(16 nodes) DHS-like NAD/FAD-binding domain superfamily network (Aspergillus nidulans)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ANIA_10808	Thiamine pyrophosphate enzyme, putative (AFU_orthologue AFUA_2G13620); Belongs to the TPP enzyme family. (562 aa)
	ANIA_10214	2-hydroxyphytanoyl-CoA lyase, putative (AFU_orthologue AFUA_8G05230); Belongs to the TPP enzyme family. (605 aa)
	ANIA_11190	Uncharacterized protein. (612 aa)
	ANIA_08396	Pyruvate decarboxylase, putative (AFU_orthologue AFUA_6G00750). (575 aa)
	ANIA_04956	Acetolactate synthase. (687 aa)
	AN11873	NAD-dependent protein deacetylase hst2-2; NAD-dependent histone deacetylase, which could function in telomeric silencing, cell cycle progression and chromosome stability. Belongs to the sirtuin family. Class I subfamily. (354 aa)
	AN1226	NAD-dependent protein deacetylase hst4; NAD-dependent histone deacetylase, which could function in telomeric silencing, cell cycle progression and chromosome stability. Belongs to the sirtuin family. Class I subfamily. (595 aa)
	ANIA_01782	SIR2 family histone deacetylase, putative (AFU_orthologue AFUA_6G09210). (320 aa)
	ANIA_04345	Uncharacterized protein; Belongs to the TPP enzyme family. (606 aa)
	AN7461	NAD-dependent protein deacetylase hst2-1; NAD-dependent histone deacetylase, which could function in telomeric silencing, cell cycle progression and chromosome stability. Belongs to the sirtuin family. Class I subfamily. (361 aa)
	ANIA_06699	Electron transfer flavoprotein alpha subunit, putative (AFU_orthologue AFUA_7G05470). (349 aa)
	ANIA_11067	Silencing information regulator. (406 aa)
	AN10449	NAD-dependent protein deacetylase hst1; NAD-dependent histone deacetylase, which could function in telomeric silencing, cell cycle progression and chromosome stability. Belongs to the sirtuin family. Class I subfamily. (489 aa)
	ANIA_08075	Deoxyhypusine synthase, putative (AFU_orthologue AFUA_5G01740). (390 aa)
	ANIA_08130	Nicotinamide nucleotide transhydrogenase, putative (AFU_orthologue AFUA_5G02780). (131 aa)
	pdcA	Pyruvate decarboxylase; Belongs to the TPP enzyme family. (568 aa)

Your Current Organism:

Aspergillus nidulans

NCBI taxonomy Id: 227321
Other names: A. nidulans FGSC A4, Aspergillus nidulans FGSC A4, Emericella nidulans FGSC A4

