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YOR128C YOR128C YHR202W YHR202W YEL021W YEL021W YJR105W YJR105W IMD IMD YER170W YER170W YGR209C YGR209C YML056C YML056C YPL156C YPL156C YEL042W YEL042W YJR069C YJR069C YJR057W YJR057W YBL039C YBL039C YER070W YER070W YKL067W YKL067W YER062C YER062C YDL010W YDL010W YCL035C YCL035C YBR252W YBR252W YNL220W YNL220W YBR014C YBR014C YMR120C YMR120C YKL216W YKL216W YHR128W YHR128W YAR015W YAR015W YBR284W YBR284W YBR111C YBR111C YNL141W YNL141W YCR083W YCR083W YLR028C YLR028C YML022W YML022W YDR441C YDR441C YGL016W YGL016W YLR245C YLR245C YDR454C YDR454C YDR513W YDR513W YDR226W YDR226W YDL238C YDL238C YHR043C YHR043C YMR271C YMR271C YLR209C YLR209C YJR103W YJR103W YPL091W YPL091W YIL066C YIL066C YJL026W YJL026W YGR180C YGR180C YKL033W-A YKL033W-A YHR144C YHR144C YKL024C YKL024C IMD-2 IMD-2 YML035C YML035C YHR216W YHR216W YML106W YML106W YLR043C YLR043C
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
YOR128CPhosphoribosylaminoimidazole carboxylase; In the C-terminal section; belongs to the AIR carboxylase family. Class I subfamily. (571 aa)
YHR202WYHR202W-like protein. (601 aa)
YEL021WOrotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. (267 aa)
YJR105WADO1-like protein. (340 aa)
IMDInosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (523 aa)
YER170WGTP:AMP phosphotransferase, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. (235 aa)
YGR209CThioredoxin; Belongs to the thioredoxin family. (104 aa)
YML056CIMD4-like protein. (340 aa)
YPL156CPRM4-like protein. (287 aa)
YEL042WGDA1-like protein; Belongs to the GDA1/CD39 NTPase family. (517 aa)
YJR069CInosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and 5-bromodeoxyuridine 5'-triphosphate (BrdUTP) to their respective monophosphate derivatives. Xanthosine 5'-triphosphate (XTP) is also a potential substrate. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and [...] (197 aa)
YJR057WCDC8-like protein. (253 aa)
YBL039CCTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (579 aa)
YER070WRNR1-like protein. (130 aa)
YKL067WNucleoside diphosphate kinase. (153 aa)
YER062CHOR2-like protein. (250 aa)
YDL010WGRX6-like protein. (232 aa)
YCL035CGRX1-like protein. (110 aa)
YBR252WDUT1-like protein. (147 aa)
YNL220WAdenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (433 aa)
YBR014CGRX7-like protein. (204 aa)
YMR120CADE17-like protein. (592 aa)
YKL216WURA1-like protein. (410 aa)
YHR128WFUR1-like protein. (216 aa)
YAR015WADE1-like protein. (306 aa)
YBR284WYBR284W-like protein. (797 aa)
YBR111CYSA1-like protein. (235 aa)
YNL141WAdenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily. (347 aa)
YCR083WThioredoxin; Belongs to the thioredoxin family. (120 aa)
YLR028CADE16-like protein. (591 aa)
YML022WAPT1-like protein. (187 aa)
YDR441CAPT2-like protein. (171 aa)
YGL016WKAP122-like protein. (1081 aa)
YLR245CCytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (142 aa)
YDR454CGUK1-like protein. (187 aa)
YDR513WGRX2-like protein. (145 aa)
YDR226WAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. (261 aa)
YDL238CGUD1-like protein. (142 aa)
YHR043CDOG2-like protein. (246 aa)
YMR271CURA10-like protein. (227 aa)
YLR209CPurine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (311 aa)
YJR103WCTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (580 aa)
YPL091WGlutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (483 aa)
YIL066CRibonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (866 aa)
YJL026WRNR2-like protein. (367 aa)
YGR180CRNR4-like protein. (345 aa)
YKL033W-AYKL033W-A-like protein. (236 aa)
YHR144CDCD1-like protein. (315 aa)
YKL024CUridylate kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and dUMP as phosphate acceptors, but can also use CMP, dCMP and AMP. Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. (204 aa)
IMD-2Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (523 aa)
YML035CAMD1-like protein; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (810 aa)
YHR216WInosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (523 aa)
YML106WURA5-like protein. (226 aa)
YLR043CThioredoxin; Belongs to the thioredoxin family. (103 aa)
Your Current Organism:
Saccharomyces kudriavzevii
NCBI taxonomy Id: 226230
Other names: S. kudriavzevii IFO 1802, Saccharomyces kudriavzevii IFO 1802
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