node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ANIA_03675 | enoA | Q5B705 | Q5B135 | CPCA. | Enolase; Involved in osmoadaptation. | 0.584 |
ANIA_03675 | hog1 | Q5B705 | Q9P419 | CPCA. | Mitogen-activated protein kinase hog1; Mitogen-activated protein kinase involved in a signal transduction pathway that is activated by changes in the osmolarity of the extracellular environment. Controls osmotic regulation of transcription of target genes; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. HOG1 sub-subfamily. | 0.457 |
ANIA_03675 | sidA | Q5B705 | G5EB76 | CPCA. | L-ornithine N(5)-monooxygenase; Catalyzes the conversion of L-ornithine to N(5)- hydroxyornithine, the first step in the biosynthesis of all hydroxamate-containing siderophores, such as the secreted triacetylfusarinine C (TAFC) involved in iron uptake and the intracellular iron storage compound desferriferricrocin (DFFC). | 0.584 |
ANIA_03675 | sreA | Q5B705 | G5EB20 | CPCA. | GATA-type transcription factor sreA; GATA-type transcription repressor that regulates iron- acquisition genes through specific binding GATA sequence elements of target promoters. Iron acquisition regulation is critical for survival under both iron-limiting conditions (to acquire essential iron) and iron-replete conditions (to limit iron toxicity). SreA targets include genes encoding a number of key iron-regulated factors such as those involved in siderophore biosynthesis. | 0.743 |
ANIA_03675 | trpC | Q5B705 | P06531 | CPCA. | Multifunctional tryptophan biosynthesis protein; Trifunctional enzyme bearing the Gln amidotransferase (GATase) domain of anthranilate synthase, indole-glycerolphosphate synthase, and phosphoribosylanthranilate isomerase activities. | 0.573 |
cycA | niaD | P38091 | P22945 | Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. | Nitrate reductase [NADPH]; Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria. | 0.849 |
cycA | sreA | P38091 | G5EB20 | Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. | GATA-type transcription factor sreA; GATA-type transcription repressor that regulates iron- acquisition genes through specific binding GATA sequence elements of target promoters. Iron acquisition regulation is critical for survival under both iron-limiting conditions (to acquire essential iron) and iron-replete conditions (to limit iron toxicity). SreA targets include genes encoding a number of key iron-regulated factors such as those involved in siderophore biosynthesis. | 0.726 |
enoA | ANIA_03675 | Q5B135 | Q5B705 | Enolase; Involved in osmoadaptation. | CPCA. | 0.584 |
enoA | sidA | Q5B135 | G5EB76 | Enolase; Involved in osmoadaptation. | L-ornithine N(5)-monooxygenase; Catalyzes the conversion of L-ornithine to N(5)- hydroxyornithine, the first step in the biosynthesis of all hydroxamate-containing siderophores, such as the secreted triacetylfusarinine C (TAFC) involved in iron uptake and the intracellular iron storage compound desferriferricrocin (DFFC). | 0.623 |
enoA | sreA | Q5B135 | G5EB20 | Enolase; Involved in osmoadaptation. | GATA-type transcription factor sreA; GATA-type transcription repressor that regulates iron- acquisition genes through specific binding GATA sequence elements of target promoters. Iron acquisition regulation is critical for survival under both iron-limiting conditions (to acquire essential iron) and iron-replete conditions (to limit iron toxicity). SreA targets include genes encoding a number of key iron-regulated factors such as those involved in siderophore biosynthesis. | 0.584 |
enoA | trpC | Q5B135 | P06531 | Enolase; Involved in osmoadaptation. | Multifunctional tryptophan biosynthesis protein; Trifunctional enzyme bearing the Gln amidotransferase (GATase) domain of anthranilate synthase, indole-glycerolphosphate synthase, and phosphoribosylanthranilate isomerase activities. | 0.415 |
