthetase; Similar to GB:X03795, GB:M19989, GB:M21571, GB:M19984, GB:M19985, GB:M19986, GB:M19987, GB:M19988, GB:A09204, GB:S62078, SP:P04085, PID:2294398, PID:2294423, PID:2297381, PID:35364, PID:35366, PID:387007, PID:387008, and PID:412189; identified by sequence similarity; putative. (450 aa)
proSprolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...] (572 aa)
frrRibosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. (185 aa)
tsfTranslation elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family. (293 aa)
rpsBRibosomal protein S2; Similar to SP:P21464; identified by sequence similarity; putative; Belongs to the universal ribosomal protein uS2 family. (261 aa)
EF_2400RNA methyltransferase, TrmH family; Similar to GP:10175734; identified by sequence similarity; putative; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. (258 aa)
acyPAcylphosphatase; Similar to SP:P31827, GB:X71917, PID:311346, GB:U00096, and PID:1787771; identified by sequence similarity; putative. (91 aa)
glySglycyl-tRNA synthetase, beta subunit; Similar to GB:U04815, GB:U04818, GB:U04824, GB:U04816, GB:U04817, SP:P21127, PID:189481, PID:507158, PID:507160, PID:507162, PID:507164, PID:507166, PID:507168, PID:507427, and PID:507429; identified by sequence similarity; putative. (694 aa)
glyQglycyl-tRNA synthetase, alpha subunit; Similar to GB:X59871, GB:X59869, GB:X59870, SP:P36402, PID:36788, PID:619882, and PID:619884; identified by sequence similarity; putative. (302 aa)
ybeYConserved hypothetical protein TIGR00043; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. (159 aa)
rpsURibosomal protein S21; Similar to GP:5689043, and SP:P21478; identified by sequence similarity; putative; Belongs to the bacterial ribosomal protein bS21 family. (58 aa)
rpsTRibosomal protein S20; Binds directly to 16S ribosomal RNA. (83 aa)
EF_2452Methylase, putative; Similar to GP:10175211; identified by sequence similarity; putative. (184 aa)
EF_2460GTP-binding protein TypA; Similar to SP:Q05489, PID:49206, PID:640960, and PID:1247764; identified by sequence similarity; putative. (611 aa)
argSarginyl-tRNA synthetase; Similar to GB:L10981, GB:L10981, PID:432192, GB:L10981, GB:L10981, and PID:432192; identified by sequence similarity; putative. (563 aa)
gcpO-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. (348 aa)
EF_2473Ribosomal-protein-alanine acetyltransferase, putative; Acetylates the N-terminal alanine of ribosomal protein S18. (154 aa)
EF_2474Ribosomal-protein-alanine acetyltransferase, putative; Acetylates the N-terminal alanine of ribosomal protein S18. (155 aa)
EF_2475Conserved hypothetical protein; Similar to GP:3341437; identified by sequence similarity; putative. (251 aa)
EF_2478Conserved hypothetical protein; Similar to GP:3341435; identified by sequence similarity; putative. (381 aa)
EF_2552Sua5/YciO/YrdC/YwlC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. (340 aa)
prfAPeptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. (357 aa)
EF_2566Conserved hypothetical protein; Identified by match to PFAM protein family HMM PF01206; Belongs to the sulfur carrier protein TusA family. (195 aa)
smpBSsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...] (154 aa)
EF_2637Abortive infection protein; Identified by match to PFAM protein family HMM PF04226. (217 aa)
EF_2643Conserved hypothetical protein; Identified by Glimmer2; putative. (236 aa)
EF_2665RNA methyltransferase, TrmH family; Could methylate the ribose at the nucleotide 34 wobble position in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily. (168 aa)
trpStryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. (336 aa)
EF_2706RNA methyltransferase, TrmA family; Similar to SP:Q05373, and PID:49227; identified by sequence similarity; putative; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (456 aa)
rplLRibosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family. (122 aa)
rplJRibosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (166 aa)
rplARibosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. (229 aa)
rplKRibosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. (140 aa)
nusGTranscription antitermination protein NusG; Participates in transcription elongation, termination and antitermination. (181 aa)
rpmG-2Ribosomal protein L33; Similar to GB:M96982, SP:Q01081, and PID:338263; identified by sequence similarity; putative; Belongs to the bacterial ribosomal protein bL33 family. (50 aa)
EF_2740O-methyltransferase family protein; Similar to GB:M23689, SP:P16946, GB:M31790, GB:U20827, GB:U20828, GB:U20830, GB:U20836, GB:U20849, GB:U20850, GB:U20852, PID:153619, PID:153698, and PID:694098; identified by sequence similarity; putative. (229 aa)
lplA-2Lipoate-protein ligase A; Similar to GP:10173297, and SP:P32099; identified by sequence similarity; putative. (334 aa)
EF_2742Conserved hypothetical protein; Similar to SP:P26997, PID:217186, SP:P26997, and PID:217186; identified by sequence similarity; putative. (246 aa)
rsmITetrapyrrole methylase family protein; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. (290 aa)
EF_2787Rhodanese family protein; Similar to GB:M36711, GB:M61156, GB:X77343, and SP:P05549; identified by sequence similarity; putative. (132 aa)
EF_2828Transcriptional regulator, ArpU family; Identified by match to TIGR protein family HMM TIGR01637. (155 aa)
rpmG-3Ribosomal protein L33; Similar to GB:M94579, GB:S70516, GB:S40178, GB:S79774, SP:P19835, PID:1567198, PID:180244, PID:187150, and PID:29501; identified by sequence similarity; putative; Belongs to the bacterial ribosomal protein bL33 family. (49 aa)
thrSthreonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr). (645 aa)
