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| | mdm34 | Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. Mdm34 is required for the interaction of the ER-resident membrane protein mmm1 and the outer mitochondrial membrane-resident beta-barrel protein mdm10. (561 aa) |
| | ANIA_10828 | TOM complex component Tom7, putative (AFU_orthologue AFUA_6G05174). (53 aa) |
| | ANIA_06255 | Cytochrome c oxidase subunit; This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport. (84 aa) |
| | ANIA_10849 | AvaB protein. (1124 aa) |
| | ANIA_06127 | V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (151 aa) |
| | ANIA_06898 | SNF7 family protein (AFU_orthologue AFUA_5G13410). (226 aa) |
| | ANIA_06911 | Probable vacuolar protein sorting-associated protein 16 homolog; Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology. (829 aa) |
| | ANIA_06034 | Uncharacterized protein. (200 aa) |
| | ANIA_06033 | ARF GTPase activator (Glo3), putative (Eurofung). (496 aa) |
| | ANIA_05972 | Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (853 aa) |
| | ANIA_05969 | Uncharacterized protein. (91 aa) |
| | ANIA_05950 | AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (717 aa) |
| | ANIA_08291 | AP-3 complex subunit delta; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane. (934 aa) |
| | ANIA_10529 | Aminotran_1_2 domain-containing protein. (580 aa) |
| | ANIA_04031 | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST2; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...] (170 aa) |
| | ANIA_08021 | Uncharacterized protein. (413 aa) |
| | ANIA_09460 | Microsomal signal peptidase subunit (Gp23), putative (AFU_orthologue AFUA_5G03220). (247 aa) |
| | ANIA_10439 | GPI transamidase component (GAA1), putative (AFU_orthologue AFUA_6G12760). (631 aa) |
| | ANIA_11444 | Mitochondrial F1F0 ATP synthase subunit Atp18, putative (AFU_orthologue AFUA_2G02275). (58 aa) |
| | ANIA_10626 | ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (561 aa) |
| | ANIA_05083 | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (782 aa) |
| | ANIA_04547 | Coatomer subunit gamma; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (917 aa) |
| | ANIA_10611 | N-acetylglucosaminyl transferase component Gpi1 (AFU_orthologue AFUA_3G09860). (665 aa) |
| | ANIA_10553 | Cytochrome c subunit, putative (AFU_orthologue AFUA_4G07150). (152 aa) |
| | ANIA_04395 | N-glycosyl-transferase (AFU_orthologue AFUA_4G06870). (410 aa) |
| | ANIA_04388 | Cytochrome b-c1 complex subunit 7; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain; Belongs to the UQCRB/QCR7 family. (124 aa) |
| | ANIA_04297 | NADH-ubiquinone oxidoreductase subunit B, putative (AFU_orthologue AFUA_4G05860); Belongs to the complex I 20 kDa subunit family. (228 aa) |
| | ANIA_11137 | Uncharacterized protein. (51 aa) |
| | ANIA_11133 | Microsomal signal peptidase Spc12, putative (AFU_orthologue AFUA_5G05800). (91 aa) |
| | ANIA_08795 | MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family. (446 aa) |
| | ANIA_11119 | Uncharacterized protein. (399 aa) |
| | ANIA_11232 | Phosphatidylinositol:UDP-GlcNAc transferase PIG-C (AFU_orthologue AFUA_3G07170). (505 aa) |
| | ANIA_10585 | Cytochrome c oxidase subunit VIa, putative (AFU_orthologue AFUA_3G06190); Belongs to the cytochrome c oxidase subunit 6A family. (134 aa) |
| | ANIA_11543 | Uncharacterized protein. (75 aa) |
| | ANIA_07037 | Vacuolar protein sorting protein (Vps36), putative (AFU_orthologue AFUA_4G04100). (621 aa) |
| | ANIA_11565 | Mitochondrial F1F0 ATP synthase subunit F (Atp17), putative (AFU_orthologue AFUA_2G05510). (101 aa) |
| | ANIA_10987 | TPR_REGION domain-containing protein. (217 aa) |
| | ANIA_07682 | AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (156 aa) |
| | ANIA_10873 | Mitochondrial outer membrane protein (Sam50), putative (AFU_orthologue AFUA_4G04620). (516 aa) |
