12 items (Aspergillus nidulans) - STRING interaction network

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	mdpE	Monodictyphenone cluster transcription factor; Transcription factor that regulates the expression of the gene cluster that mediates the biosynthesis of monodictyphenone, a prenyl xanthone derivative. (435 aa)
	mdpA	Monodictyphenone cluster transcriptional coactivator mdpA; Transcriptional coactivator; part of the gene cluster that mediates the biosynthesis of monodictyphenone, a prenyl xanthone derivative. With mdpE, coregulates the production of monodictyphenone. (479 aa)
	pyroA	Pyridoxal 5'-phosphate synthase subunit pyroA; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by PDX2. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme- catalyzed isomerization of RBP and G3P, respectively. Also plays an indirect role in resistance to singlet oxygen-generating photosensitizers; Belongs to the PdxS/SNZ family. (304 aa)
	trpC	Multifunctional tryptophan biosynthesis protein; Trifunctional enzyme bearing the Gln amidotransferase (GATase) domain of anthranilate synthase, indole-glycerolphosphate synthase, and phosphoribosylanthranilate isomerase activities. (768 aa)
	nirA	Nitrogen assimilation transcription factor nirA; Pathway-specific regulatory gene of nitrate assimilation; it activates the transcription of the genes for nitrate and nitrite reductases (niaD and niiA). (892 aa)
	niaD	Nitrate reductase [NADPH]; Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria. (873 aa)
	niiA	Nitrite reductase [NAD(P)H]; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (1104 aa)
	gpdA	Glyceraldehyde-3-phosphate dehydrogenase; Involved in osmoadaptation; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (336 aa)
	acnA	Actin, gamma; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells; Belongs to the actin family. (375 aa)
	afoA	Asperfuranone cluster transcription factor afoA; Transcription factor that regulates the expression of the gene cluster that mediates the biosynthesis of asperfuranone, a probable antitumor agent. (666 aa)
	mdpG	Atrochrysone carboxylic acid synthase; Non-reducing polyketide synthase; part of the gene cluster that mediates the biosynthesis of monodictyphenone, a prenyl xanthone derivative. The pathway begins with the synthesis of atrochrysone thioester by the polyketide synthase (PKS) mdpG. The atrochrysone carboxyl ACP thioesterase mdpF then breaks the thioester bond and releases the atrochrysone carboxylic acid from mdpG. The atrochrysone carboxylic acid is then converted to atrochrysone which is further transformed into emodin anthrone. The next step is performed by the anthrone oxygenase md [...] (1806 aa)
	mdpF	Atrochrysone carboxyl ACP thioesterase; Atrochrysone carboxyl ACP thioesterase; part of the gene cluster that mediates the biosynthesis of monodictyphenone, a prenyl xanthone derivative. The pathway begins with the synthesis of atrochrysone thioester by the polyketide synthase (PKS) mdpG. The atrochrysone carboxyl ACP thioesterase mdpF then breaks the thioester bond and releases the atrochrysone carboxylic acid from mdpG. The atrochrysone carboxylic acid is then converted to atrochrysone which is further transformed into emodin anthrone. The next step is performed by the anthrone oxyge [...] (307 aa)

Your Current Organism:

Aspergillus nidulans

NCBI taxonomy Id: 227321
Other names: A. nidulans FGSC A4, Aspergillus nidulans FGSC A4, Emericella nidulans FGSC A4

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
acnA	gpdA	P20359	P20445	Actin, gamma; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells; Belongs to the actin family.	Glyceraldehyde-3-phosphate dehydrogenase; Involved in osmoadaptation; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.	0.840
acnA	trpC	P20359	P06531	Actin, gamma; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells; Belongs to the actin family.	Multifunctional tryptophan biosynthesis protein; Trifunctional enzyme bearing the Gln amidotransferase (GATase) domain of anthranilate synthase, indole-glycerolphosphate synthase, and phosphoribosylanthranilate isomerase activities.	0.583
