13 items (Enterococcus faecalis V583) - STRING interaction network

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	nagB	Glucosamine-6-phosphate isomerase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. (233 aa)
	lexA	Transcriptional repressor LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. (209 aa)
	codY	Transcriptional regulator CodY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; Belongs to the CodY family. (260 aa)
	pyraA	Carbamoyl-phosphate synthase, small subunit; Similar to GP:7688228, and SP:P25993; identified by sequence similarity; putative; Belongs to the CarA family. (359 aa)
	hrcA	Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. (347 aa)
	pyrC	Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. (427 aa)
	pyrB	Aspartate carbamoyltransferase; Similar to SP:P05654; identified by sequence similarity; putative; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (308 aa)
	nagA-2	N-acetylglucosamine-6-phosphate deacetylase; Identified by match to TIGR protein family HMM TIGR00221. (383 aa)
	recA	recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (348 aa)
	rpoB	DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1207 aa)
	ctsR	Transcriptional regulator CtsR; Similar to GP:7007430, GB:M25108, SP:P05106, and PID:386833; identified by sequence similarity; putative; Belongs to the CtsR family. (155 aa)
	nagA-1	N-acetylglucosamine-6-phosphate deacetylase; Identified by match to TIGR protein family HMM TIGR00221. (382 aa)
	EF_0451	Glucosamine-6-phosphate isomerase, putative; Identified by match to TIGR protein family HMM TIGR01198. (232 aa)

Your Current Organism:

Enterococcus faecalis V583

NCBI taxonomy Id: 226185
Other names: E. faecalis V583, Enterococcus faecalis str. V583, Enterococcus faecalis strain V583

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EF_0451	nagA-1	EF_0451	EF_1317	Glucosamine-6-phosphate isomerase, putative; Identified by match to TIGR protein family HMM TIGR01198.	N-acetylglucosamine-6-phosphate deacetylase; Identified by match to TIGR protein family HMM TIGR00221.	0.982
EF_0451	nagA-2	EF_0451	EF_3044	Glucosamine-6-phosphate isomerase, putative; Identified by match to TIGR protein family HMM TIGR01198.	N-acetylglucosamine-6-phosphate deacetylase; Identified by match to TIGR protein family HMM TIGR00221.	0.986
EF_0451	pyraA	EF_0451	EF_1717	Glucosamine-6-phosphate isomerase, putative; Identified by match to TIGR protein family HMM TIGR01198.	Carbamoyl-phosphate synthase, small subunit; Similar to GP:7688228, and SP:P25993; identified by sequence similarity; putative; Belongs to the CarA family.	0.454
codY	ctsR	EF_1645	EF_3283	Transcriptional regulator CodY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; Belongs to the CodY family.	Transcriptional regulator CtsR; Similar to GP:7007430, GB:M25108, SP:P05106, and PID:386833; identified by sequence similarity; putative; Belongs to the CtsR family.	0.467
codY	lexA	EF_1645	EF_1579	Transcriptional regulator CodY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; Belongs to the CodY family.	Transcriptional repressor LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.	0.451
ctsR	codY	EF_3283	EF_1645	Transcriptional regulator CtsR; Similar to GP:7007430, GB:M25108, SP:P05106, and PID:386833; identified by sequence similarity; putative; Belongs to the CtsR family.	Transcriptional regulator CodY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; Belongs to the CodY family.	0.467
ctsR	hrcA	EF_3283	EF_1306	Transcriptional regulator CtsR; Similar to GP:7007430, GB:M25108, SP:P05106, and PID:386833; identified by sequence similarity; putative; Belongs to the CtsR family.	Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons.	0.784
hrcA	ctsR	EF_1306	EF_3283	Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons.	Transcriptional regulator CtsR; Similar to GP:7007430, GB:M25108, SP:P05106, and PID:386833; identified by sequence similarity; putative; Belongs to the CtsR family.	0.784
lexA	codY	EF_1579	EF_1645	Transcriptional repressor LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.	Transcriptional regulator CodY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; Belongs to the CodY family.	0.451
lexA	recA	EF_1579	EF_3171	Transcriptional repressor LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.	recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.	0.995
nagA-1	EF_0451	EF_1317	EF_0451	N-acetylglucosamine-6-phosphate deacetylase; Identified by match to TIGR protein family HMM TIGR00221.	Glucosamine-6-phosphate isomerase, putative; Identified by match to TIGR protein family HMM TIGR01198.	0.982
nagA-1	nagA-2	EF_1317	EF_3044	N-acetylglucosamine-6-phosphate deacetylase; Identified by match to TIGR protein family HMM TIGR00221.	N-acetylglucosamine-6-phosphate deacetylase; Identified by match to TIGR protein family HMM TIGR00221.	0.919
nagA-1	nagB	EF_1317	EF_0466	N-acetylglucosamine-6-phosphate deacetylase; Identified by match to TIGR protein family HMM TIGR00221.	Glucosamine-6-phosphate isomerase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.	0.998
nagA-2	EF_0451	EF_3044	EF_0451	N-acetylglucosamine-6-phosphate deacetylase; Identified by match to TIGR protein family HMM TIGR00221.	Glucosamine-6-phosphate isomerase, putative; Identified by match to TIGR protein family HMM TIGR01198.	0.986
nagA-2	nagA-1	EF_3044	EF_1317	N-acetylglucosamine-6-phosphate deacetylase; Identified by match to TIGR protein family HMM TIGR00221.	N-acetylglucosamine-6-phosphate deacetylase; Identified by match to TIGR protein family HMM TIGR00221.	0.919
nagA-2	nagB	EF_3044	EF_0466	N-acetylglucosamine-6-phosphate deacetylase; Identified by match to TIGR protein family HMM TIGR00221.	Glucosamine-6-phosphate isomerase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.	0.998
nagA-2	pyraA	EF_3044	EF_1717	N-acetylglucosamine-6-phosphate deacetylase; Identified by match to TIGR protein family HMM TIGR00221.	Carbamoyl-phosphate synthase, small subunit; Similar to GP:7688228, and SP:P25993; identified by sequence similarity; putative; Belongs to the CarA family.	0.454
nagB	nagA-1	EF_0466	EF_1317	Glucosamine-6-phosphate isomerase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.	N-acetylglucosamine-6-phosphate deacetylase; Identified by match to TIGR protein family HMM TIGR00221.	0.998
nagB	nagA-2	EF_0466	EF_3044	Glucosamine-6-phosphate isomerase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.	N-acetylglucosamine-6-phosphate deacetylase; Identified by match to TIGR protein family HMM TIGR00221.	0.998
pyrB	pyrC	EF_1719	EF_1718	Aspartate carbamoyltransferase; Similar to SP:P05654; identified by sequence similarity; putative; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.	Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.	0.999