STRINGSTRING
ANIA_03110 ANIA_03110 hog1 hog1 mpkC mpkC ptkA ptkA tel1 tel1 ANIA_00144 ANIA_00144 ANIA_05815 ANIA_05815 ANIA_05982 ANIA_05982 ANIA_08285 ANIA_08285 ANIA_10515 ANIA_10515 mpkB mpkB ANIA_04563 ANIA_04563 ANIA_04536 ANIA_04536 ANIA_04935 ANIA_04935 ANIA_08751 ANIA_08751 ANIA_07695 ANIA_07695 ANIA_05666 ANIA_05666 ANIA_03450 ANIA_03450 ANIA_10193 ANIA_10193 plkA plkA ANIA_00106 ANIA_00106 sskB sskB ANIA_06363 ANIA_06363 ANIA_08261 ANIA_08261 schA schA pkaA pkaA cbk1 cbk1 nimA nimA nimX nimX cmkA cmkA ANIA_08836 ANIA_08836 ANIA_07737 ANIA_07737 ANIA_07572 ANIA_07572 ANIA_07537 ANIA_07537 ANIA_06508 ANIA_06508 imeB imeB ANIA_05973 ANIA_05973 ANIA_05759 ANIA_05759 ANIA_05757 ANIA_05757 ANIA_05728 ANIA_05728 ANIA_05674 ANIA_05674 ANIA_05529 ANIA_05529 ANIA_04980 ANIA_04980 ANIA_04717 ANIA_04717 sepH sepH ANIA_03065 ANIA_03065 bud32 bud32 ssn3 ssn3 ANIA_02265 ANIA_02265 ste20 ste20 atg1 atg1 ANIA_01485 ANIA_01485 ANIA_01171 ANIA_01171
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ANIA_03110Serine/threonine protein kinase, putative (AFU_orthologue AFUA_3G12670). (813 aa)
hog1Mitogen-activated protein kinase hog1; Mitogen-activated protein kinase involved in a signal transduction pathway that is activated by changes in the osmolarity of the extracellular environment. Controls osmotic regulation of transcription of target genes; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. HOG1 sub-subfamily. (379 aa)
mpkCMitogen-activated protein kinase mpkC; Mitogen-activated protein kinase required for growth on media where sorbitol or mannitol is the sole carbon source. (415 aa)
ptkASerine/threonine-protein kinase bur1; Serine/threonine-protein kinase involved in transcription regulation. Phosphorylates the UBC2/RAD6 ubiquitin-conjugating enzyme (E2), leading to monoubiquitination of histone H2B and the silencing of telomeric-associated genes. Also required for histone H3 methylation. Necessary for the recovery from pheromone-induced growth arrest in the cell cycle G1 phase (By similarity). (544 aa)
tel1Serine/threonine-protein kinase tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability (By similarity). (2793 aa)
ANIA_00144Serine/threonine protein kinase (Nrc-2), putative (AFU_orthologue AFUA_5G11520). (572 aa)
ANIA_05815Putative aurora kinase (Eurofung); Belongs to the protein kinase superfamily. (391 aa)
ANIA_05982TorA protein; Belongs to the PI3/PI4-kinase family. (2385 aa)
ANIA_08285Serine/threonine protein kinase (Kin28), putative (AFU_orthologue AFUA_7G03720). (296 aa)
ANIA_10515Serine/threonine protein kinase, putative (AFU_orthologue AFUA_1G05930). (996 aa)
mpkBMitogen-activated protein kinase. (354 aa)
ANIA_04563Casein kinase I (Eurofung); Belongs to the protein kinase superfamily. (370 aa)
ANIA_04536Serine/threonine protein kinase, putative (AFU_orthologue AFUA_2G02850). (1121 aa)
ANIA_04935Protein serine/threonine kinase (Ran1), putative (AFU_orthologue AFUA_3G10530); Belongs to the protein kinase superfamily. (436 aa)
ANIA_08751Non-specific serine/threonine protein kinase. (654 aa)
ANIA_07695Non-specific serine/threonine protein kinase. (616 aa)
ANIA_05666Mitogen-activated protein kinase. (330 aa)
ANIA_03450Serine/threonine protein kinase (Eurofung). (492 aa)
ANIA_10193Serine/threonine protein kinase, putative (AFU_orthologue AFUA_8G04670); Belongs to the protein kinase superfamily. (419 aa)
plkASerine/threonine-protein kinase. (1133 aa)
ANIA_00106Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (1085 aa)
sskBMAP kinase kinase kinase. (1313 aa)
ANIA_06363Serine/threonine-protein kinase RIO1; Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family. (558 aa)
ANIA_08261Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (366 aa)
schANon-specific serine/threonine protein kinase. (919 aa)
pkaAUncharacterized protein; Belongs to the protein kinase superfamily. (472 aa)
cbk1Serine/threonine-protein kinase cbk1; Protein kinase that seems to play a role in the regulation of cell morphogenesis and proliferation. (902 aa)