afoA	gpdA	Q5BEK1	P20445	Asperfuranone cluster transcription factor afoA; Transcription factor that regulates the expression of the gene cluster that mediates the biosynthesis of asperfuranone, a probable antitumor agent.	Glyceraldehyde-3-phosphate dehydrogenase; Involved in osmoadaptation; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.	0.415
gpdA	acnA	P20445	P20359	Glyceraldehyde-3-phosphate dehydrogenase; Involved in osmoadaptation; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.	Actin, gamma; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells; Belongs to the actin family.	0.840
gpdA	afoA	P20445	Q5BEK1	Glyceraldehyde-3-phosphate dehydrogenase; Involved in osmoadaptation; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.	Asperfuranone cluster transcription factor afoA; Transcription factor that regulates the expression of the gene cluster that mediates the biosynthesis of asperfuranone, a probable antitumor agent.	0.415
gpdA	niaD	P20445	P22945	Glyceraldehyde-3-phosphate dehydrogenase; Involved in osmoadaptation; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.	Nitrate reductase [NADPH]; Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria.	0.463
gpdA	pyroA	P20445	Q9UW83	Glyceraldehyde-3-phosphate dehydrogenase; Involved in osmoadaptation; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.	Pyridoxal 5'-phosphate synthase subunit pyroA; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by PDX2. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme- catalyzed isomerization of RBP and G3P, respectively. Also plays an indirect role in resistance to singlet oxygen-generating photosensitizers; Belongs to the PdxS/SNZ family.	0.717
gpdA	trpC	P20445	P06531	Glyceraldehyde-3-phosphate dehydrogenase; Involved in osmoadaptation; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.	Multifunctional tryptophan biosynthesis protein; Trifunctional enzyme bearing the Gln amidotransferase (GATase) domain of anthranilate synthase, indole-glycerolphosphate synthase, and phosphoribosylanthranilate isomerase activities.	0.974
mdpA	mdpE	C8VQ72	Q5BH32	Monodictyphenone cluster transcriptional coactivator mdpA; Transcriptional coactivator; part of the gene cluster that mediates the biosynthesis of monodictyphenone, a prenyl xanthone derivative. With mdpE, coregulates the production of monodictyphenone.	Monodictyphenone cluster transcription factor; Transcription factor that regulates the expression of the gene cluster that mediates the biosynthesis of monodictyphenone, a prenyl xanthone derivative.	0.883
mdpA	mdpF	C8VQ72	Q5BH31	Monodictyphenone cluster transcriptional coactivator mdpA; Transcriptional coactivator; part of the gene cluster that mediates the biosynthesis of monodictyphenone, a prenyl xanthone derivative. With mdpE, coregulates the production of monodictyphenone.	Atrochrysone carboxyl ACP thioesterase; Atrochrysone carboxyl ACP thioesterase; part of the gene cluster that mediates the biosynthesis of monodictyphenone, a prenyl xanthone derivative. The pathway begins with the synthesis of atrochrysone thioester by the polyketide synthase (PKS) mdpG. The atrochrysone carboxyl ACP thioesterase mdpF then breaks the thioester bond and releases the atrochrysone carboxylic acid from mdpG. The atrochrysone carboxylic acid is then converted to atrochrysone which is further transformed into emodin anthrone. The next step is performed by the anthrone oxyge [...]	0.762
