15 items (Enterococcus faecalis V583) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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	purA	Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (430 aa)
	EF_1037	L-aspartate beta-decarboxylase, putative; Similar to GP:14279103; identified by sequence similarity; putative. (536 aa)
	EF_1163	L-asparaginase, putative; Similar to GP:10174241; identified by sequence similarity; putative. (321 aa)
	EF_1314	Aspartate aminotransferase, putative; Similar to GB:L05611, SP:Q04729, and PID:551706; identified by sequence similarity; putative. (405 aa)
	gdhA	Glutamate dehydrogenase; Similar to GP:10174720; identified by sequence similarity; putative; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (448 aa)
	pyraB	Carbamoyl-phosphate synthase, large subunit; Similar to GP:2598551, and SP:P25994; identified by sequence similarity; putative. (1060 aa)
	pyraA	Carbamoyl-phosphate synthase, small subunit; Similar to GP:7688228, and SP:P25993; identified by sequence similarity; putative; Belongs to the CarA family. (359 aa)
	pyrB	Aspartate carbamoyltransferase; Similar to SP:P05654; identified by sequence similarity; putative; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (308 aa)
	purF	Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (479 aa)
	purQ	Phosphoribosylformylglycinamidine synthetase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] (224 aa)
	glmS	Glucosamine--fructose-6-phosphate aminotransferase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (602 aa)
	glnA	Glutamine synthetase, type I; Identified by match to PFAM protein family HMM PF03951. (446 aa)
	purB	Adenylosuccinate lyase; Similar to SP:P12047; identified by sequence similarity; putative; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (431 aa)
	aspB	Aspartate aminotransferase; Similar to GP:6465901, GB:M23442, GB:M13982, SP:P05112, PID:186337, PID:307061, PID:33832, and PID:673419; identified by sequence similarity; putative. (399 aa)
	gltA	Glutamate synthase (NADPH), homotetrameric; Similar to GB:L19221, and PID:410147; identified by sequence similarity; putative. (472 aa)

Your Current Organism:

Enterococcus faecalis V583

NCBI taxonomy Id: 226185
Other names: E. faecalis V583, Enterococcus faecalis str. V583, Enterococcus faecalis strain V583

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EF_1037	EF_1163	EF_1037	EF_1163	L-aspartate beta-decarboxylase, putative; Similar to GP:14279103; identified by sequence similarity; putative.	L-asparaginase, putative; Similar to GP:10174241; identified by sequence similarity; putative.	0.911
EF_1037	EF_1314	EF_1037	EF_1314	L-aspartate beta-decarboxylase, putative; Similar to GP:14279103; identified by sequence similarity; putative.	Aspartate aminotransferase, putative; Similar to GB:L05611, SP:Q04729, and PID:551706; identified by sequence similarity; putative.	0.903
EF_1037	purA	EF_1037	EF_0014	L-aspartate beta-decarboxylase, putative; Similar to GP:14279103; identified by sequence similarity; putative.	Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.	0.914
EF_1037	pyrB	EF_1037	EF_1719	L-aspartate beta-decarboxylase, putative; Similar to GP:14279103; identified by sequence similarity; putative.	Aspartate carbamoyltransferase; Similar to SP:P05654; identified by sequence similarity; putative; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.	0.907
EF_1163	EF_1037	EF_1163	EF_1037	L-asparaginase, putative; Similar to GP:10174241; identified by sequence similarity; putative.	L-aspartate beta-decarboxylase, putative; Similar to GP:14279103; identified by sequence similarity; putative.	0.911
EF_1163	aspB	EF_1163	EF_2372	L-asparaginase, putative; Similar to GP:10174241; identified by sequence similarity; putative.	Aspartate aminotransferase; Similar to GP:6465901, GB:M23442, GB:M13982, SP:P05112, PID:186337, PID:307061, PID:33832, and PID:673419; identified by sequence similarity; putative.	0.911
EF_1163	purA	EF_1163	EF_0014	L-asparaginase, putative; Similar to GP:10174241; identified by sequence similarity; putative.	Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.	0.911
EF_1163	pyrB	EF_1163	EF_1719	L-asparaginase, putative; Similar to GP:10174241; identified by sequence similarity; putative.	Aspartate carbamoyltransferase; Similar to SP:P05654; identified by sequence similarity; putative; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.	0.905
EF_1314	EF_1037	EF_1314	EF_1037	Aspartate aminotransferase, putative; Similar to GB:L05611, SP:Q04729, and PID:551706; identified by sequence similarity; putative.	L-aspartate beta-decarboxylase, putative; Similar to GP:14279103; identified by sequence similarity; putative.	0.903
EF_1314	gdhA	EF_1314	EF_1415	Aspartate aminotransferase, putative; Similar to GB:L05611, SP:Q04729, and PID:551706; identified by sequence similarity; putative.	Glutamate dehydrogenase; Similar to GP:10174720; identified by sequence similarity; putative; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	0.915
aspB	EF_1163	EF_2372	EF_1163	Aspartate aminotransferase; Similar to GP:6465901, GB:M23442, GB:M13982, SP:P05112, PID:186337, PID:307061, PID:33832, and PID:673419; identified by sequence similarity; putative.	L-asparaginase, putative; Similar to GP:10174241; identified by sequence similarity; putative.	0.911
gdhA	EF_1314	EF_1415	EF_1314	Glutamate dehydrogenase; Similar to GP:10174720; identified by sequence similarity; putative; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	Aspartate aminotransferase, putative; Similar to GB:L05611, SP:Q04729, and PID:551706; identified by sequence similarity; putative.	0.915
gdhA	glnA	EF_1415	EF_2159	Glutamate dehydrogenase; Similar to GP:10174720; identified by sequence similarity; putative; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	Glutamine synthetase, type I; Identified by match to PFAM protein family HMM PF03951.	0.937
gdhA	gltA	EF_1415	EF_2560	Glutamate dehydrogenase; Similar to GP:10174720; identified by sequence similarity; putative; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	Glutamate synthase (NADPH), homotetrameric; Similar to GB:L19221, and PID:410147; identified by sequence similarity; putative.	0.958
gdhA	purQ	EF_1415	EF_1783	Glutamate dehydrogenase; Similar to GP:10174720; identified by sequence similarity; putative; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	Phosphoribosylformylglycinamidine synthetase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...]	0.907
glmS	glnA	EF_2151	EF_2159	Glucosamine--fructose-6-phosphate aminotransferase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.	Glutamine synthetase, type I; Identified by match to PFAM protein family HMM PF03951.	0.961
glmS	gltA	EF_2151	EF_2560	Glucosamine--fructose-6-phosphate aminotransferase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.	Glutamate synthase (NADPH), homotetrameric; Similar to GB:L19221, and PID:410147; identified by sequence similarity; putative.	0.911
glmS	purA	EF_2151	EF_0014	Glucosamine--fructose-6-phosphate aminotransferase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.	Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.	0.496
glmS	purF	EF_2151	EF_1781	Glucosamine--fructose-6-phosphate aminotransferase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.	Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.	0.918
glmS	purQ	EF_2151	EF_1783	Glucosamine--fructose-6-phosphate aminotransferase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.	Phosphoribosylformylglycinamidine synthetase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...]	0.920