13 items (Aspergillus nidulans) - STRING interaction network

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	riboB	GTP cyclohydrolase II, putative (AFU_orthologue AFUA_1G13300). (385 aa)
	ANIA_02911	AtfA. (485 aa)
	ANIA_04859	Plasma membrane ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily. (990 aa)
	pyroA	Pyridoxal 5'-phosphate synthase subunit pyroA; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by PDX2. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme- catalyzed isomerization of RBP and G3P, respectively. Also plays an indirect role in resistance to singlet oxygen-generating photosensitizers; Belongs to the PdxS/SNZ family. (304 aa)
	palC	pH-response regulator protein palC; Required for the proteolytic cleavage of the transcription factor pacC in response to alkaline ambient pH. (507 aa)
	palH	pH-response regulator protein palH/RIM21; Required for the proteolytic cleavage of the transcription factor pacC in response to alkaline ambient pH. Might be a pH sensor. Belongs to the palH/RIM21 family. (760 aa)
	hog1	Mitogen-activated protein kinase hog1; Mitogen-activated protein kinase involved in a signal transduction pathway that is activated by changes in the osmolarity of the extracellular environment. Controls osmotic regulation of transcription of target genes; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. HOG1 sub-subfamily. (379 aa)
	ANIA_00318	Plasma membrane ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily. (931 aa)
	palB	Calpain-like protease palB; Required for the proteolytic cleavage of the transcription factor pacC in response to alkaline ambient pH. Probably is the signaling protease that mediates the first proteolytic cleavage within the signaling protease box of pacC, yielding the 53 kDa 'open' conformation intermediate protein, which is committed to further processing. Required for virulence in invasive pulmonary aspergillosis (IPA). (847 aa)
	pacC	pH-response transcription factor pacC/RIM101 closed form; Transcription factor that mediates regulation of both acid- and alkaline-expressed genes in response to ambient pH. At alkaline ambient pH, activates transcription of alkaline-expressed genes (including pacC itself) and represses transcription of acid- expressed genes. Specifically recognizes and binds the consensus sequence 5'-GCCARG-3'. Required for virulence in invasive pulmonary aspergillosis (IPA). (678 aa)
	palF	pH-response regulator protein palF/RIM8; Required for the proteolytic cleavage of the transcription factor pacC in response to alkaline ambient pH. (775 aa)
	pyrG	Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. (274 aa)
	ipnA	Isopenicillin N synthase; Removes, in the presence of oxygen, 4 hydrogen atoms from delta-L-(alpha-aminoadipyl)-L-cysteinyl-D-valine (ACV) to form the azetidinone and thiazolidine rings of isopenicillin. (331 aa)

Your Current Organism:

Aspergillus nidulans

NCBI taxonomy Id: 227321
Other names: A. nidulans FGSC A4, Aspergillus nidulans FGSC A4, Emericella nidulans FGSC A4