| | ANIA_10877 | Ubiquitin fusion degradation protein (Ufd1), putative (AFU_orthologue AFUA_4G04640). (756 aa) |
| | cyn1 | Cyanate hydratase; Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide; Belongs to the cyanase family. (160 aa) |
| | ANIA_07123 | Uncharacterized protein. (738 aa) |
| | ANIA_10639 | GPI transamidase component PIG-S, putative (AFU_orthologue AFUA_6G07180). (565 aa) |
| | ANIA_05152 | Export control protein CHS7-like, putative (AFU_orthologue AFUA_1G07110). (299 aa) |
| | ANIA_05703 | Uncharacterized protein. (224 aa) |
| | ANIA_11487 | Uncharacterized protein. (86 aa) |
| | ANIA_05588 | Intermembrane space AAA protease IAP-1 (AFU_orthologue AFUA_4G11530). (784 aa) |
| | ANIA_10682 | annotation not available (918 aa) |
| | ANIA_03467 | Uncharacterized protein; Belongs to the complex I LYR family. (100 aa) |
| | ANIA_11251 | Oxidored_q6 domain-containing protein; Belongs to the complex I 20 kDa subunit family. (211 aa) |
| | ANIA_03088 | V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (161 aa) |
| | ANIA_03087 | Uncharacterized protein. (581 aa) |
| | ANIA_03080 | Vesicle coat complex COPII, subunit Sec24 family protein, putative (Eurofung). (1031 aa) |
| | ANIA_03026 | Coatomer subunit alpha; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. (1205 aa) |
| | ANIA_10363 | DUF1746 domain-containing protein. (344 aa) |
| | ANIA_02916 | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (647 aa) |
| | ANIA_09107 | V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (99 aa) |
| | ANIA_01933 | Evolutionarily conserved protein with similarity to Orm2p (Eurofung). (349 aa) |
| | ANIA_01973 | Putative vesicle transport v-SNARE protein vti1 (Eurofung). (224 aa) |
| | ANIA_10241 | Conserved membrane protein, putative (AFU_orthologue AFUA_4G10700). (333 aa) |
| | ANIA_10250 | MCU domain-containing protein. (507 aa) |
| | tlgB | SNARE complex subunit (Tlg2), putative (Eurofung); Belongs to the syntaxin family. (386 aa) |
| | ANIA_08890 | Cellobiose dehydrogenase, putative (AFU_orthologue AFUA_8G05805). (401 aa) |
| | ANIA_10265 | Mannan polymerase II complex ANP1 subunit Anp1, putative (AFU_orthologue AFUA_2G15910). (499 aa) |
| | ANIA_11303 | Uncharacterized protein. (92 aa) |
| | ANIA_01455 | Uncharacterized protein. (741 aa) |
| | ANIA_01523 | ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (556 aa) |
| | ANIA_02260 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (136 aa) |
| | ANIA_02306 | Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (228 aa) |
| | ANIA_02315 | ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (518 aa) |
| | ANIA_02414 | Complex1_49kDa domain-containing protein; Belongs to the complex I 49 kDa subunit family. (475 aa) |
| | ANIA_10229 | NADH-ubiquinone oxidoreductase 30.4 kDa subunit, mitochondrial [Precursor] (Eurofung); Belongs to the complex I 30 kDa subunit family. (290 aa) |
| | ANIA_10305 | Vacuolar ATP synthase 16 kDa proteolipid subunit, putative (AFU_orthologue AFUA_3G12370); Belongs to the V-ATPase proteolipid subunit family. (151 aa) |
| | ANIA_00165 | AP-3 adaptor complex subunit beta, putative (AFU_orthologue AFUA_5G11360). (841 aa) |
| | ANIA_00162 | Putative APSES transcription factor (Eurofung). (424 aa) |
| | ANIA_00110 | Vacuolar ATP synthase subunit D, putative (AFU_orthologue AFUA_5G11920). (216 aa) |
| | ANIA_00665 | Coatomer subunit epsilon; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. Belongs to the COPE family. (315 aa) |
| | ANIA_01365 | SNF7 family protein (AFU_orthologue AFUA_1G09220). (208 aa) |
| | ANIA_11278 | MICOS complex subunit MIC10; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (91 aa) |
| | ANIA_00650 | Uncharacterized protein. (723 aa) |
