STRINGSTRING
hhfA hhfA ANIA_06260 ANIA_06260 ANIA_06604 ANIA_06604 ANIA_06675 ANIA_06675 ANIA_07475 ANIA_07475 ANIA_08643 ANIA_08643 ANIA_09517 ANIA_09517 htbA htbA hhfB hhfB ANIA_09358 ANIA_09358 ANIA_02911 ANIA_02911 ANIA_05657 ANIA_05657 ANIA_10551 ANIA_10551 ANIA_06849 ANIA_06849 hat1 hat1 swc4 swc4 ANIA_02294 ANIA_02294 eaf3 eaf3 ANIA_01004 ANIA_01004 ANIA_00719 ANIA_00719 ANIA_00668 ANIA_00668 rvb2 rvb2 ANIA_00191 ANIA_00191
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
hhfAHistone H4.1; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
ANIA_06260PAPA-1-like conserved region protein (AFU_orthologue AFUA_2G12960). (385 aa)
ANIA_06604Killer toxin sensitivity protein (Iki1), putative (AFU_orthologue AFUA_6G04170). (350 aa)
ANIA_06675PHD finger domain protein, putative (AFU_orthologue AFUA_7G05250). (1173 aa)
ANIA_07475Signal transducer, putative (AFU_orthologue AFUA_2G05620). (793 aa)
ANIA_08643BZIP transcription factor (Atf21), putative (AFU_orthologue AFUA_5G12960). (359 aa)
ANIA_09517BAH domain-containing protein. (425 aa)
htbAHistone H2B; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (140 aa)
hhfBHistone H4.2; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
ANIA_09358Putative CCAAT-box-binding transcription factor (Eurofung). (145 aa)
ANIA_02911AtfA. (485 aa)
ANIA_05657Uncharacterized protein. (420 aa)
ANIA_10551Elongator complex protein 1; Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in transcriptional elongation. Belongs to the ELP1/IKA1 family. (1338 aa)
ANIA_06849BZIP transcription factor (Atf21), putative (AFU_orthologue AFUA_5G12960). (322 aa)
hat1Histone acetyltransferase type B catalytic subunit; Catalytic component of the histone acetylase B (HAT-B) complex. Acetylates 'Lys-12' of histone H4 which is required for telomeric silencing. Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. Involved in DNA double-strand break repair (By similarity); Belongs to the HAT1 family. (496 aa)
swc4SWR1-complex protein 4; Component of the SWR1 complex which mediates the ATP- dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (By similarity). (586 aa)
ANIA_02294Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. (574 aa)
eaf3Chromatin modification-related protein eaf3; Involved in deacetylation of histones, chromatin assembly and chromosome segregation. May act as a transcriptional oscillator, directing histone deacetylases to specific chromosomal domains. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (By similarity). (327 aa)
ANIA_01004Uncharacterized protein. (222 aa)
ANIA_00719SAGA-like transcriptional regulatory complex subunit Spt3, putative (AFU_orthologue AFUA_1G14030). (331 aa)
ANIA_00668SAGA complex component (Sgf29), putative (AFU_orthologue AFUA_1G13290). (462 aa)
rvb2RuvB-like helicase 2; DNA helicase which participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. The SWR1 complex mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. The INO80 complex remodels chromatin by shifting nucleosomes and is involved in DNA repair. Also involved in pre-rRNA processing (By similarity); Belongs to the RuvB family. (468 aa)
ANIA_00191PAXNEB protein superfamily (AFU_orthologue AFUA_5G11130). (391 aa)
Your Current Organism:
Aspergillus nidulans
NCBI taxonomy Id: 227321
Other names: A. nidulans FGSC A4, Aspergillus nidulans FGSC A4, Emericella nidulans FGSC A4
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