hog1 | ANIA_03675 | Q9P419 | Q5B705 | Mitogen-activated protein kinase hog1; Mitogen-activated protein kinase involved in a signal transduction pathway that is activated by changes in the osmolarity of the extracellular environment. Controls osmotic regulation of transcription of target genes; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. HOG1 sub-subfamily. | CPCA. | 0.457 |
mirA | sidA | Q8X1Z7 | G5EB76 | Siderophore iron transporter mirA; Involved in the transport of siderophore enterobactin and so has a role in iron homeostasis; Belongs to the major facilitator superfamily. | L-ornithine N(5)-monooxygenase; Catalyzes the conversion of L-ornithine to N(5)- hydroxyornithine, the first step in the biosynthesis of all hydroxamate-containing siderophores, such as the secreted triacetylfusarinine C (TAFC) involved in iron uptake and the intracellular iron storage compound desferriferricrocin (DFFC). | 0.408 |
mirA | sreA | Q8X1Z7 | G5EB20 | Siderophore iron transporter mirA; Involved in the transport of siderophore enterobactin and so has a role in iron homeostasis; Belongs to the major facilitator superfamily. | GATA-type transcription factor sreA; GATA-type transcription repressor that regulates iron- acquisition genes through specific binding GATA sequence elements of target promoters. Iron acquisition regulation is critical for survival under both iron-limiting conditions (to acquire essential iron) and iron-replete conditions (to limit iron toxicity). SreA targets include genes encoding a number of key iron-regulated factors such as those involved in siderophore biosynthesis. | 0.678 |
niaD | cycA | P22945 | P38091 | Nitrate reductase [NADPH]; Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria. | Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. | 0.849 |
niaD | sreA | P22945 | G5EB20 | Nitrate reductase [NADPH]; Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria. | GATA-type transcription factor sreA; GATA-type transcription repressor that regulates iron- acquisition genes through specific binding GATA sequence elements of target promoters. Iron acquisition regulation is critical for survival under both iron-limiting conditions (to acquire essential iron) and iron-replete conditions (to limit iron toxicity). SreA targets include genes encoding a number of key iron-regulated factors such as those involved in siderophore biosynthesis. | 0.468 |
niaD | trpC | P22945 | P06531 | Nitrate reductase [NADPH]; Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria. | Multifunctional tryptophan biosynthesis protein; Trifunctional enzyme bearing the Gln amidotransferase (GATase) domain of anthranilate synthase, indole-glycerolphosphate synthase, and phosphoribosylanthranilate isomerase activities. | 0.448 |
sidA | ANIA_03675 | G5EB76 | Q5B705 | L-ornithine N(5)-monooxygenase; Catalyzes the conversion of L-ornithine to N(5)- hydroxyornithine, the first step in the biosynthesis of all hydroxamate-containing siderophores, such as the secreted triacetylfusarinine C (TAFC) involved in iron uptake and the intracellular iron storage compound desferriferricrocin (DFFC). | CPCA. | 0.584 |
sidA | enoA | G5EB76 | Q5B135 | L-ornithine N(5)-monooxygenase; Catalyzes the conversion of L-ornithine to N(5)- hydroxyornithine, the first step in the biosynthesis of all hydroxamate-containing siderophores, such as the secreted triacetylfusarinine C (TAFC) involved in iron uptake and the intracellular iron storage compound desferriferricrocin (DFFC). | Enolase; Involved in osmoadaptation. | 0.623 |
sidA | mirA | G5EB76 | Q8X1Z7 | L-ornithine N(5)-monooxygenase; Catalyzes the conversion of L-ornithine to N(5)- hydroxyornithine, the first step in the biosynthesis of all hydroxamate-containing siderophores, such as the secreted triacetylfusarinine C (TAFC) involved in iron uptake and the intracellular iron storage compound desferriferricrocin (DFFC). | Siderophore iron transporter mirA; Involved in the transport of siderophore enterobactin and so has a role in iron homeostasis; Belongs to the major facilitator superfamily. | 0.408 |