26 items (Aspergillus nidulans) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ANIA_09149	Membrane bound C2 domain protein (Vp115), putative (AFU_orthologue AFUA_7G01840). (1506 aa)
	sey1	Protein sey1; Cooperates with the reticulon proteins and tubule-shaping DP1 family proteins to generate and maintain the structure of the tubular endoplasmic reticulum network. Has GTPase activity, which is required for its function in ER organization; Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3-type GTPase family. RHD3 subfamily. (858 aa)
	ANIA_01526	ER membrane protein complex subunit 3; The EMC seems to be required for efficient folding of proteins in the endoplasmic reticulum (ER). Belongs to the EMC3 family. (266 aa)
	yop1	Protein yop1; Involved in membrane/vesicle trafficking; Belongs to the DP1 family. (169 aa)
	ANIA_02477	Plasma membrane channel protein (Aqy1), putative (AFU_orthologue AFUA_4G02970). (841 aa)
	get3	ATPase get3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...] (340 aa)
	ANIA_03190	Zinc_ribbon_10 domain-containing protein. (399 aa)
	ANIA_04181	Uncharacterized protein. (508 aa)
	ANIA_04249	Uncharacterized protein. (311 aa)
	get1	Protein get1; Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Acts as a membrane receptor for soluble get3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. (197 aa)
	ANIA_04406	Integral ER membrane protein Scs2, putative (AFU_orthologue AFUA_4G06950). (263 aa)
	ANIA_04971	C6 transcription factor, putative (AFU_orthologue AFUA_3G10160). (1167 aa)
	ANIA_05624	C2 domain protein (AFU_orthologue AFUA_4G11110). (1237 aa)
	ANIA_05625	Uncharacterized protein. (291 aa)
	sec31	Protein transport protein sec31; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity). (1282 aa)
	ANIA_06307	Lectin family integral membrane protein, putative (AFU_orthologue AFUA_2G12180). (360 aa)
	ANIA_06515	DUF410 domain protein (AFU_orthologue AFUA_6G05050). (345 aa)
	ANIA_08501	C6 finger domain protein, putative (AFU_orthologue AFUA_1G01560). (599 aa)
	ANIA_01002	Exocyst complex component SEC5; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family. (1035 aa)
	rgsC	Intermediate filament, regulator of G-protein signaling (Eurofung). (1224 aa)
	ANIA_01382	Uncharacterized protein. (442 aa)
	ANIA_10851	Uncharacterized protein. (192 aa)
	ANIA_06059	Protein YOP1. (320 aa)
	ANIA_07341	Uncharacterized protein. (334 aa)
	ANIA_07165	Plasma membrane stress response protein (Ist2), putative (AFU_orthologue AFUA_4G03330). (715 aa)
	ANIA_05404	Reticulon-like protein. (326 aa)

Your Current Organism:

Aspergillus nidulans

NCBI taxonomy Id: 227321
Other names: A. nidulans FGSC A4, Aspergillus nidulans FGSC A4, Emericella nidulans FGSC A4

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANIA_01382	ANIA_04406	C8VRU4	Q5B4X4	Uncharacterized protein.	Integral ER membrane protein Scs2, putative (AFU_orthologue AFUA_4G06950).	0.439
ANIA_01382	ANIA_09149	C8VRU4	C8VK49	Uncharacterized protein.	Membrane bound C2 domain protein (Vp115), putative (AFU_orthologue AFUA_7G01840).	0.442
ANIA_01526	ANIA_04406	Q5BD54	Q5B4X4	ER membrane protein complex subunit 3; The EMC seems to be required for efficient folding of proteins in the endoplasmic reticulum (ER). Belongs to the EMC3 family.	Integral ER membrane protein Scs2, putative (AFU_orthologue AFUA_4G06950).	0.440
ANIA_01526	get1	Q5BD54	Q5B538	ER membrane protein complex subunit 3; The EMC seems to be required for efficient folding of proteins in the endoplasmic reticulum (ER). Belongs to the EMC3 family.	Protein get1; Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Acts as a membrane receptor for soluble get3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.	0.552
ANIA_01526	get3	Q5BD54	Q5B971	ER membrane protein complex subunit 3; The EMC seems to be required for efficient folding of proteins in the endoplasmic reticulum (ER). Belongs to the EMC3 family.	ATPase get3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...]	0.498
ANIA_03190	ANIA_05404	Q5B8E0	C8VGL9	Zinc_ribbon_10 domain-containing protein.	Reticulon-like protein.	0.630
ANIA_03190	ANIA_06059	Q5B8E0	C8V2U3	Zinc_ribbon_10 domain-containing protein.	Protein YOP1.	0.508
ANIA_03190	sey1	Q5B8E0	Q5BEE5	Zinc_ribbon_10 domain-containing protein.	Protein sey1; Cooperates with the reticulon proteins and tubule-shaping DP1 family proteins to generate and maintain the structure of the tubular endoplasmic reticulum network. Has GTPase activity, which is required for its function in ER organization; Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3-type GTPase family. RHD3 subfamily.	0.565
ANIA_03190	yop1	Q5B8E0	Q5BB01	Zinc_ribbon_10 domain-containing protein.	Protein yop1; Involved in membrane/vesicle trafficking; Belongs to the DP1 family.	0.495
ANIA_04181	get1	Q5B5J9	Q5B538	Uncharacterized protein.	Protein get1; Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Acts as a membrane receptor for soluble get3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.	0.774
ANIA_04181	get3	Q5B5J9	Q5B971	Uncharacterized protein.	ATPase get3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...]	0.792
ANIA_04249	get1	Q5B5D1	Q5B538	Uncharacterized protein.	Protein get1; Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Acts as a membrane receptor for soluble get3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.	0.481
ANIA_04406	ANIA_01382	Q5B4X4	C8VRU4	Integral ER membrane protein Scs2, putative (AFU_orthologue AFUA_4G06950).	Uncharacterized protein.	0.439
ANIA_04406	ANIA_01526	Q5B4X4	Q5BD54	Integral ER membrane protein Scs2, putative (AFU_orthologue AFUA_4G06950).	ER membrane protein complex subunit 3; The EMC seems to be required for efficient folding of proteins in the endoplasmic reticulum (ER). Belongs to the EMC3 family.	0.440
ANIA_04406	ANIA_05404	Q5B4X4	C8VGL9	Integral ER membrane protein Scs2, putative (AFU_orthologue AFUA_4G06950).	Reticulon-like protein.	0.584
ANIA_04406	ANIA_09149	Q5B4X4	C8VK49	Integral ER membrane protein Scs2, putative (AFU_orthologue AFUA_4G06950).	Membrane bound C2 domain protein (Vp115), putative (AFU_orthologue AFUA_7G01840).	0.543
ANIA_04971	ANIA_05404	Q5B3A9	C8VGL9	C6 transcription factor, putative (AFU_orthologue AFUA_3G10160).	Reticulon-like protein.	0.407
ANIA_05404	ANIA_03190	C8VGL9	Q5B8E0	Reticulon-like protein.	Zinc_ribbon_10 domain-containing protein.	0.630
ANIA_05404	ANIA_04406	C8VGL9	Q5B4X4	Reticulon-like protein.	Integral ER membrane protein Scs2, putative (AFU_orthologue AFUA_4G06950).	0.584
ANIA_05404	ANIA_04971	C8VGL9	Q5B3A9	Reticulon-like protein.	C6 transcription factor, putative (AFU_orthologue AFUA_3G10160).	0.407