STRINGSTRING
EF_1706 EF_1706 EF_0029 EF_0029 EF_0117 EF_0117 metC metC EF_0371 EF_0371 tdc tdc EF_0838 EF_0838 EF_0891 EF_0891 EF_1037 EF_1037 EF_1314 EF_1314 EF_2072 EF_2072 aspB aspB EF_2392 EF_2392 EF_2426 EF_2426 glyA glyA EF_2568 EF_2568 EF_2895 EF_2895 EF_2976 EF_2976 EF_2994 EF_2994 EF_3284 EF_3284
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EF_1706Aminotransferase, class I; Similar to GP:6318592, and GP:6318592; identified by sequence similarity; putative. (392 aa)
EF_0029Aminotransferase, class II; Identified by match to TIGR protein family HMM TIGR01265. (404 aa)
EF_0117Transcriptional regulator, GntR family; Similar to SP:P32982; identified by sequence similarity; putative. (470 aa)
metCCystathionine beta-lyase; Similar to GP:6513595; identified by sequence similarity; putative. (378 aa)
EF_0371Aminotransferase, class V; Identified by match to PFAM protein family HMM PF00282. (381 aa)
tdcDecarboxylase, putative; Catalyzes the decarboxylation of L-tyrosine to produce tyramine. Plays a role in acid resistance since tyramine production via tyrosine decarboxylation appears to provide a cytosolic pH maintenance mechanism that helps the bacterium cope with acid stress such as that encountered in gastrointestinal tract (GIT) environments. Therefore, may contribute to the colonization of the human GIT by E.faecalis. (636 aa)
EF_0838Pyridoxal phosphate-dependent enzyme, putative; Similar to SP:Q98FF1; identified by sequence similarity; putative. (368 aa)
EF_0891Aspartate aminotransferase, putative; Similar to GB:M26130, SP:P31309, PID:153833, GB:M23442, GB:M13982, SP:P05112, PID:186337, PID:307061, PID:33832, and PID:673419; identified by sequence similarity; putative. (384 aa)
EF_1037L-aspartate beta-decarboxylase, putative; Similar to GP:14279103; identified by sequence similarity; putative. (536 aa)
EF_1314Aspartate aminotransferase, putative; Similar to GB:L05611, SP:Q04729, and PID:551706; identified by sequence similarity; putative. (405 aa)
EF_2072Aminotransferase, class V; Similar to GP:10173876; identified by sequence similarity; putative. (381 aa)
aspBAspartate aminotransferase; Similar to GP:6465901, GB:M23442, GB:M13982, SP:P05112, PID:186337, PID:307061, PID:33832, and PID:673419; identified by sequence similarity; putative. (399 aa)
EF_2392Aminotransferase, class V; Similar to SP:P35092, and SP:P35093; identified by sequence similarity; putative; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. (411 aa)
EF_2426Transcriptional regulator, GntR family; Identified by match to TIGR protein family HMM TIGR00858. (483 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (412 aa)
EF_2568Aminotransferase, class V; Similar to GP:10176681; identified by sequence similarity; putative. (382 aa)
EF_2895Aminotransferase, class II; Similar to GB:M72150, GB:J02907, GB:M57888, SP:P20718, PID:181157, PID:181164, PID:183155, PID:338430, GB:M72150, GB:J02907, GB:M57888, SP:P20718, PID:181157, PID:181164, PID:183155, and PID:338430; identified by sequence similarity; putative. (388 aa)
EF_2976Pyridoxal phosphate-dependent enzyme, putative; Identified by match to PFAM protein family HMM PF01053. (367 aa)
EF_2994Aminotransferase, class V; Identified by match to PFAM protein family HMM PF00266. (402 aa)
EF_3284Cystathionine gamma-synthase, putative; Similar to GB:U09072, SP:P01594, SP:P01602, SP:P01606, SP:P01609, SP:P01611, SP:P80362, PID:33319, PID:470556, PID:470562, PID:470576, PID:470592, PID:470594, PID:470596, PID:470598, PID:470600, PID:470602, PID:470604, PID:470606, PID:470608, PID:470610, PID:470612, PID:470618, PID:483882, PID:483884, PID:483886, PID:483892, PID:483908, PID:506423, PID:506425, PID:567134, PID:567136, PID:567138, PID:567148, PID:567154, PID:567158, PID:567168, PID:567172, PID:587326, PID:587328, PID:587330, PID:587332, PID:587334, PID:619602, PID:619603, PID:61961 [...] (395 aa)
Your Current Organism:
Enterococcus faecalis V583
NCBI taxonomy Id: 226185
Other names: E. faecalis V583, Enterococcus faecalis str. V583, Enterococcus faecalis strain V583
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