STRINGSTRING
ANIA_02431 ANIA_02431 ANIA_05873 ANIA_05873 ANIA_06540 ANIA_06540 ANIA_06600 ANIA_06600 ANIA_06738 ANIA_06738 ANIA_06898 ANIA_06898 ANIA_04281 ANIA_04281 ANIA_03589 ANIA_03589 ANIA_08079 ANIA_08079 ANIA_08244 ANIA_08244 ANIA_03691 ANIA_03691 ANIA_05082 ANIA_05082 ANIA_10627 ANIA_10627 ANIA_09435 ANIA_09435 ANIA_04417 ANIA_04417 ANIA_04399 ANIA_04399 ANIA_10546 ANIA_10546 ANIA_04324 ANIA_04324 ANIA_11113 ANIA_11113 ANIA_04713 ANIA_04713 ANIA_04664 ANIA_04664 ANIA_10694 ANIA_10694 ANIA_05482 ANIA_05482 ANIA_03451 ANIA_03451 ANIA_03062 ANIA_03062 ANIA_02176 ANIA_02176 plkA plkA ANIA_10002 ANIA_10002 ANIA_00696 ANIA_00696 ANIA_01365 ANIA_01365 ANIA_10112 ANIA_10112 ANIA_01190 ANIA_01190 ANIA_01159 ANIA_01159 kipB kipB ANIA_00906 ANIA_00906 ANIA_04872 ANIA_04872 ANIA_05627 ANIA_05627 apsB apsB nudE nudE htaA htaA benA benA tubC tubC nimA nimA nudC nudC mipA mipA hhfA hhfA hhfB hhfB htbA htbA tubA tubA tubB tubB bimB bimB myoA myoA sudA sudA ANIA_08923 ANIA_08923 ANIA_08315 ANIA_08315 ANIA_08170 ANIA_08170 ANIA_08120 ANIA_08120 ANIA_08076 ANIA_08076 ANIA_08056 ANIA_08056 htz1 htz1 ANIA_07836 ANIA_07836 ANIA_07572 ANIA_07572 ANIA_07499 ANIA_07499 ANIA_07465 ANIA_07465 ANIA_07310 ANIA_07310 ANIA_07296 ANIA_07296 ANIA_06980 ANIA_06980 ANIA_06978 ANIA_06978 ANIA_06920 ANIA_06920 ANIA_06562 ANIA_06562 ANIA_06323 ANIA_06323 ANIA_05899 ANIA_05899 ANIA_05889 ANIA_05889 alpA alpA ANIA_05512 ANIA_05512 jip5 jip5 ANIA_05115 ANIA_05115 ndc80 ndc80 ANIA_04867 ANIA_04867 ANIA_04862 ANIA_04862 ANIA_04597 ANIA_04597 ANIA_04596 ANIA_04596 ANIA_04499 ANIA_04499 ANIA_04293 ANIA_04293 ANIA_04265 ANIA_04265 snf7 snf7 ANIA_04094 ANIA_04094 ANIA_04045 ANIA_04045 ANIA_03910 ANIA_03910 ANIA_03818 ANIA_03818 ANIA_03806 ANIA_03806 ANIA_03574 ANIA_03574 ANIA_03061 ANIA_03061 ANIA_02963 ANIA_02963 ANIA_02874 ANIA_02874 ANIA_02862 ANIA_02862 ANIA_02631 ANIA_02631 ANIA_02408 ANIA_02408 ANIA_02143 ANIA_02143 ANIA_02086 ANIA_02086 mdm34 mdm34 ANIA_01626 ANIA_01626 ANIA_01485 ANIA_01485 ANIA_01475 ANIA_01475 spc25 spc25 ANIA_01383 ANIA_01383 AN1361 AN1361 ANIA_01356 ANIA_01356 ANIA_01343 ANIA_01343 ANIA_01272 ANIA_01272 ANIA_01238 ANIA_01238 sumO sumO ANIA_01026 ANIA_01026 ANIA_01005 ANIA_01005 ANIA_00802 ANIA_00802 ANIA_00725 ANIA_00725 ANIA_00704 ANIA_00704 nuf2 nuf2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ANIA_02431Nuclear pore complex protein An-Nup49 (Eurofung). (473 aa)
ANIA_05873Spindle pole body component. (875 aa)
ANIA_06540Mitochondrial mRNA processing protein PET127, putative (AFU_orthologue AFUA_6G04720). (727 aa)
ANIA_06600Mis6 domain protein (AFU_orthologue AFUA_6G04100). (740 aa)
ANIA_06738Nuclear pore complex protein An-Nup170 (Eurofung). (1346 aa)
ANIA_06898SNF7 family protein (AFU_orthologue AFUA_5G13410). (226 aa)
ANIA_04281GTP-binding protein ypt1 (Broad). (201 aa)
ANIA_03589Dynamitin homolog (P50 subunit of dynactin) (Eurofung). (467 aa)
ANIA_08079Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit. (680 aa)
ANIA_08244SNAD. (811 aa)
ANIA_03691AAA family ATPase, putative (AFU_orthologue AFUA_6G12560); Belongs to the AAA ATPase family. (803 aa)
ANIA_05082Miscellaneous Zn(II)2Cys6 transcription factor (Eurofung); Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (353 aa)