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANIA_00318	ANIA_04859	Q5BGL2	G5EB90	Plasma membrane ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily.	Plasma membrane ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily.	0.903
ANIA_02911	hog1	C8VJ72	Q9P419	AtfA.	Mitogen-activated protein kinase hog1; Mitogen-activated protein kinase involved in a signal transduction pathway that is activated by changes in the osmolarity of the extracellular environment. Controls osmotic regulation of transcription of target genes; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. HOG1 sub-subfamily.	0.969
ANIA_04859	ANIA_00318	G5EB90	Q5BGL2	Plasma membrane ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily.	Plasma membrane ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily.	0.903
hog1	ANIA_02911	Q9P419	C8VJ72	Mitogen-activated protein kinase hog1; Mitogen-activated protein kinase involved in a signal transduction pathway that is activated by changes in the osmolarity of the extracellular environment. Controls osmotic regulation of transcription of target genes; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. HOG1 sub-subfamily.	AtfA.	0.969
hog1	pacC	Q9P419	Q00202	Mitogen-activated protein kinase hog1; Mitogen-activated protein kinase involved in a signal transduction pathway that is activated by changes in the osmolarity of the extracellular environment. Controls osmotic regulation of transcription of target genes; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. HOG1 sub-subfamily.	pH-response transcription factor pacC/RIM101 closed form; Transcription factor that mediates regulation of both acid- and alkaline-expressed genes in response to ambient pH. At alkaline ambient pH, activates transcription of alkaline-expressed genes (including pacC itself) and represses transcription of acid- expressed genes. Specifically recognizes and binds the consensus sequence 5'-GCCARG-3'. Required for virulence in invasive pulmonary aspergillosis (IPA).	0.522
ipnA	pacC	P05326	Q00202	Isopenicillin N synthase; Removes, in the presence of oxygen, 4 hydrogen atoms from delta-L-(alpha-aminoadipyl)-L-cysteinyl-D-valine (ACV) to form the azetidinone and thiazolidine rings of isopenicillin.	pH-response transcription factor pacC/RIM101 closed form; Transcription factor that mediates regulation of both acid- and alkaline-expressed genes in response to ambient pH. At alkaline ambient pH, activates transcription of alkaline-expressed genes (including pacC itself) and represses transcription of acid- expressed genes. Specifically recognizes and binds the consensus sequence 5'-GCCARG-3'. Required for virulence in invasive pulmonary aspergillosis (IPA).	0.483
pacC	hog1	Q00202	Q9P419	pH-response transcription factor pacC/RIM101 closed form; Transcription factor that mediates regulation of both acid- and alkaline-expressed genes in response to ambient pH. At alkaline ambient pH, activates transcription of alkaline-expressed genes (including pacC itself) and represses transcription of acid- expressed genes. Specifically recognizes and binds the consensus sequence 5'-GCCARG-3'. Required for virulence in invasive pulmonary aspergillosis (IPA).	Mitogen-activated protein kinase hog1; Mitogen-activated protein kinase involved in a signal transduction pathway that is activated by changes in the osmolarity of the extracellular environment. Controls osmotic regulation of transcription of target genes; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. HOG1 sub-subfamily.	0.522
pacC	ipnA	Q00202	P05326	pH-response transcription factor pacC/RIM101 closed form; Transcription factor that mediates regulation of both acid- and alkaline-expressed genes in response to ambient pH. At alkaline ambient pH, activates transcription of alkaline-expressed genes (including pacC itself) and represses transcription of acid- expressed genes. Specifically recognizes and binds the consensus sequence 5'-GCCARG-3'. Required for virulence in invasive pulmonary aspergillosis (IPA).	Isopenicillin N synthase; Removes, in the presence of oxygen, 4 hydrogen atoms from delta-L-(alpha-aminoadipyl)-L-cysteinyl-D-valine (ACV) to form the azetidinone and thiazolidine rings of isopenicillin.	0.483
pacC	palB	Q00202	Q00204	pH-response transcription factor pacC/RIM101 closed form; Transcription factor that mediates regulation of both acid- and alkaline-expressed genes in response to ambient pH. At alkaline ambient pH, activates transcription of alkaline-expressed genes (including pacC itself) and represses transcription of acid- expressed genes. Specifically recognizes and binds the consensus sequence 5'-GCCARG-3'. Required for virulence in invasive pulmonary aspergillosis (IPA).	Calpain-like protease palB; Required for the proteolytic cleavage of the transcription factor pacC in response to alkaline ambient pH. Probably is the signaling protease that mediates the first proteolytic cleavage within the signaling protease box of pacC, yielding the 53 kDa 'open' conformation intermediate protein, which is committed to further processing. Required for virulence in invasive pulmonary aspergillosis (IPA).	0.977
pacC	palC	Q00202	Q9P905	pH-response transcription factor pacC/RIM101 closed form; Transcription factor that mediates regulation of both acid- and alkaline-expressed genes in response to ambient pH. At alkaline ambient pH, activates transcription of alkaline-expressed genes (including pacC itself) and represses transcription of acid- expressed genes. Specifically recognizes and binds the consensus sequence 5'-GCCARG-3'. Required for virulence in invasive pulmonary aspergillosis (IPA).	pH-response regulator protein palC; Required for the proteolytic cleavage of the transcription factor pacC in response to alkaline ambient pH.	0.926
