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velB velB veA veA ANIA_06318 ANIA_06318 pyrG pyrG chsC chsC chsD chsD chsB chsB ANIA_04367 ANIA_04367 ANIA_00799 ANIA_00799 mpkC mpkC hog1 hog1 ANIA_06317 ANIA_06317 mpkB mpkB laeA laeA
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
Predicted Interactions
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velBVelvet complex subunit B; Component of the velvet transcription factor complex that controls sexual/asexual developmental ratio in response to light, promoting sexual development in the darkness while stimulating asexual sporulation under illumination. The velvet complex acts as a global regulator for secondary metabolite gene expression. Component of the velB-VosA heterodimeric complex that plays a dual role in activating genes associated with spore maturation and repressing certain development-associated genes. The velB-VosA complex binds DNA through the DNA-binding domain of vosA th [...] (369 aa)
veADevelopmental and secondary metabolism regulator veA; Component of the velvet transcription factor complex that controls sexual/asexual developmental ratio in response to light, promoting sexual development in the darkness while stimulating asexual sporulation under illumination. The velvet complex acts as a global regulator for secondary metabolite gene expression. Controls the expression of the sterigmatocystin and penicillin gene clusters. Represses the cryptic ors gene cluster producing orsellinic acid and its F9775 derivatives in a laeA-independent manner. Required for full induct [...] (573 aa)
ANIA_06318Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1852 aa)
pyrGOrotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. (274 aa)
chsCChitin synthase C; Plays a major role in cell wall biogenesis. (918 aa)
chsDChitin synthase D; Plays a major role in cell wall biogenesis. (1194 aa)
chsBChitin synthase B; Plays a major role in cell wall biogenesis. (916 aa)
ANIA_04367Chitin synthase; Plays a major role in cell wall biogenesis. (905 aa)
ANIA_00799Chitin synthase; Plays a major role in cell wall biogenesis. (797 aa)
mpkCMitogen-activated protein kinase mpkC; Mitogen-activated protein kinase required for growth on media where sorbitol or mannitol is the sole carbon source. (415 aa)
hog1Mitogen-activated protein kinase hog1; Mitogen-activated protein kinase involved in a signal transduction pathway that is activated by changes in the osmolarity of the extracellular environment. Controls osmotic regulation of transcription of target genes; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. HOG1 sub-subfamily. (379 aa)
ANIA_06317Chitin synthase. (1739 aa)
mpkBMitogen-activated protein kinase. (354 aa)
laeASecondary metabolism regulator laeA; Methyltransferase that performs automethylation at Met-207. No other methyl-accepting substrate has been identified yet. Component of the velvet transcription factor complex that acts as a global regulator for secondary metabolite gene expression. Controls the expression of the sterigmatocystin, penicillin, and lovastatin gene clusters. Controls light-dependent formation of the velB-vosA complex, veA protein modification, and is required for light-mediated inhibition of sexual development. Within the velvet complex, controls light-dependent secondar [...] (374 aa)
Your Current Organism:
Aspergillus nidulans
NCBI taxonomy Id: 227321
Other names: A. nidulans FGSC A4, Aspergillus nidulans FGSC A4, Emericella nidulans FGSC A4
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