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AN10449	AN11873	C8V3W5	P0CS88	NAD-dependent protein deacetylase hst1; NAD-dependent histone deacetylase, which could function in telomeric silencing, cell cycle progression and chromosome stability. Belongs to the sirtuin family. Class I subfamily.	NAD-dependent protein deacetylase hst2-2; NAD-dependent histone deacetylase, which could function in telomeric silencing, cell cycle progression and chromosome stability. Belongs to the sirtuin family. Class I subfamily.	0.483
AN10449	AN1226	C8V3W5	Q5BE04	NAD-dependent protein deacetylase hst1; NAD-dependent histone deacetylase, which could function in telomeric silencing, cell cycle progression and chromosome stability. Belongs to the sirtuin family. Class I subfamily.	NAD-dependent protein deacetylase hst4; NAD-dependent histone deacetylase, which could function in telomeric silencing, cell cycle progression and chromosome stability. Belongs to the sirtuin family. Class I subfamily.	0.506
AN10449	AN7461	C8V3W5	Q5AW69	NAD-dependent protein deacetylase hst1; NAD-dependent histone deacetylase, which could function in telomeric silencing, cell cycle progression and chromosome stability. Belongs to the sirtuin family. Class I subfamily.	NAD-dependent protein deacetylase hst2-1; NAD-dependent histone deacetylase, which could function in telomeric silencing, cell cycle progression and chromosome stability. Belongs to the sirtuin family. Class I subfamily.	0.473
AN11873	AN10449	P0CS88	C8V3W5	NAD-dependent protein deacetylase hst2-2; NAD-dependent histone deacetylase, which could function in telomeric silencing, cell cycle progression and chromosome stability. Belongs to the sirtuin family. Class I subfamily.	NAD-dependent protein deacetylase hst1; NAD-dependent histone deacetylase, which could function in telomeric silencing, cell cycle progression and chromosome stability. Belongs to the sirtuin family. Class I subfamily.	0.483
AN11873	AN1226	P0CS88	Q5BE04	NAD-dependent protein deacetylase hst2-2; NAD-dependent histone deacetylase, which could function in telomeric silencing, cell cycle progression and chromosome stability. Belongs to the sirtuin family. Class I subfamily.	NAD-dependent protein deacetylase hst4; NAD-dependent histone deacetylase, which could function in telomeric silencing, cell cycle progression and chromosome stability. Belongs to the sirtuin family. Class I subfamily.	0.415
AN11873	ANIA_01782	P0CS88	Q5BCE8	NAD-dependent protein deacetylase hst2-2; NAD-dependent histone deacetylase, which could function in telomeric silencing, cell cycle progression and chromosome stability. Belongs to the sirtuin family. Class I subfamily.	SIR2 family histone deacetylase, putative (AFU_orthologue AFUA_6G09210).	0.466
AN11873	ANIA_11067	P0CS88	C8V3N2	NAD-dependent protein deacetylase hst2-2; NAD-dependent histone deacetylase, which could function in telomeric silencing, cell cycle progression and chromosome stability. Belongs to the sirtuin family. Class I subfamily.	Silencing information regulator.	0.469
AN1226	AN10449	Q5BE04	C8V3W5	NAD-dependent protein deacetylase hst4; NAD-dependent histone deacetylase, which could function in telomeric silencing, cell cycle progression and chromosome stability. Belongs to the sirtuin family. Class I subfamily.	NAD-dependent protein deacetylase hst1; NAD-dependent histone deacetylase, which could function in telomeric silencing, cell cycle progression and chromosome stability. Belongs to the sirtuin family. Class I subfamily.	0.506
AN1226	AN11873	Q5BE04	P0CS88	NAD-dependent protein deacetylase hst4; NAD-dependent histone deacetylase, which could function in telomeric silencing, cell cycle progression and chromosome stability. Belongs to the sirtuin family. Class I subfamily.	NAD-dependent protein deacetylase hst2-2; NAD-dependent histone deacetylase, which could function in telomeric silencing, cell cycle progression and chromosome stability. Belongs to the sirtuin family. Class I subfamily.	0.415
AN1226	AN7461	Q5BE04	Q5AW69	NAD-dependent protein deacetylase hst4; NAD-dependent histone deacetylase, which could function in telomeric silencing, cell cycle progression and chromosome stability. Belongs to the sirtuin family. Class I subfamily.	NAD-dependent protein deacetylase hst2-1; NAD-dependent histone deacetylase, which could function in telomeric silencing, cell cycle progression and chromosome stability. Belongs to the sirtuin family. Class I subfamily.	0.937
AN1226	ANIA_01782	Q5BE04	Q5BCE8	NAD-dependent protein deacetylase hst4; NAD-dependent histone deacetylase, which could function in telomeric silencing, cell cycle progression and chromosome stability. Belongs to the sirtuin family. Class I subfamily.	SIR2 family histone deacetylase, putative (AFU_orthologue AFUA_6G09210).	0.938
AN7461	AN10449	Q5AW69	C8V3W5	NAD-dependent protein deacetylase hst2-1; NAD-dependent histone deacetylase, which could function in telomeric silencing, cell cycle progression and chromosome stability. Belongs to the sirtuin family. Class I subfamily.	NAD-dependent protein deacetylase hst1; NAD-dependent histone deacetylase, which could function in telomeric silencing, cell cycle progression and chromosome stability. Belongs to the sirtuin family. Class I subfamily.	0.473
AN7461	AN1226	Q5AW69	Q5BE04	NAD-dependent protein deacetylase hst2-1; NAD-dependent histone deacetylase, which could function in telomeric silencing, cell cycle progression and chromosome stability. Belongs to the sirtuin family. Class I subfamily.	NAD-dependent protein deacetylase hst4; NAD-dependent histone deacetylase, which could function in telomeric silencing, cell cycle progression and chromosome stability. Belongs to the sirtuin family. Class I subfamily.	0.937
AN7461	ANIA_01782	Q5AW69	Q5BCE8	NAD-dependent protein deacetylase hst2-1; NAD-dependent histone deacetylase, which could function in telomeric silencing, cell cycle progression and chromosome stability. Belongs to the sirtuin family. Class I subfamily.	SIR2 family histone deacetylase, putative (AFU_orthologue AFUA_6G09210).	0.943
AN7461	ANIA_11067	Q5AW69	C8V3N2	NAD-dependent protein deacetylase hst2-1; NAD-dependent histone deacetylase, which could function in telomeric silencing, cell cycle progression and chromosome stability. Belongs to the sirtuin family. Class I subfamily.	Silencing information regulator.	0.532
ANIA_01782	AN11873	Q5BCE8	P0CS88	SIR2 family histone deacetylase, putative (AFU_orthologue AFUA_6G09210).	NAD-dependent protein deacetylase hst2-2; NAD-dependent histone deacetylase, which could function in telomeric silencing, cell cycle progression and chromosome stability. Belongs to the sirtuin family. Class I subfamily.	0.466
ANIA_01782	AN1226	Q5BCE8	Q5BE04	SIR2 family histone deacetylase, putative (AFU_orthologue AFUA_6G09210).	NAD-dependent protein deacetylase hst4; NAD-dependent histone deacetylase, which could function in telomeric silencing, cell cycle progression and chromosome stability. Belongs to the sirtuin family. Class I subfamily.	0.938
ANIA_01782	AN7461	Q5BCE8	Q5AW69	SIR2 family histone deacetylase, putative (AFU_orthologue AFUA_6G09210).	NAD-dependent protein deacetylase hst2-1; NAD-dependent histone deacetylase, which could function in telomeric silencing, cell cycle progression and chromosome stability. Belongs to the sirtuin family. Class I subfamily.	0.943
ANIA_04345	ANIA_04956	Q5B535	C8V916	Uncharacterized protein; Belongs to the TPP enzyme family.	Acetolactate synthase.	0.608
ANIA_04345	ANIA_10808	Q5B535	C8V105	Uncharacterized protein; Belongs to the TPP enzyme family.	Thiamine pyrophosphate enzyme, putative (AFU_orthologue AFUA_2G13620); Belongs to the TPP enzyme family.	0.540