35 items (Aspergillus nidulans) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ANIA_08302	Uncharacterized protein. (618 aa)
	ANIA_08221	Uncharacterized protein. (450 aa)
	ANIA_07102	Uncharacterized protein. (172 aa)
	ANIA_05511	Protein kinase domain-containing protein. (429 aa)
	ANIA_05495	Ubiquitin conjugating enzyme (UbcK), putative (AFU_orthologue AFUA_6G13170); Belongs to the ubiquitin-conjugating enzyme family. (181 aa)
	asf1	Histone chaperone asf1; Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. (279 aa)
	ANIA_04735	Anaphase-promoting complex subunit Apc5, putative (AFU_orthologue AFUA_3G06200). (715 aa)
	ANIA_04189	Putative MAPKK (Eurofung). (502 aa)
	ANIA_03736	Uncharacterized protein. (360 aa)
	ANIA_03619	Subunit of MRX complex (Eurofung). (1319 aa)
	ANIA_03422	MAP kinase kinase (Eurofung). (539 aa)
	ANIA_03271	Uncharacterized protein. (427 aa)
	ANIA_02770	HUN domain-containing protein. (670 aa)
	hir1	Protein hir1; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family. (1031 aa)
	ANIA_02141	Pot1-like protein. (426 aa)
	ANIA_01149	Uncharacterized protein. (142 aa)
	ANIA_01067	Antibiotic biosynthesis monooxygenase, putative (AFU_orthologue AFUA_1G12025). (109 aa)
	pbsA	MAP kinase kinase (Eurofung). (651 aa)
	ANIA_00556	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (818 aa)
	ANIA_00219	SET domain protein (AFU_orthologue AFUA_4G09180). (598 aa)
	tel1	Serine/threonine-protein kinase tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability (By similarity). (2793 aa)
	ANIA_10091	37S ribosomal protein mrp10, mitochondrial; Involved in mitochondrial genome encoded proteins translation. (97 aa)
	ANIA_01159	Ubiquitin conjugating enzyme E2, putative (AFU_orthologue AFUA_1G11410); Belongs to the ubiquitin-conjugating enzyme family. (470 aa)
	ANIA_10365	Ubiquitin conjugating enzyme (UbcB), putative (AFU_orthologue AFUA_3G12850). (178 aa)
	ANIA_05666	Mitogen-activated protein kinase. (330 aa)
	ANIA_10731	Protein kinase domain-containing protein. (96 aa)
	ANIA_08571	Thioredoxin, putative (AFU_orthologue AFUA_6G10300). (108 aa)
	ANIA_04872	Ubiquitin-like domain-containing protein. (154 aa)
	esa1	Histone acetyltransferase esa1; Catalytic component of the NuA4 histone acetyltransferase (HAT) complex which is involved in epigenetic transcriptional activation of selected genes principally by acetylation of nucleosomal histones H4, H3, H2B, H2A and H2A variant H2A.Z. Acetylates histone H4 to form H4K5ac, H4K8ac, H4K12ac and H4K16ac, histone H3 to form H3K14ac, histone H2B to form H2BK16ac, and histone H2A to form H2AK4ac and H2AK7ac. Acetylation of histone H4 is essential for DNA double- strand break repair through homologous recombination. Involved in cell cycle progression. Recru [...] (508 aa)
	ANIA_04324	Putative b-zip transcription factor (Eurofung). (263 aa)
	mpkB	Mitogen-activated protein kinase. (354 aa)
	TRX1	Thioredoxin; Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. (110 aa)
	htbA	Histone H2B; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (140 aa)
	ANIA_02269	Uncharacterized protein. (886 aa)
	swr1	Helicase swr1; Catalytic component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling; Belongs to the SNF2/RAD54 helicase family. SWR1 subfamily. (1698 aa)

Your Current Organism:

Aspergillus nidulans

NCBI taxonomy Id: 227321
Other names: A. nidulans FGSC A4, Aspergillus nidulans FGSC A4, Emericella nidulans FGSC A4