| | ANIA_01281 | Mitochondrial import inner membrane translocase subunit TIM44; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the Tim44 family. (514 aa) |
| | ANIA_01195 | V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (390 aa) |
| | ANIA_10078 | Peroxisomal fatty acid ABC transporter, putative (Eurofung). (820 aa) |
| | pam17 | Presequence translocated-associated motor subunit pam17, mitochondrial; Component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. (252 aa) |
| | ANIA_11267 | Uncharacterized protein. (93 aa) |
| | ANIA_10032 | ATP synthase delta chain, mitochondrial, putative (AFU_orthologue AFUA_1G03100). (166 aa) |
| | ANIA_10047 | Uncharacterized protein. (472 aa) |
| | ANIA_10129 | Vacuolar protein sorting-associated protein 28; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. (244 aa) |
| | ANIA_00252 | ATP synthase subunit gamma. (296 aa) |
| | ANIA_00235 | Serine-threonine kinase and endoribonuclease (Eurofung). (1121 aa) |
| | ANIA_00896 | Succinate dehydrogenase [ubiquinone] cytochrome b small subunit. (167 aa) |
| | digA | Pep3_Vps18 domain-containing protein. (963 aa) |
| | ganB | Uncharacterized protein. (356 aa) |
| | ANIA_02418 | Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (655 aa) |
| | ANIA_03729 | FKS1_dom1 domain-containing protein. (1905 aa) |
| | ANID_20010 | ATP synthase subunit a. (256 aa) |
| | ANID_20014 | Cytochrome c oxidase subunit 1; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. (580 aa) |
| | ANID_20017 | ATP synthase subunit 9, mitochondrial; Belongs to the ATPase C chain family. (74 aa) |
| | atp8 | ATP synthase protein 8; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subuni [...] (48 aa) |
| | atp9 | ATP synthase subunit 9, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the centr [...] (143 aa) |
| | palA | pH-response regulator protein palA/RIM20; Required for the proteolytic cleavage of the transcription factor pacC in response to alkaline ambient pH. May act as a scaffold protein that recruits the calpain-like protease palB via vps32 to its substrate pacC (By similarity); Belongs to the palA/RIM20 family. (847 aa) |
| | palB | Calpain-like protease palB; Required for the proteolytic cleavage of the transcription factor pacC in response to alkaline ambient pH. Probably is the signaling protease that mediates the first proteolytic cleavage within the signaling protease box of pacC, yielding the 53 kDa 'open' conformation intermediate protein, which is committed to further processing. Required for virulence in invasive pulmonary aspergillosis (IPA). (847 aa) |
| | fadA | Guanine nucleotide-binding protein subunit alpha; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems; Belongs to the G-alpha family. G(q) subfamily. (353 aa) |
| | mmm1 | Maintenance of mitochondrial morphology protein 1; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. The mdm12-mmm1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta- barrel proteins, and acts in a late step after the SAM complex. The mdm10-mdm12-mmm1 su [...] (472 aa) |
| | ANIA_09526 | Putative ER-Golgi SNARE complex subunit Sed5 (Eurofung). (344 aa) |
| | ANIA_09444 | CFEM domain-containing protein. (406 aa) |
| | ANIA_09396 | SNF7 family protein Fti1/Did2, putative (AFU_orthologue AFUA_3G04060). (209 aa) |
| | ANIA_09089 | Uncharacterized protein. (565 aa) |
| | ANIA_09078 | Uncharacterized protein. (152 aa) |
| | ANIA_09037 | Periplasmic nitrate reductase, putative (AFU_orthologue AFUA_3G15190). (1009 aa) |
| | ANIA_09036 | Uncharacterized protein. (401 aa) |
| | ANIA_08986 | Uncharacterized protein. (417 aa) |
| | ANIA_08793 | Uncharacterized protein. (191 aa) |
| | ANIA_08769 | Putative synaptobrevin homologue SNC1/2 (Eurofung). (117 aa) |
| | ANIA_08763 | NADH-ubiquinone oxidoreductase 105 kDa subunit (AFU_orthologue AFUA_6G02960). (94 aa) |
| | ANIA_08607 | Uncharacterized protein. (206 aa) |