tmcALConserved hypothetical protein; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac- AMP) and then transfers the acetyl group to tRNA to form ac(4)C34. (392 aa)
EF_2872Conserved hypothetical protein TIGR00253; Similar to GP:10173941; identified by sequence similarity; putative. (103 aa)
EF_2894General stress protein 13, putative; Similar to SP:P80870, SP:P13295, GB:X15079, PID:48691, and PID:49406; identified by sequence similarity; putative. (122 aa)
EF_2904Hypothetical protein; Identified by Glimmer2; putative. (429 aa)
EF_2923Conserved hypothetical protein; Similar to GP:10175282; identified by sequence similarity; putative; Belongs to the UPF0356 family. (70 aa)
rnj-2Metallo-beta-lactamase superfamily protein; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay. (561 aa)
valSvalyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (880 aa)
thiIThiazole biosynthesis protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (404 aa)
EF_2976Pyridoxal phosphate-dependent enzyme, putative; Identified by match to PFAM protein family HMM PF01053. (367 aa)
EF_2983glutamyl-tRNA(Gln) amidotransferase, A subunit, putative; Similar to GB:U03161, SP:P42512, and PID:454353; identified by sequence similarity; putative; Belongs to the amidase family. (482 aa)
EF_2988Identified by match to PFAM protein family HMM PF00581. (99 aa)
EF_2989Coenzyme A disulfide reductase; Identified by match to PFAM protein family HMM PF02852. (549 aa)
EF_2990Identified by match to PFAM protein family HMM PF00581. (104 aa)
EF_3020Conserved hypothetical protein; Similar to GP:2947297, and GP:2947297; identified by sequence similarity; putative; Belongs to the sigma-70 factor family. ECF subfamily. (154 aa)
rlmHConserved hypothetical protein TIGR00246; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. (159 aa)
EF_3028Putative tRNA-binding domain protein; Similar to GP:10175874; identified by sequence similarity; putative; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (206 aa)
pnpAPolyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (704 aa)
rpsORibosomal protein S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA. (89 aa)
def-1Polypeptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. (187 aa)
rpsDRibosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (203 aa)
EF_3073Signal peptidase I; Similar to SP:P27369, PID:154510, GB:D90402, GB:M74921, GB:S57283, GB:D13162, GB:D13163, GB:D13164, GB:D13165, GB:D13166, GB:D13167, GB:D13168, GB:S44866, SP:P24530, PID:181959, PID:182276, PID:219652, PID:285926, GB:D90402, GB:M74921, GB:S57283, GB:D13162, GB:D13163, GB:D13164, GB:D13165, GB:D13166, GB:D13167, GB:D13168, GB:S44866, SP:P24530, PID:181959, PID:182276, PID:219652, and PID:285926; identified by sequence similarity; putative; Belongs to the peptidase S26 family. (178 aa)
EF_3079Acetyltransferase, GNAT family; Similar to GP:10173452; identified by sequence similarity; putative. (185 aa)
rncRibonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. (230 aa)
rpmBRibosomal protein L28; Identified by match to TIGR protein family HMM TIGR00009; Belongs to the bacterial ribosomal protein bL28 family. (62 aa)
sunSun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. (459 aa)
fmtmethionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. (313 aa)
rpoZDNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (99 aa)
EF_3131Conserved hypothetical protein TIGR00255; Similar to GP:10175134; identified by sequence similarity; putative. (294 aa)
EF_3161Hypothetical protein; Identified by Glimmer2; putative. (133 aa)
EF_3180RNA polymerase sigma-70 factor, ECF subfamily; Similar to SP:Q08434, GB:S61781, PID:975350, PID:1934778, PID:2231217, SP:Q08434, GB:S61781, PID:975350, PID:1934778, and PID:2231217; identified by sequence similarity; putative; Belongs to the sigma-70 factor family. ECF subfamily. (165 aa)
rpsN-3Ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family. (89 aa)
rpmG-4Ribosomal protein L33; Similar to GB:M14219, SP:P07585, PID:181170, and PID:609452; identified by sequence similarity; putative; Belongs to the bacterial ribosomal protein bL33 family. (49 aa)
EF_3207Dihydrouridine synthase family protein; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. (324 aa)
rpsIRibosomal protein S9; Similar to SP:P21470; identified by sequence similarity; putative; Belongs to the universal ribosomal protein uS9 family. (130 aa)
EF_3236Type III leader peptidase family; Similar to GB:D16670, SP:P37701, and PID:391654; identified by sequence similarity; putative. (230 aa)
rpoCDNA-directed RNA polymerase, beta-prime subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1217 aa)
rpoBDNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1207 aa)
birABirA bifunctional protein; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. (330 aa)
serS-2seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (423 aa)
gidBGlucose-inhibited division protein B; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family. (238 aa)
gidAGlucose-inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. (632 aa)
trmEtRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. (465 aa)
rnpARibonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. (118 aa)
rpmHRibosomal protein L34; Similar to GB:D14689, SP:P35658, PID:285957, GB:J03925, GB:J04145, GB:S52228, SP:P11215, PID:307114, PID:307148, and PID:386975; identified by sequence similarity; putative; Belongs to the bacterial ribosomal protein bL34 family. (44 aa)
Your Current Organism:
Enterococcus faecalis V583
NCBI taxonomy Id: 226185
Other names: E. faecalis V583, Enterococcus faecalis str. V583, Enterococcus faecalis strain V583
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