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANIA_00219	ANIA_01159	Q5BGW1	C8VT35	SET domain protein (AFU_orthologue AFUA_4G09180).	Ubiquitin conjugating enzyme E2, putative (AFU_orthologue AFUA_1G11410); Belongs to the ubiquitin-conjugating enzyme family.	0.632
ANIA_00219	ANIA_04324	Q5BGW1	C8V968	SET domain protein (AFU_orthologue AFUA_4G09180).	Putative b-zip transcription factor (Eurofung).	0.607
ANIA_00219	ANIA_04735	Q5BGW1	Q5B3Z5	SET domain protein (AFU_orthologue AFUA_4G09180).	Anaphase-promoting complex subunit Apc5, putative (AFU_orthologue AFUA_3G06200).	0.641
ANIA_00219	ANIA_04872	Q5BGW1	G5EB17	SET domain protein (AFU_orthologue AFUA_4G09180).	Ubiquitin-like domain-containing protein.	0.607
ANIA_00219	ANIA_05495	Q5BGW1	Q5B1T5	SET domain protein (AFU_orthologue AFUA_4G09180).	Ubiquitin conjugating enzyme (UbcK), putative (AFU_orthologue AFUA_6G13170); Belongs to the ubiquitin-conjugating enzyme family.	0.617
ANIA_00219	ANIA_07102	Q5BGW1	Q5AX78	SET domain protein (AFU_orthologue AFUA_4G09180).	Uncharacterized protein.	0.469
ANIA_00219	htbA	Q5BGW1	P23754	SET domain protein (AFU_orthologue AFUA_4G09180).	Histone H2B; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	0.403
ANIA_00556	ANIA_02141	Q5BFX4	Q5BBD9	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	Pot1-like protein.	0.521
ANIA_00556	ANIA_03619	Q5BFX4	Q5B761	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	Subunit of MRX complex (Eurofung).	0.999
ANIA_00556	ANIA_04324	Q5BFX4	C8V968	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	Putative b-zip transcription factor (Eurofung).	0.538
ANIA_00556	ANIA_04872	Q5BFX4	G5EB17	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	Ubiquitin-like domain-containing protein.	0.538
ANIA_00556	ANIA_10365	Q5BFX4	C8VIJ3	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	Ubiquitin conjugating enzyme (UbcB), putative (AFU_orthologue AFUA_3G12850).	0.439
ANIA_00556	esa1	Q5BFX4	C8VBH4	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	Histone acetyltransferase esa1; Catalytic component of the NuA4 histone acetyltransferase (HAT) complex which is involved in epigenetic transcriptional activation of selected genes principally by acetylation of nucleosomal histones H4, H3, H2B, H2A and H2A variant H2A.Z. Acetylates histone H4 to form H4K5ac, H4K8ac, H4K12ac and H4K16ac, histone H3 to form H3K14ac, histone H2B to form H2BK16ac, and histone H2A to form H2AK4ac and H2AK7ac. Acetylation of histone H4 is essential for DNA double- strand break repair through homologous recombination. Involved in cell cycle progression. Recru [...]	0.580
ANIA_00556	htbA	Q5BFX4	P23754	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	Histone H2B; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	0.516
ANIA_00556	tel1	Q5BFX4	Q5BHE2	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	Serine/threonine-protein kinase tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability (By similarity).	0.982
ANIA_01159	ANIA_00219	C8VT35	Q5BGW1	Ubiquitin conjugating enzyme E2, putative (AFU_orthologue AFUA_1G11410); Belongs to the ubiquitin-conjugating enzyme family.	SET domain protein (AFU_orthologue AFUA_4G09180).	0.632
ANIA_01159	ANIA_04324	C8VT35	C8V968	Ubiquitin conjugating enzyme E2, putative (AFU_orthologue AFUA_1G11410); Belongs to the ubiquitin-conjugating enzyme family.	Putative b-zip transcription factor (Eurofung).	0.834
ANIA_01159	ANIA_04735	C8VT35	Q5B3Z5	Ubiquitin conjugating enzyme E2, putative (AFU_orthologue AFUA_1G11410); Belongs to the ubiquitin-conjugating enzyme family.	Anaphase-promoting complex subunit Apc5, putative (AFU_orthologue AFUA_3G06200).	0.982
ANIA_01159	ANIA_04872	C8VT35	G5EB17	Ubiquitin conjugating enzyme E2, putative (AFU_orthologue AFUA_1G11410); Belongs to the ubiquitin-conjugating enzyme family.	Ubiquitin-like domain-containing protein.	0.834
ANIA_01159	ANIA_05495	C8VT35	Q5B1T5	Ubiquitin conjugating enzyme E2, putative (AFU_orthologue AFUA_1G11410); Belongs to the ubiquitin-conjugating enzyme family.	Ubiquitin conjugating enzyme (UbcK), putative (AFU_orthologue AFUA_6G13170); Belongs to the ubiquitin-conjugating enzyme family.	0.976