| | ANIA_08258 | Ubiquitin conjugating enzyme (UbcH), putative (AFU_orthologue AFUA_5G04060); Belongs to the ubiquitin-conjugating enzyme family. (166 aa) |
| | ANIA_08179 | DnaJ domain protein (AFU_orthologue AFUA_5G03040). (748 aa) |
| | ANIA_08166 | Uncharacterized protein. (449 aa) |
| | ANIA_08118 | Cytochrome c oxidase subunit Va, putative (AFU_orthologue AFUA_5G02750). (157 aa) |
| | ANIA_08059 | Mitochondrial import inner membrane translocase subunit TIM22. (181 aa) |
| | lbsA | Lactobacillus shifted protein. (213 aa) |
| | ANIA_08022 | Uncharacterized protein. (71 aa) |
| | ANIA_07741 | AP-2 adaptor complex subunit mu, putative (AFU_orthologue AFUA_5G07930); Belongs to the adaptor complexes medium subunit family. (454 aa) |
| | ANIA_07736 | C2H2 finger and ankyrin domain protein, putative (AFU_orthologue AFUA_5G07960). (637 aa) |
| | ANIA_07721 | Plug_translocon domain-containing protein. (478 aa) |
| | ANIA_07672 | Alpha-1,6 mannosyltransferase subunit (Mnn9), putative (AFU_orthologue AFUA_2G01450). (379 aa) |
| | ANIA_07629 | NADH-ubiquinone oxidoreductase B12 subunit, putative (AFU_orthologue AFUA_5G07380). (84 aa) |
| | ANIA_07603 | V-ATPase proteolipid subunit Ppa1, putative (AFU_orthologue AFUA_2G15560); Belongs to the V-ATPase proteolipid subunit family. (200 aa) |
| | ANIA_07497 | NADH-ubiquinone oxidoreductase 18 kDa subunit, putative (AFU_orthologue AFUA_2G05500). (221 aa) |
| | ANIA_07472 | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...] (502 aa) |
| | ANIA_07426 | Oligosaccharyl transferase subunit (Gamma), putative (AFU_orthologue AFUA_2G06280). (127 aa) |
| | ANIA_07395 | Integral membrane protein (AFU_orthologue AFUA_5G00840). (357 aa) |
| | ANIA_07314 | Polyphosphoinositide phosphatase Fig4 (AFU_orthologue AFUA_2G16640). (1013 aa) |
| | ANIA_07310 | Vacuolar sorting protein SNF7 family protein, putative (AFU_orthologue AFUA_2G16692). (473 aa) |
| | cdc48 | Cell division control protein 48; Involved in spindle disassembly, degradation of ubiquitinated proteins and protein export from the endoplasmic reticulum to the cytoplasm. Acts as a chaperone that collects ubiquitinated substrates. Has a role in the endoplasmic reticulum-associated degradation (ERAD) pathway. Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation. Cdc48 may provide the mechanical force that dislodges the polyubiquitinated n [...] (823 aa) |
| | ANIA_07106 | Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family. (264 aa) |
| | ANIA_07016 | AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (935 aa) |
| | ANIA_06976 | NADH-ubiquinone oxidoreductase 21 kDa subunit, putative (AFU_orthologue AFUA_4G04750). (189 aa) |
| | ANIA_06941 | Integral membrane protein (AFU_orthologue AFUA_3G03520). (405 aa) |
| | ANIA_06920 | SNF7 family protein (AFU_orthologue AFUA_5G13890). (228 aa) |
| | ANIA_06841 | Mitochondrial inner membrane protease subunit 1, putative (AFU_orthologue AFUA_5G12820). (182 aa) |
| | ANIA_06631 | ATP synthase subunit d, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the cent [...] (173 aa) |
| | ANIA_06627 | Signal sequence receptor alpha subunit, putative (AFU_orthologue AFUA_6G03850). (636 aa) |
| | ANIA_06557 | NADH-ubiquinone oxidoreductase B14 subunit, putative (AFU_orthologue AFUA_6G04620). (123 aa) |
| | ANIA_06546 | Vacuolar protein sorting 55 superfamily (AFU_orthologue AFUA_6G04780). (128 aa) |
| | ANIA_06545 | Sld7_C domain-containing protein. (446 aa) |
| | ANIA_06544 | UPF0220 domain protein (AFU_orthologue AFUA_6G04760). (174 aa) |
| | ANIA_06510 | Mitochondrial import receptor subunit (Tom40), putative (AFU_orthologue AFUA_6G05110). (355 aa) |
| | ANIA_06369 | ABC transporter, putative (Eurofung). (559 aa) |
| | ANIA_06367 | PIPK domain-containing protein. (342 aa) |
| | ANIA_06353 | Acetyltransferase, GNAT family family (AFU_orthologue AFUA_3G07750). (421 aa) |