nimAG2-specific protein kinase nimA; Protein kinase that plays an important role in mitotic regulation. Seems to be phosphorylated and thereby activated by CDC2/cyclin B during mitotic activation. It is also required for spindle formation and for nuclear envelope breakdown. (699 aa)
nimXCyclin-dependent kinase 1; Plays a key role in the control of the eukaryotic cell cycle. It is required in higher cells for entry into S-phase and mitosis (By similarity). (323 aa)
cmkACalcium/calmodulin-dependent protein kinase cmkA; Calcium/calmodulin-dependent protein kinase. Required in nuclear division cycle for progression from G2 to mitosis. Required for hyphal growth. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily. (414 aa)
ANIA_08836Non-specific serine/threonine protein kinase. (825 aa)
ANIA_07737Serine/threonine protein kinase, putative (AFU_orthologue AFUA_5G07950). (510 aa)
ANIA_07572Glucose-repressible protein kinase (Eurofung). (2104 aa)
ANIA_07537Protein kinase, putative (AFU_orthologue AFUA_6G09240). (629 aa)
ANIA_06508Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (394 aa)
imeBSerine/threonine protein kinase ime2 homologue imeB (Eurofung). (781 aa)
ANIA_05973Non-specific serine/threonine protein kinase. (640 aa)
ANIA_05759Serine/threonine protein kinase, putative (AFU_orthologue AFUA_6G06720). (884 aa)
ANIA_05757Casein kinase I homolog, putative (AFU_orthologue AFUA_6G06870); Belongs to the protein kinase superfamily. (444 aa)
ANIA_05728Serine/threonine protein kinase, putative (AFU_orthologue AFUA_1G06920). (1202 aa)
ANIA_05674Ste20-like serine/threonine protein kinase, putative (AFU_orthologue AFUA_7G04330). (672 aa)
ANIA_05529COTA. (588 aa)
ANIA_04980Serine/threonine protein kinase, putative (Eurofung). (607 aa)
ANIA_04717cAMP-dependent protein kinase catalytic subunit (Eurofung); Belongs to the protein kinase superfamily. (396 aa)
sepHCytokinesis protein sepH; Required for early events during cytokinesis including localization of cytoskeletal components to the cytokinetic ring. Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC7 subfamily. (1346 aa)
ANIA_03065Calcium/calmodulin dependent protein kinase B; Belongs to the protein kinase superfamily. (404 aa)
bud32EKC/KEOPS complex subunit bud32; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. BUD32 has ATPase activity in the context of the EKC/KEOPS complex and likely plays a supporting role to the catalytic subunit KAE1. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is r [...] (285 aa)
ssn3Serine/threonine-protein kinase ssn3; Component of the srb8-11 complex. The srb8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription. The srb8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator. It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex. The srb8-11 complex phosphorylates the C-terminal domain (CTD) of the largest subunit of RNA polymerase II (By similarity). (426 aa)
ANIA_02265Serine/threonine protein kinase, putative (AFU_orthologue AFUA_5G06470). (641 aa)
ste20Serine/threonine-protein kinase ste20; MAP4K component of the MAPK pathway required for the mating pheromone response and the regulation of cell polarity and cell cycle. Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. (848 aa)
atg1Serine/threonine-protein kinase atg1; Serine/threonine protein kinase involved in the cytoplasm to vacuole transport (Cvt) and found to be essential in autophagy, where it is required for the formation of autophagosomes. Involved in the clearance of protein aggregates which cannot be efficiently cleared by the proteasome. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing [...] (935 aa)
ANIA_01485Casein kinase II (Eurofung); Belongs to the protein kinase superfamily. (333 aa)
ANIA_01171Non-specific serine/threonine protein kinase. (922 aa)
Your Current Organism:
Aspergillus nidulans
NCBI taxonomy Id: 227321
Other names: A. nidulans FGSC A4, Aspergillus nidulans FGSC A4, Emericella nidulans FGSC A4
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