mdpA	mdpG	C8VQ72	Q5BH30	Monodictyphenone cluster transcriptional coactivator mdpA; Transcriptional coactivator; part of the gene cluster that mediates the biosynthesis of monodictyphenone, a prenyl xanthone derivative. With mdpE, coregulates the production of monodictyphenone.	Atrochrysone carboxylic acid synthase; Non-reducing polyketide synthase; part of the gene cluster that mediates the biosynthesis of monodictyphenone, a prenyl xanthone derivative. The pathway begins with the synthesis of atrochrysone thioester by the polyketide synthase (PKS) mdpG. The atrochrysone carboxyl ACP thioesterase mdpF then breaks the thioester bond and releases the atrochrysone carboxylic acid from mdpG. The atrochrysone carboxylic acid is then converted to atrochrysone which is further transformed into emodin anthrone. The next step is performed by the anthrone oxygenase md [...]	0.721
mdpE	mdpA	Q5BH32	C8VQ72	Monodictyphenone cluster transcription factor; Transcription factor that regulates the expression of the gene cluster that mediates the biosynthesis of monodictyphenone, a prenyl xanthone derivative.	Monodictyphenone cluster transcriptional coactivator mdpA; Transcriptional coactivator; part of the gene cluster that mediates the biosynthesis of monodictyphenone, a prenyl xanthone derivative. With mdpE, coregulates the production of monodictyphenone.	0.883
mdpE	mdpG	Q5BH32	Q5BH30	Monodictyphenone cluster transcription factor; Transcription factor that regulates the expression of the gene cluster that mediates the biosynthesis of monodictyphenone, a prenyl xanthone derivative.	Atrochrysone carboxylic acid synthase; Non-reducing polyketide synthase; part of the gene cluster that mediates the biosynthesis of monodictyphenone, a prenyl xanthone derivative. The pathway begins with the synthesis of atrochrysone thioester by the polyketide synthase (PKS) mdpG. The atrochrysone carboxyl ACP thioesterase mdpF then breaks the thioester bond and releases the atrochrysone carboxylic acid from mdpG. The atrochrysone carboxylic acid is then converted to atrochrysone which is further transformed into emodin anthrone. The next step is performed by the anthrone oxygenase md [...]	0.625
mdpF	mdpA	Q5BH31	C8VQ72	Atrochrysone carboxyl ACP thioesterase; Atrochrysone carboxyl ACP thioesterase; part of the gene cluster that mediates the biosynthesis of monodictyphenone, a prenyl xanthone derivative. The pathway begins with the synthesis of atrochrysone thioester by the polyketide synthase (PKS) mdpG. The atrochrysone carboxyl ACP thioesterase mdpF then breaks the thioester bond and releases the atrochrysone carboxylic acid from mdpG. The atrochrysone carboxylic acid is then converted to atrochrysone which is further transformed into emodin anthrone. The next step is performed by the anthrone oxyge [...]	Monodictyphenone cluster transcriptional coactivator mdpA; Transcriptional coactivator; part of the gene cluster that mediates the biosynthesis of monodictyphenone, a prenyl xanthone derivative. With mdpE, coregulates the production of monodictyphenone.	0.762
mdpF	mdpG	Q5BH31	Q5BH30	Atrochrysone carboxyl ACP thioesterase; Atrochrysone carboxyl ACP thioesterase; part of the gene cluster that mediates the biosynthesis of monodictyphenone, a prenyl xanthone derivative. The pathway begins with the synthesis of atrochrysone thioester by the polyketide synthase (PKS) mdpG. The atrochrysone carboxyl ACP thioesterase mdpF then breaks the thioester bond and releases the atrochrysone carboxylic acid from mdpG. The atrochrysone carboxylic acid is then converted to atrochrysone which is further transformed into emodin anthrone. The next step is performed by the anthrone oxyge [...]	Atrochrysone carboxylic acid synthase; Non-reducing polyketide synthase; part of the gene cluster that mediates the biosynthesis of monodictyphenone, a prenyl xanthone derivative. The pathway begins with the synthesis of atrochrysone thioester by the polyketide synthase (PKS) mdpG. The atrochrysone carboxyl ACP thioesterase mdpF then breaks the thioester bond and releases the atrochrysone carboxylic acid from mdpG. The atrochrysone carboxylic acid is then converted to atrochrysone which is further transformed into emodin anthrone. The next step is performed by the anthrone oxygenase md [...]	0.921