| | ANIA_06348 | Mitochondrial import inner membrane translocase subunit TIM23. (205 aa) |
| | ANIA_06287 | ATP synthase oligomycin sensitivity conferral protein, putative (AFU_orthologue AFUA_2G12400). (227 aa) |
| | ANIA_06267 | Vesicular-fusion protein sec17 (AFU_orthologue AFUA_2G12870). (293 aa) |
| | sec31 | Protein transport protein sec31; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity). (1282 aa) |
| | ANIA_06248 | GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family. (252 aa) |
| | ANIA_06232 | Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (507 aa) |
| | ANIA_06177 | Flotillin domain protein (AFU_orthologue AFUA_2G08180); Belongs to the band 7/mec-2 family. Flotillin subfamily. (423 aa) |
| | ANIA_06132 | Uncharacterized protein. (1272 aa) |
| | ANIA_06080 | Coatomer subunit zeta; The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex. (200 aa) |
| | ANIA_06077 | NADH-ubiquinone oxidoreductase 24 kDa subunit, mitochondrial [Precursor] (Eurofung). (270 aa) |
| | ANIA_06047 | SNARE protein (Ufe1), putative (AFU_orthologue AFUA_2G09670). (332 aa) |
| | ANIA_06046 | NADPH oxidase complex regulatory component (Eurofung). (517 aa) |
| | ANIA_06028 | NAD_binding_2 domain-containing protein. (320 aa) |
| | ANIA_05971 | NADH-ubiquinone oxidoreductase 299 kDa subunit, putative (AFU_orthologue AFUA_2G10600). (239 aa) |
| | ANIA_05951 | ER membrane DUF1077 domain protein, putative (AFU_orthologue AFUA_2G10350). (255 aa) |
| | ANIA_05888 | UDP-N-acetyl-glucosamine-1-P transferase Alg7, putative (AFU_orthologue AFUA_2G11240). (408 aa) |
| | ANIA_05880 | V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (124 aa) |
| | ANIA_05857 | Phospholipid metabolism enzyme regulator, putative (AFU_orthologue AFUA_2G08080). (903 aa) |
| | ANIA_05819 | SRP receptor beta subunit (Srp102), putative (AFU_orthologue AFUA_2G07600). (317 aa) |
| | ANIA_05736 | Glycosyltransferase family protein (AFU_orthologue AFUA_6G06940). (301 aa) |
| | pam16 | Mitochondrial import inner membrane translocase subunit tim16; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. In the complex, it is required to regulate activity of mtHSP70 (SSC1/sscA) via its interaction with PAM18/TIM14. May act by positioning PAM18/pamR in juxtaposition to mtHSP70 at the translocon to maximize ATPase stimulation (By similarity); Belongs to the TIM16/PAM16 family. (135 aa) |
| | ANIA_05641 | AP-3 adaptor complex subunit mu, putative (AFU_orthologue AFUA_4G13490); Belongs to the adaptor complexes medium subunit family. (636 aa) |
| | ANIA_05629 | NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. (497 aa) |
| | ANIA_05606 | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (852 aa) |
| | ANIA_05519 | AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (185 aa) |
| | ANIA_05211 | 1-phosphatidylinositol-3-phosphate 5-kinase (Fab1), putative (AFU_orthologue AFUA_6G07440). (108 aa) |
| | ANIA_05127 | Putative ER-golgi SNARE complex subunit Bet1 (Eurofung). (168 aa) |
| | ANIA_05008 | Uncharacterized protein. (115 aa) |
| | ANIA_04951 | Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (866 aa) |
| | ANIA_04927 | Mitochondrial F1F0 ATP synthase subunit Atp14, putative (AFU_orthologue AFUA_3G10630). (124 aa) |
| | ANIA_04876 | Vacuolar assembly protein, putative (AFU_orthologue AFUA_3G11200). (1280 aa) |
| | ANIA_04795 | Ras-GEF domain-containing protein. (478 aa) |
| | ANIA_04732 | Rad60-SLD_2 domain-containing protein. (253 aa) |
| | ANIA_04728 | EMC1_C domain-containing protein. (889 aa) |
| | ANIA_04718 | V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (237 aa) |
| | ANIA_04716 | Alpha-1,6-mannosyltransferase subunit (Och1), putative (AFU_orthologue AFUA_5G08580). (362 aa) |
| | ANIA_04709 | Phosphatidylinositol 3-kinase VPS34. (897 aa) |
