STRINGSTRING
ANIA_02391 ANIA_02391 cbk1 cbk1 nimA nimA nimX nimX cmkA cmkA ANIA_09302 ANIA_09302 ANIA_09050 ANIA_09050 ANIA_09024 ANIA_09024 ANIA_08836 ANIA_08836 ANIA_07678 ANIA_07678 ANIA_07537 ANIA_07537 ANIA_07321 ANIA_07321 ANIA_06508 ANIA_06508 ANIA_05529 ANIA_05529 ANIA_04936 ANIA_04936 sepH sepH ANIA_03694 ANIA_03694 ANIA_03001 ANIA_03001 ANIA_02927 ANIA_02927 bud32 bud32 ssn3 ssn3 ste20 ste20 ANIA_01789 ANIA_01789 atg1 atg1 ANIA_01485 ANIA_01485 pbsA pbsA ANIA_00144 ANIA_00144 tel1 tel1 ptkA ptkA mpkC mpkC hog1 hog1 ANIA_05815 ANIA_05815 ANIA_06044 ANIA_06044 ANIA_10869 ANIA_10869 ANIA_10448 ANIA_10448 ANIA_06975 ANIA_06975 ANIA_01867 ANIA_01867 ANIA_00106 ANIA_00106 ANIA_06363 ANIA_06363 ANIA_08261 ANIA_08261
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ANIA_02391Uncharacterized protein. (1367 aa)
cbk1Serine/threonine-protein kinase cbk1; Protein kinase that seems to play a role in the regulation of cell morphogenesis and proliferation. (902 aa)
nimAG2-specific protein kinase nimA; Protein kinase that plays an important role in mitotic regulation. Seems to be phosphorylated and thereby activated by CDC2/cyclin B during mitotic activation. It is also required for spindle formation and for nuclear envelope breakdown. (699 aa)
nimXCyclin-dependent kinase 1; Plays a key role in the control of the eukaryotic cell cycle. It is required in higher cells for entry into S-phase and mitosis (By similarity). (323 aa)
cmkACalcium/calmodulin-dependent protein kinase cmkA; Calcium/calmodulin-dependent protein kinase. Required in nuclear division cycle for progression from G2 to mitosis. Required for hyphal growth. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily. (414 aa)
ANIA_09302Protein kinase domain-containing protein. (683 aa)
ANIA_09050Putative Zn(II)2Cys6 transcription factor (Eurofung). (538 aa)
ANIA_09024Protein kinase domain-containing protein. (281 aa)
ANIA_08836Non-specific serine/threonine protein kinase. (825 aa)
ANIA_07678Pom1 kinase homologue pomA (Eurofung). (1452 aa)
ANIA_07537Protein kinase, putative (AFU_orthologue AFUA_6G09240). (629 aa)
ANIA_07321Protein kinase, putative (AFU_orthologue AFUA_2G16620). (756 aa)
ANIA_06508Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (394 aa)
ANIA_05529COTA. (588 aa)
ANIA_04936Casein kinase, putative (AFU_orthologue AFUA_8G04810). (780 aa)
sepHCytokinesis protein sepH; Required for early events during cytokinesis including localization of cytoskeletal components to the cytokinetic ring. Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC7 subfamily. (1346 aa)
ANIA_03694Uncharacterized protein. (352 aa)
ANIA_03001Protein kinase domain-containing protein (AFU_orthologue AFUA_3G08710). (394 aa)
ANIA_02927Checkpoint protein kinase, putative (AFU_orthologue AFUA_3G08100). (828 aa)
bud32EKC/KEOPS complex subunit bud32; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. BUD32 has ATPase activity in the context of the EKC/KEOPS complex and likely plays a supporting role to the catalytic subunit KAE1. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is r [...] (285 aa)
ssn3Serine/threonine-protein kinase ssn3; Component of the srb8-11 complex. The srb8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription. The srb8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator. It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex. The srb8-11 complex phosphorylates the C-terminal domain (CTD) of the largest subunit of RNA polymerase II (By similarity). (426 aa)
ste20Serine/threonine-protein kinase ste20; MAP4K component of the MAPK pathway required for the mating pheromone response and the regulation of cell polarity and cell cycle. Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. (848 aa)
ANIA_01789Protein kinase domain-containing protein. (533 aa)
atg1Serine/threonine-protein kinase atg1; Serine/threonine protein kinase involved in the cytoplasm to vacuole transport (Cvt) and found to be essential in autophagy, where it is required for the formation of autophagosomes. Involved in the clearance of protein aggregates which cannot be efficiently cleared by the proteasome. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing [...] (935 aa)
ANIA_01485Casein kinase II (Eurofung); Belongs to the protein kinase superfamily. (333 aa)
pbsAMAP kinase kinase (Eurofung). (651 aa)
ANIA_00144Serine/threonine protein kinase (Nrc-2), putative (AFU_orthologue AFUA_5G11520). (572 aa)
tel1Serine/threonine-protein kinase tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability (By similarity). (2793 aa)
ptkASerine/threonine-protein kinase bur1; Serine/threonine-protein kinase involved in transcription regulation. Phosphorylates the UBC2/RAD6 ubiquitin-conjugating enzyme (E2), leading to monoubiquitination of histone H2B and the silencing of telomeric-associated genes. Also required for histone H3 methylation. Necessary for the recovery from pheromone-induced growth arrest in the cell cycle G1 phase (By similarity). (544 aa)
mpkCMitogen-activated protein kinase mpkC; Mitogen-activated protein kinase required for growth on media where sorbitol or mannitol is the sole carbon source. (415 aa)
hog1Mitogen-activated protein kinase hog1; Mitogen-activated protein kinase involved in a signal transduction pathway that is activated by changes in the osmolarity of the extracellular environment. Controls osmotic regulation of transcription of target genes; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. HOG1 sub-subfamily. (379 aa)
ANIA_05815Putative aurora kinase (Eurofung); Belongs to the protein kinase superfamily. (391 aa)
ANIA_06044Protein kinase NPKA. (467 aa)
ANIA_10869Protein kinase domain-containing protein (AFU_orthologue AFUA_2G14650). (620 aa)
ANIA_10448TPR domain protein (AFU_orthologue AFUA_3G01710). (1488 aa)
ANIA_06975UVSB; Belongs to the PI3/PI4-kinase family. (2454 aa)
ANIA_01867Cyclin-dependent protein kinase PHOB. (313 aa)
ANIA_00106Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (1085 aa)
ANIA_06363Serine/threonine-protein kinase RIO1; Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family. (558 aa)
ANIA_08261Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (366 aa)
Your Current Organism:
Aspergillus nidulans
NCBI taxonomy Id: 227321
Other names: A. nidulans FGSC A4, Aspergillus nidulans FGSC A4, Emericella nidulans FGSC A4
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