ANIA_10627Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (389 aa)
ANIA_09435Uncharacterized protein. (769 aa)
ANIA_04417Nuclear pore complex protein An-Ndc1 (Eurofung). (650 aa)
ANIA_04399Ubiquitin carrier protein; Belongs to the ubiquitin-conjugating enzyme family. (157 aa)
ANIA_10546Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (368 aa)
ANIA_04324Putative b-zip transcription factor (Eurofung). (263 aa)
ANIA_11113Rad21/Rec8 N terminal domain protein (AFU_orthologue AFUA_6G02900). (737 aa)
ANIA_04713Ser/Thr protein phosphatase family (AFU_orthologue AFUA_5G08620). (259 aa)
ANIA_04664Dynein light intermediate chain (Eurofung). (505 aa)
ANIA_10694Uncharacterized protein. (623 aa)
ANIA_05482GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (215 aa)
ANIA_03451Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. (1189 aa)
ANIA_03062Calmodulin-binding coil-coil protein. (1207 aa)
ANIA_02176Spindle pole body component. (772 aa)
plkASerine/threonine-protein kinase. (1133 aa)
ANIA_10002Nuclear pore complex protein AN-Nup192 (Eurofung). (1673 aa)
ANIA_00696M protein repeat protein (AFU_orthologue AFUA_1G13580). (666 aa)
ANIA_01365SNF7 family protein (AFU_orthologue AFUA_1G09220). (208 aa)
ANIA_10112Nuclear pore complex protein An-Nup188 (Eurofung). (1515 aa)
ANIA_01190Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). (1045 aa)
ANIA_01159Ubiquitin conjugating enzyme E2, putative (AFU_orthologue AFUA_1G11410); Belongs to the ubiquitin-conjugating enzyme family. (470 aa)
kipBKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (989 aa)
ANIA_00906Importin N-terminal domain-containing protein. (872 aa)
ANIA_04872Ubiquitin-like domain-containing protein. (154 aa)
ANIA_05627Peptidase S59 domain-containing protein. (1962 aa)
apsBAnucleate primary sterigmata protein B; Involved in regulation of nuclear migration. May be involved in regulating nuclear positioning. (1051 aa)
nudENuclear distribution protein nudE; Required for nuclear migration within hyphae during vegetative growth; Belongs to the nudE family. (586 aa)
htaAHistone H2A; Core component of nucleosome which plays a central role in DNA double strand break (DSB) repair. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (132 aa)
benATubulin beta-1 chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (447 aa)
tubCTubulin beta-2 chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain; Belongs to the tubulin family. (449 aa)
nimAG2-specific protein kinase nimA; Protein kinase that plays an important role in mitotic regulation. Seems to be phosphorylated and thereby activated by CDC2/cyclin B during mitotic activation. It is also required for spindle formation and for nuclear envelope breakdown. (699 aa)
nudCNuclear movement protein nudC; Required for nuclear movement. May interact between microtubules and nuclei and/or may be involved in the generation of force used to move nuclei during interphase; Belongs to the nudC family. (198 aa)
mipATubulin gamma chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle pole or the centrosome, suggesting that it is involved in the minus-end nucleation of microtubule assembly. Interacts physically with beta-tubulin and is involved in microtubule function. (454 aa)