mdpF	trpC	Q5BH31	P06531	Atrochrysone carboxyl ACP thioesterase; Atrochrysone carboxyl ACP thioesterase; part of the gene cluster that mediates the biosynthesis of monodictyphenone, a prenyl xanthone derivative. The pathway begins with the synthesis of atrochrysone thioester by the polyketide synthase (PKS) mdpG. The atrochrysone carboxyl ACP thioesterase mdpF then breaks the thioester bond and releases the atrochrysone carboxylic acid from mdpG. The atrochrysone carboxylic acid is then converted to atrochrysone which is further transformed into emodin anthrone. The next step is performed by the anthrone oxyge [...]	Multifunctional tryptophan biosynthesis protein; Trifunctional enzyme bearing the Gln amidotransferase (GATase) domain of anthranilate synthase, indole-glycerolphosphate synthase, and phosphoribosylanthranilate isomerase activities.	0.536
mdpG	mdpA	Q5BH30	C8VQ72	Atrochrysone carboxylic acid synthase; Non-reducing polyketide synthase; part of the gene cluster that mediates the biosynthesis of monodictyphenone, a prenyl xanthone derivative. The pathway begins with the synthesis of atrochrysone thioester by the polyketide synthase (PKS) mdpG. The atrochrysone carboxyl ACP thioesterase mdpF then breaks the thioester bond and releases the atrochrysone carboxylic acid from mdpG. The atrochrysone carboxylic acid is then converted to atrochrysone which is further transformed into emodin anthrone. The next step is performed by the anthrone oxygenase md [...]	Monodictyphenone cluster transcriptional coactivator mdpA; Transcriptional coactivator; part of the gene cluster that mediates the biosynthesis of monodictyphenone, a prenyl xanthone derivative. With mdpE, coregulates the production of monodictyphenone.	0.721
mdpG	mdpE	Q5BH30	Q5BH32	Atrochrysone carboxylic acid synthase; Non-reducing polyketide synthase; part of the gene cluster that mediates the biosynthesis of monodictyphenone, a prenyl xanthone derivative. The pathway begins with the synthesis of atrochrysone thioester by the polyketide synthase (PKS) mdpG. The atrochrysone carboxyl ACP thioesterase mdpF then breaks the thioester bond and releases the atrochrysone carboxylic acid from mdpG. The atrochrysone carboxylic acid is then converted to atrochrysone which is further transformed into emodin anthrone. The next step is performed by the anthrone oxygenase md [...]	Monodictyphenone cluster transcription factor; Transcription factor that regulates the expression of the gene cluster that mediates the biosynthesis of monodictyphenone, a prenyl xanthone derivative.	0.625
mdpG	mdpF	Q5BH30	Q5BH31	Atrochrysone carboxylic acid synthase; Non-reducing polyketide synthase; part of the gene cluster that mediates the biosynthesis of monodictyphenone, a prenyl xanthone derivative. The pathway begins with the synthesis of atrochrysone thioester by the polyketide synthase (PKS) mdpG. The atrochrysone carboxyl ACP thioesterase mdpF then breaks the thioester bond and releases the atrochrysone carboxylic acid from mdpG. The atrochrysone carboxylic acid is then converted to atrochrysone which is further transformed into emodin anthrone. The next step is performed by the anthrone oxygenase md [...]	Atrochrysone carboxyl ACP thioesterase; Atrochrysone carboxyl ACP thioesterase; part of the gene cluster that mediates the biosynthesis of monodictyphenone, a prenyl xanthone derivative. The pathway begins with the synthesis of atrochrysone thioester by the polyketide synthase (PKS) mdpG. The atrochrysone carboxyl ACP thioesterase mdpF then breaks the thioester bond and releases the atrochrysone carboxylic acid from mdpG. The atrochrysone carboxylic acid is then converted to atrochrysone which is further transformed into emodin anthrone. The next step is performed by the anthrone oxyge [...]	0.921
niaD	gpdA	P22945	P20445	Nitrate reductase [NADPH]; Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria.	Glyceraldehyde-3-phosphate dehydrogenase; Involved in osmoadaptation; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.	0.463