| | ANIA_04683 | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit WBP1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...] (460 aa) |
| | ANIA_04633 | Mitochondrial genome maintenance protein Mgr2, putative (AFU_orthologue AFUA_2G02430). (108 aa) |
| | ANIA_04589 | Protein translocation complex subunit Sss1, putative (AFU_orthologue AFUA_3G06901). (70 aa) |
| | pam18 | Mitochondrial import inner membrane translocase subunit tim14; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. In the complex, it is required to stimulate activity of mtHSP70 (SSC1/sscA) (By similarity); Belongs to the TIM14 family. (105 aa) |
| | ANIA_04557 | Mitochondrial inner membrane AAA protease Yta12, putative (AFU_orthologue AFUA_2G02680). (883 aa) |
| | ANIA_04551 | Putative SNARE complex subunit Vam7 (Eurofung). (833 aa) |
| | ANIA_04525 | Cytochrome c subunit Vb, putative (AFU_orthologue AFUA_2G03010). (194 aa) |
| | tim50 | Mitochondrial import inner membrane translocase subunit tim50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Required to direct preproteins in transit and direct them to the channel protein TIM23, and possibly facilitates transfer of the translocating proteins from the TOM complex to the TIM23 complex (By similarity). (532 aa) |
| | ANIA_04463 | Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1676 aa) |
| | ANIA_04416 | t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family. (273 aa) |
| | ANIA_04402 | Outer mitochondrial membrane protein porin (AFU_orthologue AFUA_4G06910). (284 aa) |
| | sec13 | Protein transport protein sec13; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules. It also functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport facto [...] (309 aa) |
| | ANIA_04252 | High expression lethality protein Hel10, putative (AFU_orthologue AFUA_1G06580). (189 aa) |
| | snf7 | Vacuolar-sorting protein snf7; Required for the sorting and concentration of proteins resulting in the entry of these proteins into the invaginating vesicles of the multivesicular body (MVB). (242 aa) |
| | ANIA_04207 | AP-1 complex subunit gamma. (839 aa) |
| | ANIA_04172 | Uncharacterized protein. (378 aa) |
| | gem1 | Mitochondrial Rho GTPase 1; Mitochondrial GTPase involved in mitochondrial trafficking. Probably involved in control of anterograde transport of mitochondria and their subcellular distribution. (634 aa) |
| | ANIA_04162 | TPR domain protein (AFU_orthologue AFUA_4G13160). (515 aa) |
| | ANIA_04045 | Spo7-like protein (AFU_orthologue AFUA_1G03910). (463 aa) |
| | ANIA_03922 | Uncharacterized protein. (103 aa) |
| | mic60 | MICOS complex subunit mic60; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Plays a role in keeping cristae membranes connected to the inner boundary membrane. Also promotes protein import via the mitochondrial intermembrane space assembly (MIA) pathway (By similarity). (618 aa) |
| | ANIA_03826 | GPI transamidase component PIG-U, putative (AFU_orthologue AFUA_4G08200). (407 aa) |
| | ANIA_03821 | Golgi to endosome transport protein (Ent3), putative (AFU_orthologue AFUA_2G03650). (532 aa) |
| | ANIA_03803 | Mitochondrial import receptor subunit (Tom37), putative (AFU_orthologue AFUA_2G03840). (421 aa) |
| | ANIA_03740 | Amidohydro-rel domain-containing protein. (360 aa) |
| | ANIA_03728 | Serine palmitoyl CoA transferase subunit LCBA. (504 aa) |
| | sec24 | Protein transport protein sec24; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity). (908 aa) |
| | ANIA_03642 | Vacuolar protein sorting-associated protein 26, putative (AFU_orthologue AFUA_4G12060). (347 aa) |
| | ANIA_03445 | Chitin synthase activator (Chs3), putative (AFU_orthologue AFUA_3G05580). (723 aa) |