pacC	palF	Q00202	P78612	pH-response transcription factor pacC/RIM101 closed form; Transcription factor that mediates regulation of both acid- and alkaline-expressed genes in response to ambient pH. At alkaline ambient pH, activates transcription of alkaline-expressed genes (including pacC itself) and represses transcription of acid- expressed genes. Specifically recognizes and binds the consensus sequence 5'-GCCARG-3'. Required for virulence in invasive pulmonary aspergillosis (IPA).	pH-response regulator protein palF/RIM8; Required for the proteolytic cleavage of the transcription factor pacC in response to alkaline ambient pH.	0.972
pacC	palH	Q00202	Q9P904	pH-response transcription factor pacC/RIM101 closed form; Transcription factor that mediates regulation of both acid- and alkaline-expressed genes in response to ambient pH. At alkaline ambient pH, activates transcription of alkaline-expressed genes (including pacC itself) and represses transcription of acid- expressed genes. Specifically recognizes and binds the consensus sequence 5'-GCCARG-3'. Required for virulence in invasive pulmonary aspergillosis (IPA).	pH-response regulator protein palH/RIM21; Required for the proteolytic cleavage of the transcription factor pacC in response to alkaline ambient pH. Might be a pH sensor. Belongs to the palH/RIM21 family.	0.936
pacC	pyrG	Q00202	P10652	pH-response transcription factor pacC/RIM101 closed form; Transcription factor that mediates regulation of both acid- and alkaline-expressed genes in response to ambient pH. At alkaline ambient pH, activates transcription of alkaline-expressed genes (including pacC itself) and represses transcription of acid- expressed genes. Specifically recognizes and binds the consensus sequence 5'-GCCARG-3'. Required for virulence in invasive pulmonary aspergillosis (IPA).	Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family.	0.627
palB	pacC	Q00204	Q00202	Calpain-like protease palB; Required for the proteolytic cleavage of the transcription factor pacC in response to alkaline ambient pH. Probably is the signaling protease that mediates the first proteolytic cleavage within the signaling protease box of pacC, yielding the 53 kDa 'open' conformation intermediate protein, which is committed to further processing. Required for virulence in invasive pulmonary aspergillosis (IPA).	pH-response transcription factor pacC/RIM101 closed form; Transcription factor that mediates regulation of both acid- and alkaline-expressed genes in response to ambient pH. At alkaline ambient pH, activates transcription of alkaline-expressed genes (including pacC itself) and represses transcription of acid- expressed genes. Specifically recognizes and binds the consensus sequence 5'-GCCARG-3'. Required for virulence in invasive pulmonary aspergillosis (IPA).	0.977
palB	palC	Q00204	Q9P905	Calpain-like protease palB; Required for the proteolytic cleavage of the transcription factor pacC in response to alkaline ambient pH. Probably is the signaling protease that mediates the first proteolytic cleavage within the signaling protease box of pacC, yielding the 53 kDa 'open' conformation intermediate protein, which is committed to further processing. Required for virulence in invasive pulmonary aspergillosis (IPA).	pH-response regulator protein palC; Required for the proteolytic cleavage of the transcription factor pacC in response to alkaline ambient pH.	0.964
palB	palF	Q00204	P78612	Calpain-like protease palB; Required for the proteolytic cleavage of the transcription factor pacC in response to alkaline ambient pH. Probably is the signaling protease that mediates the first proteolytic cleavage within the signaling protease box of pacC, yielding the 53 kDa 'open' conformation intermediate protein, which is committed to further processing. Required for virulence in invasive pulmonary aspergillosis (IPA).	pH-response regulator protein palF/RIM8; Required for the proteolytic cleavage of the transcription factor pacC in response to alkaline ambient pH.	0.963
palB	palH	Q00204	Q9P904	Calpain-like protease palB; Required for the proteolytic cleavage of the transcription factor pacC in response to alkaline ambient pH. Probably is the signaling protease that mediates the first proteolytic cleavage within the signaling protease box of pacC, yielding the 53 kDa 'open' conformation intermediate protein, which is committed to further processing. Required for virulence in invasive pulmonary aspergillosis (IPA).	pH-response regulator protein palH/RIM21; Required for the proteolytic cleavage of the transcription factor pacC in response to alkaline ambient pH. Might be a pH sensor. Belongs to the palH/RIM21 family.	0.932
palC	pacC	Q9P905	Q00202	pH-response regulator protein palC; Required for the proteolytic cleavage of the transcription factor pacC in response to alkaline ambient pH.	pH-response transcription factor pacC/RIM101 closed form; Transcription factor that mediates regulation of both acid- and alkaline-expressed genes in response to ambient pH. At alkaline ambient pH, activates transcription of alkaline-expressed genes (including pacC itself) and represses transcription of acid- expressed genes. Specifically recognizes and binds the consensus sequence 5'-GCCARG-3'. Required for virulence in invasive pulmonary aspergillosis (IPA).	0.926
palC	palB	Q9P905	Q00204	pH-response regulator protein palC; Required for the proteolytic cleavage of the transcription factor pacC in response to alkaline ambient pH.	Calpain-like protease palB; Required for the proteolytic cleavage of the transcription factor pacC in response to alkaline ambient pH. Probably is the signaling protease that mediates the first proteolytic cleavage within the signaling protease box of pacC, yielding the 53 kDa 'open' conformation intermediate protein, which is committed to further processing. Required for virulence in invasive pulmonary aspergillosis (IPA).	0.964
palC	palF	Q9P905	P78612	pH-response regulator protein palC; Required for the proteolytic cleavage of the transcription factor pacC in response to alkaline ambient pH.	pH-response regulator protein palF/RIM8; Required for the proteolytic cleavage of the transcription factor pacC in response to alkaline ambient pH.	0.928