hhfAHistone H4.1; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
hhfBHistone H4.2; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
htbAHistone H2B; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (140 aa)
tubATubulin alpha-1 chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa)
tubBTubulin alpha-2 chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
bimBSeparin; Required for nuclear division. Could function in the mitotic spindle. (2067 aa)
myoAMyosin-1; Type-I myosin implicated in the organization of the actin cytoskeleton. Required for proper actin cytoskeleton polarization. At the cell cortex, assembles in patch-like structures together with proteins from the actin-polymerizing machinery and promotes actin assembly. Functions as actin nucleation-promoting factor (NPF) for the Arp2/3 complex (By similarity). Plays an important role in polarized growth, spore germination, hyphal morphogenesis, and septal wall formation. (1249 aa)
sudAChromosome segregation protein sudA; Involved in chromosome segregation in mitosis; Belongs to the SMC family. SMC3 subfamily. (1215 aa)
ANIA_08923HET domain-containing protein. (793 aa)
ANIA_08315Uncharacterized protein. (345 aa)
ANIA_08170Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family. (356 aa)
ANIA_08120Spindle pole body component. (905 aa)
ANIA_08076MYB DNA-binding domain protein (AFU_orthologue AFUA_5G01730). (2044 aa)
ANIA_08056Hypothetical nuclear condensin complex subunit 3 (Eurofung). (1114 aa)
htz1Histone H2A.Z; Variant histone H2A which can replace H2A in some nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. This variant is enriched at promoters, it may keep them in a repressed state until the appropriate activa [...] (136 aa)
ANIA_07836Cysteine-rich secreted protein (AFU_orthologue AFUA_7G01060). (335 aa)
ANIA_07572Glucose-repressible protein kinase (Eurofung). (2104 aa)
ANIA_07499Sister chromatid cohesion protein. (1768 aa)
ANIA_07465Double-strand-break repair protein rad21 (AFU_orthologue AFUA_2G05850). (584 aa)
ANIA_07310Vacuolar sorting protein SNF7 family protein, putative (AFU_orthologue AFUA_2G16692). (473 aa)
ANIA_07296BimD protein. (1506 aa)
ANIA_06980Nuclear pore complex protein An-Nic96 (Eurofung). (1048 aa)
ANIA_06978RCC1 Chromatin-associated guanine nucleotide exchange factor for Ran (Eurofung). (533 aa)
ANIA_06920SNF7 family protein (AFU_orthologue AFUA_5G13890). (228 aa)
ANIA_06562NIF domain protein (AFU_orthologue AFUA_6G04580). (619 aa)
ANIA_06323P150 dynactin NUDM. (1267 aa)
ANIA_05899Chromosome segregation protein sudA. (1179 aa)
ANIA_05889WD40 protein related to S. cerevisiae SEH1 (Eurofung); Belongs to the WD repeat SEC13 family. (342 aa)
alpADis1/XMAP215 protein AlpA (Eurofung). (891 aa)
ANIA_05512Magnesium dependent phosphatase, putative (AFU_orthologue AFUA_6G13100). (215 aa)
jip5WD repeat-containing protein jip5. (410 aa)
ANIA_05115Cupin domain protein (AFU_orthologue AFUA_1G07590). (552 aa)
ndc80Probable kinetochore protein ndc80; Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. (738 aa)
ANIA_04867Spindle pole body component. (968 aa)
ANIA_04862Ran specific GTPase activating protein An-RanGAP (Eurofung). (417 aa)
ANIA_04597Chromosome segregation protein sudA. (1476 aa)
ANIA_04596ELYS domain-containing protein. (317 aa)