| | ANIA_03168 | V-type proton ATPase subunit; Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. The active enzyme consists of a catalytic V1 domain attached to an integral membrane V0 proton pore complex. This subunit is a non-integral membrane component of the membrane pore domain and is required for proper assembly of the V0 sector. Might be involved in the regulated assembly of V1 subunits onto the membrane sector or alternatively may prevent the passage of protons through V0 pores; Belongs to the V-ATPase V0D/AC39 subunit family. (362 aa) |
| | ANIA_03149 | Mitochondrial inner membrane protease subunit Imp2, putative (AFU_orthologue AFUA_3G13840). (282 aa) |
| | sec11 | Signal peptidase complex catalytic subunit sec11; Catalytic component of the signal peptidase complex (SPC), which catalyzes the cleavage of N-terminal signal sequences of proteins targeted to the endoplasmic reticulum. Signal peptide cleavage occurs during the translocation (cotranslationally or post-translationally) through the translocon pore into the endoplasmic reticulum (By similarity). (192 aa) |
| | ANIA_03090 | G protein alpha subunit homolog GanAp. (361 aa) |
| | ANIA_03029 | AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (766 aa) |
| | ANIA_03011 | NADH-ubiquinone oxidoreductase subunit GRIM-19, putative (AFU_orthologue AFUA_3G08770). (119 aa) |
| | gpgA | G protein gamma subunit. (95 aa) |
| | ANIA_02626 | Glycosyl transferase, putative (AFU_orthologue AFUA_8G02040). (416 aa) |
| | preB | Pheromone receptor PREB. (430 aa) |
| | ANIA_02461 | Vacuolar protein sorting protein (VPS11), putative (AFU_orthologue AFUA_6G10410). (1464 aa) |
| | ANIA_02419 | t-SNARE coiled-coil homology domain-containing protein. (429 aa) |
| | ANIA_02316 | Uncharacterized protein. (197 aa) |
| | ANIA_02262 | Low-temperature viability protein ltv1 (AFU_orthologue AFUA_5G06520). (483 aa) |
| | ANIA_02224 | Vacuolar protein sorting-associated protein 17; Plays a role in vesicular protein sorting. Belongs to the VPS17 family. (574 aa) |
| | ANIA_02169 | SNARE complex subunit (Syn8), putative (AFU_orthologue AFUA_2G15820). (270 aa) |
| | ANIA_02050 | Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (240 aa) |
| | ANIA_01892 | Mitochondrial import inner membrane translocase subunit tim-17 (Broad). (153 aa) |
| | ANIA_01775 | GPI transamidase component Gpi16, putative (AFU_orthologue AFUA_6G09020). (582 aa) |
| | ANIA_01754 | Uncharacterized protein. (159 aa) |
| | ANIA_01683 | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...] (290 aa) |
| | ANIA_01663 | Uncharacterized protein. (620 aa) |
| | ANIA_01620 | Glycosyl transferase, putative (AFU_orthologue AFUA_8G02040). (387 aa) |
| | ANIA_01535 | Uncharacterized protein. (391 aa) |
| | ANIA_01534 | ATP synthase subunit 4, mitochondrial (Broad). (242 aa) |
| | ANIA_01526 | ER membrane protein complex subunit 3; The EMC seems to be required for efficient folding of proteins in the endoplasmic reticulum (ER). Belongs to the EMC3 family. (266 aa) |
| | ANIA_01488 | RING finger protein (AFU_orthologue AFUA_8G04840). (775 aa) |
| | ANIA_01459 | Mannosyltransferase PMTI (AFU_orthologue AFUA_8G04500). (773 aa) |
| | ANIA_01442 | Translocation protein (Sec66), putative (AFU_orthologue AFUA_8G04260). (272 aa) |
| | ANIA_01347 | MICOS complex subunit MIC12; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (108 aa) |
| | ANIA_01343 | NIF domain protein (AFU_orthologue AFUA_1G09460). (515 aa) |
| | ANIA_01341 | Vacuolar protein sorting-associated protein 29; Belongs to the VPS29 family. (200 aa) |
| | ANIA_01250 | Uncharacterized protein. (622 aa) |
| | ANIA_01229 | Uncharacterized protein. (183 aa) |
| | ANIA_01211 | V-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. (479 aa) |
| | ANIA_01177 | Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (950 aa) |
| | ANIA_01168 | Calcium channel. (2110 aa) |
| | ANIA_01161 | Uncharacterized protein. (123 aa) |
