STRINGSTRING
ANIA_00913 ANIA_00913 ANIA_06496 ANIA_06496 ANIA_10701 ANIA_10701 ANIA_02261 ANIA_02261 ANIA_09407 ANIA_09407 npgA npgA stcJ stcJ ANIA_09245 ANIA_09245 atnF atnF mcd4 mcd4 ANIA_07043 ANIA_07043 ANIA_06589 ANIA_06589 ANIA_05888 ANIA_05888 ANIA_05564 ANIA_05564 ANIA_04778 ANIA_04778 ANIA_04549 ANIA_04549 fasA fasA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ANIA_00913CDP-diacylglycerol-inositol 3-phosphatidyltransferase PIS (AFU_orthologue AFUA_1G15790); Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (306 aa)
ANIA_06496Transferase (Gpi7), putative (AFU_orthologue AFUA_6G05260). (847 aa)
ANIA_10701CDP-diacylglycerol--serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (231 aa)
ANIA_02261CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin; Belongs to the CDP-alcohol phosphatidyltransferase class-II family. (534 aa)
ANIA_09407Fatty acid synthase, alpha subunit; Belongs to the thiolase-like superfamily. Fungal fatty acid synthetase subunit alpha family. (1860 aa)
npgA4'-phosphopantetheinyl transferase NpgA; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of an acyl-carrier-protein. The enzyme is able to transfer the cofactor to a broad range of enzymes with acyl- or peptidyl-carrier protein domains. Required for primary biological processes such as growth and asexual/sexual development, and activates target enzymes involved in the synthesis of metabolites such as fatty acids, polyketides and nonribosomal peptides, lysine, sideropore, penicillin, sterigmatocystin, shamixantone, dehydroaustinol, and pigments. (344 aa)
stcJSterigmatocystin biosynthesis fatty acid synthase subunit alpha; Required for the synthesis of sterigmatocystin, a polyketide, but not for primary fatty acid metabolism. Involved in the synthesis of a six-carbon fatty acid that serves to initiate the polyketide synthesis. (1559 aa)
ANIA_09245Fatty acid synthase, putative (JCVI). (538 aa)
atnF3-oxoacyl-[acyl-carrier-protein] reductase; Fatty acid synthase subunit alpha; part of the gene cluster that mediates the biosynthesis of aspercryptins, linear lipopeptides built from six amino acids including 2 highly unusual and nonproteogenic amino acids, 2-amino-octanoic acid (2aoa) and 2-amino- dodecanol (2adol). The core structure of aspercryptins is as follows: Ser/Ala-Thr-Ile/Val- 2aoa-Asn-2adol. The first step of aspercryptin biosynthesis is the generation of the fatty acid precursors, octanoic and dodecanoic acids, by the FAS subunits atnF and atnM. The fatty acid precursors [...] (1659 aa)
mcd4GPI ethanolamine phosphate transferase 1; Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor (By similarity). (930 aa)
ANIA_07043Phosphopantetheinyl transferase B. (193 aa)
ANIA_06589Phosphoethanolamine N-methyltransferase, putative (AFU_orthologue AFUA_6G04290). (1067 aa)
ANIA_05888UDP-N-acetyl-glucosamine-1-P transferase Alg7, putative (AFU_orthologue AFUA_2G11240). (408 aa)
ANIA_05564Hypothetical HAD-superfamily hydrolase (Eurofung). (483 aa)
ANIA_04778Aminoalcoholphosphotransferase (AFU_orthologue AFUA_3G06650); Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (412 aa)
ANIA_04549HAD superfamily hydrolase, putative (AFU_orthologue AFUA_2G02580). (407 aa)
fasA3-oxoacyl-[acyl-carrier-protein] reductase; Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. The alpha subunit contains domains for: acyl carrier protein, 3-oxoacyl-[acyl-carrier- protein] reductase, and 3-oxoacyl-[acyl-carrier-protein] synthase (By similarity). (1771 aa)
Your Current Organism:
Aspergillus nidulans
NCBI taxonomy Id: 227321
Other names: A. nidulans FGSC A4, Aspergillus nidulans FGSC A4, Emericella nidulans FGSC A4
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.