ANIA_04499Nuclear pore complex protein An-Nsp1 (Eurofung). (624 aa)
ANIA_04293Nuclear pore complex protein An-Nup133 (Eurofung). (1293 aa)
ANIA_04265Condensin complex subunit 2; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. (886 aa)
snf7Vacuolar-sorting protein snf7; Required for the sorting and concentration of proteins resulting in the entry of these proteins into the invaginating vesicles of the multivesicular body (MVB). (242 aa)
ANIA_04094C-14 sterol reductase (AFU_orthologue AFUA_1G03150). (496 aa)
ANIA_04045Spo7-like protein (AFU_orthologue AFUA_1G03910). (463 aa)
ANIA_03910Sister chromatid separation protein (Src1), putative (AFU_orthologue AFUA_6G08530). (700 aa)
ANIA_03818Uncharacterized protein. (348 aa)
ANIA_03806Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (482 aa)
ANIA_03574Uncharacterized protein. (383 aa)
ANIA_03061Vacuolar sorting ATPase Vps4, putative (AFU_orthologue AFUA_3G09360); Belongs to the AAA ATPase family. (434 aa)
ANIA_02963Chromosome segregation protein sudA. (1261 aa)
ANIA_02874Uncharacterized protein. (1365 aa)
ANIA_02862EB1 homolog (Eurofung). (246 aa)
ANIA_02631Alpha-L-rhamnosidase C, putative (AFU_orthologue AFUA_3G02880). (568 aa)
ANIA_02408HET domain protein (AFU_orthologue AFUA_1G17550). (778 aa)
ANIA_02143Nuclear cohesin complex subunit (Psc3), putative (AFU_orthologue AFUA_2G16080). (1195 aa)
ANIA_02086Nuclear pore complex protein An-Nup159 (Eurofung). (1394 aa)
mdm34Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. Mdm34 is required for the interaction of the ER-resident membrane protein mmm1 and the outer mitochondrial membrane-resident beta-barrel protein mdm10. (561 aa)
ANIA_01626Uncharacterized protein. (578 aa)
ANIA_01485Casein kinase II (Eurofung); Belongs to the protein kinase superfamily. (333 aa)
ANIA_01475Clip 170 homolog (Eurofung). (668 aa)
spc25Probable kinetochore protein spc25; Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. (257 aa)
ANIA_01383mRNA stability protein; Plays an essential role in initiation of the G0 program by preventing the degradation of specific nutrient-regulated mRNAs via the 5'-3' mRNA decay pathway. (166 aa)
AN1361Mitotic-spindle organizing protein 1; Required for gamma-tubulin complex recruitment to the microtubule organizing center (MTOC). (74 aa)
ANIA_01356Uncharacterized protein. (415 aa)
ANIA_01343NIF domain protein (AFU_orthologue AFUA_1G09460). (515 aa)
ANIA_01272Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (264 aa)
ANIA_01238Nuclear pore complex protein An-Nup120 (Eurofung). (1298 aa)
sumOUbiquitin-like domain-containing protein. (94 aa)
ANIA_01026Uncharacterized protein. (326 aa)
ANIA_01005Spindle pole body component. (952 aa)
ANIA_00802Lipin Smp2, putative (AFU_orthologue AFUA_1G14610). (730 aa)
ANIA_00725DUF292 domian protein (AFU_orthologue AFUA_1G13960). (405 aa)
ANIA_00704Centrin-binding protein Sfi1, putative (AFU_orthologue AFUA_1G13700). (1080 aa)
nuf2Probable kinetochore protein nuf2; Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. (463 aa)
Your Current Organism:
Aspergillus nidulans
NCBI taxonomy Id: 227321
Other names: A. nidulans FGSC A4, Aspergillus nidulans FGSC A4, Emericella nidulans FGSC A4
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