| | ANIA_01105 | Mitochondrial import receptor subunit tom22 (AFU_orthologue AFUA_1G11860). (153 aa) |
| | ANIA_01102 | Serine palmitoyl transferase subunit. (672 aa) |
| | ANIA_01075 | RING finger ubiquitin ligase (Tul1), putative (AFU_orthologue AFUA_1G12080). (807 aa) |
| | ANIA_01063 | NADH-ubiquinone oxidoreductase; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (159 aa) |
| | ANIA_00943 | Mitochondrial F1F0-ATP synthase g subunit, putative (AFU_orthologue AFUA_1G16280). (196 aa) |
| | ANIA_00922 | Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (516 aa) |
| | ANIA_00871 | GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family. (397 aa) |
| | ANIA_00834 | Protein translocation complex componenet (Npl1), putative (AFU_orthologue AFUA_1G14940). (696 aa) |
| | mdm12 | Mitochondrial distribution and morphology protein 12; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. Mdm12 is required for the interaction of the ER-resident membrane protein mmm1 and the outer mitochondrial membrane-resident beta-barrel protein mdm10. The mdm12-mmm1 subcomplex functions in the major beta-barrel assembly pat [...] (436 aa) |
| | ANIA_00770 | UBX domain protein (AFU_orthologue AFUA_1G14320). (512 aa) |
| | aps2 | AP-2 complex subunit sigma; Component of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration (By similarity). (145 aa) |
| | ANIA_00672 | 6-phosphogluconate dehydrogenase family protein (AFU_orthologue AFUA_1G13320). (314 aa) |
| | ANIA_00657 | Mitochondrial outer membrane protein (Sam35), putative (AFU_orthologue AFUA_1G13180). (299 aa) |
| | ANIA_00636 | Uncharacterized protein. (488 aa) |
| | ANIA_00576 | Phosphoinositide-3-kinase, regulatory protein Vps15 (Eurofung). (1599 aa) |
| | ANIA_00559 | Mitochondrial import receptor subunit (Tom20), putative (AFU_orthologue AFUA_6G11380). (169 aa) |
| | ANIA_00417 | Translocon protein Sec61beta, putative (AFU_orthologue AFUA_1G04890). (250 aa) |
| | ANIA_00412 | Uncharacterized protein. (731 aa) |
| | sar1 | Small COPII coat GTPase sar1; Small GTPase component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules. SAR1 controls the coat assembly in a stepwise manner. Activated sar1-GTP binds to membranes first and recruits the sec23/24 complex. These sec23/24-sar1 prebudding intermediates are then collected by the Sec13/31 complex as subunits polymerize to form coated trans [...] (189 aa) |
| | ANIA_00405 | Uncharacterized protein. (143 aa) |
| | ANIA_00357 | Ubiquinol-cytochrome c reductase (Eurofung). (316 aa) |
| | ANIA_00329 | Ubiquitin fusion degradation protein Ufd1, putative (AFU_orthologue AFUA_1G02430). (393 aa) |
| | ANIA_00301 | Uncharacterized protein. (322 aa) |
| | npl4 | Nuclear protein localization protein 4; Involved in the import of nuclear-targeted proteins into the nucleus and the export of poly(A) RNA out of the nucleus. Has a role in the endoplasmic reticulum-associated degradation (ERAD) pathway (By similarity); Belongs to the NPL4 family. (652 aa) |
| | sec23 | Protein transport protein sec23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity). (771 aa) |
| | sfaD | G-protein beta subunit. (352 aa) |
| | mdmB | Mitochondrial distribution and morphology protein 10; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. mdm10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the tom40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of tom40 with the recepto [...] (427 aa) |
| | palC | pH-response regulator protein palC; Required for the proteolytic cleavage of the transcription factor pacC in response to alkaline ambient pH. (507 aa) |
| | tim10 | Mitochondrial import inner membrane translocase subunit tim10; Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta- barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (By similarity); Belongs to the small Tim family. (93 aa) |
